Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,733 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06909877RecruitingPhase 1/Phase 2
Study of HH2853 for relapsed or refractory peripheral T-cell lymphoma
This trial tests an experimental drug, HH2853, for people with certain types of T-cell lymphoma that have come back or not responded to prior treatments. It aims to see if the drug is safe and effective.
Chengdu, ChengduAges 18–75 - NCT06904872RecruitingPhase 2
Testing a diarrhea drug for short bowel syndrome without a colon
This trial tests if crofelemer can reduce diarrhea and fluid loss in people with short bowel syndrome who have a stoma (no colon connection) and need intravenous nutrition or fluids. The goal is to see if it improves gut function and quality of life.
AachenAges 18 years+ - NCT06911502RecruitingPhase 3
Golcadomide plus rituximab for relapsed follicular lymphoma
This trial tests a new drug, Golcadomide, combined with rituximab, for people with follicular lymphoma that has come back or hasn't responded to prior treatment. The goal is to see if this combination works better than other treatments your doctor might choose.
Birmingham, AlabamaAges 18 years+ - NCT05686759RecruitingPhase 3
Tested IV Hepabig in liver-transplant patients with hepatitis B
This Phase 3 study checks whether an undiluted IV infusion of I.V.-Hepabig inj is safe and works to help prevent hepatitis B from coming back after a liver transplant. It is mainly for adults who had a hepatitis B–related liver transplant and already received Hepabig regularly.
Goyang-si, Gyeonggi-doAges 18–64 - NCT06081647Recruiting
Testing a new airway device for endoscopy
This trial tests a special mouth-and-throat device designed to help you breathe easier during a routine endoscopy or colonoscopy. If you are a generally healthy adult scheduled for one of these procedures, you may be able to join.
Nanjing, JiangsuAges 18–60 - NCT06902896RecruitingPhase 1/Phase 2
FAP iCDC therapy for advanced heart failure from dilated cardiomyopathy
This trial tests a new treatment called FAP iCDC for people with end-stage dilated cardiomyopathy, a type of heart muscle disease. It aims to see if this therapy is safe and helps improve heart function when standard medicines are no longer enough.
Hangzhou, ZhejiangAges 18–75 - NCT06908668RecruitingPhase 2
Adebrelimab plus chemo with or without radiation before breast cancer surgery
This trial tests adding a drug called adebrelimab to standard chemotherapy and possibly radiation, given before surgery for breast cancer that is HER2-negative and locally advanced. The goal is to see if this combination helps shrink tumors more effectively, potentially allowing for breast-conserving surgery.
BeijingAges 18–70 - NCT05934383Recruiting
Ultrasound treatment to lower blood pressure after kidney transplant
This trial tests whether ultrasound “renal denervation” can safely and effectively lower blood pressure in people whose hypertension is not well controlled after a kidney transplant. If you qualify, the study may help you see whether this procedure reduces office and 24-hour blood pressure readings without harming your transplanted kidney.
RotterdamAges 18 years+ - NCT06732505RecruitingPhase 1
Ac-225 DOTATATE for SSTR+ GEP-NETs: A Safety Study
This trial tests a new drug, Ac-225 DOTATATE, in people with a type of gut or pancreas tumor (GEP-NET) that has specific proteins (SSTR) on its surface. The goal is to see if it is safe and helps shrink or slow the tumor.
Beijing, Beijing MunicipalityAges 18–80 - NCT06898983RecruitingPhase 2
Romiplostim for low platelets from leukemia treatment
This trial tests a drug called Romiplostim to help raise low platelet counts caused by leukemia treatment. It is for adults with leukemia whose platelets are below 50 and who may benefit from this therapy.
Hefei, AnhuiAges 18–75 - NCT06897839RecruitingPhase 2/Phase 3
Testing zelpultide alfa for preterm babies at risk of lung disease
This trial tests a medicine called zelpultide alfa in very premature babies who are at high risk of developing bronchopulmonary dysplasia (BPD), a chronic lung disease. The goal is to see if it can help prevent or lessen lung problems compared to standard care alone.
Buenos AiresAges birth–4 days - NCT06892548RecruitingPhase 1/Phase 2
Combination therapy for advanced lung cancer
This trial tests a new combination of two investigational drugs, BNT324 and BNT327, for people with advanced lung cancer that cannot be removed by surgery. It aims to see if the combination is safe and effective for different types of lung cancer, including non-small cell and small cell lung cancer.
