Clinical trials · California
Diabetes Mellitus clinical trials in California
We’re tracking 76 recruiting diabetes mellitus studies with a site in California — including Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT06217302RecruitingPhase 3
Sotagliflozin for kidney protection in type 1 diabetes
This study tests whether sotagliflozin (a pill that helps control blood sugar and protects the kidneys) can slow down kidney function decline in people with type 1 diabetes and diabetic kidney disease. You may qualify if you have had type 1 diabetes for at least 8 years, have moderate kidney damage, and are on standard treatments.
Stanford, CaliforniaAges 18–75 - NCT06919354RecruitingPhase 1
Study of GNTI-122 for new type 1 diabetes
This study tests a new treatment called GNTI-122 for adults recently diagnosed with type 1 diabetes who still make some insulin. It aims to see if the treatment can help protect the cells that produce insulin.
San Diego, CaliforniaAges 18–55 - NCT04783441Recruiting
Continuous glucose sensor study after kidney transplant
This study checks whether using a continuous glucose monitor (a sensor that tracks sugar throughout the day) is helpful and practical for people with a recent kidney transplant and type 2 diabetes on insulin. You may need to wear the sensor continuously and still do finger-stick glucose checks for safety.
Sacramento, CaliforniaAges 18 years+ - NCT06628453Recruiting
Continuous glucose monitor for type 2 diabetes in pregnancy
This study tests whether using a CGM (a small sensor that tracks blood sugar) can help manage type 2 diabetes during pregnancy better than standard care. It is for women who have type 2 diabetes and are pregnant with one baby.
San Diego, CaliforniaAges 18–50 - NCT02734277Recruiting
Extending a past Type 1 diabetes immune study
This study is for people who already took part in an earlier immune-tolerance program for Type 1 diabetes. It tests whether continuing follow-up and assessments can be done safely and may help learn more about long-term immune effects of treatment.
San Francisco, CaliforniaAges 8–35 - NCT07544407Enrolling by invitation
Text-Based Diabetes Support for Parents
This study helps parents newly diagnosed with type 2 diabetes learn to manage their condition while caring for young children. You'll receive text messages and join virtual sessions designed to support both your health and your family.
Pleasanton, CaliforniaAges 21–44 - NCT07351058RecruitingPhase 3
Enicepatide for weight loss in people with type 2 diabetes
This trial tests an investigational medication, Enicepatide, to see if it helps people with obesity or overweight and type 2 diabetes lose weight and improve blood sugar control. You will receive weekly injections and regular check-ups.
Irvine, CaliforniaAges 18 years+ - NCT07065721Recruiting
Continuous glucose monitors for young adults with type 2 diabetes
This trial tests if using a continuous glucose monitor (a small sensor that checks your sugar levels without fingersticks) helps young adults manage type 2 diabetes better. You will wear the sensor and use a phone app to track your glucose.
San Diego, CaliforniaAges 18–45 - NCT06739122RecruitingPhase 3
A study of dulaglutide for children with type 2 diabetes
This trial tests if a weekly injection of dulaglutide (Trulicity) can help children with type 2 diabetes control their blood sugar when used together with metformin and/or insulin. It may be an option for kids who are overweight.
Los Angeles, CaliforniaAges 10–17 - NCT07817251RecruitingPhase 3
Switching From Semaglutide to Cagrisema in Type 2 Diabetes
This study looks at how people with type 2 diabetes tolerate switching from a weekly semaglutide injection (like Ozempic or Wegovy) to a new experimental medicine called Cagrisema. The goal is to see if the switch is safe and effective.
Fountain Valley, CaliforniaAges 18 years+ - NCT07064473RecruitingPhase 3
Testing vicadrostat plus empagliflozin for diabetes, high blood pressure, and heart disease
This study tests a new pill called vicadrostat taken with another medicine (empagliflozin) to see if it helps people with type 2 diabetes, high blood pressure, and heart disease. It may reduce the risk of heart problems, but you must not have had heart failure or use certain other heart medications.
Beverly Hills, CaliforniaAges 18 years+ - NCT07743450RecruitingPhase 3
Daily oral medication for weight loss in adults with obesity and type 2 diabetes
This study tests a once-a-day pill for adults who are overweight or have obesity and also have type 2 diabetes. The goal is to see if the medication helps with weight loss and improves blood sugar control.
Banning, CaliforniaAges 18 years+ - NCT07222137RecruitingPhase 3
Baricitinib to delay type 1 diabetes in at-risk people
This trial tests if baricitinib, a pill that calms the immune system, can slow down or delay the onset of type 1 diabetes in children and adults who are at high risk. It is for people whose blood sugar is already starting to rise but who do not yet need insulin.
