Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,824 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07472491RecruitingPhase 2/Phase 3
Contrast MRI study for brain, spine, and body cancers
This trial tests a new contrast agent called mangaciclanol for MRI scans of the central nervous system (brain and spine) or body areas like the chest, belly, pelvis, and muscles. You may join if you have known or suspected tumors that need an MRI with contrast, and you're healthy enough to have two contrast MRIs within a short time.
Rochester, MinnesotaAges 18 years+ - NCT06630806RecruitingPhase 1
Study of an injection for relapsed or refractory myeloma
This trial tests a new injected drug for people with multiple myeloma that has returned or stopped responding to at least 3 prior treatments. The goal is to see if the drug is safe and works against the cancer.
Phoenix, ArizonaAges 18 years+ - NCT07333118RecruitingEarly Phase 1
Testing GT801 for severe autoimmune diseases
This trial tests a new treatment called GT801, a type of CAR-T cell therapy, for people with moderate to severe autoimmune diseases that have not responded to standard treatments. It aims to see if GT801 can safely and effectively control the disease.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT07693075RecruitingPhase 2
Radiotherapy for high-risk prostate cancer with boost to tumor
This trial tests a special type of radiation therapy that gives a higher dose to the tumor while treating the whole prostate. It is for men with high-risk or very high-risk prostate cancer that has not spread to distant organs.
CairoAges 18 years+ - NCT06628908RecruitingPhase 3
Study of suzetrigine for painful diabetic nerve damage
This trial tests an experimental medicine called suzetrigine to see if it can safely reduce pain caused by nerve damage from diabetes (diabetic peripheral neuropathy). It might be an option if you have had daily pain in both legs and current treatments haven't worked well enough.
Anniston, AlabamaAges 18–80 - NCT07458295Recruiting
Liposomal bupivacaine for pain after gynecologic cancer surgery
This trial tests whether a long-acting numbing medication (liposomal bupivacaine) injected into the abdominal wall can reduce pain after laparoscopic surgery for gynecologic cancer. If effective, it may help patients recover with less discomfort and fewer painkillers.
Beijing, Beijing MunicipalityAges 18–64 - NCT06972940Recruiting
Study of a gel to improve temple hollowing in Chinese adults
This trial tests a gel made from polycaprolactone (a safe, dissolvable material) to see if it can safely and effectively fill in hollow temples. It may be an option if you have flat or sunken temples and want a non-surgical treatment.
Beijing, Beijing MunicipalityAges 18–65 - NCT06141460RecruitingPhase 1/Phase 2
Gene therapy trial for wet age-related macular degeneration
This trial tests a new gene therapy called RRG001 for people with the 'wet' form of age-related macular degeneration. It aims to treat leaky blood vessels in the eye that can cause vision loss, possibly reducing the need for frequent eye injections.
Tianjin, Tianjin MunicipalityAges 50 years+ - NCT06150885RecruitingPhase 1/Phase 2
Study of CAR T Cells for Solid Tumors That Have Come Back
This trial tests a new type of immune cell (CAR T) made from healthy donors to fight solid tumors that have not responded to other treatments. It may be an option for people with certain cancers that show a protein called PD-L1.
Taichung, Non-USAges 18 years+ - NCT06243354RecruitingPhase 1/Phase 2
Study of HYP-2090PTSA for KRAS-mutated advanced solid tumors
This trial tests a new targeted pill called HYP-2090PTSA for people with advanced solid tumors that have a specific KRAS mutation. The goal is to see if the drug can shrink tumors or slow their growth.
Fuzhou, FujianAges 18 years+ - NCT07399769RecruitingPhase 1/Phase 2
MSLN CAR-T therapy for advanced solid tumors
This trial tests a new immune cell therapy called MSLN CAR-T for people with advanced solid tumors that have spread or cannot be removed by surgery. It may help if your cancer has not responded to standard treatment and tests positive for a protein called mesothelin (MSLN).
Shenzhen, Other (Non U.s.)Ages 18–75 - NCT06612645RecruitingPhase 1
CAR T cell therapy for children with solid tumors that returned
This trial tests a new type of immune therapy called CAR T cells designed to find and attack a protein called B7-H3 on solid tumor cells. It's for children and young adults whose cancer came back or didn't respond to standard treatment.
