Clinical trials · Pennsylvania
Diabetes clinical trials in Pennsylvania
We’re tracking 97 recruiting diabetes studies with a site in Pennsylvania — including Phase 1, Phase 2, Phase 2/Phase 3, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Pennsylvania
- NCT07668388RecruitingPhase 2
Testing different doses of UBT251 for type 2 diabetes
This trial tests a new medicine, UBT251, to see how well it lowers blood sugar in people with type 2 diabetes. It compares different doses to find the best one for you.
Uniontown, PennsylvaniaAges 18–75 - NCT07654374RecruitingPhase 3
Study of a new pill for weight loss and diabetes
This study tests a new daily pill (aleniglipron) to help adults with excess weight and type 2 diabetes lose weight and improve blood sugar control. It may be a good fit if you have a BMI of 27 or higher and your diabetes is managed with A1c between 6.5% and 10%.
Philadelphia, PennsylvaniaAges 18–79 - NCT06419777Recruiting
When to start diabetes medicine in pregnancy
This study compares two ways of starting diabetes medication during pregnancy for women with gestational diabetes. It will test whether starting medication earlier or later helps control blood sugar and leads to better outcomes for you and your baby.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06419803Recruiting
When to start medication for gestational diabetes
This study compares two different blood sugar targets to decide when to start medication for gestational diabetes. It aims to find the safest approach for you and your baby.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07564414RecruitingPhase 3
Weight Loss Study Comparing Two Doses of CagriSema
This study tests whether a new combination medication called CagriSema (in two different doses) helps people with obesity lose weight. You may qualify if you're 18 or older, have a BMI of 35 or higher, and either don't have type 2 diabetes or have it well-controlled.
Beaver, PennsylvaniaAges 18 years+ - NCT07567833RecruitingPhase 4
Tracking Eye Function After Diabetes Swelling Treatment
This study follows patients with diabetic eye swelling (a complication of diabetes affecting the macula, the part of your eye needed for detailed vision) who are receiving anti-VEGF injections—a standard treatment that reduces abnormal blood vessel growth. Researchers will measure how well your retina (the light-sensitive tissue in your eye) recovers and functions over time.
Sewickley, PennsylvaniaAges 18 years+ - NCT07425522RecruitingPhase 1
Testing a new eye injection for diabetic macular edema
This study tests a new drug (RO7823653) given as an eye injection for people with diabetic macular edema, a condition where swelling in the retina harms vision. It aims to see if the drug is safe and how the body processes it.
Erie, PennsylvaniaAges 18 years+ - NCT07364630Recruiting
Placental membrane trial for diabetic and venous leg ulcers
This study tests whether a special wound dressing made from human placental membrane can help heal diabetic foot ulcers or venous leg ulcers that did not close with standard care. It is for people who were in the BIOCAMP trial and whose ulcer remained open after 12 weeks of standard treatment.
Philidelphia, PennsylvaniaAges 18 years+ - NCT07351058RecruitingPhase 3
Enicepatide for weight loss in people with type 2 diabetes
This trial tests an investigational medication, Enicepatide, to see if it helps people with obesity or overweight and type 2 diabetes lose weight and improve blood sugar control. You will receive weekly injections and regular check-ups.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07296484RecruitingPhase 2
Clofutriben for hard-to-control type 2 diabetes
This trial tests a new medication, clofutriben, for people with hard-to-control type 2 diabetes who might also have mild excess of a stress hormone called cortisol. It aims to see if the drug can help lower blood sugar and improve diabetes management.
West Chester, PennsylvaniaAges 18 years+ - NCT07285018RecruitingPhase 2
Study of a new drug for diabetic nerve pain in legs
This trial tests an investigational drug for people with pain caused by nerve damage from diabetes (diabetic peripheral neuropathy). It may help reduce pain in your lower legs if other treatments haven't worked well.
Duncansville, PennsylvaniaAges 18 years+ - NCT07282613RecruitingPhase 3
CagriSema for blood sugar and weight in children with type 2 diabetes
This study tests a new medicine called CagriSema to see if it can lower blood sugar and help with weight loss in children and teens with type 2 diabetes. It compares the medicine to a placebo (a look-alike with no active drug) over several months.
Philadelphia, PennsylvaniaAges 10–18 - NCT07271186RecruitingPhase 2
Study of an experimental drug for kidney disease from type 2 diabetes
This study tests an investigational drug called ALN-ANG3 to see if it can help people with diabetic kidney disease. The drug may reduce kidney damage and slow down the loss of kidney function. If you join, you will get the study drug or a placebo (a dummy shot) and be followed by a study doctor.
