Clinical trials
Diabetes (Insulin-requiring, Type 1 or Type 2) clinical trials
Below are recruiting diabetes (insulin-requiring, type 1 or type 2) clinical trials, each written for real people, not researchers. We’re tracking 2,148 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06893341Recruiting
Breath Device to Detect Blood Sugar Changes in Teens
This study tests if a breath device can spot high or low blood sugar in teens with type 1 diabetes without a fingerstick. Participants will use the device a few times and share their CGM data.
Indianapolis, IndianaAges 12–19 - NCT06886126RecruitingPhase 2
Testing HDM1005 injection for weight loss in adults with obesity
This study tests an experimental injection called HDM1005 for adults with obesity who do not have diabetes. The goal is to see if it helps with weight loss when combined with diet and exercise.
NanjingAges 18–65 - NCT06885736Recruiting
Preserving muscle with exercise and protein on weight loss drugs
This trial tests whether adding resistance exercise and extra protein can help you keep your muscle while taking weight loss medications like semaglutide or tirzepatide. It is for people with a BMI of 27 or higher who are not already exercising regularly.
Kuwait CityAges 18 years+ - NCT06875830Recruiting
Immediate tooth replacement with mesh vs. membrane for damaged front teeth
This trial compares two materials—titanium mesh and collagen membrane—used to support a new tooth implant placed right after removing a badly decayed tooth in the upper front area. It aims to see which material works better when the bone around the tooth is partially damaged.
Cairo, Heliopolis - CairoAges 21–50 - NCT06873945RecruitingPhase 3
Study of two doses of ritlecitinib for alopecia areata
This study tests two different doses of a pill called ritlecitinib to see if it can help regrow hair in people with significant hair loss from alopecia areata. It is for people aged 12 and older who have lost at least half of their scalp hair.
Birmingham, AlabamaAges 12 years+ - NCT06874335RecruitingPhase 1
A study of BHV-1530 for advanced solid tumors
This trial tests a new drug, BHV-1530, either alone or with another drug called cemiplimab, for people with certain advanced solid tumors that have stopped responding to standard treatments. The goal is to see if it's safe and effective.
Newport Beach, CaliforniaAges 18 years+ - NCT06402435RecruitingPhase 2
Combination therapy before surgery for hormone positive breast cancer
This trial tests a new combination of treatments given before surgery for hormone receptor positive, HER2 negative breast cancer. It uses stereotactic body radiation therapy (SBRT), chemotherapy, and an investigational drug called AK112 to shrink tumors and make surgery easier.
Wuhan, HubeiAges 18 years+ - NCT06860594RecruitingPhase 1
Triapine plus radiation for recurrent brain tumors
This trial tests whether adding an experimental drug called triapine to a second round of radiation therapy can help treat brain tumors that have come back after initial treatment. It may be a good option for people with recurrent glioblastoma or astrocytoma who meet safety criteria.
Duarte, CaliforniaAges 18 years+ - NCT06852469RecruitingPhase 4
GABA test for PTSD in veterans
This trial uses a medication called lorazepam to study how GABA receptors work in veterans with PTSD. It aims to learn more about brain chemistry related to PTSD and how it might affect treatment.
San Diego, CaliforniaAges 18–65 - NCT06855745RecruitingPhase 2
Testing a new gel for mild to moderate eczema
This study tests a new gel called Zabalafin Hydrogel to see if it helps people with mild to moderate atopic dermatitis (eczema). The gel is applied directly to the skin. If you or your child has eczema on the head, neck, trunk, or limbs, this trial may be an option.
Brookvale, New South WalesAges 2 years+ - NCT06854653RecruitingPhase 2
PTX 100 for relapsed CTCL
This trial tests an experimental drug called PTX 100 for people with cutaneous T-cell lymphoma (CTCL) that has come back after at least two prior treatments. It aims to see if PTX 100 can help shrink tumors or slow the disease.
Duarte, CaliforniaAges 18 years+ - NCT06849908RecruitingPhase 2
Baricitinib for treating intestinal Behçet's disease
This trial tests baricitinib, an oral medication, for people with intestinal Behçet's disease that hasn't improved with standard treatments. It aims to see if baricitinib can reduce symptoms and help heal gut ulcers.
