Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,799 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07208357Recruiting
Pregabalin with toludesvenlafaxine for fibromyalgia pain
This study tests a combination of two medications (pregabalin and toludesvenlafaxine) to see if it is safe and effective for people with fibromyalgia whose pain has not improved with non-drug treatments and who have not yet tried standard medications for this condition.
BeijingAges 18 years+ - NCT07208591RecruitingPhase 3
Test of an experimental drug for severe viral lung infection (ARDS)
This study tests an experimental drug (STSA-1002) for people with severe breathing problems caused by a viral infection. It aims to see if the drug can help improve oxygen levels and reduce the need for a breathing machine.
Beijing, Beijing MunicipalityAges 18–85 - NCT07211776RecruitingPhase 3
Study of ZL-1109 for active thyroid eye disease
This trial tests a new drug called ZL-1109 for people with active, moderate to severe thyroid eye disease (TED). It aims to see if the drug can reduce symptoms like bulging eyes and help patients feel better without using steroids.
BeijingAges 18–75 - NCT07212335RecruitingEarly Phase 1
Stem cells for low blood counts after CAR-T
This trial tests if umbilical cord stem cells can help restore low blood counts in people with leukemia, lymphoma, or myeloma who still have low blood cell levels three weeks after CAR-T therapy. It aims to improve recovery and reduce infection or bleeding risks.
TianjinAges 18 years+ - NCT07215416RecruitingPhase 1/Phase 2
Gene therapy for ataxia-telangiectasia with specific ATM mutation
This trial tests a new genetic medicine designed for people with A-T who have a specific ATM gene change. It aims to see if the treatment is safe and if it can improve symptoms.
Boston, MassachusettsAges birth–17 years - NCT07216014RecruitingPhase 4
IL-23 antibody for inflammatory bowel disease
This trial tests a new antibody drug (IL-23 inhibitor) for people with Crohn's disease or ulcerative colitis. It aims to see if the drug is safe and effective. You may be able to join if you have moderate to severe disease and have not had certain bowel surgeries or infections.
Guangzhou, GuangdongAges 18–65 - NCT07216430RecruitingPhase 2
Safety and efficacy of a pneumococcal vaccine in young kids
This study tests a new pneumococcal vaccine (wSp) in young children who have already had 3 doses of a standard pneumococcal shot. It aims to see if the new vaccine is safe and works well to protect against serious infections.
Pittsford, New YorkAges 5 months–7 months - NCT07216781RecruitingPhase 1
Klotho gene therapy safety trial
This trial tests a new gene therapy that uses a harmless piece of DNA (called a plasmid) to help your body make more Klotho, a protein linked to healthy aging. The goal is to see if it's safe and whether it might slow aging or improve health.
Austin, TexasAges 23–90 - NCT07218783RecruitingPhase 3
Testing a new glaucoma implant with cataract surgery
This trial tests a new implant that releases medicine for glaucoma while you have cataract surgery. It may help lower eye pressure without using daily drops.
Houston, TexasAges 22 years+ - NCT07218796RecruitingPhase 3
Bimatoprost implant with IOL vs. timolol drops for glaucoma
This trial tests if a bimatoprost implant placed during cataract surgery (combined with a special lens) can lower eye pressure better than standard timolol eye drops. It may help people with mild to moderate glaucoma or high eye pressure who are already planning cataract surgery.
San Antonio, TexasAges 22 years+ - NCT07221149RecruitingPhase 2/Phase 3
Pumitamig vs Nivolumab for untreated stomach or esophagus cancer
This trial compares two treatments for people with advanced stomach, gastroesophageal junction, or esophageal cancer that has not been treated before. One group gets pumitamig plus chemotherapy, the other gets nivolumab plus chemotherapy. The goal is to see which combination works better.
Phoenix, ArizonaAges 18 years+ - NCT07224763RecruitingPhase 1/Phase 2
Pig kidney transplant trial for kidney failure patients
This trial tests a genetically modified pig kidney (Thymokidney) for people with end-stage kidney disease who are on dialysis. It aims to see if this new type of transplant is safe and effective for those who cannot get a human kidney.
