Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,374 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05205317Recruiting
VR alone or VR plus metformin for C-section scar healing
This study compares two treatments to help improve a C-section scar defect (an issue seen on the uterus scar). Some participants may receive virtual reality (VR) therapy plus metformin, while others receive VR alone, and the researchers will look at symptoms and scar healing.
Shanghai, Shanghai MunicipalityAges 18–40 - NCT01629017Recruiting
Long-term follow-up after a stem cell transplant
This study looks at the long-term health effects of hematopoietic (blood-forming) stem cell transplants. It may help doctors better understand and manage late side effects for children and teens after transplant.
Stanford, CaliforniaAges Up to 18 years - NCT05172973Recruiting
New valve procedure for failing aortic bioprosthetic valves
This trial studies whether a new transcatheter aortic valve (SAPIEN X4) is safe and works well in people whose previously implanted aortic valve is now failing. It may help reduce valve symptoms in higher-surgery-risk patients who are not good candidates for open-heart valve replacement.
Newport Beach, CaliforniaAges Any age - NCT05172960Recruiting
Study of a new heart valve for severe aortic stenosis
This trial tests a new version of a heart valve (SAPIEN X4) placed without open-heart surgery. It's for people with severe aortic stenosis who have symptoms like shortness of breath or chest pain.
La Jolla, CaliforniaAges Any age - NCT05156983RecruitingPhase 3
Reversal drug for urgent surgery in people on Factor Xa blood thinners
This Phase 3 study tests TAK-330, a reversal (blocking) medicine, to reduce bleeding risk during urgent surgery for adults taking Factor Xa inhibitors like rivaroxaban, apixaban, or edoxaban. It’s for situations where surgery can’t wait and doctors need a fast way to restore normal clotting.
Arkansas City, ArkansasAges 18 years+ - NCT05139719RecruitingPhase 2
HEC585 trial for slowing lung scarring decline
This Phase 2 study tests whether HEC585 can slow the decline in lung function in people with progressive fibrosing interstitial lung disease (PF-ILD). It may help preserve breathing capacity and breathing tolerance over time.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05137054RecruitingPhase 1
Linvoseltamab combo for hard-to-treat multiple myeloma
This trial tests a new drug called linvoseltamab combined with other cancer treatments for people with multiple myeloma that has stopped responding to standard therapies. It may be an option if you have already tried several treatments and are looking for a new approach.
La Jolla, CaliforniaAges 18 years+ - NCT05168462RecruitingPhase 4
Lower blood pressure goal in heart-attack shock patients
This study compares two blood pressure targets in people with cardiogenic shock after a heart attack. It looks at whether the lower target can improve outcomes and help evaluate treatment costs.
AmsterdamAges 18 years+ - NCT05160987Recruiting
Sedation choice for ICU patients on breathing machines
This study compares two sedation medicines—remimazolam vs midazolam—for very sick ICU patients who are on a breathing machine. It looks at whether one sedative works better or is safer for keeping patients comfortable while they’re critically ill.
Guangzhou, GuangdongAges 18–80 - NCT05142735Recruiting
NAC for early psychosis risk symptoms
This trial studies whether NAC (a nutrient-like supplement) can reduce symptoms in people who are at high risk for developing psychosis. It may help by testing a safer, non-standard treatment approach for early warning signs.
Toronto, OntarioAges 16–35 - NCT05179759Enrolling by invitation
School and teacher program for early grades in rural India
This study tests a school/teacher approach (rolled out in real school settings) to improve teaching for early primary students. It will include rural primary schools and the teachers and students in classrooms for grades 1–4.
Darjeeling, West BengalAges 5 years+ - NCT05142943Recruiting
Virtual reality to improve arm function after spinal cord injury
This study tests whether a virtual reality program that creates a feeling of body ownership can help improve arm and hand movement in people who have an incomplete spinal cord injury in the neck. It aims to find a new, engaging way to boost recovery.
