Clinical trials
Functionality clinical trials
Below are recruiting functionality clinical trials, each written for real people, not researchers. We’re tracking 2,577 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04812314Recruiting
Study how exercise changes body fat and metabolism
This study looks at how starting exercise changes the structure and function of body fat. It may help you understand how exercise affects things like cholesterol and blood sugar, even if you’re not currently exercising regularly.
Ann Arbor, MichiganAges 18–40 - NCT04814082Recruiting
Compare two knee implant types for walking and function
This study compares two designs of knee replacement implants to see how they affect walking, function, and outcomes after surgery. You may be randomly assigned to one of the implant types used for your specific, approved knee replacement.
Baltimore, MarylandAges 18–75 - NCT04831957Recruiting
Testing thyroid hormone changes after TAVI in older adults
This study looks at how thyroid problems may develop after a heart procedure called TAVI in people age 70 and older. It may help doctors spot thyroid side effects earlier so they can treat them sooner.
BrusselsAges 70 years+ - NCT04833426RecruitingPhase 3
Testosterone levels around prostate surgery and recovery outcomes
This trial studies whether testosterone levels before and around radical prostate surgery affect cancer control and sexual/physical recovery. It may help doctors understand who benefits from testosterone replacement and who should not.
AmsterdamAges 18 years+ - NCT04858347Recruiting
Study of a specific knee implant and recovery outcomes
This trial looks at how well a particular knee replacement (a GEMINI SL fixed-bearing prosthesis) works and how people function after surgery. It may help doctors learn what to expect for recovery and long-term results with this implant.
Cali, Valle del Cauca DepartmentAges 18–80 - NCT04859335Recruiting
Tracking balance and inner-ear function after Gamma Knife for schwannoma
This study looks at how balance and inner-ear (vestibular) function change after Gamma Knife radiosurgery for vestibular schwannoma. It may help doctors understand what to expect during recovery and how well these functions improve.
ToulouseAges 18–65 - NCT04861194Recruiting
Test treatment plans to preserve erections during prostate radiation
This trial studies ways to help preserve erectile function while you receive radiation treatment for prostate cancer. It may help by aiming to protect erections, especially for people at low to intermediate risk.
Utrecht, UtrechtAges 18 years+ - NCT04879862Recruiting
Study of walking and bladder recovery after recent spinal injury
This study looks at how leg movement and bladder function change after an acute spinal cord injury. It’s meant for adults who recently injured their spine and cannot stand or move their leg joints on their own.
West Orange, New JerseyAges 18–65 - NCT04883463Recruiting
Brain and spinal stimulation to improve breathing after SCI
This trial tests a neuromodulation treatment to improve breathing in people living with a cervical spinal cord injury who have significant breathing problems. If you qualify, you would have regular weekly testing over many months to see whether breathing and breathing support needs improve.
Los Angeles, CaliforniaAges 18–75 - NCT04883502Recruiting
Testing a technique to rebuild bone lost after injury
This study looks at a surgical method that creates an “induced membrane” to help rebuild bone after traumatic injury. It may help people whose limb bones were damaged and are missing part of the bone.
ClamartAges 18 years+ - NCT04898790Recruiting
Testing ways to improve thinking after bone marrow transplant
This study looks at whether a physical activity program and related study measures can improve thinking and memory in older adults around the time of a stem cell transplant. If you qualify and participate, the team will compare outcomes between groups to see what approach works best.
Omaha, NebraskaAges 19 years+ - NCT04917471Recruiting
Testing nitrate to improve red blood cell function in type 2 diabetes
This study looks at whether taking nitrate can improve how red blood cells work in people with type 2 diabetes. You may be asked to follow a specific plan and avoid certain foods or medicines that could affect the results.
StockholmAges 18 years+ - NCT04919980Recruiting
Testing a new mitral valve repair device for high-surgery-risk patients
This study looks at a new way to treat a leaky mitral heart valve using the INNOVALVE system. It’s meant for people who have symptoms from mitral regurgitation but are considered high risk for open-heart surgery, to see if the approach can help safely.
