Clinical trials
General Population (no Specific Condition or Disease) clinical trials
Below are recruiting general population (no specific condition or disease) clinical trials, each written for real people, not researchers. We’re tracking 10,548 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04432623Enrolling by invitationPhase 1/Phase 2
Test drug for adults with beta thalassemia intermedia
This trial studies an investigational medicine in adults with beta thalassemia intermedia (including non-transfusion dependent thalassemia). The goal is to see how well the treatment works and how safe it is for people whose hemoglobin runs in a certain range.
Oakland, CaliforniaAges 18 years+ - NCT04433455Recruiting
Brain and thinking health in hemodialysis patients
This study looks at how blood vessel problems in the brain and thinking (cognition) are related in people who are on long-term hemodialysis for kidney failure. By joining, you help doctors learn how to better protect brain health in dialysis patients.
Shanghai, Shanghai MunicipalityAges 50–85 - NCT04392206RecruitingPhase 1
Study paste to prevent narrowing in new arm dialysis fistulas
This Phase 1 study tests a treatment (called AMSCs) to help stop scar-like narrowing at the connection point of a new arm dialysis fistula. If it works and is safe, it could improve long-term fistula function so dialysis can work better.
Jacksonville, FloridaAges 18–85 - NCT04401605Recruiting
Fermented foods diet for ulcerative colitis symptoms
This study tests whether adding fermented foods to your diet can improve symptoms of ulcerative colitis. It also looks at people with intestinal inflammation markers to see if diet changes may help them feel better.
Palo Alto, CaliforniaAges 18 years+ - NCT04388943Recruiting
BRICCS study: health data for cardiovascular research
This trial helps researchers study heart (cardiovascular) conditions using information collected about your care. It may help improve how doctors understand and treat cardiovascular diseases over time.
LeicesterAges 18–90 - NCT04414046RecruitingPhase 2
Stem cell transplant using T-cell cleanup for immune and metabolism disorders
This Phase 2 study tests a specialized stem cell transplant that removes certain “T-cells” (a type of immune cell) to treat children with serious immune system or inherited metabolic problems. The goal is to improve or stabilize disease by resetting the immune system and supporting the body’s function.
St. Petersburg, FloridaAges Up to 21 years - NCT04442646Recruiting
Asthma education program for better self-management
This study looks at an “Asthma School,” an education and support program, to help adults manage their asthma day to day. It may help you learn practical ways to control symptoms and know what to do when asthma flares.
Tradate, LombardyAges 18–85 - NCT04461821Recruiting
Breath test to study disease in children
This study uses a special machine to analyze exhaled breath to learn about different illnesses in children and teens. It may help researchers find breathing “signals” that reflect conditions like breathing problems, nervous system issues, or new/worsening type 1 diabetes.
BaselAges Up to 22 years - NCT04466059Recruiting
AI tool for leukemia diagnosis using blood or marrow samples
This study tests whether an AI (computer system) can help improve leukemia and related blood cancer diagnoses. You may be able to help if your doctor is already evaluating you for a possible blood disorder and your sample is high enough quality for testing.
Munich, BavariaAges 18 years+ - NCT04422912RecruitingPhase 1/Phase 2
Cell therapy trial for active pemphigus vulgaris
This Phase 1/2 trial tests the safety and dosing of genetically modified immune cells made from your own blood (autologous CAR T or related cells) for active pemphigus vulgaris. It may help control disease that is not adequately managed with standard medicines.
Redwood City, CaliforniaAges 18 years+ - NCT04418830Enrolling by invitation
Study of a spine cage implant for degenerative back problems
This trial studies how well specific lumbar (lower back) implant “cages” help fuse vertebrae in people with degenerative disc disease, spinal slippage, narrowing, curvature, or forward-bending deformity. It may help by testing an approach to improve stability and reduce symptoms after surgery.
La Jolla, CaliforniaAges 18 years+ - NCT04373317RecruitingPhase 4
Comparing two medicines for hallucinations in Parkinson's disease
This study compares two drugs, pimavanserin and quetiapine, to see which works better for hallucinations or delusions caused by Parkinson's disease. The goal is to help patients manage these symptoms more effectively.
