Clinical trials
Epilepsy clinical trials
Below are recruiting epilepsy clinical trials, each written for real people, not researchers. We’re tracking 328 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06952764Enrolling by invitation
ECLIPSE: Tracking epilepsy cycles to predict seizures
This trial tests if tracking your brain activity with an implanted device can help predict when seizures might happen. It is for adults who have seizures despite medication and already have the RNS System implanted.
San Francisco, CaliforniaAges 18 years+ - NCT05885646Recruiting
Sulthiame study using sleep EEG in children with epilepsy
This trial tests whether sulthiame changes sleep-related brain wave activity (EEG) in children with certain epilepsy syndromes. It may help doctors understand how sulthiame affects the brain’s electrical patterns between seizures.
AngersAges 6–15 - NCT06557720Recruiting
Imaging study for hard-to-control epilepsy
This study looks at how different brain scans (like MRI, PET, and EEG) can help find the exact spot where seizures start in people whose epilepsy hasn't been controlled by medicines. It aims to better understand drug-resistant epilepsy so doctors can plan more accurate treatments.
Xi'anAges 18–65 - NCT06248333Recruiting
Deep brain stimulation for focal motor epilepsy
This trial tests whether deep brain stimulation of a small area in the brain can help reduce seizures that start in the motor part of the brain and do not respond to medication. It may be an option for people who cannot have surgery or whose surgery did not help enough.
Beijing, Beijing MunicipalityAges 14–65 - NCT06794606Recruiting
Study for drug-resistant focal epilepsy
This trial looks at ways to diagnose and treat focal epilepsy that isn't controlled by medications. It includes patients with or without a visible brain lesion on imaging.
MilanAges 18 years+ - NCT06792383Recruiting
Psychological and psychiatric assessment before epilepsy surgery
This study evaluates psychological and psychiatric well-being in adults with drug-resistant epilepsy who are being considered for surgery. It aims to understand factors that may affect outcomes and patient experience.
MilanAges 18 years+ - NCT06716866Enrolling by invitation
Electric field stimulation for epilepsy
This trial tests a new type of brain stimulation using electric fields to treat epilepsy, specifically for people who are already having invasive EEG monitoring as part of their care.
Sacramento, CaliforniaAges 18 years+ - NCT06708143Recruiting
Temporal interference therapy for drug-resistant epilepsy
This study tests a new, non-invasive treatment called 'temporal interference' for people whose epilepsy seizures are not controlled by medication. It aims to reduce seizures by using low-level electrical fields to calm overactive brain cells.
Beijing, Beijing MunicipalityAges 6–60 - NCT06401538RecruitingPhase 2
BMB-101 for absence epilepsy and DEE
This trial tests a new drug called BMB-101 for people with absence epilepsy (including Jeavons syndrome) or developmental epileptic encephalopathies (DEE) like Dravet or Lennox-Gastaut. It aims to see if the drug can reduce seizure frequency and is safe.
Randwick, New South WalesAges 18–65 - NCT06661759Recruiting
Sleep study for children with epilepsy
This trial tests a sleep improvement program using a clinic and a smartwatch-like device for children ages 1.5 to 9 with epilepsy. It aims to help kids sleep better, which may improve their seizure control and quality of life.
TaipeiAges 1.5 years–9 years - NCT06612775RecruitingPhase 2
Testing CB03-154 for adults with focal epilepsy
This trial tests a new medication, CB03-154, to see if it is safe and can reduce seizures in adults with focal epilepsy. You may be able to join if you have had focal epilepsy for at least 2 years and are on a stable dose of 1 to 3 anti-seizure medications.
Melbourne, VictoriaAges 18–70 - NCT06550726Recruiting
Advanced MRI for hard-to-control focal epilepsy
This study tests a new, very detailed type of MRI to find the exact spot in the brain where seizures start in people with hard-to-control focal epilepsy. If you have epilepsy that hasn't been helped by medications and previous MRIs didn't find a cause, this scan might give more answers.
