Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,374 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04218409RecruitingEarly Phase 1
Tests a spray to reduce opioid use and pain
This early trial studies whether Syntocinon can lower pain and help reduce how much opioids people use. It checks safety and the best dose by giving participants the study drug under close medical monitoring.
Gainesville, FloridaAges 21–45 - NCT04397159Recruiting
Exercise program to reduce tiredness in some kidney patients
This trial studies whether doing a combination exercise program can reduce “fatigability,” meaning feeling unusually tired or weak during activity, in Veterans with moderate-to-advanced chronic kidney disease. It also compares results with people without kidney disease and checks for safety, especially for heart and joint health.
Washington D.C., District of ColumbiaAges 50–85 - NCT04443530Recruiting
Testing Ultimaster stents in everyday patient care
This trial looks at how safe and effective two specific stents are when doctors use them as part of routine care. You may be a candidate if you’re an adult receiving one of these Ultimaster stents and can follow the study check-in schedule.
ChuncheonAges 19 years+ - NCT04395937Recruiting
Study of gentle aerobic exercise to improve severe asthma control
This trial studies whether a lower-intensity aerobic exercise program (not maximal effort) can improve asthma symptoms and control. It is meant for adults with asthma who are still not well controlled despite current inhaler treatments.
Liège, LiegeAges 18–65 - NCT04458584Recruiting
Thumb surgery trial comparing treatments for basal joint arthritis
This study looks at how well different thumb (basal joint) surgery approaches restore strength and function. You would be having planned (non-replacement) thumb surgery, and your chosen surgeon would care for you while researchers compare outcomes.
Lebanon, New HampshireAges 21 years+ - NCT04425395Recruiting
Sounds without words may change pain tolerance
This study looks at whether nonverbal vocal sounds (like certain tones or sounds) change how much pain you can tolerate. You might be asked to listen to or produce sounds while your pain response is measured.
Saint-EtienneAges 18–60 - NCT04441151Recruiting
Pulmonary rehab for adults on high-flow oxygen therapy
This trial tests whether pulmonary rehabilitation (supervised breathing and activity training) improves outcomes for adults who need high-flow oxygen. You may be eligible if your breathing and heart/vital signs are stable and your oxygen level is above a certain threshold.
Beijing, Beijing MunicipalityAges 18–100 - NCT04446273Recruiting
Robotic therapy timing to improve arm movement after stroke
This trial studies whether giving robotic therapy to the shoulder and arm in a “priority” way (instead of focusing on the hand first) helps improve arm movement in people with chronic stroke. It may help by improving how your arm muscles and joints are trained to work together.
Taipei, TaipeiAges 20–75 - NCT04401982RecruitingPhase 4
Testing eye drops for blood flow in high eye pressure and glaucoma
This study tests whether three different eye drop treatments (netarsudil, latanoprost, or both together) can improve blood flow to the white part of the eye and the retina. It may help people with high eye pressure or who are glaucoma suspects better understand how these treatments work.
Baltimore, MarylandAges 18 years+ - NCT04436965RecruitingPhase 3
Standard nutrition support for malnourished nasopharyngeal cancer patients
This Phase 3 study tests whether giving a standard nutrition plan can improve nutritional status and outcomes in people with locally advanced nasopharyngeal cancer who are malnourished. It mainly checks whether nutrition support helps you tolerate treatment and do better over time.
Guangzhou, GuangdongAges 18–65 - NCT04471129Recruiting
Noninvasive breathing support after heart surgery to protect heart function
This study tests whether two noninvasive breathing/oxygen treatments after cardiac surgery help improve heart function. It may benefit people with weak pumping function who are recovering in the hospital and can safely use these devices.
RouenAges 18 years+ - NCT04395196RecruitingPhase 2
Prenatal choline for pregnancy after alcohol exposure
This trial tests whether taking a choline supplement during pregnancy can reduce harmful effects on the baby when a person drinks heavily while pregnant. It may help support healthier pregnancy and baby outcomes for those who meet the study’s drinking and nutrition criteria.
Cape Town, Western CapeAges 18–45 - NCT04421768Recruiting
Training for cervical exams in labor and delivery care
This trial studies whether a structured training program helps healthcare staff perform cervical exams more effectively during labor. It may improve how labor and delivery care is delivered at the hospital.
Winston-Salem, North CarolinaAges Any age - NCT04477460Recruiting
Testing thicker feeds for babies after unexplained brief events
This trial looks at whether using thicker baby feeds can improve health outcomes for infants who have had their first “brief resolved unexplained event” (a short episode with no clear cause). It may help babies who are being monitored after this first episode.
Boston, MassachusettsAges birth–1 year - NCT04444362Enrolling by invitation
Probacine to protect organs after cardiovascular surgery
This study tests whether a medicine called Probacine can help protect your gut and organs after cardiovascular surgery. If you qualify, you may be asked to take part and follow the study plan to see if complications are reduced.
Beijing, Beijing MunicipalityAges 18–90 - NCT04441034RecruitingPhase 4
Compare two medicines for long-term pain in real life
This trial compares two types of medicines—anti-convulsants and anti-depressants—for people with persistent pain lasting more than 3 months. It aims to find out which option works better in everyday care and for which patients.
Redwood City, CaliforniaAges 18 years+ - NCT04451044Enrolling by invitation
Guided heart stent planning using an inside pressure sensor
This study tests whether using a tiny pressure sensor in heart arteries during a procedure can better guide where to place a stent. It may help doctors choose the safest and most effective stent plan by more accurately measuring artery narrowing.
Birmingham, AlabamaAges 18 years+ - NCT04312126Recruiting
How naps may improve motor learning after stroke or in healthy adults
This study tests whether taking a nap can improve how well people learn a movement task. It may help you understand how sleep affects “motor learning,” both in healthy volunteers and after stroke.
Bethesda, MarylandAges 18–80 - NCT04277416Enrolling by invitation
Testing a new hip replacement system and how patients do
This study follows people getting a primary total hip replacement using the Entrada hip system to see how long it lasts and how well it works. You may be offered this specific hip implant and would be followed through study visits to measure recovery and outcomes.
Portland, OregonAges 18–80 - NCT04373564RecruitingPhase 4
Tracking brain and movement changes after repeated MRI contrast
This study looks at whether getting the MRI contrast dye multiple times over 5 years affects body movement and thinking skills. It compares people who had the dye repeatedly with people who have little or no exposure, using brain MRI scans and regular mental and movement testing.
Scottsdale, ArizonaAges 18–64 - NCT04319042Recruiting
Same-day versus 4-week dental implant crown placement study
This study compares placing a crown on a dental implant either the same day as the implant or 4 weeks later. It may help decide which timing leads to better healing and tooth function after an implant.
Bern, Canton of BernAges 20 years+ - NCT04262492Recruiting
Registry of adults with APS on blood thinners
This study keeps an international registry of people with antiphospholipid syndrome (APS) who are taking direct oral blood thinners. It may help doctors better understand how APS patients do over time and improve future care, even if you’re not asked to change treatment.
NancyAges Any age - NCT04258774Enrolling by invitation
Breathing challenge during MRI to test brain blood-flow signals
This study uses a breathing challenge while you’re in an MRI to see how blood flow signals in the brain change. It may help researchers better understand how brain imaging signals respond to breathing and oxygen/carbon dioxide levels.
St Louis, MissouriAges 18 years+ - NCT04325958Recruiting
Test how cannabis affects driving in different age groups
This study looks at how smoked cannabis changes driving performance when compared across two age groups. It may help researchers understand safety risks and differences by age.
Toronto, OntarioAges 19–45
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,374 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.