Clinical trials
Effectiveness clinical trials
Below are recruiting effectiveness clinical trials, each written for real people, not researchers. We’re tracking 6,873 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05246267Recruiting
Dupilumab study for chronic sinus disease with nasal polyps
This study looks at how dupilumab (an injection medicine) helps people with chronic rhinosinusitis with nasal polyps, including how well it works across different ethnic backgrounds. You may be able to join if you’ve been diagnosed and you can get dupilumab through insurance or a patient assistance program.
The Bronx, New YorkAges 18–99 - NCT04936646Recruiting
Brain stimulation study for long-term nerve pain
This trial tests whether a form of brain stimulation (rTMS) can reduce chronic nerve pain that has lasted more than a year and hasn’t improved with standard treatments. It may help people whose usual pain medicines are stable but still not working well.
Grenoble, IsèreAges 18–80 - NCT05192759Recruiting
Theta-burst brain stimulation for walking freezing in Parkinson’s
This trial tests whether a specific type of noninvasive brain stimulation (theta-burst TMS) can improve “freezing of gait,” where walking suddenly stops. It may help by targeting brain circuits involved in movement, especially if your symptoms persist despite stable medication.
Hefei, AnhuiAges 40–85 - NCT05140525RecruitingPhase 3
BPA plus CTEPH medicines to improve heart strain
This trial tests whether starting specific medicines for CTEPH and then doing balloon pulmonary angioplasty (BPA) can improve how well the right side of the heart is working. It may help people who cannot have surgery (PTE) and are newly starting CTEPH/PAH-targeted treatment.
Durham, North CarolinaAges 18 years+ - NCT05071131Recruiting
Inulin supplement to improve gut health in kidney disease
This trial studies whether taking inulin—a dietary fiber—can improve gut bacteria and the gut barrier in people with end-stage kidney disease on hemodialysis. It may help reduce gut-related problems that can affect overall health in kidney disease.
BerlinAges 18–75 - NCT04757922Enrolling by invitation
Tests whether removing fallopian tubes affects menopause timing
This trial studies whether an “opportunistic salpingectomy” (removing fallopian tubes) during sterilization changes when menopause happens. It compares people who have this procedure to those who get different sterilization (tubal ligation) or none.
EindhovenAges 30–45 - NCT04734756Enrolling by invitation
Dragonfly device study for leaking mitral valve in high-risk patients
This trial tests the safety and effectiveness of a heart procedure that repairs a leaking mitral valve through thin tubes, using the Dragonfly system. It’s for people who have significant mitral valve leak symptoms but are considered high risk for open-heart surgery.
Hangzhou, ZhejiangAges 18 years+ - NCT04900597Recruiting
Testing blended tube feeds on kids’ stomach function
This study compares how “blended” tube feeds affect stomach and upper digestive function in children who use a feeding tube. It may help doctors understand whether blended feeds change digestion in ways that matter for comfort and physiology.
Boston, MassachusettsAges 1 year+ - NCT05107947Recruiting
Dynamic room lighting to improve sleep and daily body rhythm
This study tests whether changing the light in a hospital room can improve sleep and help your body clock work better in older adults. It may be most helpful if sleep problems or irregular daily rhythms are affecting you in the hospital.
MalmöAges 65 years+ - NCT05054829Recruiting
Social skills group for adults with autism
This trial tests whether a structured social skills training group can improve relationships for adults on the autism spectrum. It may help you practice real-life social situations with guided group support.
TaipeiAges 18–45 - NCT04938765RecruitingPhase 4
Magnesium before surgery to improve nerve monitoring
This trial tests whether giving a one-time magnesium dose (through an IV) before or during surgery changes how well doctors can monitor nerves while you’re under anesthesia. It may help make nerve monitoring more reliable during spine or brain operations.
Loma Linda, CaliforniaAges 18–80 - NCT04957355Recruiting
NMES therapy to improve balance and reduce falls after stroke
This trial tests whether NMES (a small electrical stimulation you feel on the skin) can improve balance and lower fall risk in people with stroke-related weakness. It may help you walk more steadily and safely, while the study measures balance and fall-related outcomes.