Los Angeles, CaliforniaAges 18 years+ - NCT04920318Recruiting
Study to improve language in primary progressive aphasia
This trial looks at ways to improve language abilities in people with primary progressive aphasia (a long-term brain condition that affects speech and language). It may help if your communication problems come from this condition and you can safely take part in the study activities, which likely involve language practice and MRI scanning.
Tucson, ArizonaAges 45–80 - NCT04926597Recruiting
Extra nutrition after hospital discharge for higher-risk patients
This study looks at whether continuing nutritional support after you leave the hospital can reduce death risk and help you recover better—like improving strength, frailty, and daily functioning. It targets people who are at higher risk of poor nutrition during/after their hospital stay.
BarcelonaAges 18 years+ - NCT07224490RecruitingPhase 1
Kisspeptin test for brain function after COVID-19
This study tests how the brain's reproductive hormone system works after a COVID-19 infection using a substance called kisspeptin. It may help explain symptoms like changes in periods or hormone levels in people with long COVID.
Boston, MassachusettsAges 18–60 - NCT07698405Recruiting
Advanced rehab technology for arm recovery after stroke
This study tests whether advanced technology-based rehabilitation can help people who have had a stroke regain movement and use of their affected arm. It may be a good option if you have had a single stroke and still have some arm weakness but no severe muscle tightness or memory problems.
Fiorenzuola d'Arda, PiacenzaAges 18 years+ - NCT07694804Recruiting
Physical therapy for arm and hand function in children with cerebral palsy
This study tests two types of physical therapy to help children with spastic diplegic cerebral palsy improve the use of their arms and hands. The treatments focus on stretching and coordination exercises, and they may help your child with daily activities.
Mansehra, KPKAges 6–12 - NCT07699380RecruitingPhase 2
Metabolic study to improve insulin sensitivity in type 1 diabetes
This study tests a new medication to see if it can improve how your body responds to insulin and boost your cells' energy (mitochondrial function). It is for adults with type 1 diabetes who are already on insulin and have good overall health.
Seattle, WashingtonAges 18–69 - NCT07051655Recruiting
Ketone drink for thinking and memory
This study tests whether a drink containing ketones (a natural energy source for the brain) can improve thinking and memory. It involves three groups: people with obesity, lean people, and athletes.
Birmingham, AlabamaAges 19–55 - NCT07695545Recruiting
Lipid metabolism study in ascending aortic aneurysm
This study looks at how fat metabolism and cell energy centers (mitochondria) work in patients having surgery for an ascending aortic aneurysm. It aims to understand differences between people with bicuspid or tricuspid aortic valves.
DijonAges 18 years+ - NCT04938362Recruiting
Study brain recovery after abscess using memory and brain scans
This study looks at how thinking and energy levels change after a brain abscess. It may help researchers understand what affects recovery and fatigue, using thinking tests and brain imaging/brain-wave checks.
OsloAges 16 years+ - NCT04939935RecruitingPhase 3
Metformin to slow kidney decline in adults with polycystic kidneys
This Phase 3 study tests whether taking metformin can slow the decline of kidney function in adults with autosomal dominant polycystic kidney disease (ADPKD). You may be eligible if you have ADPKD and signs that your kidneys are starting to decline faster than expected.
Gosford, New South WalesAges 18–70 - NCT04969042RecruitingPhase 1
Closed-loop spinal cord stimulation for spinal cord injury rehab
This Phase 1 study tests a computer-controlled spinal cord stimulation system to help people with spinal cord injuries during rehabilitation. It is mainly looking at safety and whether the device can be used during follow-up visits and training.
Beijing, Beijing MunicipalityAges 18–70
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Common questions
- Are there clinical trials for functionality?
- Yes. Clin2 currently lists 2,577 recruiting functionality studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a functionality trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a functionality trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.