Clinical trials · Detroit, MI
Down Syndrome clinical trials in Detroit
We’re tracking 80 recruiting down syndrome studies with a site in or near Detroit — including Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Detroit
- NCT00358943Recruiting
Gaucher disease registry and pregnancy tracking study
This study creates a large, long-term record of people with Gaucher disease and details about pregnancy outcomes. It helps researchers better understand Gaucher over a person’s life and during pregnancy.
Detroit, MichiganAges Any age - NCT01429389Recruiting
Testing genetic samples in pregnancy to check chromosome changes
This study collects genetic samples from pregnant people who have a higher chance of chromosome changes in the baby. It tests whether taking samples through CVS and/or amniocentesis can help understand the baby’s genetic makeup.
Detroit, MichiganAges 18 years+ - NCT02074839RecruitingPhase 1
Oral AG-120 for advanced blood cancers with an IDH1 mutation
This Phase 1 study tests an oral medicine called AG-120 in adults with advanced blood cancers that have a specific IDH1 mutation. It also looks at safety and how the treatment works, with frequent blood, urine, and bone marrow samples.
Detroit, MichiganAges 18 years+ - NCT04179981Recruiting
CPAP treatment effects in older COPD and sleep apnea patients
This study looks at whether using positive airway pressure (often called CPAP) improves health outcomes in older adults who have both COPD and obstructive sleep apnea. It may help find ways to reduce symptoms and complications from “overlap” breathing problems.
Detroit, MichiganAges 60 years+ - NCT05564390RecruitingPhase 2
MyeloMATCH screening to match you to AML or MDS treatment
This study screens people with newly suspected acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) to see which treatment approach fits best—either a specific study treatment or standard care. It may help by directing you to the right option and by sharing your blood/bone marrow samples for research.
Detroit, MichiganAges 18 years+ - NCT04546399RecruitingPhase 2
Blinatumomab with or without nivolumab for first relapse ALL
This study compares blinatumomab alone versus blinatumomab plus nivolumab in young people whose B-cell ALL has returned for the first time. It aims to see whether adding nivolumab improves control of the leukemia after relapse.
Detroit, MichiganAges 1–30 - NCT06701669RecruitingPhase 2
Study of Paridiprubart for moderate to severe ARDS
This trial tests a new medicine called paridiprubart to see if it can help people with moderate or severe acute respiratory distress syndrome (ARDS), a serious lung condition. It may be an option if you have low oxygen levels and no known allergy to the drug.
Detroit, MichiganAges 18 years+ - NCT07087054RecruitingPhase 3
A daily pill for carcinoid syndrome symptoms
This trial tests an oral daily medication, paltusotine, to reduce flushing and other symptoms of carcinoid syndrome in people with neuroendocrine tumors. It may be an option for those who need treatment and have stable disease.
Detroit, MichiganAges 18 years+ - NCT03816345RecruitingPhase 1
Nivolumab for advanced cancer with autoimmune conditions
This Phase 1 study tests nivolumab, an immunotherapy “anti-cancer accelerator,” in people with advanced cancer who also have an autoimmune disorder. It aims to see if nivolumab can be given safely and whether it may help shrink or control cancer.
Detroit, MichiganAges 18 years+ - NCT02703207Recruiting
Sleep apnea and COPD effects in older veterans
This study looks at how sleep apnea affects thinking skills and overall health in older veterans who also have COPD. It may help researchers understand what changes to target to improve daytime functioning and wellbeing.
Detroit, MichiganAges 60–89 - NCT06701656RecruitingPhase 2
Testing bevacizumab for breathing problems from ARDS
This trial tests if bevacizumab can help people with ARDS (a serious lung condition) breathe better. It is for patients with mild, moderate, or severe ARDS who are already in the hospital.
Detroit, MichiganAges 18 years+ - NCT07020819RecruitingPhase 3
Study of tanruprubart for people with Guillain-Barré syndrome
This trial tests a new medicine, tanruprubart (also called ANX005), for people with Guillain-Barré syndrome. It aims to see if the drug can help improve recovery when given soon after symptoms start.
Detroit, MichiganAges 12–85 - NCT06859424RecruitingPhase 2
Testing a new GVHD prevention method after donor stem cell transplant
This trial tests a new way to prevent graft-versus-host disease (a common side effect of stem cell transplant) using a drug called cyclophosphamide after transplant. It is for adults with certain blood cancers who need a transplant from a partially matched unrelated donor.
Detroit, MichiganAges 18–66 - NCT05509933RecruitingPhase 3
Budesonide to prevent engraftment syndrome after stem cell transplant
This Phase 3 study tests whether budesonide can prevent “engraftment syndrome” after people receive a hematopoietic (blood-forming) stem cell transplant. If it works, it may reduce complications around the time the new cells start growing and making blood cells.
