Clinical trials · California
Diabetes Mellitus clinical trials in California
We’re tracking 73 recruiting diabetes mellitus studies with a site in California — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT06783309RecruitingPhase 1/Phase 2
Testing CNP-103 for newly diagnosed type 1 diabetes
This trial tests a new study drug called CNP-103 for people ages 12-35 who were recently diagnosed (within 6 months) with stage 3 type 1 diabetes. The goal is to see if the drug can help preserve the body's ability to make some insulin, potentially slowing the need for more insulin shots.
Newport Beach, CaliforniaAges 12–35 - NCT07228117Recruiting
Testing a new automated insulin pump for people with diabetes
This study tests a new automated insulin delivery system (a pump that helps manage blood sugar) in children and adults with diabetes. It aims to see if the system is safe and easy to use in daily life.
Escondido, CaliforniaAges 7–85 - NCT07449039Recruiting
Blood sugar tracking after pregnancy for diabetes risk
This study uses a continuous glucose monitor to track blood sugar for 2 weeks after delivery in women who had gestational diabetes. The goal is to better understand who develops type 2 diabetes later and help prevent it.
Los Angeles, CaliforniaAges 18 years+ - NCT07590193RecruitingPhase 1
AMG 127 Safety Study in Healthy People and Type 2 Diabetes
This early-stage trial tests a new drug called AMG 127 to see if it's safe and how the body handles it. Researchers will enroll both healthy volunteers and people with type 2 diabetes to understand how the drug works in different groups.
Lake Forest, CaliforniaAges 18–75 - NCT07662213RecruitingPhase 3
Elecoglipron vs semaglutide for type 2 diabetes
This study tests an experimental diabetes pill (elecoglipron) to see if it works as well as a current medicine, semaglutide, for people with type 2 diabetes who also have heart risk factors. It aims to help better control blood sugar and weight.
Covina, CaliforniaAges 18 years+ - NCT06988306Recruiting
Lifestyle program to prevent diabetes after pregnancy
This study tests a lifestyle program (like diet and activity guidance) to help prevent diabetes after pregnancy in people who had gestational diabetes. You'll be part of a home visiting program and learn ways to stay healthy.
San Luis Obispo, CaliforniaAges 18 years+ - NCT07386340Recruiting
Testing a new continuous glucose monitor with flash readings
This study tests a new sensor system that tracks glucose levels continuously and can give a quick reading when you wave a device over it. It aims to see if it's safe and accurate for people with diabetes.
Escondido, CaliforniaAges 18 years+ - NCT07340320RecruitingPhase 2
CX11 tablets for type 2 diabetes
This trial tests an experimental drug called CX11 to see if it helps control blood sugar in people with type 2 diabetes who are already taking metformin. It may be an option for you if your blood sugar is not well controlled and you meet the health requirements.
Cerritos, CaliforniaAges 18–75 - NCT07662109RecruitingPhase 3
Testing a new combo pill for type 2 diabetes
This study tests if a new medicine (elecoglipron) combined with dapagliflozin is safe and works better for adults with type 2 diabetes that isn't well controlled by diet or other medications.
Bakersfield, CaliforniaAges 18 years+ - NCT07662044RecruitingPhase 3
Studying elecoglipron for type 2 diabetes
This trial tests a new medicine called elecoglipron, taken alone or with another diabetes drug (dapagliflozin), to see if it helps control blood sugar better than a placebo. It may be an option if your current treatment isn't working well enough.
Lomita, CaliforniaAges 18 years+ - NCT07579702Recruiting
Omnipod 6 Versus Omnipod 5 Insulin Pump System
This study compares two versions of the Omnipod insulin pump system to see if the newer Omnipod 6 works better at managing blood sugar than the current Omnipod 5. You'll wear one of these systems for several months and share data about how well it helps control your diabetes.
Los Angeles, CaliforniaAges 14–75 - NCT07465224RecruitingPhase 2
Study of ALN-4324 on Insulin Sensitivity in Type 2 Diabetes
This study tests an experimental drug, ALN-4324, to see if it can improve how your body responds to insulin. It’s for adults with type 2 diabetes who are already on certain diabetes medications and have stable blood sugar control.
Chula Vista, CaliforniaAges 18–65 - NCT05514184Enrolling by invitation
Diet coaching for diabetes and kidney disease to delay dialysis
This study tests a plant-focused diet plan to help people with diabetes and moderately to severely reduced kidney function avoid or delay needing dialysis. You would get diet instructions based on your random group and have several follow-up visits and check-ins over 6 months.