Bethlehem, PennsylvaniaAges 18–80 - NCT07270016Recruiting
Real-time support for young adults with type 2 diabetes
This trial tests an app designed to help young people manage their type 2 diabetes. It uses real-time feedback to improve blood sugar control and build healthy habits.
Pittsburgh, PennsylvaniaAges 16–24 - NCT07270133Recruiting
Diabetes eye health observation study
This study observes how diabetes affects vision over time in people with diabetes. It helps doctors better understand eye health without any treatment or intervention.
Sewickley, PennsylvaniaAges 18 years+ - NCT07222332RecruitingPhase 3
Baricitinib for new type 1 diabetes to save insulin-making cells
This trial tests if baricitinib, a pill that calms the immune system, can protect the remaining insulin-making cells in people newly diagnosed with type 1 diabetes. If it works, you might keep making some of your own insulin longer.
Philadelphia, PennsylvaniaAges 1–35 - NCT07222137RecruitingPhase 3
Baricitinib to delay type 1 diabetes in at-risk people
This trial tests if baricitinib, a pill that calms the immune system, can slow down or delay the onset of type 1 diabetes in children and adults who are at high risk. It is for people whose blood sugar is already starting to rise but who do not yet need insulin.
Philadelphia, PennsylvaniaAges 1–35 - NCT07187531RecruitingPhase 2
Testing a new drug to preserve insulin production in type 1 diabetes
This study tests a new drug called SAB-142, which aims to stop the immune system from attacking insulin-making cells in type 1 diabetes. It may help preserve your body's ability to make insulin. The trial will check if the drug is safe and effective.
Philadelphia, PennsylvaniaAges 5–40 - NCT07184775Recruiting
CGM vs finger-stick for type 2 diabetes in pregnancy
This trial tests if using a continuous glucose monitor (CGM) helps manage blood sugar better than finger-stick checks in pregnant women with type 2 diabetes. It aims to see if CGM leads to better sugar control and possibly healthier outcomes for you and your baby.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06535789RecruitingPhase 2/Phase 3
Inhaled insulin vs injections for gestational diabetes
This trial compares an inhaled insulin (Afrezza) to insulin injections for managing blood sugar after meals in women with gestational diabetes. The goal is to see if the inhaled option works as well and is easier to use.
Philadelphia, PennsylvaniaAges 18–40 - NCT07088068RecruitingPhase 3
Teplizumab for newly diagnosed type 1 diabetes
This study tests whether teplizumab can help keep the body making insulin in people recently diagnosed with type 1 diabetes. It is for children and young adults aged 1 to 25, and compares the drug against a placebo.
Philadelphia, PennsylvaniaAges 1–25 - NCT07064473RecruitingPhase 3
Testing vicadrostat plus empagliflozin for diabetes, high blood pressure, and heart disease
This study tests a new pill called vicadrostat taken with another medicine (empagliflozin) to see if it helps people with type 2 diabetes, high blood pressure, and heart disease. It may reduce the risk of heart problems, but you must not have had heart failure or use certain other heart medications.
Beaver, PennsylvaniaAges 18 years+ - NCT06957028Recruiting
CGM for early detection of high blood sugar in pregnancy
This study is testing whether wearing a continuous glucose monitor (CGM) early in pregnancy can help find and manage high blood sugar, which may lower the risk of problems for you and your baby. You would wear a small sensor under your skin, and the device sends information to a smartphone app.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06938685Recruiting
Testing a new wound treatment for diabetic foot ulcers
This trial tests a new wound covering called NeoThelium FT to help diabetic foot ulcers heal. It is for people whose ulcer has not improved much with standard care and is not infected or too deep.
Bryn Mawr, PennsylvaniaAges 18 years+
Diabetes trials by city in Pennsylvania
Where these studies are running in Pennsylvania
Institutions with a site for the recruiting diabetes studies listed above.
- Children's Hospital of Philadelphia · 4 studies
- Thomas Jefferson University · 4 studies
- Suburban Research Associates · 3 studies
- Pittsburgh Clinical Trial Consortium · 2 studies
- Preferred Primary Care Physicians · 2 studies
- Retina-Vitreous Consultants, Inc. · 2 studies
- University of Pennsylvania · 2 studies
- ACCOMPLISH-2 Research Site
What taking part in a diabetes study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Diabetes trials in other states
Common questions
- Are there diabetes clinical trials in Pennsylvania?
- Yes. We're currently tracking 97 recruiting diabetes studies with a site in Pennsylvania, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a diabetes study in Pennsylvania?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Pennsylvania to take part?
- Not necessarily. These studies have a site in Pennsylvania, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a diabetes trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New diabetes studies open in Pennsylvania regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.