Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,799 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07437404RecruitingPhase 3
Testing SCT800 for previously untreated severe hemophilia A
This study tests a new medicine called SCT800 for boys with severe hemophilia A who have never been treated with factor VIII before. The goal is to see if it works safely to prevent bleeding.
Beijing, Beijing MunicipalityAges Up to 6 years - NCT07440537RecruitingPhase 2
Testing ICP-488 for active cutaneous lupus (skin lupus)
This trial tests an experimental drug called ICP-488 for people with active cutaneous lupus erythematosus (CLE), a type of lupus that affects the skin. It aims to see if the drug can reduce skin inflammation and improve symptoms.
Hefei, AnhuiAges 18–75 - NCT07441252RecruitingPhase 2
Study of maridebart cafraglutide for fatty liver with obesity
This trial tests a new medication (maridebart cafraglutide) to see if it can reduce fat in the liver and help with weight loss. It may be an option for adults with excess liver fat and obesity or overweight who haven't been able to lose weight with diet and exercise alone.
Chandler, ArizonaAges 18–99 - NCT07441720RecruitingPhase 2
Umbilical cord blood for low platelets after cancer therapy
This trial tests whether a one-time infusion of umbilical cord blood cells can safely raise platelet counts in people whose counts dropped after cancer treatment. It is for patients whose low platelets are clearly linked to their cancer therapy and who have no other major health problems.
Hangzhou, ZhejiangAges 12–65 - NCT07441902Recruiting
Numbing medicine for lung surgery pain relief
This trial tests whether a numbing medicine (liposomal bupivacaine) injected near the ribs can reduce pain after lung surgery. If you qualify, you may experience less pain and need fewer painkillers after your operation.
Beijing, Beijing MunicipalityAges 18–64 - NCT07442539Recruiting
Numbing medicine for pain after hemorrhoid surgery
This trial tests a long-acting numbing medicine called liposomal bupivacaine to see if it reduces pain after hemorrhoid surgery better than standard care. It may be an option for people who are otherwise healthy and scheduled for this surgery.
Beijing, Beijing MunicipalityAges 18–64 - NCT07444814RecruitingPhase 1
HWK-007 for advanced solid tumors
This trial tests a new drug called HWK-007, which is designed to target and attack cancer cells while sparing healthy ones. It is for people with specific advanced solid tumors (lung, endometrial, or ovarian cancer) that have not responded well to standard treatments.
Little Rock, ArkansasAges 18 years+ - NCT07446309RecruitingPhase 2
Comparing a new muscle relaxant to a standard one during surgery
This trial tests a new drug called HRS-9190 against a standard muscle relaxant (cisatracurium) given continuously through an IV during surgery. It aims to see if the new drug works as well and is safe for adults having planned surgery under general anesthesia.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07446491RecruitingPhase 1/Phase 2
PN20 for low platelets in liver disease patients needing a procedure
This study tests a new medicine called PN20 to safely raise platelet counts in people with chronic liver disease who need a minor procedure (like a biopsy). It's for patients whose platelet count is below 50 and whose liver disease is not too severe.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07447986RecruitingPhase 2
Testing a New Injection for Lupus (SLE)
This study tests a new injectable medicine (SG301) for people with lupus (SLE) whose current treatments are not working well enough or cause side effects. It aims to see if this targeted therapy can better control lupus symptoms.
Beijing, Beijing MunicipalityAges 18–70 - NCT07448285RecruitingPhase 3
Platelet-rich plasma injection for chronic shoulder pain
This trial tests whether injecting platelet-rich plasma (a concentration of your own blood cells that may help healing) can reduce chronic shoulder pain. It's for people whose pain hasn't improved with standard painkillers and who have a specific shoulder tendon condition.
Barakaldo, BizkaiaAges 35–75 - NCT07450547RecruitingPhase 2
A trial of a new medicine for cystic fibrosis and pancreatic problems
This trial tests a new medicine (ANG003) for people with cystic fibrosis who have severe pancreatic problems. It looks at how safe and effective the medicine is, and whether it helps with digestion.