Detroit, MichiganAges 18–80 - NCT05677100Recruiting
Aortix device for acute heart failure
This trial is testing a small pump placed in the aorta to help the kidneys remove extra fluid when standard IV diuretics aren't working well enough for severe heart failure. It may help you if you're hospitalized and still very congested (swollen, fluid buildup) despite strong water pills.
Detroit, MichiganAges 21 years+ - NCT04064060RecruitingPhase 3
Long-term safety follow-up for luspatercept study participants
This trial studies the long-term safety of luspatercept (ACE-536) in people who already took part in an earlier luspatercept study. It mainly helps doctors better understand ongoing side effects and overall safety over time.
Detroit, MichiganAges 18 years+ - NCT06701682RecruitingPhase 2
Study of vilobelimab for moderate to severe ARDS
This trial tests a drug called vilobelimab for people with moderate or severe ARDS (a serious lung condition). It aims to find if this treatment can help improve breathing and outcomes.
Detroit, MichiganAges 18 years+ - NCT05701917Recruiting
Clot-busting device versus blood thinners for leg clot
This study compares a clot-removal device (ClotTriever) plus standard care versus standard blood thinners alone for a deep vein clot in the leg. It aims to see which approach better improves leg symptoms and outcomes.
Detroit, MichiganAges 18 years+ - NCT06428019RecruitingPhase 3
Comparing drug combinations for untreated CLL or SLL
This trial tests two different drug combinations (venetoclax with obinutuzumab or with acalabrutinib) to see how they affect the risk of tumor lysis syndrome in people with untreated CLL or SLL. It may help find the safest and most effective way to start treatment.
Detroit, MichiganAges 18 years+ - NCT05066217RecruitingPhase 3
Study tests clemizole for Lennox-Gastaut seizures
This Phase 3 trial studies whether clemizole helps reduce seizures in people with Lennox-Gastaut syndrome (LGS) and checks safety. If you have LGS and meet the seizure and heart-safety requirements, this could be an option to explore.
Detroit, MichiganAges 2–55 - NCT04227847RecruitingPhase 1
Study of a CD70-targeting drug for blood cancer
This Phase 1 study tests the safety of SEA-CD70, a drug that targets CD70, in people with certain blood cancers like MDS and AML. It may help doctors learn whether this approach can be used safely for patients whose disease has come back or not responded to standard treatments.
Detroit, MichiganAges 18 years+ - NCT05702645Recruiting
Down syndrome long-term study after leukemia treatment
This study follows children and young adults with Down syndrome who have survived acute leukemia (ALL or AML) to learn about their longer-term health after treatment ends. It may help families and doctors understand what health problems to watch for and how to provide better follow-up care.
Detroit, MichiganAges 6–39 - NCT06703073RecruitingPhase 2
Testing new treatments for acute respiratory distress syndrome (ARDS)
This trial is testing new treatments for people with ARDS, a serious lung condition. The goal is to find therapies that help patients breathe better and recover faster. If you or a loved one has ARDS, this study may offer access to experimental treatments.
Detroit, MichiganAges 18 years+ - NCT04545424RecruitingPhase 2
Testing cooling treatment for severe lung failure in ICU patients
This trial tests whether therapeutic cooling (hypothermia) can improve outcomes in people with ARDS, a serious lung condition causing breathing failure. It may help by reducing harmful inflammation and lung injury, but eligibility is time-sensitive and requires ICU monitoring.
Detroit, MichiganAges 18–85
Hear when a new Down Syndrome trial opens near Detroit, MI
We’ll email you when one opens near Detroit, MI — at most once a week, no account needed, unsubscribe anytime.
Down Syndrome trials in other cities
Where these studies are running near Detroit
Institutions with a site for the recruiting down syndrome studies listed above.
- Henry Ford Health · 14 studies
- University of Michigan · 8 studies
- Wayne State University/Karmanos Cancer Institute · 4 studies
- Children's Hospital of Michigan · 3 studies
- John D. Dingell VA Medical Center · 2 studies
- Weisberg Cancer Treatment Center · 2 studies
- Barbara Ann Karmanos Cancer Institute
- Corewell Health Beaumont Troy Hospital
What taking part in a down syndrome study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting down syndrome studies in Michigan.
Common questions
- Are there down syndrome clinical trials near Detroit?
- Yes. We're currently tracking 80 recruiting down syndrome studies with a site near Detroit, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a down syndrome study near Detroit?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Detroit to take part?
- Not necessarily. These studies have a site near Detroit, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New down syndrome studies open near Detroit regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.