Clinical trials
Epilepsy clinical trials
Below are recruiting epilepsy clinical trials, each written for real people, not researchers. We’re tracking 339 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07445074Recruiting
AI phone app to help teens and young adults with epilepsy take their medicine
This study tests a mobile app that uses artificial intelligence to help people with epilepsy remember to take their anti-seizure medication. It is for teens and young adults (ages 14-24) living in Florida who are from underserved communities.
Orlando, FloridaAges 14–24 - NCT07460037Recruiting
Brain signal study for speech recovery after stroke or injury
This trial uses a special brain-mapping test called high-density ECoG to study how people who have lost speech due to stroke, brain tumor, or ALS can be helped by reading brain signals when they imagine speaking. It may lead to new devices that let people with severe speech problems communicate using only their thoughts.
Hangzhou, ZhejiangAges 20–80 - NCT07544563Recruiting
Brain Activity During Sound Testing
This study measures how your brain responds to sounds in a specially designed quiet room. Researchers want to understand how epilepsy affects sound processing, which could help improve treatment in the future.
ParisAges 18 years+ - NCT07594158RecruitingPhase 3
ONO-2017 for Seizures in Japanese Children and Teens
This study tests a new seizure medication called ONO-2017 in Japanese children and teenagers (ages 2–17) who have a specific type of seizure called POS that hasn't been controlled by current medicines. The goal is to see if this new drug is safe and helps reduce these seizures.
FukuokaAges 2–17 - NCT07605858Recruiting
Epilepsy, Sleep, and Brain Activity Study
This study examines how seizures affect sleep quality and dreams in people with hard-to-treat focal epilepsy. Researchers will use specialized brain electrodes to understand these connections during sleep, which may help improve treatment in the future.
Durham, North CarolinaAges 18–55 - NCT07663578Recruiting
Brain stimulation study for epilepsy patients and healthy volunteers
This study tests a new non-invasive brain stimulation method called TIEFS. It uses safe electric fields to see how it affects thinking and brain waves. You may join if you are having brain surgery for epilepsy or are a healthy adult.
Sacramento, CaliforniaAges 18–65 - NCT07595666Enrolling by invitation
New PET scanner versus standard PET for head and neck imaging
This study compares a newer PET/CT scanner (called NeuroEXPLORER) with standard PET/CT scanners for imaging the head and neck region. The goal is to see if the new scanner provides better or clearer images to help diagnose conditions.
Leuven, Vlaams-BrabantAges 4 weeks+ - NCT07454785Enrolling by invitation
How the brain learns new patterns
This study looks at how the brain learns and uses patterns. If you have epilepsy that requires brain monitoring, you may be able to join and help researchers understand memory and thinking.
Los Angeles, CaliforniaAges 18 years+ - NCT07226908Enrolling by invitation
Brain electrode study for epilepsy and memory
This study places electrodes in the brain to learn how seizures spread and how memory works. It may help people with temporal lobe epilepsy understand their condition better and improve future treatments.
Stanford, CaliforniaAges 18–65 - NCT06762743Enrolling by invitationPhase 1
Comparing two brivaracetam oral solutions in healthy adults
This study tests whether two different forms of an oral solution of brivaracetam (a seizure medication) have the same effect in the body. Healthy adults take one dose and have blood samples collected—first on an empty stomach, and later after a high-fat meal—to compare how the drug is absorbed.
Nanjing, JiangsuAges 18–55 - NCT06583395Enrolling by invitation
Meditation retreat study with fitness tracker
This trial studies people attending a 7-day meditation retreat to see how meditation affects well-being. You will wear a fitness tracker and answer surveys.
Palm Desert, CaliforniaAges 21 years+ - NCT06489561Enrolling by invitation
Brain activity study for epilepsy patients
This study looks at how your brain makes decisions. It involves pressing buttons on a laptop while your brain activity is recorded. The goal is to understand how the brain works in people with epilepsy.
