Clinical trials · Minnesota
Diabetes Mellitus clinical trials in Minnesota
We’re tracking 27 recruiting diabetes mellitus studies with a site in Minnesota — including Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Minnesota
- NCT06783309RecruitingPhase 1/Phase 2
Testing CNP-103 for newly diagnosed type 1 diabetes
This trial tests a new study drug called CNP-103 for people ages 12-35 who were recently diagnosed (within 6 months) with stage 3 type 1 diabetes. The goal is to see if the drug can help preserve the body's ability to make some insulin, potentially slowing the need for more insulin shots.
Minneapolis, MinnesotaAges 12–35 - NCT07228117Recruiting
Testing a new automated insulin pump for people with diabetes
This study tests a new automated insulin delivery system (a pump that helps manage blood sugar) in children and adults with diabetes. It aims to see if the system is safe and easy to use in daily life.
Minneapolis, MinnesotaAges 7–85 - NCT07662213RecruitingPhase 3
Elecoglipron vs semaglutide for type 2 diabetes
This study tests an experimental diabetes pill (elecoglipron) to see if it works as well as a current medicine, semaglutide, for people with type 2 diabetes who also have heart risk factors. It aims to help better control blood sugar and weight.
Minneapolis, MinnesotaAges 18 years+ - NCT07340320RecruitingPhase 2
CX11 tablets for type 2 diabetes
This trial tests an experimental drug called CX11 to see if it helps control blood sugar in people with type 2 diabetes who are already taking metformin. It may be an option for you if your blood sugar is not well controlled and you meet the health requirements.
Edina, MinnesotaAges 18–75 - NCT07579702Recruiting
Omnipod 6 Versus Omnipod 5 Insulin Pump System
This study compares two versions of the Omnipod insulin pump system to see if the newer Omnipod 6 works better at managing blood sugar than the current Omnipod 5. You'll wear one of these systems for several months and share data about how well it helps control your diabetes.
Minneapolis, MinnesotaAges 14–75 - NCT03865290RecruitingPhase 2
Ondansetron for stomach nerve and motion problems in diabetes
This trial tests whether ondansetron can improve stomach “sensorimotor” problems—how the gut senses food and moves it—especially in people with diabetes and troubling indigestion. It may help reduce symptoms like early fullness, nausea, and discomfort after eating.
Rochester, MinnesotaAges 18–75 - NCT07662135RecruitingPhase 3
A study of elecoglipron for type 2 diabetes with kidney problems
This trial tests a new medicine called elecoglipron to see if it helps control blood sugar in people with type 2 diabetes who also have reduced kidney function. You would continue taking your current SGLT2i medication (like dapagliflozin).
Saint Paul, MinnesotaAges 18 years+ - NCT06729996RecruitingPhase 2
Comparing two diabetes medicines for pancreatitis-related diabetes
This trial tests whether pioglitazone or empagliflozin is better at managing diabetes caused by chronic or recurrent pancreatitis. You will take one of these pills daily for 6 months and track your blood sugar and ketones at home. The goal is to find a safer, more effective treatment for this type of diabetes.
Rochester, MinnesotaAges 18–80 - NCT04210089Recruiting
Soft cast bandage for diabetic foot ulcers
This study tests whether a “total contact” soft cast bandage helps people heal diabetic foot ulcers. You may be asked to get your leg wrapped and have regular follow-up visits so the ulcer can be checked closely.
Minneapolis, MinnesotaAges 18 years+ - NCT07654374RecruitingPhase 3
Study of a new pill for weight loss and diabetes
This study tests a new daily pill (aleniglipron) to help adults with excess weight and type 2 diabetes lose weight and improve blood sugar control. It may be a good fit if you have a BMI of 27 or higher and your diabetes is managed with A1c between 6.5% and 10%.
Mankato, MinnesotaAges 18–79 - NCT03460769Recruiting
Mixed meal test to study diabetes from pancreas conditions
This study uses a special blood-sugar test (a mixed meal) to better diagnose and understand diabetes related to pancreatic cancer or chronic pancreatitis, and to compare it with other diabetes types. It may help researchers find clearer ways to tell these diabetes causes apart and understand how they work.
Minneapolis, MinnesotaAges 30–84 - NCT07076199RecruitingPhase 3
Weekly vs daily insulin for type 1 diabetes
This study tests a new once-weekly insulin (icodec) against a standard daily insulin (glargine), both taken with mealtime insulin. It aims to see which works better to control blood sugar in adults with type 1 diabetes.
Minneapolis, MinnesotaAges 18 years+ - NCT06957028Recruiting
CGM for early detection of high blood sugar in pregnancy
This study is testing whether wearing a continuous glucose monitor (CGM) early in pregnancy can help find and manage high blood sugar, which may lower the risk of problems for you and your baby. You would wear a small sensor under your skin, and the device sends information to a smartphone app.
