Clinical trials
Genetic Syndrome clinical trials
Below are recruiting genetic syndrome clinical trials, each written for real people, not researchers. We’re tracking 90 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06952413RecruitingPhase 2
Rituximab for chronic fatigue syndrome (ME/CFS) trial
This trial tests if rituximab, a drug that affects the immune system, can help people with ME/CFS. You'll receive the drug in the hospital and be monitored for safety and improvement.
Kodaira, TokyoAges 18–65 - NCT04494945Recruiting
Help for people with inherited cancer risk genes
This study helps identify people who may have an inherited cancer risk and checks how best to support them. Depending on the group, you may only fill out surveys, or you may also create an app account and possibly provide a DNA sample.
Portland, OregonAges 18 years+ - NCT07674290RecruitingPhase 4
Study of MC4R Agonist for Bardet-Biedl Syndrome and Genetic Obesity
This trial tests a drug called setmelanotide for people with Bardet-Biedl Syndrome (a rare genetic condition) or other severe genetic obesity. It looks at how well the drug works in real-world settings, not just in a lab.
EssenAges Any age - NCT06450171Recruiting
Multi-cancer early detection test for people at high risk
This study tests a blood-based multi-cancer early detection (MCED) screening test in people with a high risk of cancer due to inherited gene changes or strong family history. The goal is to see if this test can find cancer early.
Boston, MassachusettsAges 22 years+ - NCT01441089Recruiting
Donate blood for genetic testing in an NIH research study
This study collects blood from people already in an NIH (National Institutes of Health) clinical research program to run genetic tests. It may help researchers understand cancer and related inherited conditions by studying DNA changes.
Bethesda, MarylandAges 3 years+ - NCT03087253Recruiting
Study of what causes and affects lipodystrophy
This study observes people with lipodystrophy to better understand how the condition develops and affects the body over time. It may help researchers learn who is most affected and guide future treatments.
Bethesda, MarylandAges Any age - NCT05767203Recruiting
Study genetic and blood markers in people with inherited intellectual disability
This study looks at genetic-related and blood/biologic markers in people with an inherited (genetic) intellectual disability. The goal is to better understand these differences and how they might relate to the condition.
ParisAges Any age - NCT06226194Recruiting
Genes and weight loss after bariatric surgery
This study looks at how your genes might affect how much weight you lose after gastric sleeve or gastric bypass surgery. You may be able to help doctors better predict weight loss results for future patients.
Lleida, LeidaAges 18–65 - NCT05133245Enrolling by invitation
Study of genes in people with PHACE syndrome
This study looks at genetic (DNA) differences in people who have PHACE syndrome. It also includes an eye exam, and results may help doctors better understand the condition.
Nashville, TennesseeAges Any age - NCT04731857Recruiting
Genetic testing results study for rare diseases
This study looks at how well different genetic tests (whole exome/genome sequencing and standard genetic tests) work for diagnosing rare genetic diseases and inherited cancer conditions. It may help confirm which testing approach provides the clearest results for families.
TübingenAges Any age - NCT04903782Recruiting
Family whole-genome testing for children with newly diagnosed cancer
This study offers whole-genome testing (a way to read a person’s DNA) to families after a child is newly diagnosed with cancer. It aims to find inherited changes that may explain why cancer happened and guide future care or monitoring.
Newcastle, New South WalesAges Up to 21 years - NCT04738708Recruiting
Phone vs in-person genetic counseling for cancer risk
This study compares two ways of getting genetic counseling—by phone/video or in person—for people who may have hereditary cancer syndromes like HBOC or Lynch syndrome. It may help find which counseling approach works best for understanding results and next steps.
SingaporeAges 21 years+ - NCT06647927Recruiting
Genetic study for better Brugada diagnosis
This study looks at the genes of people with Brugada Syndrome to find new markers that can help doctors diagnose it more accurately. If you have Brugada Syndrome, joining could help improve understanding and care for this condition.
San Donato Milanese, MilanAges 18 years+ - NCT05126810Recruiting
Standard versus personalized counseling for TP53 test results
This trial compares standard genetic counseling with a more personalized approach for people considering or receiving TP53 genetic testing. It may help by seeing which counseling style better supports you before and after testing for a TP53 inherited change.
Houston, TexasAges Any age - NCT03423758Recruiting
Genetic study of eye diseases: PXF, angle-closure and open glaucoma
This study looks at blood or DNA-related factors that may explain why certain glaucoma and related eye conditions happen. It may help researchers understand risk and causes across different glaucoma types.
ViennaAges 21–105 - NCT05348564Recruiting
Family genetic screening methods for heart rhythm risk
This study compares two ways to find relatives who may carry a specific inherited genetic change. It may help your family learn faster who should get follow-up testing and care.
Lancaster, PennsylvaniaAges 18 years+ - NCT06334666Enrolling by invitation
Step counting for fatty liver disease management
This trial tests if using a pedometer to track daily steps can help people with a type of fatty liver disease (called MASLD) become more active and improve their health. It may be a good fit if you are not already very active and want to try a simple way to manage your condition.
Bangkoknoi, BangkokAges 18 years+ - NCT07378423Recruiting
Survey on signs of cancer at birth
This trial asks newly diagnosed children and young adults with certain types of cancer to fill out a questionnaire about signs of cancer present at birth. The answers may help improve early detection of childhood cancer.
BernAges Up to 21 years - NCT05937594Recruiting
Testing microRNA markers to spot newborn opioid withdrawal
This study looks at tiny genetic signals (microRNA) in newborn samples to identify neonatal opioid withdrawal syndrome. It may help doctors recognize withdrawal sooner, so babies can get the right care faster.
Hershey, PennsylvaniaAges 1 day–5 days - NCT05578105Recruiting
Study of autoimmune polyglandular disease genetics in Taiwan
This study looks at how common autoimmune polyglandular syndrome type II is in Taiwan and what genetic differences may be involved. It uses past hospital visit records and focuses on people who had a specific pattern of autoimmune conditions.
TaipeiAges 20 years+ - NCT06353607Recruiting
Genetics of aortic aneurysm and dissection
This study looks at the genetic reasons behind aortic aneurysms and sudden aortic tears. By studying people who had surgery at the University Hospital Basel, researchers hope to find inherited patterns that could help predict and prevent these serious conditions.
BaselAges 18 years+ - NCT00341874Enrolling by invitation
Genetic study of deafness in Pakistani families
This study looks at genetic causes of deafness by comparing affected and unaffected family members. It may help researchers understand why some people are born or develop deafness and guide future diagnosis for families in Pakistan.
LahoreAges 2 years+ - NCT01443468Recruiting
Study of Li-Fraumeni syndrome family cancer risk
This study collects medical and genetic information to better understand how often cancer develops in people with Li-Fraumeni syndrome and related family risks. It may help families and doctors plan earlier awareness and follow-up over a person’s lifetime.
Bethesda, MarylandAges Any age - NCT00482794Recruiting
Study genetic risk factors for antiphospholipid antibody syndrome
This study looks at genetic (inherited) risk factors in people who have antiphospholipid antibodies and related symptoms. Your results may help researchers better predict who is at risk and improve care for antiphospholipid antibody syndrome.
Durham, North CarolinaAges Any age
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Common questions
- Are there clinical trials for genetic syndrome?
- Yes. Clin2 currently lists 90 recruiting genetic syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a genetic syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a genetic syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.