Clinical trials
Diabetic Peripheral Neuropathy clinical trials
Below are recruiting diabetic peripheral neuropathy clinical trials, each written for real people, not researchers. We’re tracking 116 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06124586Recruiting
Early angioplasty for diabetic foot ulcers
This trial tests if an early procedure to open blocked leg arteries (angioplasty) helps heal foot ulcers in people with type 2 diabetes. It aims to improve blood flow and prevent amputation.
DüsseldorfAges 18 years+ - NCT05577390Recruiting
Comparing two treatments for diabetic nerve pain
This study compares two approaches to treating nerve pain caused by diabetes. You may be eligible if your diabetic neuropathy is moderate to severe and you can reliably use a phone for study steps.
Loma Linda, CaliforniaAges 45–85 - NCT05950659Recruiting
Wearable insoles to prevent repeat diabetic foot ulcers
This trial tests special sensory insoles (called Orpyx Sensory Insoles) to help prevent diabetic foot ulcers from coming back. It aims to reduce high-pressure foot spots for people who already had a healed nerve-related ulcer.
Baltimore, MarylandAges 18 years+ - NCT05965336Recruiting
Walking test study for nerve damage in diabetes feet
This study looks at how well people with diabetes-related nerve damage (diabetic peripheral neuropathy) can walk, using a treadmill and walking distance tests. It may help improve understanding of walking limits and how to measure change over time.
Pensacola, FloridaAges 45 years+ - NCT03481283Recruiting
Testing amylin’s role in nerve pain from type 2 diabetes
This study looks at whether amylin is involved in nerve damage causing pain or numbness in the feet or hands for people with type 2 diabetes. If you qualify, you may be evaluated with nerve testing to see how your nerve function compares to the study’s targets.
Lexington, KentuckyAges 18 years+ - NCT07405021Recruiting
Vagus nerve stimulation for diabetic nerve pain
This trial tests whether using a non-invasive device to stimulate the vagus nerve can reduce nerve pain and improve function in people with diabetic neuropathy. It may be a good option if you have burning or electric-shock-like foot pain despite standard diabetes care.
DamiettaAges 45–60 - NCT07859111RecruitingPhase 3
YJ001 spray for diabetic nerve pain in the feet
This trial tests a spray called YJ001 for pain in the feet caused by diabetic nerve damage. It aims to see if the spray can reduce pain better than a placebo, and may offer a new way to manage this type of pain.
Beijing, Haidian DistrictAges 18 years+ - NCT07451431RecruitingPhase 4
Mirogabalin for diabetic nerve pain study
This study tests a new pain medicine called Mirogabalin for people with diabetic nerve pain that hasn't gotten better with usual treatments. It aims to see how well the drug works and if it is safe.
DhakaAges 40 years+ - NCT07377721RecruitingPhase 1
Study of HRS-2129 for diabetic nerve pain
This trial tests a new medicine called HRS-2129 for people with long-term nerve pain caused by diabetes. It aims to see if the drug can safely reduce pain.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07315334Recruiting
Understanding nerve damage from chemotherapy
This study looks at how chemotherapy-related nerve damage affects daily activities like walking and standing. It includes people who currently have or have had nerve-damaging chemotherapy and are experiencing nerve pain or weakness.
SalzburgAges 18 years+ - NCT07304401Recruiting
Closed-loop spinal cord stimulation for chemo-related nerve pain
This trial tests whether a new type of spinal cord stimulator (SCS) can reduce pain caused by chemotherapy. If you have lasting nerve pain after cancer treatment and standard pain medications haven't helped, this device might offer relief.
ArnhemAges 18 years+ - NCT07285018RecruitingPhase 2
Study of a new drug for diabetic nerve pain in legs
This trial tests an investigational drug for people with pain caused by nerve damage from diabetes (diabetic peripheral neuropathy). It may help reduce pain in your lower legs if other treatments haven't worked well.
Birmingham, AlabamaAges 18 years+ - NCT07122726Recruiting
Balance exercises for fall prevention in diabetes
This study tests whether adding special movement exercises (called proprioceptive neuromuscular facilitation) to standard Otago exercises can help improve balance and reduce the risk of falls in people with type 2 diabetes who have nerve damage in their feet.
