Clinical trials
Heart Diseases clinical trials
Below are recruiting heart diseases clinical trials, each written for real people, not researchers. We’re tracking 749 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06518681Enrolling by invitation
Testing a new polymer heart valve for aortic disease
This trial tests a new type of artificial heart valve made of polymer (a special plastic-like material) for people with severe aortic valve disease. It aims to see if the valve is safe and works well, giving you an option for a replacement valve that might last longer.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05661305Recruiting
Egyptian healthy adults for heart and MRI study
This trial studies how healthy hearts work in Egyptian adults who do not have known heart problems. It may help researchers understand heart health and risk factors, using an MRI scan.
AswānAges 18 years+ - NCT06954727Recruiting
Study on first-time right heart catheterization for lung blood pressure
This study is watching people who are having their first right heart catheterization to better understand and manage lung blood pressure problems. It may help doctors improve diagnosis and treatment for people with shortness of breath or suspected pulmonary hypertension.
BeijingAges 14 years+ - NCT07391683Recruiting
Heart failure support before heart surgery
This trial tests if special remote care before heart surgery can improve recovery for people with heart failure. You will have regular check-ins by video or phone to help manage your health before your operation.
Innsbruck, TyrolAges 18 years+ - NCT07760363Recruiting
Foot exercise device for leg swelling
This study tests if using a foot pedal device while lying down can help reduce leg swelling in the hospital. It aims to see if this simple exercise can improve comfort and outcomes for people with fluid buildup.
Tulsa, OklahomaAges 18 years+ - NCT03524222Recruiting
Home hospital care for adults after sudden illness
This trial tests whether certain adults can safely receive hospital-level care at home instead of staying in the hospital, using a home care team. It may help you recover in your own home if your condition fits their plan and you have support at home.
Boston, MassachusettsAges 18 years+ - NCT05100992Recruiting
Bifurcation heart procedure registry for adults
This study is a real-world registry that follows adults who are getting a specific type of heart stent procedure in a forked artery. It helps doctors learn what happens before and after the procedure and improve care.
Minneapolis, MinnesotaAges 18 years+ - NCT05532631Recruiting
Compare stent procedure versus bypass surgery for weak heart
This study compares two ways to improve blood flow to the heart—using stents through a catheter or bypass surgery—in people with heart muscle weakness and blockages in more than one coronary artery. It may help identify which approach leads to better outcomes over at least two years.
Créteil, Val De MarneAges 18 years+ - NCT05633810RecruitingPhase 3
Testing colchicine plus coated aspirin to prevent heart events
This Phase 3 study tests whether colchicine and a special type of aspirin can lower the risk of future heart attacks, strokes, or other major heart problems in people with type 2 diabetes who have not had a prior heart event. It aims to reduce cardiovascular risk using medicines that may calm inflammation and protect blood vessels.
Bentley, Western AustraliaAges 55–80 - NCT07243184Recruiting
Polymer heart valve study for mitral valve disease
This trial is testing a new polymer artificial heart valve for people with severe mitral valve problems. It aims to see if this valve is safe and works well during surgical replacement.
BeijingAges 60 years+ - NCT06978998Recruiting
Retinal photos to help predict heart failure outcomes
This study tests whether a simple eye photo can help doctors better predict the course of heart failure with reduced pumping strength. If it works, this low-cost test could improve care for people with this condition.
SeoulAges 20 years+ - NCT06995183Recruiting
Heart CT scan for relatives with high or low Lp(a)
This study uses a heart CT scan to look for early signs of heart disease in first-degree relatives of people with high or low Lp(a). It aims to find hidden risks before symptoms start.
Amsterdam, North HollandAges 50 years+ - NCT07029503RecruitingPhase 2
Heart failure and kidney function study
This trial tests a new treatment for people with heart failure and severely reduced kidney function. It aims to see if the treatment can help protect both the heart and kidneys.
StockholmAges 18 years+ - NCT05279742Enrolling by invitationPhase 1/Phase 2
Study drug to boost a hormone system in HFpEF
This early-phase trial tests a treatment that aims to improve the “natriuretic peptide” hormone system in people with HFpEF (heart failure with preserved pumping strength). It may help reduce symptoms and improve heart and fluid pressure behavior, especially in certain related conditions like kidney disease.
Rochester, MinnesotaAges 18 years+ - NCT06920927Recruiting
Testing an online decision aid for heart and kidney disease
This study is testing an online tool called 'My Heart and CKD' that helps people with both chronic kidney disease and heart disease make decisions about their care. The goal is to see if it is easy to use and helpful for patients and their doctors.
Calgary, AlbertaAges 18 years+ - NCT07560436RecruitingPhase 2
Stents for Heart Failure With Normal Pumping
This trial tests whether placing stents in coronary arteries helps patients with heart failure who still have a strong-pumping heart. The study aims to see if improving blood flow to the heart reduces symptoms and improves quality of life.
LondonAges 18 years+ - NCT01143454Recruiting
Study unusual heart conditions and related genetic traits
This study looks at people with unusual or rare heart problems, or people with a family history of these issues. Doctors and researchers may collect and study your blood or tissue (and possibly store samples) to learn what causes the condition and how it may affect the heart.
Washington D.C., District of ColumbiaAges 1–100 - NCT05236374Recruiting
Daily beef in a heart-healthy diet to study zinc cells
This study tests whether eating daily beef as part of a heart-healthy diet changes how your body’s cells handle zinc, a mineral important for many functions. It’s designed for older adults and includes strict diet and medication rules to keep results accurate.
Davis, CaliforniaAges 55–70 - NCT03685721Recruiting
Study genes in sickle cell disease to compare blood test activity
This study looks at how a person’s genes relate to certain measurements in red blood cells in people with sickle cell disease. The goal is to understand why blood cell function varies and how that might guide future care.
Bethesda, MarylandAges 18–80 - NCT03954574Recruiting
Check blood flow changes in lungs during exercise testing
This study measures how blood moves through your lungs and heart while you exercise, using standard heart-lung pressure measurements. It may help doctors better understand unexplained breathing trouble or suspected pulmonary hypertension and improve how testing and care are guided.
Phoenix, ArizonaAges 18 years+ - NCT07613294RecruitingPhase 3
Testing lepodisiran to reduce heart plaque buildup
This study tests whether a new medicine called lepodisiran can shrink plaque in heart arteries for adults with high Lp(a) (a type of cholesterol linked to heart disease) who have had a heart event or are at serious risk. The trial uses CT scans to monitor changes in your arteries.
La Jolla, CaliforniaAges 45–80 - NCT04976348Recruiting
Heart monitoring registry for teens and adults with heart symptoms
This study registers people who are referred to cardiology or genetics for heart-failure–type symptoms or heart/cardiogenetic screening. It helps doctors understand how monitoring platforms may support diagnosis and follow-up.
Maastricht, LimburgAges 16 years+ - NCT07444931Recruiting
Predicting cardiac arrest risk in heart disease patients
This study looks at factors that may help predict sudden cardiac arrest in people with coronary artery disease. If you have a recent diagnosis of significant blockage or a heart attack, joining this trial could help improve risk assessment.
HaderaAges 18–75 - NCT00001465Recruiting
Understanding lymphangioleiomyomatosis disease progression
This study looks at how lymphangioleiomyomatosis (LAM) affects the lungs over time, using tests like chest imaging and lung biopsies. It aims to learn more about the disease to improve future treatments.
Bethesda, MarylandAges 16–100
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Common questions
- Are there clinical trials for heart diseases?
- Yes. Clin2 currently lists 749 recruiting heart diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.