Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,799 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07522242RecruitingPhase 2
Eye Drops to Slow Nearsightedness in Children
This study tests a new eye drop medicine (T10430) to see if it can slow down how fast children's nearsightedness gets worse. The trial will measure whether the drops are safe and effective for kids ages 6–11.
AmmanAges 6–11 - NCT07523308Recruiting
Minimally invasive surgery for bowel endometriosis
This trial tests a new surgical approach using small incisions and cameras to treat endometriosis affecting the bowel. The goal is to improve bowel function and quality of life for women with this painful condition.
Shanghai, Shanghai MunicipalityAges 18–55 - NCT07523971Recruiting
Pitavastatin/Ezetimibe for High Cholesterol and Metabolic Syndrome
This study watches how well a combination cholesterol medication (pitavastatin and ezetimibe) works in people who have high cholesterol and metabolic syndrome (a cluster of health issues including high blood pressure, blood sugar, and cholesterol). You'll be monitored over time to see if the medication helps and is safe for you.
DaejeonAges 19 years+ - NCT07525869Recruiting
Pegfilgrastim to prevent low white blood cells in triple-negative breast cancer
This study tests whether a medicine called pegfilgrastim can help prevent dangerously low white blood cell counts in women with triple-negative breast cancer receiving a specific chemotherapy combination. Low white blood cells increase infection risk, so this medicine may help patients stay safer during treatment.
Seoul, Seodaemun-guAges 19–70 - NCT07529782RecruitingPhase 1
Safety and Efficacy of HDP-101 in Relapsed or Refractory Multiple Myeloma
This trial tests a new drug called HDP-101 in patients with multiple myeloma that has come back or stopped responding to previous treatments. The study aims to find the safest and most effective dose and to see if this drug can help control the cancer.
Beijing, Beijing MunicipalityAges Up to 18 years - NCT07530705RecruitingPhase 1/Phase 2
XH-02 Injection for Low Parathyroid Hormone Levels
This study tests whether a new injectable medicine called XH-02 can safely treat hypoparathyroidism—a condition where your body doesn't make enough parathyroid hormone, causing low calcium levels. If your calcium isn't well-controlled with current treatments (calcium and vitamin D supplements), this trial might help.
Beijing, Beijing MunicipalityAges 18–65 - NCT07532486Recruiting
Guselkumab dosing study for moderate-to-severe psoriasis
This study tests whether a higher dose of guselkumab (a biologic medicine) given less frequently works as well as the standard dose for treating moderate-to-severe plaque psoriasis. The goal is to find a dosing schedule that is both effective and convenient for patients.
Hangzhou, ZhejiangAges 18 years+ - NCT07536113Recruiting
Blood Test to Guide Second Colorectal Cancer Treatment
This study looks at whether a simple blood test can help doctors decide if you should receive a specific type of cancer drug again. The blood test looks for cancer DNA to predict if the drug will work for your advanced colorectal cancer.
Milan, ItaliaAges 18 years+ - NCT07536750Recruiting
Comparing Two Sedation Drugs for ICU Patients on Breathing Support
This study compares two medications (ciprofol and propofol) used to keep ICU patients calm and comfortable while they receive non-invasive breathing support, such as oxygen masks or tubes that help them breathe without a breathing tube in their windpipe. Researchers want to see which drug works better and is safer.
Guangzhou, GuangdongAges 18 years+ - NCT07537361RecruitingPhase 2
Leucine-Restricted Diet With Chemotherapy for Gastric Cancer
This trial tests whether a special diet low in leucine (an amino acid) combined with chemotherapy and immunotherapy drugs can help treat locally advanced gastric cancer before surgery. The goal is to see if this combination is safe and more effective than standard treatment alone.
Jinan, ShandongAges 18–70 - NCT07539792RecruitingPhase 2
New Skull Support Plates for Pituitary Tumor Surgery
This study tests a new type of absorbable (dissolvable) support plate used during minimally invasive surgery to remove tumors in the pituitary gland area. The plate helps support the surgical site as it heals. Researchers want to see if this new plate works safely and effectively compared to standard approaches.
Foshan, GuangdongAges 1–80 - NCT07539805RecruitingPhase 2
Sertraline Plus Probiotic for Teen Depression
This study tests whether combining sertraline (an antidepressant) with a specific probiotic called Lactobacillus crispatus can safely and effectively treat depression in teenagers. The probiotic may help by improving gut health, which researchers believe could support mental health.
