Clinical trials
Epilepsy clinical trials
Below are recruiting epilepsy clinical trials, each written for real people, not researchers. We’re tracking 339 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06504511Recruiting
SCN1A gene study for epilepsy patients in the UK
This study aims to better understand SCN1A-related epilepsies by following patients over time. Researchers hope to learn more about how the condition progresses to help develop future treatments.
GlasgowAges Any age - NCT06537986Recruiting
Thinking and wellbeing program for people with epilepsy
This study tests a program that combines thinking skills training, emotional support, and social guidance for adults with epilepsy. The goal is to see if this program helps improve memory, mood, and daily life.
ChandigarhAges 18–45 - NCT06545214Recruiting
Breathing and arousal in drug-resistant epilepsy
This study looks at breathing problems during seizures in people with drug-resistant focal epilepsy. It aims to understand why some people stop breathing or have low oxygen during seizures, which could help prevent sudden death in epilepsy.
Bron, RhoneAges 18–55 - NCT06550726Recruiting
Advanced MRI for hard-to-control focal epilepsy
This study tests a new, very detailed type of MRI to find the exact spot in the brain where seizures start in people with hard-to-control focal epilepsy. If you have epilepsy that hasn't been helped by medications and previous MRIs didn't find a cause, this scan might give more answers.
Hong KongAges Any age - NCT06557720Recruiting
Imaging study for hard-to-control epilepsy
This study looks at how different brain scans (like MRI, PET, and EEG) can help find the exact spot where seizures start in people whose epilepsy hasn't been controlled by medicines. It aims to better understand drug-resistant epilepsy so doctors can plan more accurate treatments.
Xi'anAges 18–65 - NCT06661759Recruiting
Sleep study for children with epilepsy
This trial tests a sleep improvement program using a clinic and a smartwatch-like device for children ages 1.5 to 9 with epilepsy. It aims to help kids sleep better, which may improve their seizure control and quality of life.
TaipeiAges 1.5 years–9 years - NCT05718817Enrolling by invitationPhase 3
Long-term study of XEN1101 for people with epilepsy
This study gives XEN1101 in an open-label way (everyone knows they’re getting the drug) to people who finished earlier epilepsy studies. It aims to see how the treatment continues to work and whether it’s safe over the long term.
Phoenix, ArizonaAges 12 years+ - NCT06695767Recruiting
Behavioral therapy for epilepsy and depression in veterans
This trial tests a special therapy program for veterans who have both epilepsy and major depression. It uses talk therapy and text message support to help improve mood and seizure control.
Houston, TexasAges 18 years+ - NCT05283811Recruiting
Brain recording during epilepsy care, while doing a memory task
This study listens to brain activity in people with epilepsy who already need electrodes placed inside the brain. Researchers want to understand how different parts of the brain respond while you complete simple thinking and memory-related tasks, which may help improve future treatments.
Los Angeles, CaliforniaAges 10–64 - NCT06708143Recruiting
Temporal interference therapy for drug-resistant epilepsy
This study tests a new, non-invasive treatment called 'temporal interference' for people whose epilepsy seizures are not controlled by medication. It aims to reduce seizures by using low-level electrical fields to calm overactive brain cells.
Beijing, Beijing MunicipalityAges 6–60 - NCT06719791RecruitingEarly Phase 1
Sirolimus for hard-to-treat focal epilepsy
This trial tests if the drug sirolimus can help people with focal seizures (starting in one part of the brain) that don't improve with at least two other medications. It aims to reduce seizure frequency in adults aged 18 to 60.
BeijingAges 18–60 - NCT06780501Recruiting
Database for people with intellectual disabilities and epilepsy
This trial creates a database of health information from people with intellectual disabilities and epilepsy. It aims to help doctors and researchers learn more about these conditions and improve care. The database includes information from medical records, and some people may also be asked to join a research register for future studies.
BodminAges 18 years+ - NCT06782074Recruiting
Epilepsy's impact on thinking and emotions in teens
This study looks at how idiopathic generalized epilepsy affects thinking skills and emotions in adolescents aged 11 to 18. It aims to better understand these effects to improve care.
PaviaAges 11–17 - NCT06792383Recruiting
Psychological and psychiatric assessment before epilepsy surgery
This study evaluates psychological and psychiatric well-being in adults with drug-resistant epilepsy who are being considered for surgery. It aims to understand factors that may affect outcomes and patient experience.
MilanAges 18 years+ - NCT06794606Recruiting
Study for drug-resistant focal epilepsy
This trial looks at ways to diagnose and treat focal epilepsy that isn't controlled by medications. It includes patients with or without a visible brain lesion on imaging.
MilanAges 18 years+ - NCT06863350Recruiting
Closing a heart hole to treat drug-resistant epilepsy
This trial tests if closing a small hole in the heart (called a PFO) can reduce seizures in people whose epilepsy isn't controlled by medication. It might offer a new treatment option for those who have both drug-resistant epilepsy and this heart condition.
Chengdu, SichuanAges 18–60 - NCT06967012RecruitingPhase 4
Zonisamide as add-on treatment for children with epilepsy
This trial tests adding zonisamide to the current epilepsy medication for children aged 1 to 14 who still have focal seizures. The goal is to see if the combination works better and is safe.
Nantong, JiangsuAges 1–14 - NCT06967935Recruiting
Sleep and memory study in epilepsy
This study looks at how sleep and memory work together in people with epilepsy. You will stay in the hospital for at least 4 days with a video EEG to record your brain activity while you sleep and complete memory tasks.
BronAges 18–65 - NCT06974305Recruiting
Brain imaging study for epilepsy
This study uses PET, MRI, and EEG scans to learn more about epilepsy. It may help researchers understand how the brain works in people with epilepsy and in healthy volunteers.
Charlestown, MassachusettsAges 18 years+ - NCT07013331Recruiting
Brain scan study for Dravet syndrome
This study uses a special PET-MRI scan to look at a brain chemical pathway linked to serotonin (a mood-regulating substance) in people with Dravet syndrome or certain types of epilepsy, and in healthy volunteers. It may help understand how the brain works in these conditions.
Bron, RhoneAges 18–60 - NCT07014592Recruiting
Brain activity study in drug-resistant epilepsy patients
This study looks at brain activity in people with epilepsy that does not get better with medicine. Researchers want to record your brain's electrical responses during surgery for your seizures to learn more about how epilepsy works.
Ann Arbor, MichiganAges 22–75 - NCT07026591Recruiting
Epilepsy and driving study
This study looks at driving safety in people with epilepsy. It uses a driving simulator to understand how epilepsy affects driving ability.
Tain-l'HermitageAges 18–65 - NCT07051629RecruitingPhase 1
Testing a new epilepsy medicine for safety in healthy people and patients
This study tests a new medicine called SIF001 for safety. It first gives the medicine to healthy volunteers, and then to people with epilepsy who have seizures even while on their current medicines. The goal is to find a safe dose.
Tucson, ArizonaAges 18–70 - NCT07064421Recruiting
Brain wave test for kids with hard-to-control seizures
This trial uses a special brain scan (magnetoencephalography) to look at brain activity in children whose seizures don't improve with medication. It may help doctors decide if surgery could be an option.
Guangzhou, GuangdongAges 3–18
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Common questions
- Are there clinical trials for epilepsy?
- Yes. Clin2 currently lists 339 recruiting epilepsy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a epilepsy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a epilepsy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.