Clinical trials
Diabetes (Insulin-requiring, Type 1 or Type 2) clinical trials
Below are recruiting diabetes (insulin-requiring, type 1 or type 2) clinical trials, each written for real people, not researchers. We’re tracking 2,191 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04791371Recruiting
Study how fitness and insulin resistance relate to diabetes
This study looks at how low physical activity, insulin resistance in small blood vessels, and cardiorespiratory fitness connect to diabetes and blood sugar control. You may be eligible if you are generally sedentary and fit within the weight range, and if you do not have certain heart, lung, nerve, or medication factors.
Aurora, ColoradoAges 30–55 - NCT06007404Recruiting
Understanding metabolism and inflammation in teens
This study looks at how metabolism and inflammation relate to diabetes risk in teenagers. It may help researchers understand why some teens develop type 2 diabetes.
Ann Arbor, MichiganAges 14–18 - NCT05165706Recruiting
Study of how obesity affects insulin resistance over time
This study follows adults over time to understand how weight and body chemistry relate to insulin resistance. It may help researchers learn why insulin resistance happens and what could prevent or improve it.
Stanford, CaliforniaAges 35–65 - NCT05663515Recruiting
Checks pancreatic cancer risk after starting exenatide in type 2 diabetes
This study looks at whether starting exenatide (a type 2 diabetes medicine) is linked to a higher or lower risk of pancreatic cancer compared with other similar diabetes medicines. It uses people’s prescription and medical record history to compare risks over time.
CopenhagenAges 18–99 - NCT06283797Recruiting
Automated insulin early after type 1 diabetes diagnosis in kids
This trial tests whether starting automated insulin therapy soon after diagnosis helps children and teens with type 1 diabetes control their blood sugar better. It uses a system that automatically adjusts insulin delivery based on continuous glucose monitoring.
AngersAges 2–18 - NCT06363916Recruiting
Testing a new automated insulin delivery system for type 1 diabetes
This study tests a new hybrid closed-loop system (an automated insulin pump) in people with type 1 diabetes whose blood sugar is not well controlled. It aims to see if the system is safe and helps improve glucose levels.
AngersAges 7–75 - NCT06366399Recruiting
Timing of resistance exercise for weight management
This study tests if doing resistance exercises (like lifting weights) in the morning or afternoon is better for weight management. You may qualify if you are between 50 and 74 years old, are overweight but generally healthy, and have not been very active with strength training.
Salt Lake City, UtahAges 50–74 - NCT06638567Recruiting
Comparing insulin methods after surgery for type 2 diabetes
This trial tests two ways to give insulin after gastrointestinal or vascular surgery to see which one leads to fewer wound infections. It may help if you have type 2 diabetes and are having one of these surgeries.
AmsterdamAges 18 years+ - NCT06654713Recruiting
Closed-loop insulin system impact on pregnancy study
This study looks at how automated insulin delivery systems (closed-loop pumps) work during pregnancy for women with type 1 diabetes. It aims to understand how these systems can help manage blood sugar levels safely for both you and your baby.
San Francisco, CaliforniaAges 18 years+ - NCT06671587RecruitingPhase 4
Testing insulin/GLP-1 combo with CGM for type 2 diabetes
This study tests a combination insulin/GLP-1 medicine (iGlarLixi) with continuous glucose monitoring to see how well it controls blood sugar in Chinese adults with type 2 diabetes. It may help those whose current pills are not working enough.
BeijingAges 18 years+ - NCT06762314RecruitingPhase 2
Empagliflozin or semaglutide for overweight people with type 1 diabetes
This study tests two different medicines (empagliflozin or semaglutide) added to your usual insulin to see if they help with blood sugar control and weight loss in people with type 1 diabetes who are overweight or have obesity. It may be a good fit if your diabetes is not well controlled with insulin injections alone.
TantaAges 18–65 - NCT07066891Recruiting
AI insulin dose prediction for type 2 diabetes
This study tests an artificial intelligence system that helps predict the right insulin dose for people with type 2 diabetes who are using an insulin pump in the hospital. The goal is to make blood sugar control safer and more accurate.