Longgang, Chongqing MunicipalityAges 12–18 - NCT07540286RecruitingPhase 2
Study of XH-02 for Treating Low Parathyroid Hormone Levels
This study tests a new drug called XH-02 for hypoparathyroidism—a condition where your body doesn't make enough parathyroid hormone, causing low calcium levels. If you haven't improved with standard calcium and vitamin D treatments, this trial may help.
BeijingAges 18–90 - NCT07540741Recruiting
PCSK9 Inhibitors for Large-Artery Stroke Recovery
This trial tests whether a cholesterol-lowering medication called evolocumab (a PCSK9 inhibitor) can help people recover better after a specific type of stroke caused by clogged arteries. The study checks if lowering cholesterol further than usual statins do improves stroke outcomes and is safe.
HeilongjiangAges 18–80 - NCT07546383Recruiting
New Immunotherapy Combination for Advanced Head and Neck Cancer
This trial tests a new combination of two immunotherapy drugs (called iparomlimab and tuvonralimab), with or without chemotherapy, for head and neck squamous cell carcinoma that has returned or spread after previous treatment. The goal is to see if this combination can help people with this cancer live longer with fewer side effects.
Haikou, HainanAges 18–75 - NCT07547553RecruitingPhase 1/Phase 2
HH-009 for Advanced Liver Cancer with FGF19 Marker
This trial tests a new drug called HH-009 for advanced or inoperable liver cancer (hepatocellular carcinoma, or HCC) that has a specific genetic marker called FGF19. The drug is designed to target this marker and may help slow or shrink the cancer in people whose disease has gotten worse despite previous treatment.
Bengbu, AnhuiAges 18–75 - NCT07551037RecruitingPhase 1
Immune Therapy to Prevent AML Relapse After Chemotherapy
This trial tests a new type of maintenance therapy for acute myeloid leukemia (AML) patients who have already responded well to chemotherapy. The treatment uses your own immune cells to help prevent the cancer from coming back.
Fuzhou, FujianAges 18–70 - NCT07551492RecruitingPhase 3
Testing HRS9531 for heart and blood vessel disease
This study tests whether a new drug called HRS9531 can help people with atherosclerotic cardiovascular disease (hardened arteries affecting the heart and blood vessels). The trial will check if it's safe and effective for managing this condition.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07552012RecruitingPhase 2
FXS5626 for Non-Infectious Eye Inflammation
This trial tests a new drug called FXS5626 to treat non-infectious uveitis—inflammation inside the eye that doesn't come from infection. The study looks at whether this drug can reduce eye inflammation and improve vision in people whose condition isn't controlled with steroid eye drops and oral steroids alone.
Chongqing, Chongqing MunicipalityAges 18–70 - NCT07552077RecruitingPhase 2
Sirolimus Gel for Angiokeratoma Treatment
This trial tests a topical gel (a cream you apply to skin) containing sirolimus to treat angiokeratomas, which are small growths on the skin. The goal is to see if this treatment is safe and effective.
Sherman Oaks, CaliforniaAges 6 years+ - NCT07552389RecruitingPhase 3
Blood Pressure and Diabetes Combination Drug Trial
This study tests whether taking two separate blood pressure medications work as well as taking them combined in one pill for people with high blood pressure and type 2 diabetes. The goal is to find the best, safest way to treat both conditions together.
SeoulAges 19 years+ - NCT07556757RecruitingPhase 1
CD-19 T-cell therapy for relapsed B-cell leukemia in teens and adults
This study tests a new engineered cell therapy (CD-19 t-haNK) designed to fight back B-cell acute lymphoblastic leukemia (a blood cancer) in patients whose cancer has returned or stopped responding to standard treatment. The therapy uses specially modified immune cells to target and destroy leukemia cells.
JohannesburgAges 12 years+ - NCT07559370RecruitingPhase 2
Imatinib Plus Artemether-Lumefantrine for Uncomplicated Malaria
This trial tests whether adding a cancer drug called imatinib to standard malaria treatment works better and is safe. Researchers will enroll adults and children with uncomplicated malaria caused by P. falciparum parasites and monitor them in the hospital for 2–3 days.
KisumuAges 1–55 - NCT07562282Recruiting
Medication combinations for kidney stone stent discomfort
This trial tests two different doses of medications (tamsulosin and tadalafil) to help with pain and discomfort from a plastic tube (called a DJ stent) placed in your kidney after stone removal surgery. The goal is to find which dose combination works best and is safest.
Cairo, AbbasiaAges 18–71
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,799 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.