Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,733 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07260669RecruitingPhase 2
Vipoglanstat for endometriosis-related pelvic pain
This study tests an investigational drug called Vipoglanstat for women with endometriosis-related pelvic pain that happens even when they are not on their period. The goal is to see if it can reduce pain and improve quality of life.
BlagoevgradAges 18–44 - NCT07265284RecruitingPhase 3
IBI112 for teens with moderate to severe plaque psoriasis
This study tests a new medicine called IBI112 for teens aged 12–18 with moderate to severe plaque psoriasis. It aims to see if the medicine is safe and can help clear skin better than placebo.
Beijing, Beijing MunicipalityAges 12–18 - NCT07261644RecruitingPhase 3
Study of a new drug for active ankylosing spondylitis
This study tests a new medication (called 608) for adults with active ankylosing spondylitis (AS). It aims to see if the drug can reduce AS symptoms and improve quality of life.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07266181RecruitingPhase 1
CAR-T cell therapy for tough-to-treat membranous nephropathy
This trial tests whether specially engineered immune cells (CAR-T cells) can help people with a kidney condition called primary membranous nephropathy that has not improved with standard treatments. The goal is to see if this therapy can reduce protein in the urine and protect kidney function.
Xi'an, ChinaAges 18 years+ - NCT07266493RecruitingPhase 2
Envafolimab plus chemo for esophageal cancer before surgery
This trial tests a new immunotherapy drug (Envafolimab) combined with standard chemotherapy before surgery for esophageal cancer that has not spread far. The goal is to see if this combination can shrink tumors and improve outcomes.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07263230RecruitingPhase 2
Roflumilast Foam for Hidradenitis Suppurativa
This study tests whether roflumilast foam (a prescription foam) is safe and can reduce inflamed bumps in people with mild-to-moderate hidradenitis suppurativa (HS) who do not have draining tunnels. Participants will stop other HS treatments during the trial.
Boston, MassachusettsAges 18 years+ - NCT07263386RecruitingPhase 2
Immunotherapy plus chemo for PD-L1-positive stomach cancer
This trial tests whether adding the immunotherapy drug sintilimab to standard chemotherapy (SOX) after surgery helps prevent stomach cancer from returning. It’s for people whose tumors have a protein called PD-L1 and who had cancer in at least 7 lymph nodes.
Nanjing, JiangsuAges 18–75 - NCT07268521RecruitingPhase 2
Obinutuzumab for cryoglobulinemia vasculitis after rituximab failure
This trial tests if the drug obinutuzumab can help people with a blood vessel inflammation called cryoglobulinemia vasculitis when rituximab no longer works or causes side effects. It is a single-arm study, meaning everyone gets the new drug.
BloisAges 18 years+ - NCT07263425RecruitingPhase 2
Study of thiotepa and trastuzumab for breast cancer that spread to the lining of the brain and spinal cord
This trial tests a combination of two drugs given through a special port in the head to treat HER2-positive breast cancer that has spread to the layer covering the brain and spinal cord (leptomeningeal metastasis). It aims to see if this treatment is safe and effective.
Nanjing, JiangsuAges 18–75 - NCT07261501Recruiting
Antibacterial dressing for chronic wounds
This study tests a new absorbable wound dressing that fights bacteria to help heal chronic wounds that haven't improved for at least a week. It might be a good option if you have a wound that's infected or has bacteria on it and is between the size of a coin and a small plate.
Beijing, Beijing MunicipalityAges 1.5 years–80 years - NCT07266467RecruitingPhase 4
Preventing CMV After First Kidney Transplant
This trial tests a new medicine, Leymovir, against a standard one, Valganciclovir, to prevent a common virus infection (CMV) after a first kidney transplant. It may help you avoid CMV-related illness.
Xi'an, ShaanxiAges 18 years+ - NCT07269106RecruitingPhase 4
Testing anrikefon for pain relief after eye surgery
This trial tests a new painkiller called anrikefon for people having eye surgery under general anesthesia. It aims to see if it's safe and effective for controlling pain after the procedure.
