Clinical trials · Pennsylvania
Diabetes clinical trials in Pennsylvania
We’re tracking 98 recruiting diabetes studies with a site in Pennsylvania — including Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Pennsylvania
- NCT07425522RecruitingPhase 1
Testing a new eye injection for diabetic macular edema
This study tests a new drug (RO7823653) given as an eye injection for people with diabetic macular edema, a condition where swelling in the retina harms vision. It aims to see if the drug is safe and how the body processes it.
Erie, PennsylvaniaAges 18 years+ - NCT07088068RecruitingPhase 3
Teplizumab for newly diagnosed type 1 diabetes
This study tests whether teplizumab can help keep the body making insulin in people recently diagnosed with type 1 diabetes. It is for children and young adults aged 1 to 25, and compares the drug against a placebo.
Philadelphia, PennsylvaniaAges 1–25 - NCT07654374RecruitingPhase 3
Study of a new pill for weight loss and diabetes
This study tests a new daily pill (aleniglipron) to help adults with excess weight and type 2 diabetes lose weight and improve blood sugar control. It may be a good fit if you have a BMI of 27 or higher and your diabetes is managed with A1c between 6.5% and 10%.
Philadelphia, PennsylvaniaAges 18–79 - NCT07668388RecruitingPhase 2
Testing different doses of UBT251 for type 2 diabetes
This trial tests a new medicine, UBT251, to see how well it lowers blood sugar in people with type 2 diabetes. It compares different doses to find the best one for you.
Uniontown, PennsylvaniaAges 18–75 - NCT07271186RecruitingPhase 2
Study of a New Drug for Diabetic Kidney Disease
This study tests an investigational drug that blocks a protein called ANGPTL3, which may help protect the kidneys in people with type 2 diabetes and diabetic kidney disease. It aims to see if the drug can reduce kidney damage and improve overall health.
Bethlehem, PennsylvaniaAges 18–80 - NCT07222137RecruitingPhase 3
Baricitinib to delay type 1 diabetes in at-risk people
This trial tests if baricitinib, a pill that calms the immune system, can slow down or delay the onset of type 1 diabetes in children and adults who are at high risk. It is for people whose blood sugar is already starting to rise but who do not yet need insulin.
Philadelphia, PennsylvaniaAges 1–35 - NCT07222332RecruitingPhase 3
Baricitinib for new type 1 diabetes to save insulin-making cells
This trial tests if baricitinib, a pill that calms the immune system, can protect the remaining insulin-making cells in people newly diagnosed with type 1 diabetes. If it works, you might keep making some of your own insulin longer.
Philadelphia, PennsylvaniaAges 1–35 - NCT05390892RecruitingPhase 4
Preventing kidney and heart damage in type 2 diabetes
This study tests whether diabetes medicines can help prevent worsening heart and kidney problems in people with type 2 diabetes. You’ll be assigned by chance to one of these medicine types, and your other care will be adjusted for safety.
Philadelphia, PennsylvaniaAges 40–80 - NCT06957028Recruiting
CGM for early detection of high blood sugar in pregnancy
This study is testing whether wearing a continuous glucose monitor (CGM) early in pregnancy can help find and manage high blood sugar, which may lower the risk of problems for you and your baby. You would wear a small sensor under your skin, and the device sends information to a smartphone app.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06628908RecruitingPhase 3
Study of suzetrigine for painful diabetic nerve damage
This trial tests an experimental medicine called suzetrigine to see if it can safely reduce pain caused by nerve damage from diabetes (diabetic peripheral neuropathy). It might be an option if you have had daily pain in both legs and current treatments haven't worked well enough.
Media, PennsylvaniaAges 18–80 - NCT07449936RecruitingPhase 3
Comparing a new long-lasting injection to standard one for DME
This phase 3 trial tests a new long-acting injection (EYP-1901) against a standard one (aflibercept) for people with diabetic macular edema. Both treatments are given as eye injections, and the goal is to see if the new drug works as well and may require fewer injections.
Erie, PennsylvaniaAges 18 years+ - NCT07449923RecruitingPhase 3
Comparing a new injection to standard treatment for diabetic macular edema
This trial compares a new treatment (EYP-1901, given as an injection) to a standard injection (aflibercept) for people with diabetic macular edema. It aims to see which works better at reducing swelling and improving vision.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07285018RecruitingPhase 2
Study of a new drug for diabetic nerve pain in legs
This trial tests an investigational drug for people with pain caused by nerve damage from diabetes (diabetic peripheral neuropathy). It may help reduce pain in your lower legs if other treatments haven't worked well.