Torrance, CaliforniaAges 18 years+ - NCT07662135RecruitingPhase 3
A study of elecoglipron for type 2 diabetes with kidney problems
This trial tests a new medicine called elecoglipron to see if it helps control blood sugar in people with type 2 diabetes who also have reduced kidney function. You would continue taking your current SGLT2i medication (like dapagliflozin).
Concord, CaliforniaAges 18 years+ - NCT06329375Recruiting
Food Help for Diabetes Patients After Hospital Stay
This study helps people with diabetes who are admitted to Stanford Hospital and have trouble affording enough food. It provides meals through Mom's Meals after you go home, to make sure you have healthy food options.
Palo Alto, CaliforniaAges 18 years+ - NCT07606066Recruiting
Finding Type 2 Diabetes Patients for Future Research Studies
This is a screening study to identify and understand people with type 2 diabetes whose blood sugar isn't well controlled, so they can potentially join future diabetes research trials. You won't receive a new treatment in this study—it's about getting to know your health history and seeing if you might be a good fit for upcoming studies.
Lincoln, CaliforniaAges 18 years+ - NCT07176793Recruiting
Breastfeeding support after gestational diabetes
This study tests a breastfeeding support program for people who had gestational diabetes during pregnancy. The goal is to see if this support helps them breastfeed longer and stay healthy.
Sacramento, CaliforniaAges 18 years+ - NCT07664553RecruitingPhase 3
Testing a new diabetes tablet for people on insulin
This trial tests a new once-daily tablet (elecoglipron) against a placebo to see if it can help improve blood sugar control in adults with type 2 diabetes who are already on insulin. It may offer an additional treatment option to help manage your diabetes.
Sacramento, CaliforniaAges 18 years+ - NCT07355270Recruiting
Radiofrequency vapor ablation for type 2 diabetes
This trial tests a new device that uses radiofrequency energy to treat the lining of the upper small intestine in people with type 2 diabetes. The goal is to see if this treatment is safe and helps improve blood sugar control.
Newport Beach, CaliforniaAges 22–65 - NCT06657209RecruitingPhase 4
Comparing diabetes treatments for people with normal weight
This study tests two medications—pioglitazone (a pill) and tirzepatide (an injection)—in people with type 2 diabetes who have a normal body weight. It aims to find which treatment works better for this specific group.
Stanford, CaliforniaAges 30–70 - NCT06906653Enrolling by invitation
Proactive care for newly diagnosed type 2 diabetes
This trial tests a new, proactive approach to help people newly diagnosed with type 2 diabetes manage their condition through better initial care and support. If you’re a Kaiser Permanente Northern California member, you may get extra resources and guidance right from the start.
Pleasanton, CaliforniaAges 18–74 - NCT06836479Recruiting
Testing cultural meals for Asian Americans with type 2 diabetes
This study tests whether specially prepared meals that match your cultural background can help manage blood sugar levels. You'll wear a small sensor to track your glucose for 30 days and eat tailored meals for one week.
Stanford, CaliforniaAges 18 years+ - NCT07654374RecruitingPhase 3
Study of a new pill for weight loss and diabetes
This study tests a new daily pill (aleniglipron) to help adults with excess weight and type 2 diabetes lose weight and improve blood sugar control. It may be a good fit if you have a BMI of 27 or higher and your diabetes is managed with A1c between 6.5% and 10%.
Escondido, CaliforniaAges 18–79 - NCT03022682Recruiting
Study of inflammation and metabolism across diabetes and weight
This is an observational study that follows generally healthy adults to understand how inflammation, diabetes (type 2), and weight/metabolic health relate to each other. It may help researchers figure out why different groups (including different ethnic backgrounds) have different health risks.
San Francisco, CaliforniaAges 18–75
Diabetes Mellitus trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting diabetes mellitus studies listed above.
- Research Site · 7 studies
- Stanford University · 3 studies
- Diablo Clinical Research · 2 studies
- Headlands Research - AMCR Institute · 2 studies
- Hoag Memorial Hospital Presbyterian · 2 studies
- Rady Children's Hospital San Diego · 2 studies
- Sansum Diabetes Research Institute · 2 studies
- University of California, San Francisco · 2 studies
What taking part in a diabetes mellitus study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Diabetes Mellitus trials in other states
Common questions
- Are there diabetes mellitus clinical trials in California?
- Yes. We're currently tracking 73 recruiting diabetes mellitus studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a diabetes mellitus study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a diabetes mellitus trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New diabetes mellitus studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.