Chicago, IllinoisAges 18–90 - NCT05139719RecruitingPhase 2
HEC585 trial for slowing lung scarring decline
This Phase 2 study tests whether HEC585 can slow the decline in lung function in people with progressive fibrosing interstitial lung disease (PF-ILD). It may help preserve breathing capacity and breathing tolerance over time.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05136703Recruiting
Study depression treatment effects in people living with HIV
This study looks at how depression and its treatment may affect the brain and immune-related body systems in people with HIV. You may be eligible if you have depression and a well-controlled HIV viral load, and you can safely complete brain MRI scans.
Coral Gables, FloridaAges 18 years+ - NCT05205317Recruiting
VR alone or VR plus metformin for C-section scar healing
This study compares two treatments to help improve a C-section scar defect (an issue seen on the uterus scar). Some participants may receive virtual reality (VR) therapy plus metformin, while others receive VR alone, and the researchers will look at symptoms and scar healing.
Shanghai, Shanghai MunicipalityAges 18–40 - NCT04767659Recruiting
Optical imaging to predict full response to breast cancer chemo
This study uses a light-based scanner (optical imaging) during neoadjuvant chemotherapy to see how your breast cancer responds and to predict whether treatment will fully clear the tumor. If you qualify, it may help researchers better match imaging patterns to treatment success.
MilanAges 18 years+ - NCT05144035RecruitingPhase 4
Early growth-hormone treatment for small baby’s brain development
This study tests whether starting a growth hormone treatment early helps a baby’s thinking and learning development. It is for babies who are small for their gestational age and show delays on a developmental screening test.
Wuhan, WuhanAges 6 months–2 years - NCT05047133RecruitingPhase 2/Phase 3
Early TXA treatment for adult hip fracture surgery
This study tests whether giving a blood-clot-reducing medicine (TXA) early after an adult hip fracture helps reduce bleeding and related problems around surgery. It may help some patients getting operative fixation by improving safety during recovery.
Grand Blanc, MichiganAges 18 years+ - NCT05113017Recruiting
Radiation after surgery for early lung cancer you can’t remove
This trial studies whether a focused form of radiation called SBRT can safely treat remaining lung cancer nodules after surgery. It may help people whose leftover tumor spots can’t be removed by more surgery, aiming to control the cancer while limiting side effects.
Changsha, HunanAges 18–75 - NCT04858217Recruiting
Testing blood and joint fluid tests for hip or knee infection
This trial checks how accurate certain blood tests and joint-fluid (synovial) tests are at identifying infections around hip or knee replacements. It also looks at whether these tests are worth the cost, to help doctors choose the best next step.
BolognaAges 18 years+ - NCT05477849RecruitingPhase 1
Study drug for people with advanced solid tumors
This Phase 1 trial tests the safety and early effects of VG2025 in people with advanced solid cancers that have stopped responding to standard treatments. It’s mainly looking for side effects and how the body processes the drug, and it may offer a new option when other treatments haven’t worked.
Hangzhou, ZhejiangAges 18–75 - NCT03862924Recruiting
Study tests standardized e-cigarette effects in people with HIV who smoke
This study looks at how a specific e-cigarette affects health in people who have HIV and smoke cigarettes regularly. You might be able to join if you meet smoking, HIV care, and safety requirements and are not planning to quit right away.
Providence, Rhode IslandAges 18 years+ - NCT04533295Recruiting
Acupuncture to support pregnancy in women with failed IVF
This trial studies whether adding acupuncture during embryo transfer and hormone treatment can improve pregnancy outcomes for women who have had repeat IVF implantation failures with no known cause. It may help your chance of clinical pregnancy when you transfer good-quality frozen embryos.
Wuhan, HubeiAges 25–40 - NCT05738720Recruiting
Home breathing rehab to reduce COPD flare-ups and hospital visits
This trial tests whether a breathing and exercise program done at home can lower COPD flare-ups and the chance of needing hospital care. It may help people with more severe COPD manage breathlessness and stay stable.
IstanbulAges 18–75
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Common questions
- Are there clinical trials for effectiveness?
- Yes. Clin2 currently lists 6,873 recruiting effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.