Duncansville, PennsylvaniaAges 18 years+ - NCT05296447Enrolling by invitationPhase 2
Long-term safety study for diabetic retinopathy gene therapy
This study follows people who already received an injection of RGX-314 (an experimental gene therapy) in a previous clinical trial for diabetic retinopathy, with or without swelling in the macula. It checks the long-term safety and how the treatment works over time.
Philadelphia, PennsylvaniaAges Any age - NCT06729996RecruitingPhase 2
Comparing two diabetes medicines for pancreatitis-related diabetes
This trial tests whether pioglitazone or empagliflozin is better at managing diabetes caused by chronic or recurrent pancreatitis. You will take one of these pills daily for 6 months and track your blood sugar and ketones at home. The goal is to find a safer, more effective treatment for this type of diabetes.
Pittsburgh, PennsylvaniaAges 18–80 - NCT03460769Recruiting
Mixed meal test to study diabetes from pancreas conditions
This study uses a special blood-sugar test (a mixed meal) to better diagnose and understand diabetes related to pancreatic cancer or chronic pancreatitis, and to compare it with other diabetes types. It may help researchers find clearer ways to tell these diabetes causes apart and understand how they work.
Pittsburgh, PennsylvaniaAges 30–84 - NCT04024631Recruiting
Study genes and diabetes risk using body measurements
This study looks at how genetic risk relates to developing type 2 diabetes, using information from a biobank and body measurements like weight. It may help researchers better identify who is at higher risk before diabetes starts.
Philadelphia, PennsylvaniaAges 10–70 - NCT04786262RecruitingPhase 3
Study of VX-880 for long-standing type 1 diabetes
This Phase 3 trial tests how safe, tolerable, and effective VX-880 is for people with type 1 diabetes who have had it for many years. It may help reduce problems related to blood sugar swings, especially severe low blood sugar episodes.
Philadelphia, PennsylvaniaAges 18–65 - NCT05124808Recruiting
Tight blood sugar targets in pregnant women with gestational diabetes
This study compares a tighter blood sugar goal versus a standard goal in pregnant people with gestational diabetes who are also overweight or obese. It may help find whether stricter blood sugar control improves pregnancy outcomes.
Pittsburgh, PennsylvaniaAges 18–45 - NCT05482789RecruitingPhase 4
Exenatide study in pregnancy-related diabetes without medicines
This trial studies how exenatide affects blood sugar in pregnant people with gestational diabetes who do not need medication yet. The goal is to understand how the medicine works in the body during pregnancy, which may help improve future treatment decisions.
Pittsburgh, PennsylvaniaAges 18–50 - NCT05758545Recruiting
Device treatment for diabetic foot ulcers with poor blood flow
This trial tests whether COMS One is safe and effective for healing a specific diabetic foot ulcer. It may help people whose ulcer is not healing well, especially when blood flow to the foot is limited.
McKeesport, PennsylvaniaAges 22–90 - NCT05846802Recruiting
Gastroparesis and stomach symptoms registry for adults
This registry is for adults with long-lasting stomach emptying problems or related symptoms, helping researchers better understand patterns of nausea, pain, and fullness. You may be able to join if you meet specific symptom and test results, and can complete a stomach-emptying scan.
Philadelphia, PennsylvaniaAges 18–85 - NCT06107816Recruiting
Fruit and vegetable prescription for diabetes
This trial provides a fruit and vegetable prescription to help people with type 2 diabetes improve their blood sugar control. It is designed for adults who have had diabetes for at least six months, have elevated A1c levels (7% or higher), and meet low-income criteria.
Reading, PennsylvaniaAges 18 years+ - NCT06264258Recruiting
Game-based diabetes education for kids
This study tests a fun video game to help children aged 6–12 with type 1 diabetes learn about managing their condition. It may improve how kids check their blood sugar and take insulin.
Pittsburgh, PennsylvaniaAges 6–12
Diabetes trials by city in Pennsylvania
Where these studies are running in Pennsylvania
Institutions with a site for the recruiting diabetes studies listed above.
- Children's Hospital of Philadelphia · 4 studies
- University of Pennsylvania · 3 studies
- University of Pittsburgh Medical Center · 3 studies
- Wills Eye Hospital · 3 studies
- Erie Retina Research · 2 studies
- Suburban Research Associates · 2 studies
- Temple University Hospital · 2 studies
- University of Pittsburgh · 2 studies
What taking part in a diabetes study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Diabetes trials in other states
Common questions
- Are there diabetes clinical trials in Pennsylvania?
- Yes. We're currently tracking 98 recruiting diabetes studies with a site in Pennsylvania, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a diabetes study in Pennsylvania?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Pennsylvania to take part?
- Not necessarily. These studies have a site in Pennsylvania, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a diabetes trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New diabetes studies open in Pennsylvania regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.