Tucson, ArizonaAges 40 years+ - NCT04339777RecruitingPhase 2
Bone marrow transplant for inherited immune system disorders
This trial studies how well a donor bone marrow (stem cell) transplant works for people with inherited immune system problems (called immune deficiencies). It’s for patients who haven’t improved with usual treatment or don’t have another good option.
Bethesda, MarylandAges 4–69 - NCT04289571RecruitingPhase 1
Virtual reality vision testing for people with retinal disease
This early-stage study uses virtual reality tasks to check how well a person can move and function using their eyesight. It may help researchers measure vision abilities in a way that could guide future care for retinal disease.
Bethesda, MarylandAges 5–120 - NCT04364503Enrolling by invitation
Study that analyzes de-identified patient samples and records
This trial checks how well patient samples and health records can be analyzed when names are removed (“de-identified”) and privacy rules are followed. You might be included if you agree in writing and your sample data can be used for this research and/or your doctor requests it.
Los Angeles, CaliforniaAges Any age - NCT04312633Recruiting
Testing a new throat biopsy mapping method for Barrett’s disease
This study follows people for 5 years to see how well a new biopsy-mapping test (WATS3D) works during routine upper endoscopy. It may help doctors find Barrett’s esophagus changes earlier and better guide follow-up after treatment.
Bethpage, New YorkAges 18 years+ - NCT04279496Enrolling by invitation
CT heart scan registry to track outcomes over time
This is a research registry that follows people who are already getting a CT scan of their heart arteries for medical reasons. It aims to better understand how these scans relate to future heart outcomes, while collecting follow-up health information.
Charlottesville, VirginiaAges 18 years+ - NCT04364295Enrolling by invitation
Patients who used SeaSpine products join a global registry
This registry collects information from people who have been treated with at least one SeaSpine product and had standard imaging and symptom surveys before and after surgery. It helps doctors understand outcomes over time and can support future improvements in care.
Durango, ColoradoAges Any age - NCT04333706RecruitingPhase 1/Phase 2
Sarilumab plus capecitabine for certain breast cancers
This trial studies whether adding sarilumab to capecitabine can shrink or control metastatic or high-risk breast cancer that lacks HER2 and is either triple-negative or hormone-resistant. It aims to find a safe dose first, then look at how well the treatment works compared with historical results.
Los Angeles, CaliforniaAges 18–99 - NCT04281823Recruiting
MRI heart scan study for people with heart conditions
This study looks at heart problems using a special MRI scan called a cardiovascular magnetic resonance (CMR) scan. It may help doctors learn more about how to assess and understand cardiovascular disease using detailed heart images.
Houston, TexasAges Any age - NCT04258488RecruitingPhase 4
Blood thinner pill vs warfarin after mechanical aortic valve
This study compares a blood thinner pill (a factor Xa inhibitor) with warfarin (vitamin K antagonist) in people who have had a mechanical aortic valve replacement. It looks at which option works better and is safer over the long term.
Bucheon-siAges 19 years+ - NCT04254861Recruiting
Platelet treatment for deep gum bone defects
This trial studies an “autologous platelet concentrate” (a gel made from your own blood) to help heal deep bone defects caused by periodontitis. It’s meant for adults with specific measurements in one or more gum pockets and bone areas after recent non-surgical gum treatment.
LondonAges 25–80 - NCT04374799RecruitingPhase 3
Heparin vs placebo during cardiac catheterization
This trial tests whether giving heparin (a blood thinner) during a specific type of heart procedure is safer and works better than not giving it. It focuses on patients where the blood supply in the hand’s artery connection is functioning properly.
Hamilton, OntarioAges 18 years+ - NCT04372875Recruiting
Help for teens using health tech in the emergency room
This trial tests whether using a health information technology tool in the emergency department can improve sexual health care and reduce health disparities for teens. It focuses on gathering survey and screening information so care can better meet needs.
Washington D.C., District of ColumbiaAges 15–21
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Common questions
- Are there clinical trials for general population (no specific condition or disease)?
- Yes. Clin2 currently lists 10,548 recruiting general population (no specific condition or disease) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a general population (no specific condition or disease) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a general population (no specific condition or disease) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.