Guangzhou, GuangdongAges 18–70 - NCT07262814RecruitingPhase 2
Testing arpraziquantel for liver fluke in children
This study tests if higher doses of arpraziquantel can safely treat children infected with the liver fluke Opisthorchis viverrini. It aims to find the best dose that clears the infection.
VientianeAges 6–7 - NCT06899399Recruiting
Stent study for asymptomatic carotid artery blockage
This trial tests a stent procedure to open a severely blocked carotid artery in people who have not had a stroke or mini-stroke from that blockage recently. It aims to see if the procedure is safe and effective for preventing future strokes.
BeijingAges 40–80 - NCT06221553RecruitingPhase 1
New CAR T-cell treatment for DIPG brain tumor
This trial tests a new type of immunotherapy called B7H3 IL-7Ra CAR T-cells for children with DIPG, a tough-to-treat brain tumor. The treatment is given directly into the fluid around the brain using a special catheter, and the goal is to see if it's safe and if it can help fight the tumor.
Bangkok, PathumwanAges 1–18 - NCT07256522Recruiting
Comparing treatments for trigger finger
This study compares three non-surgical treatments for a single trigger finger: a splint, paraffin wax, and a type of mud therapy. It aims to find which works best for improving finger movement and reducing pain.
Konya, KonyaAges 18–75 - NCT07256392Enrolling by invitationPhase 3
Long-term safety of barzolvolimab for chronic hives
This study is a long-term extension of the barzolvolimab trial for people with chronic spontaneous urticaria (CSU). It tests the continued safety and effectiveness of barzolvolimab over a longer period for those who have already completed the initial phase 3 study.
Birmingham, AlabamaAges 18 years+ - NCT07251309RecruitingPhase 3
Study of WS016 for treating high potassium levels
This trial tests a new drug called WS016 to lower high potassium levels in adults. High potassium can be dangerous for your heart, and this study aims to find out if WS016 is safe and effective.
Bengbu, AnhuiAges 18 years+ - NCT07252440RecruitingPhase 2
Testing an oral drug for early Alzheimer's disease
This study tests an oral tablet (TTYP01) for people with early Alzheimer's disease. It aims to see if the drug can slow memory loss. You must have a study partner who can support you throughout the trial.
Chongqing, Chongqing MunicipalityAges 55–85 - NCT07253259RecruitingEarly Phase 1
Cell therapy for hard-to-treat chronic graft-versus-host disease
This study tests a new cell therapy called GT729 for people with chronic graft-versus-host disease (cGVHD) that hasn't improved with at least two previous treatments. The therapy is given as an injection and aims to help control the immune system reaction that causes cGVHD.
Tianjin, Tianjin MunicipalityAges 18–65 - NCT07257887Recruiting
Testing OROXID oral solution for gum disease
This trial tests a mouth rinse (OROXID) to see if it helps treat advanced gum disease (periodontitis). You may qualify if you have at least three deep gum pockets and have not had dental cleanings or used antibiotics recently.
LjubljanaAges 18 years+ - NCT07251998RecruitingPhase 2
A study of ICP-332 for moderate to severe plaque psoriasis
This trial tests an oral medication called ICP-332 versus a placebo (a pill with no active drug) for people with moderate to severe plaque psoriasis. The goal is to see if ICP-332 can improve skin symptoms and be safe.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07251023RecruitingPhase 3
Testing a new drug for Alzheimer's dementia
This study tests whether a new drug called Latrepirdine (DMB-I) is safe and effective for people with mild to moderate Alzheimer's dementia. It may help slow cognitive decline when added to current treatment or used alone.
Kazan'Ages 60–90 - NCT07255534Recruiting
Digital therapy for shoulder recovery after rotator cuff repair
This trial tests a digital app-based therapy to improve shoulder function after rotator cuff repair surgery. It uses your smartphone to guide your rehabilitation exercises at home.
Seoul, Republic of KoreaAges 19 years+
Hear when a new Efficacy and Safety trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,733 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.