Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,196 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05675878RecruitingPhase 3
Testing a specific diet for Gulf War illness
This Phase 3 study tests whether following a study diet can improve symptoms of Gulf War illness. It may help people by confirming whether diet changes are an effective treatment.
Washington D.C., District of ColumbiaAges 50–75 - NCT05687149Recruiting
Study of mouth and throat cancer patterns in Fanconi anemia
This study looks at how squamous cell carcinoma (a type of cancer) naturally develops over time in people with Fanconi anemia. It may help doctors better recognize warning signs and plan care in the future.
Bethesda, MarylandAges 8–90 - NCT05689944Recruiting
Dance therapy for teens with chronic pain
This trial studies whether dance therapy can help reduce chronic pain in teens when usual pain treatments haven’t worked well. It may be helpful if you’re followed in a pain clinic and are able to participate in movement-based sessions.
BronAges 12–20 - NCT05698446Recruiting
Compare ankle surgery options for lateral ankle instability
This study compares different surgical techniques to treat ongoing (chronic) pain and instability on the outside of the ankle. If you qualify, your care team will determine which surgery approach best fits your situation and then track your outcomes.
BeijingAges 18–60 - NCT05705999Recruiting
TMS treatment plus CBIT study for Tourette’s tics
This trial tests whether a treatment called TMS, added to an evidence-based therapy called CBIT, can reduce Tourette’s tics more than CBIT alone. You may be assigned to different study groups, and they will also use brain imaging to measure changes.
Morgantown, West VirginiaAges 18–100 - NCT05706922Recruiting
Study gut and vaginal bacteria in PCOS women
This study looks at differences in gut and vaginal bacteria in people with PCOS (a hormone-related condition). You may help researchers understand what bacterial patterns are linked to PCOS and why that might matter for symptoms.
Rotterdam, South HollandAges 18–45 - NCT05713435Recruiting
CO2 or Erbium laser treatment for vaginal dryness in breast cancer survivors
This study compares two types of laser treatments to improve vaginal discomfort (GSM) in people who had breast cancer and are now dealing with menopause-related symptoms. If you qualify, you may be assigned to one of the laser types to see which works better and is easier to tolerate.
Leuven, Flemish BrabantAges 18–100 - NCT05719545Recruiting
Study of people getting a heart procedure through the skin
This study follows people who have an acute heart problem and need a heart procedure done through the skin. It may help researchers better understand care for people in this urgent situation.
Jinan, ShandongAges 18–85 - NCT05719935Recruiting
KinematX wrist replacement registry for people with wrist arthritis
This trial is a registry that follows people who get (or already had) a KinematX total wrist replacement. It collects health and recovery information to better understand outcomes for different wrist problems, like arthritis or certain bone alignment issues.
Loma Linda, CaliforniaAges 18–85 - NCT05724173Recruiting
Test of a brain-to-computer device for ALS hand paralysis
This study checks whether a brain-computer interface (a BrainGate2 system) is safe and workable for people with ALS. If you qualify, you may be asked to try the device and complete study tasks to help researchers learn how well it can support communication or control.
Stanford, CaliforniaAges 18–80 - NCT05726786RecruitingPhase 3
Immunonutrition before bladder removal surgery
This study tests whether a special nutrition drink given before open bladder surgery can reduce complications and improve the body’s immune response after surgery. It’s for adults having bladder removal and is compared against standard care.
Lausanne, Canton of VaudAges 18 years+ - NCT05731024Recruiting
Closed-loop breathing control vs standard care for kids in ICU
This study compares a computerized “closed-loop” system that helps match breathing support to a child’s needs versus usual (standard) breathing control. It’s for critically ill children on a breathing machine, aiming to improve synchronization between the child and the ventilator.
AydinAges 1 month–18 years - NCT05735444Recruiting
CPAP registry for sleep apnea in people with high blood pressure
This study keeps a record of people with obstructive sleep apnea (OSA) who also have high blood pressure, to better understand how CPAP is used and what outcomes happen. It may help your care team by contributing your information to a large multi-center study in China.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05736146Recruiting
Testing Gulf War illness blood markers for better diagnosis
This study checks blood tests to see whether they can help confirm Gulf War illness. If you qualify as having Gulf War illness (or are a similar Gulf War veteran without it), your blood and health information may be used to validate these marker tests.
Palo Alto, CaliforniaAges 35 years+ - NCT05737342Recruiting
Test supplement to lower A1c and steady blood sugar
This trial studies ANKASCIN 568-P products to see if they can lower A1c (a blood sugar average) and help regulate blood glucose. It may help people with early blood sugar problems, but you must avoid diabetes medicines during the study.
TaipeiAges 20 years+ - NCT05737121RecruitingPhase 2
Study drug for bladder pain compared with lidocaine, heparin, or placebo
This Phase 2 trial tests VNX001 to see if it helps people with interstitial cystitis/bladder pain syndrome (IC/BPS) compared with its separate ingredients (lidocaine and heparin) or a placebo (inactive treatment). You may be eligible if you have had IC/BPS for months and recently had a moderate-to-severe bladder pain flare.
Escondido, CaliforniaAges 18 years+ - NCT05740579Recruiting
Storing eggs in teens with Turner syndrome variants
This study looks at freezing and storing eggs (cryopreservation) in children and teens with Turner syndrome or related genetic variants. It may help preserve the chance of having biological children later, if you are able to undergo the study procedures safely.
AarhusAges 2–17 - NCT05745805Recruiting
Study of brain scans after the first COVID wave
This study checks how COVID affected people’s health and brain changes using follow-up information and brain scans. It may help researchers understand longer-term effects and what to watch for after COVID, especially in people with mild or moderate illness.
Xi'an, ShaanxiAges 18–65 - NCT05745285Recruiting
LLS care support program for blood cancer patients
This study looks at whether LLS services and support improve outcomes and the day-to-day experience of care for people with leukemia, lymphoma, myeloma, MDS, or MPN. It’s mainly about matching you to the right support and following your progress for 6 months.
Miami, FloridaAges 18 years+ - NCT05751525Recruiting
Oral sulfonylurea study for children with KCNJ11-related delay and epilepsy
This study looks at whether switching to an oral sulfonylurea medicine can improve thinking, development, and seizure-related outcomes in children with a specific KCNJ11 gene change. You may be able to join if your child already has this mutation and has been able to take the medicine by mouth.
Chicago, IllinoisAges 2–50 - NCT05767203Recruiting
Study genetic and blood markers in people with inherited intellectual disability
This study looks at genetic-related and blood/biologic markers in people with an inherited (genetic) intellectual disability. The goal is to better understand these differences and how they might relate to the condition.
ParisAges Any age - NCT05767619Recruiting
Digital tool to guide care for chest pain calls
This trial tests a digital decision-support tool that helps emergency teams manage people who call for help because of chest pain. It may improve how safely and consistently chest pain is assessed and treated in the ambulance setting.
Kungsbacka, Region HallandAges 18 years+ - NCT05767671Recruiting
Breathing tube patients in ICU tested for lung inflammation treatment
This trial studies whether changing immune cells in the lungs (using a procedure called MiniBAL) can improve outcomes in adults who are critically ill and on a breathing tube. It may help doctors better manage acute lung injury by targeting inflammation early in the ICU stay.
Denver, ColoradoAges 18–99 - NCT05776511Recruiting
Eye Movement Test for White Matter Brain Changes
This study tests whether a special eye-tracking camera can help diagnose the cause of white matter hypersignals—unusual bright spots seen on brain MRI. Researchers want to see if eye movements can reveal clues about what's causing these brain changes.
NiceAges 18 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,196 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.