New York, New YorkAges 40–70 - NCT07225387RecruitingPhase 4
Belimumab and voclosporin for lupus kidney disease
This study tests whether combining two medications, belimumab and voclosporin, is safe and effective for treating a specific type of lupus that affects the kidneys (lupus nephritis). It may help people with active kidney inflammation who need better control of their disease.
Glendale, ArizonaAges 18–80 - NCT07229937RecruitingPhase 2
Testing an experimental drug for high cholesterol
This study tests an experimental drug called HRS-1301 to see if it safely lowers LDL ("bad") cholesterol in people with high cholesterol. It is for adults who either already have artery disease or are at higher risk for it.
Harbin, HeilongjiangAges 18 years+ - NCT07230171Recruiting
Short-term S-ketamine for fibromyalgia pain relief
This trial tests if low-dose S-ketamine, given as a short intravenous infusion, can safely improve fibromyalgia pain and other symptoms for people who haven't gotten enough relief from non-drug treatments. S-ketamine is a fast-acting medicine that blocks pain signals and may help reset how the brain processes pain.
BeijingAges 18 years+ - NCT07230197Recruiting
Pregabalin and dexmedetomidine for fibromyalgia pain
This trial tests whether combining two medications, pregabalin and dexmedetomidine, works better than standard treatments for fibromyalgia pain. It may help people with moderate to severe fibromyalgia who haven't found relief from non-drug therapies.
BeijingAges 18 years+ - NCT07230483RecruitingPhase 2
Long-term safety of CM512 for atopic dermatitis
This study is for people who have already completed a previous study of CM512 for atopic dermatitis. It will check if the medicine is safe and works well over a longer period.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07230730RecruitingPhase 3
Testing a new drug for high cholesterol
This trial tests a new medication called SHR-1918 for people with high cholesterol who are already on statins. The goal is to see if it can further lower cholesterol and improve health.
Hangzhou, ZhejiangAges 18 years+ - NCT07232433Recruiting
Freezing treatment for lung ground-glass nodules
This study tests a freezing treatment (cryoablation) for lung nodules that look like ground glass and are confirmed to be cancer. It's for people who cannot or choose not to have surgery or radiation.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07233239RecruitingPhase 1
CBD liquid for focal epilepsy seizures
This trial tests a new cannabidiol (CBD) liquid medicine for people with focal epilepsy (seizures that start in one part of the brain). It looks at whether the medication can help reduce seizures when added to your current seizure medications.
Phoenix, ArizonaAges 12–75 - NCT07237568RecruitingPhase 3
Testing LNK01001 for active ankylosing spondylitis
This trial tests a new oral medication called LNK01001 for adults with active ankylosing spondylitis. It aims to reduce pain, stiffness, and inflammation when standard NSAID treatments no longer help.
BeijingAges 18 years+ - NCT07239245RecruitingPhase 2
TACE plus immunotherapy for high-risk liver cancer before surgery
This trial tests whether a combination of two therapies—targeted chemotherapy delivered directly to the liver (TACE) plus immunotherapy (atezolizumab) and a targeted drug (bevacizumab)—can keep liver cancer from coming back after surgery. It is for people whose tumors can be surgically removed but are at high risk of recurrence.
Beijing, Beijing MunicipalityAges 18–75 - NCT07243626RecruitingPhase 2
Envafolimab plus chemo for advanced soft tissue sarcoma
This trial tests a new immunotherapy drug (envafolimab) combined with two chemotherapy drugs (doxorubicin and ifosfamide) for people with advanced soft tissue sarcoma who have not had prior treatment. The goal is to see if this combination is safe and effective.
Hanzhong, ZhejiangAges 18 years+ - NCT07244003RecruitingPhase 4
Testing metformin with two newer diabetes drugs
This trial is testing if adding a combination of SGLT-2 inhibitor and GLP-1 receptor agonist to metformin can improve blood sugar control in people with type 2 diabetes who are not meeting their goals on metformin alone or with one other pill.
Tianjin, Tianjin MunicipalityAges 18–75
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,799 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.