Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,055 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05960929RecruitingPhase 3
Breathing support for premature babies with lung distress
This Phase 3 trial tests whether InfasurfAero™ (a type of surfactant given as aerosol) works better than a sham treatment in preterm babies with respiratory distress syndrome (RDS). It aims to improve breathing in the first hours of life for babies who need CPAP.
Phoenix, ArizonaAges 7 months–8 months - NCT07258290Recruiting
Freesolve Magnesium Scaffold for Heart Artery Blockages
This trial tests a new dissolvable magnesium scaffold to treat blockages in heart arteries. It is designed for people with stable heart pain or certain recent heart attacks, and it aims to open blocked arteries and then slowly dissolve over time.
Washington D.C., District of ColumbiaAges 18–80 - NCT07252245Recruiting
Improving how emergency teams decide who needs urgent heart care
This study is testing a way to help doctors decide which patients with chest pain need immediate transfer to a cardiac emergency department. It aims to improve the process of triaging patients who might be having a heart attack.
HapsAges 18 years+ - NCT07255313Recruiting
Boosting Resilience in Healthcare Workers with Mind-Body and Nutrition
This trial tests a program that includes mind-body practices and nutrition to help healthcare workers cope with stress and build resilience. If you work at University Medicine Essen and feel your resilience could improve, you may be eligible.
EssenAges 18 years+ - NCT07256795Enrolling by invitation
ME/CFS after COVID-19 vs. before the pandemic
This study looks at how the brain's protective barrier and immune system work in people with ME/CFS, comparing those who got sick before the COVID-19 pandemic to those who developed ME/CFS after a COVID-19 infection. It aims to understand why some people have lasting brain fog, fatigue, and other neuropsychiatric symptoms.
Baltimore, MarylandAges 18–70 - NCT07251179Recruiting
Understanding immune cells in autoimmune diseases and immune deficiencies
This study looks at immune cells in people with certain autoimmune diseases or immune deficiencies. The goal is to understand how these cells work, which may help improve future treatments.
StrasbourgAges 18–70 - NCT06903026Recruiting
Memory loss and sleep apnea: a study
This study looks at whether people who have had a specific kind of temporary memory loss (transient global amnesia) also have sleep apnea. If you fit, your past medical data may be used to help find a link.
StrasbourgAges 18 years+ - NCT06109337Recruiting
Immune cells in children with ADHD
This study looks at immune system cells in the blood of children with ADHD. It aims to understand how these cells might be different, which could lead to new treatment ideas.
Hangzhou, ZhejiangAges 6–12 - NCT07242573Recruiting
Exercise and brain stimulation for fibromyalgia
This study tests if combining physical exercise with a gentle brain stimulation technique can improve pain, sleep, and fatigue in people with fibromyalgia.
Warsaw, Masovian VoivodeshipAges 20–80 - NCT04903262Recruiting
Extra CO2 removal to protect lungs in moderate ARDS
This study tests an “extra-CO2 removal” breathing support approach to help protect the lungs in people with moderate ARDS, a serious lung injury. You would be on a ventilator for a short time, and the team would check whether this approach improves breathing outcomes while aiming to be safer for the lungs.
BolognaAges 18–100 - NCT07246096RecruitingEarly Phase 1
CAR-T cell therapy for autoimmune diseases
This trial tests a new CAR-T cell treatment for people with certain autoimmune diseases that have not responded to standard therapies. The treatment uses your own immune cells modified to target and attack disease-causing cells.
ShanghaiAges 18–70 - NCT07246265Recruiting
Morphine clearance study for sickle cell crisis in ICU
This study looks at how the body clears morphine in adults with sickle cell disease who are in the intensive care unit (ICU) for a pain crisis or acute chest syndrome and are receiving morphine through a patient-controlled analgesia (PCA) pump. The goal is to understand how kidney function affects morphine breakdown.
Tours, FranceAges 18 years+ - NCT07242131Recruiting
Birth control, progesterone, or inositol for regulating periods in PCOS
This trial tests three treatments—birth control pills, progesterone, and inositol—to see which best helps regulate menstrual cycles in women with PCOS. It aims to find an effective option that is safe and easy to use.
Izmir, MenemenAges 18–40 - NCT07248449Recruiting
Exercise study for children with Down syndrome ages 3-8
This trial tests two types of exercise—Cuevas Medak and rebound exercises—to see which one improves physical fitness in children with Down syndrome. It may help your child get stronger and move better.
Lahore, Punjab ProvinceAges 3–8 - NCT07249060Recruiting
Interferon levels in cancer and autoimmune disease patients
This study looks at a protein called interferon in the blood of people with cancer who are starting immunotherapy, and people with certain autoimmune diseases (such as lupus, Sjögren's syndrome, scleroderma, or inflammatory myopathy). The goal is to compare interferon patterns and better understand immune responses.
Pamplona, NavarreAges 18 years+ - NCT07248995Recruiting
Ultrasound to set breathing support in brain injury patients with lung issues
This trial tests if chest and head ultrasound can help doctors adjust the breathing machine (PEEP) for patients with both a severe brain injury and a serious lung condition called ARDS. The goal is to improve care without harming the brain.
ThessalonikiAges 18 years+ - NCT07246993Recruiting
Brain training for ongoing symptoms after concussion
This trial tests if a gentle brain stimulation technique called tDCS can help people with persistent memory or thinking problems after a mild concussion. You will use a smartphone app and may receive active or placebo stimulation over several sessions.
Minneapolis, MinnesotaAges 18–65 - NCT07248514Recruiting
Pilates for kids with backpack-related back pain
This study tests if Pilates exercises can help children aged 12-16 who have back pain and poor posture from carrying heavy backpacks.
Lahore, Punjab ProvinceAges 12–16 - NCT06906432Recruiting
Brain-Heart Injury After Brain Bleed Study
This study looks at how a brain bleed can affect the heart. Researchers hope to understand the link between brain and heart injury to help improve care for people who have had a brain bleed.
Beijing, Beijing MunicipalityAges 18–80 - NCT07237464RecruitingPhase 1
Safety study of GB18 injection in healthy adults
This early-phase trial tests a new injection called GB18 in healthy adults to see if it is safe and how the body processes it. It may help researchers understand how to treat conditions that involve the immune system.
Beijing, Beijing MunicipalityAges 18–55 - NCT07231120RecruitingPhase 1
Testing SXRN injection for cancer-related weight loss
This trial tests a new injection called SXRN for people with advanced cancer who have lost weight and appetite (cancer cachexia). The goal is to see if it is safe and might help improve weight and appetite.
Beijing, Beijing MunicipalityAges 18–75 - NCT06247046RecruitingPhase 3
Probiotic powder for IBS-D (SK08) trial
This study tests a new probiotic powder (SK08) to see if it reduces belly pain and diarrhea in people with IBS-D (irritable bowel syndrome with diarrhea). It lasts several months and involves taking the study powder twice a day.
Wuxi, JiangsuAges 18–70 - NCT07231835Recruiting
Coronary outcomes with drug-coated balloon treatment
This study tracks patients who receive a special balloon coated with medicine (paclitaxel) to open blocked heart arteries. It aims to understand how well this treatment works for various types of blockages.
AmsterdamAges 18 years+ - NCT07238686RecruitingPhase 2
Venetoclax plus microtransplant for higher-risk MDS
This study tests a combination of venetoclax (a targeted drug) with a mini stem cell transplant (called a microtransplant) using a partially matched donor. It is for people with higher-risk MDS who cannot have a standard transplant.
BeijingAges 18 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,055 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.