Clinical trials
Diuretics clinical trials
Below are recruiting diuretics clinical trials, each written for real people, not researchers. We’re tracking 32 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07369856Recruiting
Using urine sodium to guide diuretic dosing in heart failure
This trial uses a simple urine test to see if your current water pill dose is right for you. The goal is to find the best dose to reduce symptoms and avoid hospital visits.
Vancouver, British ColumbiaAges 18 years+ - NCT07348510Recruiting
Diuretic Effect of Aminophylline and Furosemide in Heart Surgery Patients
This study is testing if a combination of two medicines (aminophylline and furosemide) can help the kidneys produce more urine after heart surgery. It may help reduce fluid buildup and protect kidney function.
CairoAges 18–65 - NCT07320677Enrolling by invitation
Finding Heart Failure in People Taking Water Pills
This study is for people who take a type of water pill called a loop diuretic, but do not yet have a diagnosis of heart failure. The study will check a blood test to see if undiagnosed heart failure might be present.
Saint HelierAges 18 years+ - NCT06921603Recruiting
Ultrasound-guided diuretics for heart failure
This trial tests whether using a bedside ultrasound to guide diuretic treatment improves outcomes in people hospitalized for worsening heart failure. It may help find the right dose of IV diuretics faster.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06841692Recruiting
Diuretic testing for moderate kidney disease
This study checks how well diuretics (water pills) work in people with moderate chronic kidney disease. It may help doctors understand how to better treat fluid buildup in patients.
Rotterdam, South HollandAges 18 years+ - NCT04759274Recruiting
Personalized water pill dosing support for kidney and fluid overload
This trial tests a decision-support tool to help your care team safely adjust water pills (“diuretics”) when you have kidney disease and fluid buildup. It may help reduce swelling by guiding dosing using your home weight and blood pressure.
Dallas, TexasAges 18 years+ - NCT06209359RecruitingPhase 1
Testing a second diuretic for heart failure patients
This trial tests whether adding a second type of diuretic (water pill) can help people with heart failure who don't respond well to their current diuretic. It aims to find better ways to manage fluid buildup.
New Haven, ConnecticutAges 18 years+ - NCT06092437Recruiting
Testing a personalized diuretic plan for acute heart failure
This trial is testing whether a diuretic (water pill) dose tailored to each patient works better for treating fluid buildup during a heart failure flare-up. It may help you get the right amount of medication faster and avoid complications.
Heerlen, LimburgAges 18 years+ - NCT02812212Recruiting
Test a kidney scan to spot early blockage in newborns
This study checks whether a specific kidney test (a renogram scan) can detect a significant urine blockage early in babies born with ureter-pelvic junction obstruction (a narrow connection between the kidney and ureter). It may help clinicians decide sooner which babies need closer follow-up or treatment.
BordeauxAges 4 weeks–2 months - NCT05620784RecruitingPhase 3
Loop water pills during surgery to go home sooner after HoLEP
This trial tests whether giving a “loop diuretic” water pill during surgery can help people after HoLEP go home the same day more often. It’s mainly looking to improve discharge timing while keeping you safe.
Chicago, IllinoisAges 18–89 - NCT06218199RecruitingPhase 4
Diuretics vs. blood pressure meds for HeartLogic alerts
This trial compares two treatments—diuretics (water pills) and a blood pressure medication called sacubitril/valsartan—to see which works better when your heart device sends an alert. It's for people with a Boston Scientific heart device that has HeartLogic alerting turned on.
Huntsville, AlabamaAges 19 years+ - NCT07726134Recruiting
Diuretic use during kidney transplant to help the new kidney work faster
This trial tests whether giving a diuretic (a medication that helps flush fluids) during kidney transplant surgery helps a deceased-donor kidney start working sooner after the procedure.
London, OntarioAges 18 years+ - NCT06630923RecruitingPhase 3
Preventing kidney worsening with IV albumin in heart failure
This trial tests if giving a medicine called albumin through a vein can help prevent kidney function from getting worse in people hospitalized with worsening heart failure and liver problems. It may be an option if other treatments haven't worked.
