Clinical trials · California
Diabetes clinical trials in California
We’re tracking 189 recruiting diabetes studies with a site in California — including Early Phase 1, Phase 1/Phase 2, Phase 2 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT04460573RecruitingPhase 2
Using a smart boot to improve diabetic foot offloading
This trial studies whether a special “smart boot” can help people with diabetic foot ulcers rest (offload) the affected foot as they should. Better offloading may improve healing by reducing pressure on the wound.
Los Angeles, CaliforniaAges 18 years+ - NCT04684602RecruitingPhase 1/Phase 2
Study of stem cells for several short- and long-term illnesses
This early-stage study tests whether injections of mesenchymal stem cells can be safe and helpful for certain chronic (long-term) and acute (short-term) conditions. You might be considered if you can consent, are able to return for follow-up visits, and do not have key reasons that would make stem-cell treatment unsafe.
Culver City, CaliforniaAges 18 years+ - NCT04984226RecruitingPhase 2
Sodium bicarbonate for kidney disease energy and acidity
This trial studies whether taking sodium bicarbonate changes “energy” in cells and improves metabolic acidosis (an acid build-up) in people with moderate-to-severe chronic kidney disease. You may be able to join if your kidney function and blood bicarbonate levels fit their targets and you meet safety rules.
Sacramento, CaliforniaAges 21–85 - NCT05165706Recruiting
Study of how obesity affects insulin resistance over time
This study follows adults over time to understand how weight and body chemistry relate to insulin resistance. It may help researchers learn why insulin resistance happens and what could prevent or improve it.
Stanford, CaliforniaAges 35–65 - NCT05197920Recruiting
Study of diabetes after acute pancreatitis
This study looks at why some people develop diabetes after acute pancreatitis and how that process works in the body. It may help doctors better predict risk and tailor care for people recovering from pancreatitis.
Los Angeles, CaliforniaAges 18–75 - NCT05577390Recruiting
Comparing two treatments for diabetic nerve pain
This study compares two approaches to treating nerve pain caused by diabetes. You may be eligible if your diabetic neuropathy is moderate to severe and you can reliably use a phone for study steps.
Loma Linda, CaliforniaAges 45–85 - NCT05588583Recruiting
Tracking drainage from chronic leg or foot ulcers with a dressing
This study follows how much fluid (drainage) a chronic ulcer produces over time using a dressing called Mepilex Up. It may help clinicians better understand how this dressing manages “exuding” ulcers on the leg or foot.
Castro Valley, CaliforniaAges 18 years+ - NCT05589155Recruiting
Using a phone app to improve blood sugar and weight
This study looks at whether a mobile phone app can help people with type 2 diabetes improve their health habits, including blood sugar monitoring and weight. You may be able to join if you already check your blood sugar daily and are able to use a smartphone.
San Diego, CaliforniaAges 18–64 - NCT05708859RecruitingPhase 4
Tirzepatide to slow plaque buildup in coronary arteries
This trial studies tirzepatide to see if it can slow the progression of coronary artery plaque in people with type 2 diabetes. It uses special heart CT scans to track changes over time.
Torrance, CaliforniaAges 40–80 - NCT05832229RecruitingPhase 2
Studying rosuvastatin to slow liver scarring in cirrhosis
This Phase 2 trial tests whether rosuvastatin (a cholesterol-lowering medicine) can improve how well the liver functions and slow worsening scarring in people with cirrhosis. It also checks for side effects and safety.
San Francisco, CaliforniaAges 18–75 - NCT05986292RecruitingPhase 2
Study of new treatments for chronic pain
This study tests new treatments for chronic pain that lasts at least 3 months. Participants must stop their regular pain medicines and use only a rescue painkiller if needed. The goal is to find better ways to manage long-term pain.
Irvine, CaliforniaAges 18 years+ - NCT06120881RecruitingEarly Phase 1
Finding the Right Metformin Dose for Teens with Type 2 Diabetes
This study looks at how to give the right dose of metformin to young people with type 2 diabetes. If you join, you will wear a continuous glucose monitor for 6 weeks to help researchers find the best dose for you.
Oakland, CaliforniaAges 10–21 - NCT06322212RecruitingEarly Phase 1
Type 2 diabetes and brain blood barrier study
This study tests if a treatment can improve the blood-brain barrier in adults with type 2 diabetes. It uses MRI scans to see changes and may help protect brain function.
