Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,057 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07614425Recruiting
Surgery for Carpal Tunnel Syndrome Study
This study tests surgical treatment for carpal tunnel syndrome—a condition where a nerve in your wrist gets compressed, causing numbness, tingling, or pain in your hand. You may qualify if you have confirmed carpal tunnel syndrome and conservative treatments like splints haven't helped.
HelsinkiAges 18–75 - NCT07616037RecruitingPhase 2
New hormone treatment for polycystic ovary syndrome
This study tests a new medication that combines two hormone-like drugs to treat polycystic ovary syndrome (PCOS), a condition affecting ovulation and hormone balance. The trial aims to see if this dual-action drug can improve irregular periods and other PCOS symptoms better than current treatments.
Shanghai, Shanghai MunicipalityAges 18–40 - NCT07618364Recruiting
Rinsing to reduce eye inflammation in dry eye disease
This study tests whether rinsing the eye surface helps reduce inflammation and symptoms in people with dry eyes. Participants must have a specific inflammatory marker (MMP-9) in both eyes.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07616089RecruitingPhase 1
Study of a new pill for advanced blood cancers
This trial tests a new pill for people with certain blood cancers that have not gotten better with standard treatments. It aims to see if the drug is safe and works, and it may help shrink tumors or slow the cancer.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT07619885RecruitingPhase 1
Testing a New Blood Thinner Called CG-0255 in Healthy People
This study tests how a new blood-thinning medication (CG-0255) works in the body and compares it with Plavix, a common blood thinner. Researchers will measure how much of the drug enters your bloodstream and what effects it has on your blood clotting ability.
Miami, FloridaAges 18–55 - NCT03888924RecruitingPhase 2
BCG vaccine for people with radiologically isolated syndrome
This trial tests whether a BCG vaccine can help people who have radiologically isolated syndrome (RIS), a condition where MRI scans show signs of possible multiple sclerosis before symptoms develop. The study aims to see if vaccination is safe and can change disease behavior over time.
RomeAges 18 years+ - NCT07609940RecruitingPhase 4
Linvoseltamab plus tocilizumab for heavily treated multiple myeloma
This trial tests a combination of two drugs (linvoseltamab and tocilizumab) for adults with multiple myeloma that has stopped responding to standard treatments. Tocilizumab is added to help reduce serious side effects from the main drug.
Los Angeles, CaliforniaAges 18 years+ - NCT07604467Recruiting
Understanding Stem Cells in Takotsubo Heart Syndrome
This study examines how certain stem cells (CD34+ cells) may contribute to takotsubo syndrome, a temporary heart condition often triggered by stress. By understanding this connection, researchers hope to improve treatment and recovery for patients with this condition.
Ljubljana, LjubljanaAges 18 years+ - NCT07606872Enrolling by invitation
Testing a diabetes score to guide treatment reversal
This study tests a new scoring system to help people with type 2 diabetes understand their condition better and potentially reverse or improve it. You'll use a digital platform to track blood sugar, answer health questions, and have blood tests to see if the system helps guide your treatment plan.
Manchester, EnglandAges 18 years+ - NCT07607418RecruitingPhase 2
Ivosidenib maintenance therapy for IDH1-mutated blood cancers
This trial tests whether taking ivosidenib as a maintenance drug (to keep the cancer in remission) works better than standard care for patients with IDH1-mutated AML or high-risk MDS who cannot undergo a bone marrow transplant. Ivosidenib is a targeted drug that blocks a specific mutation found in your cancer.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07610746Recruiting
Brain Blood Flow in Newborns Exposed to Opioids Before Birth
This study looks at how opioid exposure during pregnancy affects blood flow and brain function in newborns. Researchers will compare babies exposed to opioids in the womb with babies who were not exposed, to better understand how prenatal opioid exposure affects the developing brain.
Indianapolis, IndianaAges Up to 1 day - NCT06696287Recruiting
6-minute hand and arm test in fibromyalgia
This study tests a simple 6-minute hand and arm exercise (pegboard and ring test) in people with fibromyalgia. It helps researchers understand how well you can use your hands and arms during daily activities.