Alexandroupoli, EvrosAges 18–95 - NCT07577596RecruitingPhase 4
Continuous Furosemide Infusion for Heart Failure Fluid Overload
This study tests whether giving furosemide (a water pill) as a continuous IV drip works better than standard doses for patients hospitalized with heart failure and fluid buildup. The goal is to help your body get rid of excess fluid more effectively.
RandersAges 18 years+ - NCT06750575Recruiting
Study of furosemide on toxin removal in chronic kidney disease
This study tests whether the water pill furosemide can help remove certain toxins from the blood in people with chronic kidney disease (CKD stages 3-5) who are starting this medicine as part of their regular care.
Utrecht, UtrechtAges 18 years+ - NCT06799910Recruiting
Optimizing fluid balance with bioelectrical impedance during dialysis in ICU
This trial tests a method to better manage fluid levels in critically ill patients who are receiving a type of dialysis (CVVH) for kidney failure. It uses a device (bioelectrical impedance) to measure fluid in the body, which may help doctors give the right amount of fluids more safely.
SalouëlAges 18 years+ - NCT07417969Recruiting
Albumin with furosemide for fluid overload in ICU
This study tests whether giving a medicine called albumin together with a water pill (furosemide) helps ICU patients who have too much fluid in their body and are making very little urine. The goal is to see if this combination can improve urine output and protect kidney function.
Querétaro City, QuerétaroAges 18–100 - NCT07372040RecruitingPhase 2
Adding a Water Pill for Heart Failure in the Hospital
This trial tests if adding a diuretic (water pill) called acetazolamide to usual care can help you get rid of extra fluid faster while you are in the hospital for worsening heart failure.
TantaAges 18 years+ - NCT07281040Recruiting
Online discussion about heart failure treatment experiences
This study brings together people who have recently been in the hospital for heart failure and their caregivers to talk in small online groups about their experiences. The goal is to help doctors learn what matters most to patients and to plan better research on heart failure treatments.
Hull, YorkshireAges 18 years+ - NCT07271420RecruitingPhase 4
Blood pressure drug study for dialysis patients
This trial tests whether a common blood pressure medication (thiazide diuretics) helps control high blood pressure in people on peritoneal dialysis. The goal is to see if it can lower blood pressure and improve health.
Hong KongAges 18 years+ - NCT07263035RecruitingPhase 4
Urine sodium-guided diuretic strategy for heart failure
This trial tests a new way to adjust diuretic (water pill) doses based on urine sodium levels in patients hospitalized for worsening heart failure. The goal is to improve fluid removal and get patients home sooner.
Lakeland, FloridaAges 18 years+ - NCT07022314Recruiting
Monitoring urine output in cardiac ICU patients
This trial tests a new device that tracks urine output after heart surgery to see how the body responds to fluids and diuretics. It may help doctors manage your recovery more closely.
Petah TikvaAges 18 years+ - NCT04934228RecruitingPhase 1
Study targeting inflammation in people with obesity and high blood pressure
This Phase 1 study looks at a treatment aimed at reducing “inflammation patterns” that are common in obesity and insulin resistance. If you meet specific health and lab criteria, you may be asked to visit a research lab and provide blood samples to see how the treatment affects your body.
Kansas City, KansasAges 18–79 - NCT02638142Recruiting
Testing IV diuretic treatment for sudden worsening heart failure
This trial studies how an IV (into-the-vein) “water pill” (furosemide/loop diuretic) works in people whose heart failure has suddenly gotten worse. It may help doctors find the best way to reduce fluid-related symptoms like breathing trouble and swelling.
Chioggia, VeneziaAges 18 years+
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Common questions
- Are there clinical trials for diuretics?
- Yes. Clin2 currently lists 32 recruiting diuretics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a diuretics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a diuretics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.