Phoenix, ArizonaAges 18 years+ - NCT04467671RecruitingPhase 2
Tested new blood vessel graft for a heart surgery
This trial studies whether a newer “tissue-engineered” blood vessel graft is safe and works well in children who need a specific heart surgery connection outside the heart. It may help by offering a new type of graft, but your team will screen for size and medical factors first.
Columbus, OhioAges Any age - NCT06569953RecruitingPhase 4
Numbing Medicine for Pain After Lung Surgery
This study tests whether a long-lasting numbing medicine (liposomal bupivacaine) injected near the spine can better control pain after lung surgery. It compares this to a standard numbing medicine, and aims to help patients recover with less pain after surgery.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT06893783RecruitingPhase 2
Tarlatamab for advanced extrapulmonary neuroendocrine carcinoma
This study tests a drug called tarlatamab for people with a rare cancer called extrapulmonary neuroendocrine carcinoma that has grown or returned after standard chemotherapy. The goal is to see if tarlatamab can help shrink tumors and improve outcomes.
SeoulAges 19 years+ - NCT06892951RecruitingPhase 1/Phase 2
Inhaled caspofungin for treating pneumocystis pneumonia
This trial tests a new inhaled medicine (caspofungin) added to standard treatment for Pneumocystis pneumonia, a serious lung infection. It may help fight the infection more effectively while you are already receiving oxygen and standard antibiotics.
OrléansAges 18 years+ - NCT06900374Recruiting
Radiofrequency treatment for vaginal dryness in breast cancer patients
This trial tests if a gentle radiofrequency treatment can help breast cancer patients with vaginal dryness that hasn't improved with standard moisturizers. It aims to improve comfort and quality of life.
LilleAges 40 years+ - NCT06890494RecruitingEarly Phase 1
BiTE-EV for relapsed or hard-to-treat B-cell leukemia
This trial tests a new immunotherapy drug called BiTE-EV for people with B-cell acute lymphoblastic leukemia that has come back after treatment or is not responding well. The drug is designed to help your immune system find and kill cancer cells.
BeijingAges 18–70 - NCT06880042Enrolling by invitationEarly Phase 1
Narrowband UVB light therapy with tacrolimus or calcipotriol for vitiligo
This study compares two treatments for vitiligo: narrowband UVB light therapy combined with either tacrolimus ointment or calcipotriol ointment. It aims to see which combination works better and is safer for people with stable, limited vitiligo.
Lahore, Punjab ProvinceAges 15–70 - NCT06887192RecruitingPhase 2
Testing ML-007C-MA for Alzheimer's Psychosis
This trial tests a study drug called ML-007C-MA to see if it can safely reduce hallucinations and delusions in people with Alzheimer's disease who also have psychosis. If you or your loved one has Alzheimer's and has been experiencing false beliefs or seeing/hearing things that aren't there for at least two months, this study may be an option.
Phoenix, ArizonaAges 55–90 - NCT06880276RecruitingPhase 3
Studying QLM3003 ointment for mild or moderate eczema
This trial tests if an ointment called QLM3003 is safe and helps adults with mild to moderate atopic dermatitis (eczema). It may be a new treatment option for people whose eczema affects small areas of skin.
ShenyangAges 18–75 - NCT06883305RecruitingPhase 3
Testing tezepelumab for moderate to severe COPD
This trial tests tezepelumab, an injected medication, for people with moderate to very severe COPD who still have flare-ups despite using standard inhalers. It may help reduce flare-ups and improve breathing for those with higher eosinophil levels.
Foley, AlabamaAges 40–80 - NCT06880250Enrolling by invitation
Enzyme therapy study for Fabry disease patients
This trial tests if enzyme replacement therapy works well and is safe for Fabry disease. It is for people who are already prescribed this treatment.
AstrakhanAges 8–65 - NCT06882785RecruitingPhase 3
Testing KarXT for Japanese adults with schizophrenia
This trial tests a new medication called KarXT for people with schizophrenia who are currently having a psychotic episode. It is for Japanese adults who have had schizophrenia before and are not in their first episode.
Kōnan, Aichi-kenAges 18–65
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,733 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.