Los Angeles, CaliforniaAges 18–65 - NCT06443463Enrolling by invitationPhase 2
Long-term safety of BHV-7000 in epilepsy
This study checks the long-term safety of BHV-7000 for people who already completed an earlier trial with this drug. You keep taking the same medicine while doctors watch for any side effects over time.
Birmingham, AlabamaAges 18–75 - NCT06391294Enrolling by invitation
Brain stimulation study for language mapping during awake surgery
This study uses gentle electrical stimulation on the brain during awake surgery to understand how language works. It's for people having brain tumor removal or epilepsy monitoring who can speak English and do not have serious speech or thinking problems.
Chicago, IllinoisAges 18–80 - NCT06252532Enrolling by invitation
Brain wave study for epilepsy with electrodes
This research study looks at how certain brain waves (called theta oscillations) help you focus and prioritize information. If you have epilepsy that hasn't been controlled with medicines and you already have brain electrodes in place for your epilepsy monitoring, you may be able to join this study to help scientists understand the role of these brain signals.
Chapel Hill, North CarolinaAges 18–80 - NCT06144957Enrolling by invitation
SLC13A5 deficiency natural history study (US only)
This study follows people with SLC13A5 deficiency (a rare genetic condition that affects brain development) to learn more about the disease over time. It collects health information, assessments, and samples to help understand the condition and plan future treatments.
Palo Alto, CaliforniaAges Any age - NCT06138808Enrolling by invitation
5-sense score validation for epilepsy surgery
This study is for people with epilepsy who are being considered for brain surgery but cannot have a direct surgical approach. It tests a new scoring method (5-SENSE) that uses non-invasive tests like MRI and EEG to see if it can help doctors make better surgery decisions.
Gainesville, FloridaAges 15 years+ - NCT05876910Enrolling by invitation
Study brain signals for stopping speech during epilepsy care
This study looks at how the brain helps stop ongoing speech. It may help researchers understand brain control during medication-resistant epilepsy surgery, using recordings from implanted electrodes.
San Francisco, CaliforniaAges 18–65 - NCT05450237Enrolling by invitation
Testing thinking and memory questionnaires in people with brain injury
This study checks how well certain questionnaire and testing tools work for people who have brain damage from neurologic conditions and ongoing brain inflammation. It may help future patients by improving which tests are most accurate and easy to use.
Pozzilli, IserniaAges 18–80 - NCT05435859Enrolling by invitation
Mapping the brain area for speech during surgery
This study uses tiny brain electrodes placed during surgery to better understand how a brain region helps with speech. The results may guide safer brain mapping during surgery for people with epilepsy or brain tumors.
San Francisco, CaliforniaAges 18–70 - NCT05380921Enrolling by invitation
Dry-electrode EEG headset for VA telehealth visits
This trial is testing a new “dry electrode” EEG headset used during EEG testing done as an outpatient (and possibly from home/clinic by telehealth). It may help make EEG recordings easier and more comfortable compared with traditional setups.
Miami, FloridaAges 18 years+ - NCT05152992Enrolling by invitation
Studying brain networks during epilepsy surgery planning
This study looks at how emotion-related brain connections change in space and over time while people with epilepsy are having surgery-related electrodes placed to find seizure sources. It may help researchers better understand brain networks and improve future treatment planning.
San Francisco, CaliforniaAges 18–80 - NCT05014841Enrolling by invitation
Brain electrode study of speech across different languages
This study uses electrodes placed on the brain during surgery to understand how speech is represented in different languages. It may help doctors better map language areas and improve surgical planning for people having brain surgery.
San Francisco, CaliforniaAges 18–70 - NCT04681781Enrolling by invitation
Remote study of SLC13A5 deficiency history
This study follows people with SLC13A5 deficiency to better understand how the condition changes over time, using surveys and clinical check-ins done remotely. If you (or your child) have this genetic condition, it may help researchers learn what symptoms to expect and how to track them.
Palo Alto, CaliforniaAges Any age
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Common questions
- Are there clinical trials for epilepsy?
- Yes. Clin2 currently lists 339 recruiting epilepsy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a epilepsy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a epilepsy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.