Clinical trials
Functionality clinical trials
Below are recruiting functionality clinical trials, each written for real people, not researchers. We’re tracking 2,565 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT01535430Recruiting
Mapping brain function in people with certain brain tumors
This study uses brain “mapping” tests (with MRI and possibly other methods) to identify important brain functions near a tumor. It may help your care team plan a safer surgery by understanding which brain areas do critical tasks.
Omaha, NebraskaAges 19 years+ - NCT02098265Recruiting
Brain-signal device for stroke arm rehabilitation
This study tests a device that uses brain activity signals to trigger stroke arm therapy. It may help improve how well your upper arm and hand function by timing the training to your brain’s patterns.
Madison, WisconsinAges 18 years+ - NCT02362685Recruiting
Metabolic exercise testing study
This study is about doing a breathing-and-heart performance test while you exercise to better understand how your body uses energy. You may join if you’re referred for this type of test and can safely complete it.
BrestAges 5 years+ - NCT02290834Recruiting
Studying brain and thinking changes after chemotherapy in older breast cancer patients
This study looks at how chemotherapy may affect memory and thinking, using thinking tests and possibly brain imaging. It compares older breast cancer patients who do and do not get chemotherapy, plus a group of healthy older adults.
Boston, MassachusettsAges 60 years+ - NCT02543424Recruiting
Testing movement and thinking in brain-injury and cerebral palsy
This study looks at how people’s arm/hand movement and attention-thinking skills work after brain injury or cerebral palsy. You might be invited to tasks and simple instructions to help researchers understand function and possible support strategies.
Ottignies, Brabant WallonAges 5 years+ - NCT02108054Recruiting
Building and testing tasks to measure brain and movement
This study helps create and test simple tasks that measure brain function and movement in people with different backgrounds. It may help researchers better understand how the brain and body work, which can improve future alcohol-related treatments.
Bethesda, MarylandAges 18–65 - NCT02798705Recruiting
Testing heart tiny blood vessel function in amyloidosis
This study measures how well the heart’s tiny blood vessels work in people with cardiac amyloidosis, using special heart testing. It may help doctors understand the disease better and improve how patients are evaluated over time.
SeoulAges 18–85 - NCT02833285Recruiting
Study immune cells in people with gum disease
This study looks at how the immune system (B cells) works in gum disease and may help doctors better understand the condition. You may be asked to take part if you need gum surgery and meet other health and treatment rules.
BrestAges 18–75 - NCT02299921Recruiting
Alcohol and drug effects on immunity in ICU breathing patients
This study looks at how alcohol and other drugs can affect the body’s immune system in people who are very sick in the ICU due to breathing problems. It may help doctors better understand immune changes during critical illness and respiratory failure.
Aurora, ColoradoAges 18–90 - NCT02617966Recruiting
Test of how rod and cone vision work in eye disease
This study measures how your eyes use two types of light-sensing cells (rods for dim light and cones for clearer detail). It may help researchers better understand retinal (retina) diseases and how well vision is functioning.
Bethesda, MarylandAges 5–100 - NCT02846272Recruiting
Brain scans in children with hard-to-treat epilepsy
This study uses special brain imaging to look at how brain cells and networks work in children with intractable, or hard-to-treat, epilepsy. The goal is to connect the scan findings with what’s found in clinical evaluation to better understand the condition.
Houston, TexasAges birth–18 years - NCT02504788Recruiting
Protect the brain’s memory area during whole-brain radiation
This study tests whether avoiding the hippocampus (a part of the brain important for memory) during whole-brain radiotherapy can slow down thinking and memory decline. It may help some people preserve neurocognitive function while still treating brain metastases.
TaoyuanAges 18–84 - NCT02663362Recruiting
Whole-body MRI and scan method testing
This study tests and checks a new way of using MRI scans (and special scan add-ons) across the whole body. You may be able to help researchers improve the imaging tools and methods for future medical use.
Orlando, FloridaAges 12–89 - NCT02896348Recruiting
Home therapy training for hand function after stroke
This trial tests a physio-and-neuro “platform” to help retrain hand movement at home in people who are at least 6 months out from a stroke. It may help improve hand function and confidence doing daily tasks using an at-home retraining program.
Boston, MassachusettsAges 21–80 - NCT02754544Recruiting
Brain mapping during tumor surgery while you are awake
This study uses special recording sensors during brain tumor surgery to map the brain areas that control movement and speech. It may help the surgical team protect these key functions while removing the tumor.
Houston, TexasAges 18 years+ - NCT02331979Recruiting
Neuromodulation trial to improve bladder function after spinal injury
This trial tests a nerve-stimulation approach to improve bladder control in people with spinal cord injury. It specifically targets bladder problems that require clean intermittent catheter use and includes regular testing over 6 months.
Los Angeles, CaliforniaAges 18–45 - NCT02629107Recruiting
Sleep and brain scan study with sound cues
This study checks how your brain responds while you sleep using an MRI scanner and gentle sound signals. It may help researchers better understand sleep and brain function.
Bethesda, MarylandAges 18–34 - NCT03094312Recruiting
Check how a seizure-brain procedure affects thinking after surgery
This study looks at whether a special brain-recording procedure for difficult-to-control seizures changes a person’s memory, thinking, or other brain skills afterward. It may help doctors understand risks and plan care for people undergoing the procedure.
BronAges 18–65 - NCT03097185Recruiting
Checking how well transplanted islet cells work in chronic pancreatitis
This study looks at how well a treatment works after islet cell transplantation done for people with long-term (chronic) pancreatitis. It may help doctors better understand graft (transplant) function and how to choose the best approach and follow-up.
Dallas, TexasAges 18 years+ - NCT03160131Recruiting
Rehab program to improve vision after brain injury
This study looks at rehabilitation to improve vision after a brain injury. It may help people with significant vision problems regain everyday visual function.
Copenhagen, HellerupAges 14 years+ - NCT03142152Recruiting
Mitral valve implant for heart failure with leaky mitral valve
This trial tests whether a device called the Carillon Mitral Contour System can help people with heart failure caused by a mild-to-moderate leaky mitral valve. You’d be compared against a control group, and the goal is to improve heart failure symptoms and outcomes.
Gilbert, ArizonaAges 18 years+ - NCT03240328RecruitingPhase 1
CAR-T therapy study for rebuilding HIV immune defenses
This early-stage study tests whether CAR-T cells can help rebuild the immune system’s ability to fight HIV. You may be a candidate if your HIV is well controlled on standard treatment and you don’t have certain serious infections or organ problems.
Guangzhou, GuangdongAges 18–60 - NCT07677033Recruiting
Bone and muscle health study for adults
This study looks at how well your bones and muscles work together. By measuring your bone density and handgrip strength, doctors can better understand your bone health and find ways to keep you strong as you age.
Küçükçekmece, IstanbulAges 18 years+ - NCT07124520Recruiting
Lingual strength training after tongue cancer surgery
This study tests if using a device to exercise your tongue after partial tongue removal helps you recover tongue strength and function better than standard care. It is for people having their first surgery for oral tongue cancer.
Basking Ridge, New JerseyAges 18 years+
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Common questions
- Are there clinical trials for functionality?
- Yes. Clin2 currently lists 2,565 recruiting functionality studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a functionality trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a functionality trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.