KırşehirAges 18–65 - NCT05279963Recruiting
Study for bladder pain using a nerve-based treatment (EA)
This trial tests whether a nerve-based therapy called EA can reduce bladder pain. It also aims to understand why the treatment may help by looking at underlying mechanisms.
Hangzhou, ZhejiangAges 18–70 - NCT05926271RecruitingPhase 2
Genotype-guided clopidogrel alone after stent placement
This trial looks at whether using clopidogrel by itself (without aspirin) works for people after a new drug-eluting stent, based on a blood test of how your body processes the drug. It may help reduce “extra blood-thinning” if you have a certain genetic type that responds well to clopidogrel.
Nieuwegein, UtrechtAges 18 years+ - NCT06714409Recruiting
Ultrasound-guided fluid removal in hospitalized heart failure
This study tests whether using ultrasound-guided treatment to reduce fluid buildup in the body can help people hospitalized for worsening heart failure feel better faster. It's for adults admitted with heart failure and high BNP levels.
OsloAges 18 years+ - NCT06694012Recruiting
Ohtori Study Part 2 heart health
This study looks at heart and metabolic health in the general population. It helps researchers understand how to prevent conditions like diabetes and heart disease.
Sakai, OsakaAges 20 years+ - NCT06715046Recruiting
Blood DNA test after stem cell transplant
This study checks if looking at DNA in your blood can help doctors see how well your stem cell transplant is working and catch any problems early. It is for people with blood cancers getting a transplant from a donor.
Milan, MilanAges 18 years+ - NCT03168802Recruiting
Ultrasound and nerve treatment for facet-joint low back pain
This study tests whether a procedure that uses focused ultrasound (MRgFUS) and/or a radiofrequency nerve treatment can reduce long-lasting low back pain caused by facet-joint arthritis. It may help people whose pain improves strongly after a targeted numbing injection to specific back nerves.
Taipei, Please SelectAges 20–79 - NCT07595926Recruiting
Proper Height Measurement in Ventilator Patients with Lung Injury
This study examines whether the way doctors measure height in sedated patients on breathing machines affects lung protection. Researchers will compare different measurement methods to see which one helps prevent breathing-machine-related lung injury in patients with severe lung failure (ARDS).
AmiensAges 18 years+ - NCT07597031Recruiting
Digital Lifestyle Platform for People Leaving Hospital Rehab
This study tests whether a smartphone or tablet app can help people stay healthy and active after leaving rehabilitation. The app guides you through daily activities and healthy habits to support your recovery at home.
Bern, Canton of BernAges 18 years+ - NCT07597343Recruiting
Helping You Stick With Hip Pain Exercise Treatment
This study tests new ways to help people with lateral hip pain (pain on the outer side of the hip) stay motivated and consistent with their exercise program. The goal is to understand what helps patients do their exercises regularly so they can feel better.
Leicester, LeictershaireAges 18 years+ - NCT05500989Recruiting
Compare early pregnancy blood-flow markers in preeclampsia
This study looks at blood-flow and artery health signs during pregnancy to better understand why preeclampsia happens. It compares women with preeclampsia to women with an uncomplicated pregnancy, and may help improve early detection and care.
MaastrichtAges 18 years+ - NCT05969275RecruitingPhase 2
Cell therapy trial for infection-related septic shock in ICU
This Phase 2 trial tests an immune-boosting cell therapy (umbilical mesenchymal stromal cells) in people with septic shock—when infection causes dangerous stress on the heart and other organs. The goal is to see if this treatment can improve outcomes compared with standard care.
Ottawa, OntarioAges 18 years+ - NCT07593404Recruiting
Testing a New Eye Drop for Dry Eye Disease
This study tests a new lubricating eye drop designed to relieve dry eye symptoms. If you have dry eye disease, this trial may help determine if the new formula works better than what's currently available.
Waterloo, OntarioAges 18 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,057 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.