Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,201 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07403929Recruiting
Fermented grape juice for fibromyalgia symptoms
This trial tests whether drinking fermented grape juice can help relieve fibromyalgia symptoms like pain and cramping. If you are a woman between 20 and 40 with mild excess weight and fibromyalgia, you may be eligible.
Istanbul, IstanbulAges 20–40 - NCT07345832Recruiting
Volunteer-led lifestyle program for older adults with muscle loss
This study tests a volunteer-led program to improve muscle health in older adults with sarcopenia. It uses a mobile app to guide exercise and nutrition, and aims to see if this approach helps people regain strength.
Hong KongAges 60 years+ - NCT06711666Recruiting
Maternal mental health and baby's brain in heart disease
This study looks at how a mother's mental health during pregnancy may affect the brain development of babies with a serious heart condition called critical cyanotic congenital heart disease (CHD). It aims to understand this link to improve support for families.
MarseilleAges Up to 50 years - NCT07413874Recruiting
Music therapy over video for depression and hormone disorder
This trial tests if telehealth music therapy can help adults who have both an endocrine autoimmune disease and depression. You'll join sessions from home using Zoom.
Boone, North CarolinaAges 18–65 - NCT06947460RecruitingPhase 1/Phase 2
CAR-T cell therapy for resistant lupus, sclerosis, and Sjögren's lung disease
This trial tests a special immune cell therapy (CAR-T cells targeting CD19 and BCMA) for people with lupus nephritis, systemic sclerosis, or Sjögren's-related lung blood vessel disease that hasn't improved with usual treatments. The goal is to see if this one-time cell infusion can calm the overactive immune system and improve symptoms.
Beijing, China,BeijingAges 10–65 - NCT07732894Recruiting
Exercise and Guided Imagery for Bowel Symptoms After Cancer Surgery
This study tests if combining gentle aerobic exercise with guided imagery (a relaxation technique using your imagination) can help improve bowel control and reduce symptoms after rectal cancer surgery.
IstanbulAges 18–65 - NCT07734584Recruiting
Reducing air bubbles during aortic repair with carbon dioxide
This trial tests a special flushing method using carbon dioxide gas to prevent air bubbles from entering the bloodstream during a procedure to fix the main artery in the chest. This could help avoid strokes or other complications.
Bologna, ItalyAges 18 years+ - NCT07498426RecruitingPhase 3
Study of NIO752 for progressive supranuclear palsy
This trial tests a new medicine called NIO752 for people with progressive supranuclear palsy (PSP), a condition that affects movement, balance, and thinking. The goal is to see if it can help slow the disease's progression.
Scottsdale, ArizonaAges 41–81 - NCT07555119Recruiting
Home Sleep Testing: Night-to-Night Measurement Variability Study
This study measures how sleep breathing patterns vary from night to night using home sleep testing. It helps researchers understand if portable sleep tests give consistent and reliable results.
BernAges 18 years+ - NCT04093570Enrolling by invitationPhase 2
Extension study for people continuing ASTX727 from a prior trial
This study checks whether continuing ASTX727 for people who already benefited from it in an earlier Taiho study is safe and effective. It may be an option if you stayed on ASTX727 at the end of your parent study and your doctor felt it was helping you.
Fountain Valley, CaliforniaAges 18 years+ - NCT06987058Enrolling by invitationPhase 2
Continued RVU120 treatment study for current participants
This trial is for people who are already in a RVU120 study and have been receiving the drug for at least 5 cycles. It allows you to keep getting RVU120 if you are benefiting from it and don't have other treatment options.
GdanskAges 18 years+ - NCT07525063Enrolling by invitation
Brain Stimulation for Fibromyalgia Pain Relief
This study tests whether a non-invasive brain stimulation technique (called TMS) can help reduce pain and improve mood in women with fibromyalgia. Researchers will use MRI scans and brain stimulation to understand how pain and reward circuits in the brain work.