Long Beach, CaliforniaAges 12 years+ - NCT07455188Recruiting
Switching targeted therapies for advanced HER2-positive breast cancer
This trial tests whether switching between two targeted therapy combinations can help women with HER2-positive advanced breast cancer that has progressed after previous treatments. It aims to find a new effective option for people who have already tried one or two lines of therapy.
Zhejiang, HangzhouAges 18 years+ - NCT07456033RecruitingPhase 3
Comparing a new asthma drug to placebo for type 2 asthma
This study tests if a new medication called depemokimab can reduce asthma attacks in people with type 2 asthma, a specific type of allergic asthma. Participants will get either the new drug or a placebo to see if it helps control their asthma better than standard treatments.
Newport Beach, CaliforniaAges 12 years+ - NCT07456696RecruitingPhase 3
TSND-201 for PTSD treatment study
This trial tests if an investigational drug called TSND-201 can help treat PTSD. It is for people who have tried at least one other PTSD treatment before.
Tucson, ArizonaAges 18 years+ - NCT07457528RecruitingPhase 2
Chemo, radiation, and immune therapy before surgery for esophageal cancer
This trial tests a combination of chemotherapy, radiation, and two targeted drugs (serplulimab and nimotuzumab) given before surgery for a certain type of esophageal cancer. It aims to see if this approach can safely improve outcomes.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT07463521RecruitingPhase 3
Study of rozanolixizumab for ocular myasthenia gravis
This study tests an investigational medication called rozanolixizumab for people who have ocular myasthenia gravis (MG), where weakness is only in the eye muscles. The medicine is given as an injection under the skin and may help improve symptoms like drooping eyelids or double vision.
Amherst, New YorkAges 18 years+ - NCT07463599RecruitingPhase 1/Phase 2
Tegavivint for advanced colorectal cancer after other treatments
This early-phase trial tests an experimental drug called tegavivint for people with advanced colorectal cancer who have already tried several standard treatments. It aims to see if the drug can shrink or slow the growth of tumors.
Scottsdale, ArizonaAges 18 years+ - NCT07464912RecruitingPhase 3
Testing TDI01 for idiopathic pulmonary fibrosis
This trial tests a new drug called TDI01 to see if it helps people with idiopathic pulmonary fibrosis (IPF), a lung disease that causes scarring. You may qualify if you have a confirmed IPF diagnosis and your lung function is stable enough.
Beijing, Beijing MunicipalityAges 40–80 - NCT07469683RecruitingPhase 2
Combination therapy for advanced kidney cancer after first-line treatment
This trial tests a combination of two drugs (SLC-3010 and axitinib) versus axitinib alone for people with advanced clear cell kidney cancer that has progressed after initial treatment. It aims to see if the combination is safer and more effective.
SeoulAges 19 years+ - NCT07469800RecruitingPhase 3
IBI362 for high blood pressure in overweight adults
This study tests an injectable medicine (IBI362) to see if it helps lower blood pressure in people who are overweight or have obesity. You may be eligible if you have high blood pressure but are not currently taking medication for it, and you do not have diabetes or major heart problems.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07470762RecruitingPhase 1/Phase 2
Study of HS-10542 for paroxysmal nocturnal hemoglobinuria (PNH)
This trial tests a new drug, HS-10542, for people with PNH who are already on a C5 inhibitor like eculizumab or covalizumab but still have low hemoglobin or need transfusions. It aims to see if this additional treatment can improve blood counts and reduce transfusion needs.
Hangzhou, ZhejiangAges 18–75 - NCT07470983RecruitingPhase 2
Study of HRS-1780 for Primary Aldosteronism
This trial tests a new drug called HRS-1780 for people with primary aldosteronism, a condition that causes high blood pressure. The goal is to see if the drug is safe and effective in lowering blood pressure and managing the condition.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT07471789RecruitingPhase 1/Phase 2
CART84 therapy for AML and T-ALL leukemia
This trial tests a new treatment called CART84 (GYA01) for patients with acute myeloid leukemia (AML) or T-cell acute lymphoblastic leukemia (T-ALL) that has come back or not responded to standard treatments. CART84 uses specially engineered immune cells to target and destroy leukemia cells that have a protein called CD84 on their surface.
Barcelona, BarcelonaAges 18 years+
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,799 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.