Beijing, Beijing MunicipalityAges 18–65 - NCT06842173RecruitingPhase 1/Phase 2
Safety testing of new bird flu vaccine (H5N8) in adults
This trial tests a new bird flu (H5N8) vaccine for adults aged 18 and older. It looks at how safe the vaccine is and how well it triggers an immune response. The vaccine is given as a shot and includes an adjuvant to boost protection.
Belo Horizonte, Minas GeraisAges 18 years+ - NCT06827990Recruiting
Stent graft for type A aortic dissection
This trial tests a stent graft device to repair a tear in the main artery from the heart (aorta). It is for people who have a high-risk condition called Type A aortic dissection and are not good candidates for open heart surgery.
Birmingham, AlabamaAges 18 years+ - NCT06830629RecruitingPhase 2
MZE829 for APOL1 kidney disease
This trial tests an experimental drug called MZE829 for people with kidney disease linked to the APOL1 gene. It aims to see if the drug can help protect kidney function.
Decatur, AlabamaAges 18–68 - NCT06828588RecruitingEarly Phase 1
A new imaging test for people on HER2 cancer therapy
This study tests a new imaging drug called [68Ga]Ga-ABY-025 to see how well it shows HER2-positive tumors in people who are about to start or have just started HER2-targeted cancer therapy. It may help doctors see if the treatment is working.
Nashville, TennesseeAges 18 years+ - NCT06835803RecruitingPhase 2
Intensified radiation for older adults with glioblastoma
This trial tests whether a more focused, stronger dose of radiation can improve outcomes for people 65 and older with newly diagnosed glioblastoma. It compares this approach to standard radiation to see if it's safe and effective.
Boston, MassachusettsAges 65 years+ - NCT06825559RecruitingPhase 1
Saroglitazar safety in moderate liver impairment from cholestatic disease
This trial tests how the body processes saroglitazar in people with moderate liver impairment caused by cholestatic liver disease. The goal is to ensure the drug is safe and dosed correctly for this group.
Indianapolis, IndianaAges 18–80 - NCT06811233RecruitingPhase 2
Metal detox during AML treatment
This trial tests whether monitoring and rebalancing metals in the body can help improve treatment for adults with acute myeloid leukemia (AML) or related conditions. It's for patients who are getting their first or second round of therapy and aren't yet in remission.
Houston, TexasAges 18 years+ - NCT06811324RecruitingPhase 2
Tirzepatide for muscle and vessel health in older adults
This study tests if the drug tirzepatide can improve muscle and blood vessel health in older adults with obesity. You may be eligible if you are 50 or older, have a BMI between 30 and 40, and do not have diabetes.
San Antonio, TexasAges 50 years+ - NCT06801665RecruitingPhase 2
Combination therapy for advanced colorectal cancer with liver spread
This trial tests a new combination of treatments for advanced colorectal cancer that has spread to the liver. It aims to see if this combination can shrink tumors and help patients live longer.
ChangzhouAges 18–75 - NCT06790784RecruitingPhase 3
Comparing faricimab plus laser vs. surgery for diabetic eye disease
This study compares two approaches to treat advanced diabetic eye disease (proliferative diabetic retinopathy): injections of faricimab plus laser, versus surgery (vitrectomy) with laser. It is for people with diabetes who need treatment for PDR and still have relatively good vision (20/100 or better) in the affected eye.
Huntington Beach, CaliforniaAges 18 years+ - NCT06781996RecruitingPhase 3
Digital tool to help manage hormone therapy side effects
This trial tests a digital tool (a smartphone app) to help women and men with early breast cancer manage side effects from hormone therapy. The goal is to improve quality of life during treatment.
VillejuifAges 18 years+ - NCT05929495RecruitingPhase 2
Metformin added to standard treatment for newly diagnosed glioblastoma
This Phase 2 study tests whether adding metformin to the usual treatment for newly diagnosed glioblastoma (GBM) can improve outcomes. It involves taking metformin after surgery along with standard care (the Stupp protocol).
MilanAges 18 years+
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Common questions
- Are there clinical trials for diabetes (insulin-requiring, type 1 or type 2)?
- Yes. Clin2 currently lists 2,148 recruiting diabetes (insulin-requiring, type 1 or type 2) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a diabetes (insulin-requiring, type 1 or type 2) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a diabetes (insulin-requiring, type 1 or type 2) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.