Los Angeles, CaliforniaAges 40–65 - NCT06325202Recruiting
A study on preventing low blood sugar with a closed loop system
This trial tests whether a closed-loop insulin pump combined with education can help people with type 1 diabetes better recognize and avoid dangerously low blood sugar. It may be a good fit if you've had diabetes for a long time and have trouble sensing when your blood sugar drops.
La Jolla, CaliforniaAges 18–75 - NCT06112418Recruiting
Personalized vs standard care to prevent heart attacks
This trial compares two ways to prevent heart attacks and strokes: one uses a special heart CT scan to guide care, the other uses standard risk factors like blood pressure and cholesterol. You may be eligible if you are older (men over 55, women over 65) and have diabetes, prediabetes, or metabolic syndrome.
Beverly Hills, CaliforniaAges 55 years+ - NCT05181826Recruiting
Blood collection study for cancer and benign diseases
This study collects blood samples from people with different health conditions (cancer, diabetes, liver disease, etc.) and from healthy volunteers. The goal is to find markers in the blood that could help detect or monitor diseases.
Redondo Beach, CaliforniaAges 18 years+ - NCT06401577Recruiting
Acute pancreatitis and diabetes risk study
This study looks at how acute pancreatitis affects blood sugar and the risk of developing diabetes. You'll wear a continuous glucose monitor (CGM) sensor and have metabolic tests to track changes over time.
Los Angeles, CaliforniaAges 18–75 - NCT06466135RecruitingPhase 2
Study of WAL0921 for glomerular kidney diseases
This study tests a new drug called WAL0921 for people with certain types of kidney disease. The goal is to see if it can help protect kidney function.
Los Angeles, CaliforniaAges 18–75 - NCT06515093Recruiting
New skin grafts for diabetic foot and venous leg ulcers
This study tests two new skin graft products (PelloGraft for diabetic foot ulcers and SanoGraft for venous leg ulcers) to see if they heal wounds faster than standard care. If you have a hard-to-heal foot or leg ulcer, this trial may offer a new option.
Vista, CaliforniaAges 18 years+ - NCT06516640Recruiting
CGM Education for Type 2 Diabetes
This trial helps teens and young adults with type 2 diabetes learn to use continuous glucose monitors (CGMs). It aims to make managing diabetes easier and more effective.
Los Angeles, CaliforniaAges 8–21 - NCT06598436Recruiting
Digital coaching for better diabetes or blood pressure control
This study offers a digital health coaching program to help people with poorly controlled diabetes or high blood pressure manage their condition. It works through telehealth tools and is designed for patients at San Francisco Health Network primary care clinics.
San Francisco, CaliforniaAges 18 years+ - NCT07354477RecruitingPhase 2
New eye drop for glaucoma and diabetic retinopathy
This trial tests a new eye drop (QLS-111) to see if it improves blood flow in the back of the eye. It may help people with mild to moderate glaucoma or stable diabetic retinopathy by reducing pressure inside the eye and nourishing the optic nerve.
Palo Alto, CaliforniaAges 18 years+ - NCT06724172Recruiting
Comparing health programs for pregnant mothers from diverse backgrounds
This study tests two different health programs for pregnant women to see which one helps mothers and babies more. You may join if you are early in your pregnancy, identify as Black, Hispanic, or have Medicaid, and speak English or Spanish.
Palo Alto, CaliforniaAges 18 years+ - NCT06891898Recruiting
The iLet Experience Study
This study is testing the iLet Bionic Pancreas System in people with type 1 diabetes. It looks at how well the system works in your daily life and asks you to share your glucose data and answer surveys.
Irvine, CaliforniaAges 6 years+
Diabetes trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting diabetes studies listed above.
- Stanford University · 5 studies
- University of Southern California · 3 studies
- Cedars-Sinai Medical Center · 2 studies
- Keck Medicine of USC · 2 studies
- The Lundquist Institute at Harbor-UCLA Medical Center · 2 studies
- University of California San Diego Health · 2 studies
- University of California, San Francisco · 2 studies
- Academic Medical Research Institute
What taking part in a diabetes study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Diabetes trials in other states
Common questions
- Are there diabetes clinical trials in California?
- Yes. We're currently tracking 189 recruiting diabetes studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a diabetes study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a diabetes trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New diabetes studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.