Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,799 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07565103RecruitingPhase 1/Phase 2
Testing SUM-191 eye drops for bacterial pink eye
This trial tests a new eye medication called SUM-191 for treating bacterial conjunctivitis (a bacterial infection that causes pink eye). The study has three parts: first testing safety in healthy people, then in people with the infection itself.
Austin, TexasAges 18 years+ - NCT02081755Enrolling by invitationPhase 4
Everolimus after liver transplant to lower liver cancer return
This trial studies whether everolimus, a transplant medicine, can safely reduce the chance that liver cancer comes back after liver transplant. It compares how well the treatment works while carefully monitoring side effects and safety.
San Francisco, CaliforniaAges 18 years+ - NCT07399704RecruitingPhase 2
Testing a new drug for two rare brain diseases
This trial is for people with Niemann-Pick type C or GM2 gangliosidosis who are already on or have been in a related study. It tests a new drug called Nizubaglustat to see if it is safe and works better than current treatments.
Água Verde, CuritibaAges 12 years+ - NCT07400952RecruitingPhase 2
Testing GLK-221 Eye Drops for Keratoconus
This study tests an eye drop called GLK-221 for people with keratoconus, a condition where the clear front of the eye bulges. The goal is to see if the drops can safely help improve the condition compared to a placebo (an inactive solution).
Westerville, OhioAges 18–55 - NCT07401537RecruitingPhase 2
Comparing two schedules of immunotherapy for advanced triple-negative breast cancer
This trial tests whether giving immunotherapy less often (extended dose intervals) works as well as the standard schedule for people with advanced triple-negative breast cancer who have already completed 6 cycles of first-line treatment. It aims to see if a longer break between doses can be just as effective with fewer hospital visits.
Guangzhou, GuangdongAges 18–70 - NCT07404891Recruiting
Study of ALT001 for knee osteoarthritis pain
This study tests whether a new medicine (ALT001) can safely reduce knee pain from osteoarthritis. If you join, you would stop your current pain medicines and take the study drug or a placebo for a set time, while being closely monitored.
Wuhan, HubeiAges 50–75 - NCT07405216RecruitingPhase 4
SGLT2 inhibitors for teens with early kidney disease
This trial tests whether a type of medicine called SGLT2 inhibitors can help teenagers with early-stage chronic kidney disease. It looks at how safe and effective these drugs are for slowing down kidney damage.
Aguascalientes, AguascalientesAges 14–18 - NCT07406152Recruiting
A gel for hard-to-heal chronic wounds
This study tests a new gel and applicator for chronic wounds that are hard to heal, like bed sores, diabetic foot ulcers, and leg ulcers. The goal is to see if the gel helps wounds heal safely.
Vitoria-Gasteiz, ÁlavaAges 18 years+ - NCT07406932Recruiting
JAK inhibitors vs standard therapy for lung scarring in Anti-Synthetase Syndrome
This trial tests whether a new class of drugs called JAK inhibitors (which block inflammation signals) is better than a standard treatment (calcineurin inhibitors) for people with lung scarring (interstitial lung disease) caused by Anti-Synthetase Syndrome. It is for people who have not yet taken any immune-suppressing medications for this condition.
Beijing, Beijing MunicipalityAges 18–75 - NCT07406945Recruiting
Testing a new tool during POEM for swallowing problems
This trial tests a new tool (SpydrBlade) during a procedure called POEM to help people with swallowing problems like achalasia. The goal is to see if it's safe and works well.
GuayaquilAges 18 years+ - NCT07408024RecruitingPhase 2
TollB-001 tablets for moderate to severe rheumatoid arthritis
This trial tests an experimental tablet, TollB-001, for people with moderate to severe rheumatoid arthritis who have not responded well to standard treatments. The goal is to see if the drug is safe and effective.
Bengbu, AnhuiAges 18–70 - NCT07410364Recruiting
CAG and PCI via distal wrist access for small vessels
This trial tests whether a new wrist access point (the distal radial artery) along with specific drug treatments (CAG and PCI) is safe and effective for people with small blood vessels in the heart. It aims to offer an alternative that may reduce bleeding or damage risks.
