Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,387 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06006806Recruiting
Proton therapy skin effects study for breast cancer
This study looks at how proton therapy affects the skin in people being treated for early-stage breast cancer. It aims to understand skin reactions better so doctors can reduce side effects.
Knoxville, TennesseeAges 18 years+ - NCT06621394Recruiting
Mediterranean diet and mindful eating for depression and obesity
This study tests if a Mediterranean diet combined with mindful eating can help reduce depression severity in people who have both obesity and major depressive disorder. You would follow a special eating plan and learn mindfulness techniques to see if they improve your mood.
StuttgartAges 18 years+ - NCT06261736Recruiting
Antibiotics before urethral bulking to prevent infection
This trial tests whether taking antibiotics before a urethral bulking procedure can help prevent infections. It is for people who are scheduled for this procedure and have no history of recurrent UTIs or bladder problems.
Morristown, New JerseyAges 18 years+ - NCT06183268Recruiting
Proton therapy for head and neck cancer skin side effects
This study looks at how proton therapy affects skin in people with head and neck cancer. It aims to better understand and manage skin reactions during treatment.
Knoxville, TennesseeAges 18 years+ - NCT07220876Recruiting
VisiPlate implant for hard-to-control open-angle glaucoma
This trial tests a new device called VisiPlate that is placed in the eye to help lower pressure for people with hard-to-control open-angle glaucoma. It may be an option if standard treatments haven't worked well enough.
Glendale, ArizonaAges 45 years+ - NCT07218185Enrolling by invitation
Fibrinogen treatment for severe bleeding after trauma
This study tests an investigational treatment called INTERCEPT Fibrinogen Complex (IFC) for people with severe bleeding after a traumatic injury. The treatment helps restore a key blood-clotting protein to try to stop the bleeding and improve survival.
Aurora, ColoradoAges 18 years+ - NCT07219407RecruitingPhase 2
Long-term safety study of RAP-219 for focal seizures
This study tests the long-term safety and effectiveness of RAP-219, an investigative medication for focal epilepsy. It is for people who already completed an earlier study of RAP-219, have a type of epilepsy that doesn't respond to standard medicines, and use a surgically implanted brain device (RNS system) to help manage seizures.
Boise, IdahoAges 18–70 - NCT07218627RecruitingPhase 1
Study of an investigational medicine for heart failure
This study tests an experimental medicine called NNC0537-1482 for people with heart failure. It aims to see if the medicine helps improve symptoms and heart function.
LondonAges 40–75 - NCT07220252RecruitingPhase 2/Phase 3
Ublituximab for children with relapsing multiple sclerosis
This trial tests a new drug called ublituximab to see if it can reduce flare-ups in children and teens who have relapsing multiple sclerosis. It aims to understand if the treatment is safe and effective for younger patients.
GdanskAges 10–17 - NCT07216872Recruiting
Deep TMS to reduce heavy drinking in alcohol use disorder
This trial tests a non-invasive brain stimulation device (Deep TMS) to help people with alcohol use disorder reduce or stop heavy drinking. It uses magnetic pulses to target brain areas linked to addiction.
Tuscaloosa, AlabamaAges 18–86 - NCT06861582Recruiting
Faster troponin test for chest pain in the ER
This study tests a faster way to measure a heart-muscle protein (troponin) in the emergency room, to see if it can help doctors decide sooner whether your chest pain is from a heart attack. If you are having chest pain that started a few hours ago, you may be able to join.
São PauloAges 18 years+ - NCT07215533Recruiting
Exercise trials for teens and young adults at risk for diabetes
This study compares two types of exercise—high-intensity interval training (HIIT) and time-restricted eating (TRE)—to help lower the risk of developing type 2 diabetes in teens and young adults who are overweight or have obesity.
Syracuse, New YorkAges 14–30 - NCT07212504Recruiting
Brain stimulation to improve memory in older adults with mild memory problems
This study tests a new type of brain stimulation called accelerated neuromodulation, aimed at improving memory and thinking in older adults with mild memory issues. It uses magnetic pulses to gently stimulate a part of the brain linked to memory.
Toronto, OntarioAges 55–85 - NCT07212803RecruitingPhase 4
Energy drinks study for young healthy adults
This study looks at how energy drinks affect your heart. It compares the effects of two different energy drinks on heart rate and other heart measures. You will have several short visits where you drink an energy drink and get your heart checked.
Stockton, CaliforniaAges 18–40 - NCT07216937Recruiting
Comparing 3D-printed vs. regular ear tip comfort
This study compares how comfortable 3D-printed ear tips are versus regular ear tips for people with normal hearing.
Tucson, ArizonaAges 18–89 - NCT07219498Recruiting
Probiotics for muscle soreness after exercise
This trial tests whether taking a probiotic supplement for 5 weeks can reduce muscle soreness after exercise. If you exercise regularly and are generally healthy, you may be able to join.
Minneapolis, MinnesotaAges 18–30 - NCT07216716Recruiting
Health app recommendation tool for Alzheimer's caregivers
This study tests a tool that helps find health apps for people caring for a loved one with Alzheimer's or a related dementia. It aims to see if the tool makes it easier to choose useful apps for your caregiving journey.
Pittsburgh, PennsylvaniaAges 18–65 - NCT07216755Recruiting
Breathing training and nitrate for altitude exercise
This study tests whether breathing training and a natural nitrate supplement (from beets) can improve how well you exercise in conditions that simulate high altitude. You'll do cycling workouts while we measure your performance.
Daytona Beach, FloridaAges 18–40 - NCT07213063Recruiting
Creatine and HMB supplements for Down syndrome
This trial tests whether taking creatine and HMB supplements can improve muscle strength, reduce inflammation, and increase muscle mass in people with Down syndrome. It may help if you or your loved one can do basic physical tests like standing from a chair and do not have kidney disease or severe mobility issues.
Burgos, BurgosAges 18 years+ - NCT07215169Recruiting
Manual lymph drainage for head and neck lymphedema
This study tests whether manual lymph drainage, a gentle massage technique, can reduce swelling in the head and neck after radiation therapy for throat cancer. It may help people who have completed treatment within the last year.
Lund, Skåne CountyAges 18 years+ - NCT07213245Recruiting
Short-term effects of ultra-processed foods on metabolism
This study tests how eating ultra-processed foods for a short time affects your metabolism. If you are a healthy adult with a normal BMI, no diabetes, and no major dietary restrictions, you may be able to participate.
GothenburgAges 18–50 - NCT07218549RecruitingPhase 1
Study of psychoactive substances in people with past opioid use
This trial tests how safe certain psychoactive substances are and what effects they have in people who have used opioids in the past but are not currently dependent on them. It aims to gather information that could help future treatment options.
Houston, TexasAges 18–55 - NCT07216820Recruiting
Nerve blocks for shoulder surgery in obesity
This study compares two types of nerve blocks for shoulder surgery in people with obesity. It tests whether a block that spares the phrenic nerve (which helps you breathe) can keep your breathing strength stronger after surgery.
Chapel Hill, North CarolinaAges 18 years+ - NCT07216339Recruiting
Can a game make the walking test more fun for kids?
This study tests if adding game-like features to a standard 6-minute walking test makes it more engaging for children with muscle or nerve disorders. It may help kids stay motivated and perform better during the test.
Lexington, KentuckyAges 6–12
Hear when a new Effectiveness trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,387 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.