Guangzhou, GuangdongAges 18–75 - NCT07109700RecruitingPhase 2
New injectable study for type 2 diabetes
This study tests a new once-weekly injectable medication (HDM1005) for people with type 2 diabetes whose blood sugar is not well controlled by diet and exercise or metformin alone. It aims to help lower blood sugar and may also support weight loss.
Beijing, Beijing MunicipalityAges 18–65 - NCT07121504Recruiting
Hybrid closed-loop insulin for blood sugar control during surgery
This trial tests a smart insulin pump system (hybrid closed-loop) to control blood sugar in people with type 2 diabetes who need surgery and will receive nutrition through a vein. It aims to prevent high and low blood sugar during and after surgery.
Changsha, HunanAges 18 years+ - NCT07146347RecruitingPhase 1
Comparing a new long-acting insulin for type 2 diabetes
This study tests a new once-daily insulin (GZR4) against an approved insulin (degludec) in people with type 2 diabetes to see how well it controls blood sugar. You may qualify if you are already using a stable dose of background insulin.
NeussAges 18–70 - NCT07173543Recruiting
Type 2 Diabetes and Brain Health Study for Adults 60–85
This study looks at how type 2 diabetes affects blood flow in the brain and thinking ability. It compares people with diabetes to those without, and may help understand how to protect brain health.
Iowa City, IowaAges 60–85 - NCT07297342Recruiting
Comparing ways to use the 'Get Ready' app for weight loss surgery
This study compares two ways of using a smartphone app called 'Get Ready' to help people follow their pre-surgery plan before weight loss surgery. It aims to see which approach helps patients stay on track better.
GeelAges Any age - NCT07309094Recruiting
Effects of a diabetes drug on fat tissue in kidney disease
This trial tests whether a GLP-1 receptor agonist (a type of diabetes medication) can improve fat tissue health in people with chronic kidney disease who also have type 2 diabetes, cardiovascular disease, or obesity. It may help protect your kidneys and overall health.
Valencia, ValenciaAges 18–90 - NCT01477957Recruiting
Bariatric surgery and changes in insulin and body energy use
This study tests whether weight-loss surgery improves how your body uses insulin and energy. It compares insulin sensitivity and related measurements before and after surgery to understand who benefits.
Düsseldorf, North Rhine-WestphaliaAges 20–70 - NCT07507708Recruiting
Smart insulin system with behavior support for type 1 diabetes
This study tests a smart insulin pump and continuous glucose monitor system that adjusts insulin automatically and uses behavior support to improve blood sugar control. It's for people with type 1 diabetes who have used an approved automated insulin delivery system recently and are willing to use study devices.
Charlottesville, VirginiaAges 18 years+ - NCT07535307RecruitingPhase 1
Testing NNC0487-0111 to regulate insulin in type 2 diabetes
This early-stage study tests a new experimental drug (NNC0487-0111) designed to help regulate insulin levels in adults with type 2 diabetes. Researchers want to see if it works safely and effectively when combined with your current diabetes medications.
NeussAges 18–75 - NCT07621419Recruiting
Semaglutide for Type 2 Diabetes in Real-World Care
This study tests how well a diabetes medication called semaglutide works when prescribed in everyday clinical practice in Argentina. Semaglutide comes in two forms—a pill or an injection—and the study tracks how much it lowers blood sugar over one year.
Buenos Aires, Buenos AiresAges 18 years+ - NCT07422831Enrolling by invitation
Intermittent glucose sensor use for type 2 diabetes
This trial is testing whether using a continuous glucose monitor (CGM) for different lengths of time helps people with type 2 diabetes understand their blood sugar patterns. You won't need to change your current diabetes medications.
Aurora, ColoradoAges 18 years+ - NCT07197788Enrolling by invitation
Continued access to the Endogenex device study for type 2 diabetes
This trial offers continued access to the Endogenex system for people who were in the sham (placebo) group of the ReCET study and have completed their 12-month visit. It tests a device that treats the duodenum to improve blood sugar control.
Miami, FloridaAges 22 years+
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Common questions
- Are there clinical trials for diabetes (insulin-requiring, type 1 or type 2)?
- Yes. Clin2 currently lists 2,191 recruiting diabetes (insulin-requiring, type 1 or type 2) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a diabetes (insulin-requiring, type 1 or type 2) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a diabetes (insulin-requiring, type 1 or type 2) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.