Durham, North CarolinaAges 18 years+ - NCT07669558Recruiting
Finding the best side-lying position for ARDS after abdominal surgery
This trial uses a special imaging test (electrical impedance tomography) to find the safest side position for patients with lung injury after abdominal surgery in the ICU. It aims to improve oxygen levels and breathing comfort.
ShanghaiAges 18 years+ - NCT07728669Recruiting
Digital diet app for people on GLP-1 therapy
This study tests a smartphone app that gives dietary advice to people who are overweight or obese and also take a GLP-1 medication (like semaglutide) for weight or diabetes. The app will help you follow a healthy eating plan while using the medication.
AlmatyAges 21–65 - NCT07726940Recruiting
A Study of Immune Responses and ECMO in Severe Lung Injury
This study looks at how the immune system and ECMO (a machine that helps oxygenate blood) can improve outcomes for people with moderate to severe ARDS. If you join, researchers will monitor your condition and treatment to find better ways to manage this serious lung problem.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07726953Recruiting
Full-course ECMO for moderate-to-severe ARDS
This trial tests a full-course strategy using a heart-lung bypass machine (ECMO) for people with moderate-to-severe acute respiratory distress syndrome (ARDS), a serious lung condition. The goal is to see if starting and continuing ECMO throughout treatment improves recovery.
BeijingAges 18 years+ - NCT07429773Recruiting
Immune markers in stubborn pelvic pain
This study looks at the immune system's response in people with chronic pelvic pain that hasn't gotten better with first treatments. By measuring certain immune markers, the researchers hope to better understand why the pain persists and find new ways to help.
Nice, Alpes-MaritimesAges 18–40 - NCT05350748Recruiting
MDS study using detailed tests on blood and bone marrow
This study carefully evaluates people with myelodysplastic syndromes (MDS) and closely related blood disorders using detailed medical, blood, and bone marrow testing. The goal is to better understand these conditions and how they progress, which may help guide future care.
Bethesda, MarylandAges 1 day–120 years - NCT07723313RecruitingEarly Phase 1
Amniotic membrane and secretome for carpal tunnel release
This trial tests whether adding a special membrane (amniotic membrane) and a natural healing fluid (secretome) to standard carpal tunnel release surgery can improve hand function better than surgery alone. It may be a good option if your wrist pain and numbness haven't gone away with other treatments.
Denpasar, BaliAges 18 years+ - NCT05701917Recruiting
Clot-busting device versus blood thinners for leg clot
This study compares a clot-removal device (ClotTriever) plus standard care versus standard blood thinners alone for a deep vein clot in the leg. It aims to see which approach better improves leg symptoms and outcomes.
Scottsdale, ArizonaAges 18 years+ - NCT06576310Recruiting
Predicting teeth changes from sleep apnea mouthpiece treatment
This study looks at people with sleep apnea who are using a special mouthpiece (mandibular advancement device). It aims to find out which factors predict changes in how your teeth fit together after using the device.
ToulouseAges 18 years+ - NCT07348341Recruiting
Laser treatment for blocked heart arteries registry
This study collects information from patients with blocked heart arteries who receive a special laser treatment (ELCA) to open the blockage. It will help doctors understand how well this laser works in different situations.
MadridAges 18 years+ - NCT07720323Recruiting
Can a wristband help with long-term nausea and vomiting?
This study tests if a special wristband (EmeTerm) can reduce nausea and vomiting symptoms in people who have had these problems for more than two months. You will use the band and report your symptoms through online surveys.
Columbus, OhioAges 18 years+ - NCT06194305RecruitingPhase 2
Brain and behavior study of tic therapy for kids
This study tests a behavioral therapy (CBIT) for children with tics. It uses brain scans (MRI and EEG) to see how the therapy works. It may be a good fit for a child who has had tics for at least a year and hasn't had much of this therapy before.
San Diego, CaliforniaAges 10–17
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,201 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.