IslamabadAges 50–75 - NCT06706544RecruitingPhase 2/Phase 3
Ozone treatment for numbness or tingling after chemo
This trial tests whether ozone treatment (a gas therapy) can help relieve numbness or tingling caused by chemotherapy. It is for people whose cancer is stable or in remission and who have had these nerve symptoms for at least 3 months.
Las Palmas, Las PalmasAges 18 years+ - NCT05483816Recruiting
Sensory stimulation trial for nerve pain in people with neuropathy
This study tests a multi-sensory (multiple-sense) stimulation approach to see if it can help people with nerve-related pain in the legs/feet. You must be able to safely take part in MRI-related sessions and answer questions about pain and health history.
Zurich, Canton of ZurichAges 18–80 - NCT06763575Recruiting
Surgical glove compression to prevent nerve damage from paclitaxel
This trial tests if wearing surgical gloves that compress the hands can prevent nerve damage caused by the chemotherapy drug paclitaxel. If you have a solid tumor and are getting paclitaxel every 3 weeks, this might help reduce numbness, tingling, or pain in your hands.
Bangkok, BangkokAges 18 years+ - NCT06430814Recruiting
Blood test to predict nerve damage from paclitaxel
This study looks at whether certain markers in your blood can predict nerve damage from paclitaxel chemotherapy. If you join, researchers will monitor your nerve health during treatment to better understand and possibly prevent side effects.
OdenseAges 18 years+ - NCT05840562RecruitingPhase 3
Capsaicin skin patch vs duloxetine for nerve pain after chemo
This Phase 3 trial tests whether a capsaicin patch works better than duloxetine tablets to reduce painful nerve pain after chemotherapy. It aims to help people whose “gloves and socks” nerve pain has lasted after chemo.
AngersAges 18 years+ - NCT04763356Recruiting
Remote monitoring to manage nerve pain after chemotherapy
This study tests whether remote check-ins (via phone/app/website) can help manage chemotherapy-related nerve pain in the hands and feet. It enrolls adults who developed nerve symptoms after certain cancer medicines and need ongoing monitoring.
Salt Lake City, UtahAges 18 years+ - NCT07714278Enrolling by invitation
Video-based rehab for chemotherapy nerve damage
This study tests a personalized rehab program using video analysis to help people with chemotherapy-induced nerve damage (numbness, tingling, weakness) improve their walking and daily life.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT07481149RecruitingPhase 3
Virtual exercise program for chemo nerve damage
This study tests a virtual exercise program to help people with nerve pain or numbness after chemotherapy. It is designed for anyone who finished chemo at least 6 months ago and still has symptoms in their hands or feet.
Toronto, OntarioAges 18 years+ - NCT06914557RecruitingPhase 2
Scrambler therapy plus duloxetine for chemo nerve pain
This study tests whether adding a non-invasive device called Scrambler Therapy to the usual nerve pain medicine (duloxetine) can better relieve chemotherapy-induced nerve pain. It is for people with cancer who still have significant nerve pain despite taking duloxetine.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07009717Recruiting
Big toe strength and chemo nerve damage
This study looks at whether the strength of your big toe is related to nerve damage from chemotherapy. It involves a one-time test of your toe strength and some questionnaires. It may help researchers better understand how chemo affects your nerves.
Gainesville, FloridaAges 18–90 - NCT07131410Enrolling by invitation
Hyaluronic acid cream to prevent foot ulcers in diabetes
This trial tests a cream made with hyaluronic acid, a natural substance that helps keep skin moist, to see if it can prevent foot sores in people with type 2 diabetes and nerve damage in their feet. If you have diabetes-related nerve issues and want to protect your feet, this study may be for you.
MálagaAges 18 years+
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Common questions
- Are there clinical trials for diabetic peripheral neuropathy?
- Yes. Clin2 currently lists 116 recruiting diabetic peripheral neuropathy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a diabetic peripheral neuropathy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a diabetic peripheral neuropathy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.