Saint Louis Park, MinnesotaAges 18 years+ - NCT07088068RecruitingPhase 3
Teplizumab for newly diagnosed type 1 diabetes
This study tests whether teplizumab can help keep the body making insulin in people recently diagnosed with type 1 diabetes. It is for children and young adults aged 1 to 25, and compares the drug against a placebo.
Rochester, MinnesotaAges 1–25 - NCT07521475Recruiting
Fully Closed Loop Insulin Pump for Type 2 Diabetes
This study tests a new automated insulin pump system (Omnipod) that adjusts insulin doses on its own throughout the day for people with type 2 diabetes. The goal is to see if it helps keep blood sugar levels more stable while reducing the burden of manual insulin management.
Minneapolis, MinnesotaAges 18–75 - NCT07524205Recruiting
Activity and glucose tracking to reduce sitting in older adults with type 2 diabetes
This study helps older adults with type 2 diabetes understand how their blood sugar and daily activity are connected. You'll wear devices that track your glucose (blood sugar) and movement, and the research team will use this information to help you sit less and move more.
Minneapolis, MinnesotaAges 55 years+ - NCT07533175RecruitingPhase 3
Testing a new weight-loss medicine for type 2 diabetes
This study tests whether a new medicine called NNC0487-0111 helps people with type 2 diabetes and excess weight lose weight. You'll take the medicine along with your current diabetes care to see if it works better than standard treatment.
Minneapolis, MinnesotaAges 18 years+ - NCT02734277Recruiting
Extending a past Type 1 diabetes immune study
This study is for people who already took part in an earlier immune-tolerance program for Type 1 diabetes. It tests whether continuing follow-up and assessments can be done safely and may help learn more about long-term immune effects of treatment.
Minneapolis, MinnesotaAges 8–35 - NCT06730906Enrolling by invitation
PACTAID app for managing exercise in type 1 diabetes
This study tests an app called PACTAID that helps adults with type 1 diabetes manage their blood sugar during exercise. You will try three different types of workouts to see how well the app works.
Rochester, MinnesotaAges 18–65 - NCT07743450RecruitingPhase 3
Once-daily pill for weight loss in people with type 2 diabetes
This study tests an oral medication, ASC30, to see if it helps people with type 2 diabetes who are overweight or obese lose weight and improve blood sugar control. It is a once-daily pill that may offer a new treatment option.
Mankato, MinnesotaAges 18 years+ - NCT06906627Recruiting
Improving kidney screening for people with diabetes
This study helps people with type 2 diabetes get the right kidney tests to catch kidney problems early. Your doctor will check your kidney health through a simple blood and urine test.
Duluth, MinnesotaAges 18 years+ - NCT06906640Recruiting
Improving Kidney Care for People with Type 2 Diabetes
This study tests a program to help primary care doctors better screen and manage kidney problems in people with type 2 diabetes. It aims to see if using recommended medicines can slow kidney disease and improve health.
Duluth, MinnesotaAges 18 years+ - NCT05933161Recruiting
Testing diabetes blood-sugar tracking for people with an LVAD
This study looks at how well people with an LVAD can manage their blood sugar when they use a continuous glucose monitor app on a smartphone. It may help your diabetes care team adjust treatment using more complete sugar data.
Rochester, MinnesotaAges 18 years+ - NCT05980455Recruiting
Nighttime cycling of Enterra pacemaker for gastroparesis
This study tests a new way to program the Enterra stomach pacemaker so it cycles at night, aiming to improve gastroparesis symptoms. It's for people who already have the device and have stable symptoms.
Coon Rapids, MinnesotaAges 18–70
Where these studies are running in Minnesota
Institutions with a site for the recruiting diabetes mellitus studies listed above.
- Mayo Clinic · 8 studies
- University of Minnesota · 5 studies
- International Diabetes Center · 4 studies
- Research Site · 3 studies
- AES - DRS - Synexus Clinical Research US, Inc. - Edina - Minneapolis
- AURORA-2 Clinical Site
- Essentia Health Cancer Center
- Essentia Institute of Rural Health
What taking part in a diabetes mellitus study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Diabetes Mellitus trials in other states
Common questions
- Are there diabetes mellitus clinical trials in Minnesota?
- Yes. We're currently tracking 27 recruiting diabetes mellitus studies with a site in Minnesota, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a diabetes mellitus study in Minnesota?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Minnesota to take part?
- Not necessarily. These studies have a site in Minnesota, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a diabetes mellitus trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New diabetes mellitus studies open in Minnesota regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.