Valencia, ValenciaAges 18–99 - NCT05137119RecruitingPhase 4
Adaptive study of treatments for staph bloodstream infection
This trial tests the best treatment approach for bloodstream infections caused by Staphylococcus aureus (“S. aureus”). It uses a flexible design to decide which treatment track you fit into, and may help improve recovery while avoiding unnecessary medications.
Houston, TexasAges Any age - NCT05142683Recruiting
Test an integrated care plan for teens with depression
This study tests whether a structured, coordinated care pathway helps teens (and their caregivers) manage depression better than usual care. It aims to see if targeted treatment and follow-up improve depression symptoms over time.
Toronto, OntarioAges 13–18 - NCT05195515Enrolling by invitation
Study on bladder cancer late effects and quality of life
This study looks at how long-term (late) effects after bladder cancer treatment affect quality of life. You may join if you recently had blood in your urine and are being evaluated for it in a specific region of Denmark.
Aarhus NAges 18 years+ - NCT05147831Recruiting
Remote arm treatment to prevent kidney injury from contrast dye
This trial tests whether a simple “arm conditioning” technique done remotely before a procedure can help prevent kidney injury caused by contrast dye used during certain heart catheter tests. You might benefit if you’re having a coronary angiogram and your kidney function is reduced, but you’re not on dialysis.
Galveston, TexasAges 18 years+ - NCT04930029Recruiting
Long-term follow-up after gastric bypass with an omega limb
This study looks at long-term side effects years after gastric bypass surgery done in a specific way. If you had this type of surgery and agree to an endoscopy with small tissue samples at 10 years, you may help doctors understand longer-term outcomes.
LilleAges 18 years+ - NCT05044273Recruiting
Study of two new stents and their safety in adults
This study checks how safe and effective two types of heart stents (Synergy XD and Synergy Megatron) are after they are placed. You might consider it if you’re an adult getting one of these stents and can follow required clinic visits.
AnyangAges 19 years+ - NCT05121051RecruitingPhase 2
Broccoli sprout extract to reduce tobacco cancer-causing chemicals
This Phase 2 study tests whether broccoli sprout extract (Avmacol ES) can reduce cancer-causing substances linked to heavy smoking. It’s for adults who smoke heavily and may help lower harmful tobacco-related chemical effects in the body.
Tucson, ArizonaAges 18 years+ - NCT05136703Recruiting
Study depression treatment effects in people living with HIV
This study looks at how depression and its treatment may affect the brain and immune-related body systems in people with HIV. You may be eligible if you have depression and a well-controlled HIV viral load, and you can safely complete brain MRI scans.
Coral Gables, FloridaAges 18 years+ - NCT05095909Recruiting
Frozen compression at intervals vs regular icing after shoulder surgery
This trial tests whether using a special device that gives cold in pulses (intermittent cryo-compression) helps the shoulder feel better after arthroscopic rotator cuff repair compared with traditional icing. It may help with pain and recovery during the early healing period after surgery.
Plymouth, MinnesotaAges 18–70 - NCT05095740Recruiting
Testing brain stimulation for laryngeal dystonia symptoms
This study tests whether a noninvasive brain stimulation treatment (referred to as neuromodulation, such as rTMS) can improve symptoms of laryngeal dystonia. It’s meant to see if stimulating certain brain areas can reduce how severely your voice/throat problem affects you.
Boston, MassachusettsAges 21–85 - NCT05104502Recruiting
Study how 36-hour water fasting affects immune signals
This study looks at how a 36-hour water-only fast changes immune-related markers and gut (microbiome) signals in healthy adults. It may help researchers understand how fasting could affect health, even though this trial is focused on people without major medical conditions.
Sacramento, CaliforniaAges 20–40 - NCT05107947Recruiting
Dynamic room lighting to improve sleep and daily body rhythm
This study tests whether changing the light in a hospital room can improve sleep and help your body clock work better in older adults. It may be most helpful if sleep problems or irregular daily rhythms are affecting you in the hospital.
MalmöAges 65 years+
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,374 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.