Santa Barbara, CaliforniaAges 1–35 - NCT07502508RecruitingPhase 2
Icovamenib for type 2 diabetes with Ozempic
This trial tests an investigational pill called icovamenib for people with type 2 diabetes who are already on Ozempic but still have high blood sugar. The goal is to see if adding icovamenib helps lower blood sugar more safely.
Montclair, CaliforniaAges 18–70 - NCT05831085Recruiting
Compare procedures to improve heart blood flow in diabetes
This study compares two ways to restore blood flow to the heart—stent placement (PCI) versus bypass surgery (CABG)—in people with diabetes and significant multi-vessel coronary artery disease. It looks at outcomes using both standard heart tests and additional imaging/functional measurements to guide the best revascularization strategy.
Palo Alto, CaliforniaAges 20 years+ - NCT07784725RecruitingPhase 3
Study of a weight loss injection for adults with obesity
This study tests a new medicine to help adults with obesity or overweight lose weight. It's for people who have had trouble losing weight in the past and don't have diabetes.
Escondido, CaliforniaAges 18 years+ - NCT07783802RecruitingPhase 2
Study of clazakizumab for adults with high inflammation and heart risk
This study tests whether clazakizumab can reduce the risk of heart attacks or strokes in people with high levels of inflammation (measured by a blood test called hsCRP) and conditions like heart disease, obesity, diabetes, high blood pressure, or kidney disease. If you qualify, you'll receive either the study drug or a placebo to see if it helps lower your risk.
Glendora, CaliforniaAges 18 years+ - NCT07684144RecruitingPhase 3
Long-term study of a weight-loss medication for people who completed an earlier trial
This study tests the long-term effects of a medication called maridebart cafraglutide for weight management. It is for people who already completed a 72-week study of this drug and want to continue treatment.
Canoga Park, CaliforniaAges 18–99 - NCT05165706Recruiting
Study of how obesity affects insulin resistance over time
This study follows adults over time to understand how weight and body chemistry relate to insulin resistance. It may help researchers learn why insulin resistance happens and what could prevent or improve it.
Stanford, CaliforniaAges 35–65 - NCT07296276Recruiting
Testing the CareSens Air 3 glucose monitor in type 1 diabetes
This study tests how accurate a new continuous glucose monitor (CGM) called CareSens Air 3 is for adults with type 1 diabetes. You would wear the sensor on your skin to track blood sugar levels, and it may help you manage your diabetes more easily.
Escondido, CaliforniaAges 18–65 - NCT06989164Recruiting
How Your Body Responds to Different Foods After Eating
This study looks at how different foods affect your body after eating, especially your blood sugar and other metabolic responses. It may help find personalized ways to eat better for your health.
Stanford, CaliforniaAges 18–80 - NCT06965803Recruiting
Does continuous glucose monitoring improve quality of life for people with diabetes?
This study tests if using a continuous glucose monitor (CGM) along with standard diabetes education helps people with diabetes feel more satisfied and have a better quality of life. You will be asked to wear a CGM device and complete surveys about your experience.
Los Angeles, CaliforniaAges 18 years+ - NCT06907147Recruiting
Renal denervation for uncontrolled high blood pressure
This trial tests a procedure called renal denervation to lower blood pressure in people whose medication isn't enough. It uses a special catheter to calm nerves near the kidneys that may be overactive.
Stanford, CaliforniaAges 18–80 - NCT06884059RecruitingPhase 1
Time-restricted eating for people with early kidney signs
This study tests whether eating only during a certain window each day helps people with type 2 diabetes and small amounts of protein in their urine (a sign of early kidney stress) improve their health. You'll use a smartphone app to log your meals and follow a daily eating schedule.
La Jolla, CaliforniaAges 18–75
Diabetes Mellitus trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting diabetes mellitus studies listed above.
- Ark Clinical Research · 4 studies
- Stanford University · 3 studies
- Catalina Research Institute · 2 studies
- Empire Clinical Research · 2 studies
- Hope Clinical Research · 2 studies
- Thrive Clinical Research Group · 2 studies
- University of California, San Francisco · 2 studies
- Acclaim Clinical Research
What taking part in a diabetes mellitus study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Diabetes Mellitus trials in other states
Common questions
- Are there diabetes mellitus clinical trials in California?
- Yes. We're currently tracking 76 recruiting diabetes mellitus studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a diabetes mellitus study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a diabetes mellitus trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New diabetes mellitus studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.