Bangkok, PathumwanAges 1–25 - NCT06610760RecruitingPhase 4
Ursodeoxycholic acid for stomach precancer reversal
This trial tests if ursodeoxycholic acid can reverse intestinal metaplasia (a precancerous stomach condition) in patients who have no H. pylori infection. The goal is to see if this medication can help lower the risk of stomach cancer.
Pingdingshan, HenanAges 18–75 - NCT07451431RecruitingPhase 4
Mirogabalin for diabetic nerve pain study
This study tests a new pain medicine called Mirogabalin for people with diabetic nerve pain that hasn't gotten better with usual treatments. It aims to see how well the drug works and if it is safe.
DhakaAges 40 years+ - NCT07389213Recruiting
Can brain stimulation and hearing aids slow memory loss in older adults with hearing loss?
This trial tests whether a non-invasive brain stimulation technique (rTMS) combined with hearing aids can help slow down thinking and memory decline in older adults who have age-related hearing loss.
Guangzhou, GuangdongAges 50–85 - NCT06639828RecruitingPhase 4
Safety study of Sonazoid for liver ultrasound in children
This trial tests a contrast agent called Sonazoid, which is used during an ultrasound to get clearer pictures of the liver. It is for children and teens who have one or more spots in the liver that need to be checked. The goal is to see if Sonazoid is safe and works well for children.
MünchenAges Up to 18 years - NCT06639256RecruitingPhase 1/Phase 2
Testing a new drug for advanced solid tumors
This trial is testing a new drug called HY07121 for people with advanced solid tumors that have not responded to standard treatments. The goal is to see if the drug is safe and effective.
JinanAges 18–80 - NCT06984406Recruiting
Beet product for kidney protection during heart procedure
This trial tests a beet-derived food product (a natural source of nitrate) to see if it can help prevent kidney damage caused by the contrast dye used during a heart procedure called PCI. It is designed for people who already have a higher risk of this kidney problem.
MoscowAges 18 years+ - NCT06447727Recruiting
Y-90 beads plus chemo for liver-only colorectal cancer
This trial tests whether adding radioactive Y-90 microspheres (tiny beads that deliver radiation directly to liver tumors) to standard chemo (FOLFIRI and bevacizumab) can help people with advanced colorectal cancer that has spread only to one lobe of the liver, when the first treatment stopped working. The goal is to slow down tumor growth.
Nanjing, JiangsuAges 18–75 - NCT06590259RecruitingPhase 2
Ablation plus drug therapy for colorectal cancer liver metastases
This trial tests a combination treatment that uses heat or cold (ablation) to destroy liver tumors along with medicines that boost your immune system to fight cancer. It is for people whose colorectal cancer has spread to the liver and who could not have surgery, or whose first treatment stopped working.
ShanghaiAges 18–75 - NCT07093866RecruitingPhase 2
Targeted drug combo for advanced prostate cancer
This trial tests a combination of two drugs—disitamab vedotin (a targeted antibody-drug that attacks HER2-positive cancer cells) and abiraterone (a hormone therapy)—to see if they can slow or shrink prostate cancer that has spread and become resistant to standard treatments.
Nanjing, JiangsuAges 18–75 - NCT07018947RecruitingPhase 2
Atezolizumab and bevacizumab before and after surgery for liver cancer
This trial tests whether adding two drugs (atezolizumab and bevacizumab) before and after surgery can lower the chance of liver cancer coming back in people with high-risk HCC. You must be eligible for surgical removal of your tumor.
Badalona, BarcelonaAges 18 years+ - NCT06588855RecruitingPhase 3
Study of afimkibart for moderate to severe ulcerative colitis
This trial is testing a new medication called afimkibart (RO7790121) for people with moderate to severe ulcerative colitis. It aims to see if this treatment can help reduce inflammation and improve symptoms in people who haven't had success with other therapies.
Dothan, AlabamaAges 16–80 - NCT06636552RecruitingPhase 2
Alternating drug combo plus daratumumab for newly diagnosed plasma cell leukemia
This trial tests a new treatment plan for people newly diagnosed with primary plasma cell leukemia (pPCL). It uses two different drug combinations that include daratumumab, given one after the other, followed by maintenance daratumumab. The goal is to see if this approach is safe and works well.
Athens, AtticaAges 18–80
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,824 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.