Clinical trials
Epilepsy clinical trials
Below are recruiting epilepsy clinical trials, each written for real people, not researchers. We’re tracking 328 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07318870RecruitingPhase 2
Probenecid for reducing seizure clusters during hospital epilepsy monitoring
This trial tests whether a drug called probenecid can help reduce the number of seizures that happen in a cluster during a hospital stay when your seizure medications are being reduced to record your seizures. The goal is to see if giving probenecid can make the monitoring period safer and more effective for people with focal epilepsy being evaluated for surgery.
ParisAges 6–50 - NCT07288788Recruiting
Kidney function in children with epilepsy
This study looks at how well the kidneys work in children who have epilepsy. It may help doctors understand how epilepsy or its treatment affects kidney health.
SohagAges 1 month–15 years - NCT07287163Enrolling by invitationPhase 3
Long-term study of vormatrigine for epilepsy
This trial is for adults with epilepsy who have already taken vormatrigine in a previous study or through a special access program. It aims to collect ongoing safety and effectiveness information.
Miami, FloridaAges 18–85 - NCT07271966Recruiting
Vitamin B6 for Keppra side effects in brain tumor patients
This trial tests whether vitamin B6 can help reduce mood and behavior side effects of levetiracetam (Keppra) in people with brain tumors and seizures. If you're taking Keppra and feeling down or distressed, this study might offer a way to feel better.
Durham, North CarolinaAges 18 years+ - NCT07253701Recruiting
Epilepsy and gut bacteria: understanding treatment response
This study looks at how the bacteria in your gut relate to how well epilepsy treatments work. It compares people with newly diagnosed epilepsy (who haven't yet started medicine) to healthy people without epilepsy.
GothenburgAges 2–79 - NCT07244328RecruitingEarly Phase 1
UX-GIP001 cell therapy for drug-resistant temporal lobe epilepsy
This trial tests a new cell therapy, UX-GIP001, for people whose seizures start in one small area of the brain (the mesial temporal lobe) and are not controlled by at least two seizure medications. The goal is to see if this treatment can safely reduce seizures.
Hangzhou, ZhejiangAges 18–75 - NCT07238868RecruitingPhase 2
Long-term safety study of CB03-154 for epilepsy
This study is a long-term follow-up for people with epilepsy who already completed a previous trial of the drug CB03-154. It checks if the drug remains safe and effective over more time.
Melbourne, VictoriaAges 18–70 - NCT06263920Recruiting
Study on late-onset epilepsy and its links
This study looks at people who had their first seizure or were diagnosed with epilepsy after age 18, and compares them to people with migraine. The goal is to understand what might be connected to epilepsy that starts later in life.
Preston, LancashireAges 18 years+ - NCT07202494Recruiting
Brain aging and resilience MRI study
This study uses powerful MRI scans to understand how the brain ages and why some people stay healthy while others develop neurological diseases like multiple sclerosis or Alzheimer's. It compares healthy volunteers to people with certain conditions, and all participants get a detailed brain MRI.
MarseilleAges 18–90 - NCT07193277RecruitingPhase 4
Butylphthalide for thinking problems in older adults with epilepsy
This study tests whether a medicine called butylphthalide can help improve memory and thinking in older adults with focal epilepsy who already have mild cognitive issues. It aims to find a new way to support brain health in people with epilepsy.
Wenzhou, ZhejiangAges 60–85 - NCT07145489Recruiting
Infrared light therapy for seizures
This trial tests whether shining a special infrared light on the scalp can reduce seizures in adults with epilepsy that is not controlled by standard medications. You would receive the light treatments and keep a diary of your seizures.
Boston, MassachusettsAges 18 years+ - NCT07147309Recruiting
PET scans for epilepsy surgery planning
This trial tests three types of PET scans to help doctors exactly locate the part of the brain causing seizures before surgery. It's for people with epilepsy that isn't controlled by medication and who are already planning surgery or an SEEG.
Fuzhou, FujianAges 18–50 - NCT07116421RecruitingEarly Phase 1
Rose smell and seizure-related breathing pauses study
This study tests whether smelling rose oil can reduce or prevent breathing pauses that sometimes happen during seizures. It is for epilepsy patients staying in the hospital for EEG monitoring.
Nashville, TennesseeAges 18 years+ - NCT06967012RecruitingPhase 4
Zonisamide as add-on treatment for children with epilepsy
This trial tests adding zonisamide to the current epilepsy medication for children aged 1 to 14 who still have focal seizures. The goal is to see if the combination works better and is safe.
Nantong, JiangsuAges 1–14 - NCT07095933RecruitingEarly Phase 1
Everolimus for hard-to-control focal epilepsy
This study tests whether the medicine everolimus (taken as a pill) can safely reduce seizures in adults with focal epilepsy that hasn't been controlled by other treatments. You would continue your current seizure medicines and add everolimus.
Beijing, Beijing MunicipalityAges 18–60 - NCT07087821Recruiting
Epilepsy self-management study for depression
This study tests two programs (UPLIFT and PACES) that help people with epilepsy manage depressive symptoms. If you have epilepsy and mild-to-moderate depression, you may be able to join.
Brooklyn, New YorkAges 18 years+ - NCT07075380Recruiting
National survey on physical activity in adults with epilepsy
This survey study asks adults with epilepsy about their physical and sports activity. Your answers will help researchers understand how exercise affects people with epilepsy.
Tain-l'HermitageAges Any age - NCT07064421Recruiting
Brain wave test for kids with hard-to-control seizures
This trial uses a special brain scan (magnetoencephalography) to look at brain activity in children whose seizures don't improve with medication. It may help doctors decide if surgery could be an option.
Guangzhou, GuangdongAges 3–18 - NCT07051629RecruitingPhase 1
Testing a new epilepsy medicine for safety in healthy people and patients
This study tests a new medicine called SIF001 for safety. It first gives the medicine to healthy volunteers, and then to people with epilepsy who have seizures even while on their current medicines. The goal is to find a safe dose.
Tucson, ArizonaAges 18–70 - NCT07026591Recruiting
Epilepsy and driving study
This study looks at driving safety in people with epilepsy. It uses a driving simulator to understand how epilepsy affects driving ability.
Tain-l'HermitageAges 18–65 - NCT07014592Recruiting
Brain activity study in drug-resistant epilepsy patients
This study looks at brain activity in people with epilepsy that does not get better with medicine. Researchers want to record your brain's electrical responses during surgery for your seizures to learn more about how epilepsy works.
Ann Arbor, MichiganAges 22–75 - NCT07013331Recruiting
Brain scan study for Dravet syndrome
This study uses a special PET-MRI scan to look at a brain chemical pathway linked to serotonin (a mood-regulating substance) in people with Dravet syndrome or certain types of epilepsy, and in healthy volunteers. It may help understand how the brain works in these conditions.
Bron, RhoneAges 18–60 - NCT06974305Recruiting
Brain imaging study for epilepsy
This study uses PET, MRI, and EEG scans to learn more about epilepsy. It may help researchers understand how the brain works in people with epilepsy and in healthy volunteers.
Charlestown, MassachusettsAges 18 years+ - NCT06967935Recruiting
Sleep and memory study in epilepsy
This study looks at how sleep and memory work together in people with epilepsy. You will stay in the hospital for at least 4 days with a video EEG to record your brain activity while you sleep and complete memory tasks.
BronAges 18–65
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Common questions
- Are there clinical trials for epilepsy?
- Yes. Clin2 currently lists 328 recruiting epilepsy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a epilepsy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a epilepsy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.