Hong KongAges Any age - NCT06545214Recruiting
Breathing and arousal in drug-resistant epilepsy
This study looks at breathing problems during seizures in people with drug-resistant focal epilepsy. It aims to understand why some people stop breathing or have low oxygen during seizures, which could help prevent sudden death in epilepsy.
Bron, RhoneAges 18–55 - NCT06521437Enrolling by invitation
How the brain's memory center works in epilepsy
This study looks at how the hippocampus (a part of the brain important for memory) works in people with epilepsy. If you have a hard-to-treat type of epilepsy called MTLE, this research may help doctors understand memory and brain function better.
Chicago, IllinoisAges 18 years+ - NCT03400371Recruiting
Study of brain signals in juvenile myoclonic epilepsy
This study looks at EEG brain recordings in people with juvenile myoclonic epilepsy, especially those whose seizures started between ages 10 and 25. It may help researchers better understand how this epilepsy works and improve future care.
New York, New YorkAges 10–40 - NCT02824822Recruiting
Genetic test study for heart rhythm risk in people with seizures
This study checks whether genetic markers are linked to heart rhythm problems in people with epilepsy or seizure-related events, and in some close relatives. It may help doctors better spot who is at risk for dangerous heart rhythm issues.
Rochester, MinnesotaAges 18–50 - NCT06483061RecruitingPhase 2
Enhanced MRI Study for Epilepsy and Healthy Volunteers
This study tests whether a special MRI contrast agent (Ferumoxytol) can improve brain imaging in healthy people and people with temporal lobe epilepsy. It may help doctors see more detail in the brain.
Edmonton, AlbertaAges 18–64 - NCT06304389Recruiting
Blue light therapy for epilepsy with vagus nerve stimulation
This trial tests if blue light exposure can improve the effects of vagus nerve stimulation (VNS) in people with epilepsy that is hard to control. It also includes some healthy volunteers for comparison. The goal is to find new ways to make VNS work better.
Woluwe-Saint-LambertAges 18–60 - NCT06466681Recruiting
Attention changes after a seizure in epilepsy
This study looks at how attention and concentration change right after a seizure in people with epilepsy. It uses a short hospital stay to track these changes, which may help improve understanding and future treatment.
LilleAges 18–80 - NCT06422923RecruitingPhase 1/Phase 2
Cell therapy for hard-to-treat epilepsy starting in both temporal lobes
This trial tests a new cell therapy (NRTX-1001) for people with epilepsy that starts in both sides of the brain's temporal lobes and doesn't get better with medication. It aims to reduce or stop seizures.
Little Rock, ArkansasAges 18–75 - NCT06271785Recruiting
Predicting success of epilepsy surgery in children
This study uses a special, detailed brain-mapping technique (called high-resolution electrical source imaging) to see how well it can predict success after epilepsy surgery in children. It aims to help doctors decide which children might benefit most from surgery.
AngersAges 2–17 - NCT06376279Enrolling by invitation
Genetic testing for metabolic diseases
This trial uses genetic testing to find the cause of suspected metabolic diseases, including some cases of epilepsy. It may help you get a clearer diagnosis and guide treatment.
Ages Any age - NCT06369571Enrolling by invitationPhase 1/Phase 2
Improving heart health in adults with epilepsy on a modified Atkins diet
This study tests whether a statin medication (atorvastatin) can help lower cholesterol and improve heart health in adults with epilepsy who have been on a modified Atkins diet for a year or more. It may be a good fit if you have high cholesterol and are not already on a statin or have had heart problems.
Baltimore, MarylandAges 18 years+ - NCT04253379Recruiting
Study of social understanding in children with epilepsy
This study looks at how children with epilepsy understand social cues, compared with other children the same age. You may be asked to complete simple thinking and social tasks to see what differences exist and what they might mean.
ReimsAges 6–12
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Common questions
- Are there clinical trials for epilepsy?
- Yes. Clin2 currently lists 328 recruiting epilepsy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a epilepsy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a epilepsy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.