Changzhou, JiangsuAges 18–85 - NCT07413094RecruitingPhase 2
Testing a new drug for sepsis-related lung injury
This trial tests a new medicine called YD0743 for people who have both sepsis (a serious infection) and ARDS (a severe lung injury from the infection). The goal is to see if the medicine helps improve breathing and survival.
BeijingAges 18–75 - NCT07413835Recruiting
Study of HN2302 for hard-to-treat myasthenia gravis
This trial tests a new medicine called HN2302 for people with generalized myasthenia gravis (MG) that hasn't improved with standard treatments. It aims to see if HN2302 is safe and helps reduce muscle weakness symptoms.
Xuzhou, JiangsuAges 18–80 - NCT07414342Recruiting
Study of RENATUS® valve for severe aortic stenosis
This study tests a new device called the RENATUS® Transcatheter Aortic Valve System for people with severe aortic stenosis. It is designed to replace the narrowed valve without open-heart surgery, and aims to see if it is safe and effective for patients with various surgical risk levels.
BeijingAges 60–100 - NCT07418112RecruitingPhase 4
Laser vs other device for hard bile or pancreas stones
This study compares two types of lithotripsy (stone-breaking) devices, holmium laser and electrohydraulic lithotripsy, for treating difficult stones in the bile or pancreatic ducts. If you have a bile or pancreas stone that is large, stuck, or could not be removed with standard procedures, this trial may help determine which method works best.
Chicago, IllinoisAges 19–85 - NCT07418190RecruitingPhase 2
Combination therapy for relapsed follicular lymphoma
This trial tests a combination of three targeted drugs (zanubrutinib, rituximab, lenalidomide) plus an immunotherapy drug (tislelizumab) for people with follicular lymphoma that has returned or not responded to at least two prior treatments. The goal is to see if this combination is safe and effective.
Nanjing, JiangsuAges 18–75 - NCT07423013Recruiting
Teprotumumab treatment for active thyroid eye disease
This trial tests a new version of an antibody treatment (teprotumumab) for people with active thyroid eye disease. It aims to reduce bulging and inflammation of the eyes, and you must have had symptoms for less than 9 months to join.
BeijingAges 18–80 - NCT07423390RecruitingPhase 3
Vitamin B12 to prevent nerve damage from chemo
This trial tests if taking mecobalamin (a form of vitamin B12) can prevent or reduce nerve pain and numbness caused by taxane chemotherapy. It may help people getting chemo for several types of cancer.
Xining, QinghaiAges 18 years+ - NCT07423533RecruitingPhase 2
GenSci120 injection for moderate to severe rheumatoid arthritis
This trial tests a new injection called GenSci120 for people with moderate to severe rheumatoid arthritis who haven't improved enough after trying at least one standard arthritis medication. The goal is to see if this treatment can help reduce joint pain and swelling.
Beijing, Beijing MunicipalityAges 18–70 - NCT07426120RecruitingPhase 3
Coumarin cream for psoriasis: a research study
This study tests a cream made from a natural plant compound (coumarin) to see if it can help treat plaque psoriasis. If you have mild-to-moderate psoriasis and haven't used certain other treatments recently, this trial may be an option for you.
New York, New YorkAges 18–70 - NCT07432711Recruiting
Liposomal bupivacaine for pain after lung surgery
This trial tests if a long-acting numbing medicine called liposomal bupivacaine can reduce pain after video-assisted lung surgery. It aims to help patients feel better after the procedure with less need for other painkillers.
Beijing, Beijing MunicipalityAges 18–64 - NCT07434518Recruiting
Study of adebrelimab for advanced small cell lung cancer
This study looks at how well adebrelimab works and how safe it is in real-world settings for people with advanced small cell lung cancer that has spread. It may help doctors understand if this treatment is a good option for patients like you.
ShanghaiAges 18–100 - NCT07435142Recruiting
Urine-derived cells for corneal eye disease
This trial tests if using special cells from your own urine can help repair the inner layer of your cornea (the clear front part of your eye). It may be an option if you have damage to these cells and have already had at least one cornea transplant.
Jinan, ShandongAges 18–85
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,799 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.