Clinical trials
Heart Surgery clinical trials
Below are recruiting heart surgery clinical trials, each written for real people, not researchers. We’re tracking 103 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05927233RecruitingPhase 4
Methylprednisolone in children after open-heart surgery
This trial tests whether giving methylprednisolone (a steroid medicine) can lower the body’s inflammatory response in children during the first day after congenital open-heart surgery. It may help reduce harmful inflammation and improve recovery for some children undergoing their first surgery.
Karachi, SindhAges 1 month–18 years - NCT01258231Recruiting
Genetic test to predict risks after heart surgery
This study looks for genetic (DNA) clues that may help predict side effects or complications after heart surgery. If you join, your genome information may be used to understand who is at higher risk and why.
Boston, MassachusettsAges 20–90 - NCT04754022Recruiting
Blood use during heart surgery in younger adults
This study looks at how much donated blood (blood products) is needed for younger adults during heart surgery that uses a heart-lung machine. It may help doctors choose safer, more appropriate blood-saving plans for people like you.
Portland, MaineAges 18–65 - NCT03469440Recruiting
Targeted oxygen monitoring during children’s heart surgery
This trial tests whether a goal-focused monitoring approach can help optimize oxygen levels in the blood during children’s heart surgery using a heart-lung machine. It may help clinicians adjust care more precisely during surgery.
São PauloAges Up to 14 years - NCT06968065Recruiting
Pain control after minimally invasive heart surgery: nerve block vs wound injection
This study compares two ways to manage pain after minimally invasive heart surgery: a nerve block injection near the ribs or injecting numbing medicine into the wound. The goal is to find which method works better for reducing pain and your need for painkillers.
IstanbulAges 18–75 - NCT07424976Enrolling by invitation
Early brain injury detection after infant heart surgery
This study looks for early signs of brain injury in infants after heart surgery that uses a heart-lung machine. It aims to improve monitoring and care for babies with congenital heart disease.
LjubljanaAges 1 week–1 year - NCT06530641RecruitingPhase 4
Comparing heart protection solutions during major heart surgery
This trial compares two types of cardioplegia (a solution that stops your heart during surgery) to see which one leads to better outcomes. It is for adults undergoing major heart surgery with a heart-lung machine.
Madrid, MadridAges 18 years+ - NCT01653223Recruiting
Simvastatin to protect the heart during heart surgery
This trial looks at whether simvastatin (a cholesterol medicine) can help protect the heart during cardiac surgery. You might be invited if you’re having surgery for certain, non-complex heart conditions, but not if you have some specific related health problems.
Guangzhou, GuangdongAges 18 years+ - NCT07391683Recruiting
Heart failure support before heart surgery
This trial tests if special remote care before heart surgery can improve recovery for people with heart failure. You will have regular check-ins by video or phone to help manage your health before your operation.
Innsbruck, TyrolAges 18 years+ - NCT07524998Recruiting
Surgery outcomes for complex heart defects across ages
This study tracks how children and adults with complex heart defects fare after surgery. Researchers want to understand what surgical techniques work best at different ages and how patients recover long-term.
BeijingAges Any age - NCT06616129Recruiting
Geriatric risk assessment for older heart surgery patients
This study tests whether a special geriatric risk assessment and shared decision-making conversation helps older patients (70+) and their doctors choose the best treatment for heart surgery. It aims to improve quality of life by tailoring decisions to each person's health risks.
Groningen, Provincie GroningenAges 70 years+ - NCT06861998Recruiting
Sleep help before heart surgery for infants and toddlers
This trial tests if helping young children with sleep problems before heart surgery can reduce confusion or agitation after surgery. It is for children ages 0 to 3 who have sleep issues and are scheduled for heart repair surgery.
BeijingAges 1 day–3 years - NCT06879431Recruiting
Sleep help before heart surgery for young children
This study tests if helping babies and toddlers with sleep problems sleep better before heart surgery can lower the risk of confusion or agitation after surgery. It is for children aged 0 to 3 years who have trouble sleeping and are scheduled for heart surgery.
BeijingAges 6–12 - NCT04073420Recruiting
Cardiac surgery registry to track Medtronic device outcomes
This registry collects real-world information from people who have had—or plan to have—an eligible Medtronic cardiac surgery device. It aims to better understand how these treatments do over time and help guide future care.
Marietta, GeorgiaAges Any age - NCT06001502Recruiting
Virtual reality for pain and anxiety after heart bypass surgery
This trial tests whether using virtual reality (VR) goggles after heart bypass surgery can help reduce pain and anxiety. If you are having a planned CABG and have no major vision, hearing, or other health issues, you may be eligible.
Amsterdam, North HollandAges 18 years+ - NCT07740915Enrolling by invitation
Pain relief after heart surgery in children
This study compares two types of pain blocks for children having heart surgery for the first time. The goal is to see which block provides better pain relief after surgery, which could help your child recover more comfortably.
Diyarbakır, DiyarbakırAges birth–18 years - NCT03209674Recruiting
Registry tracking outcomes after heart and chest surgery
This is a registry that collects information from people who have heart or chest (thoracic) surgery. It may help doctors understand what improves outcomes after surgery, but it usually does not test a new drug.
Neuilly-sur-Seine, Île-de-France RegionAges Any age - NCT06776822Enrolling by invitation
DNS therapy for asymmetry after heart surgery in children
This trial tests whether a special physical therapy called DNS (Dynamic Neuromuscular Stabilization) can help children aged 6 to 18 who have body asymmetry (uneven movement or posture) after surgery for a congenital heart defect. Participation may improve their balance and muscle control.
PragueAges 6–18 - NCT04217421RecruitingPhase 3
Allopurinol for newborns needing heart surgery with bypass
This trial tests whether the medicine allopurinol can protect the brain and heart in newborns with serious congenital heart disease who need heart surgery soon after birth. It may help reduce injury during and around surgery that uses a heart-lung machine (cardiopulmonary bypass).
GroningenAges Up to 1 month - NCT07677319Recruiting
Heart surgery after age 75: a study on recovery
This study looks at how well people aged 75 and older recover after emergency heart surgery. It uses a special test to measure frailty and quality of life for one year after surgery.
Bordeaux, FranceAges 75 years+ - NCT07662317Recruiting
Heart surgery recovery registry study
This study collects information from people having heart surgery to help doctors learn more about recovery. If you are scheduled for surgery during the study period, you may be able to join.
Hangzhou, ZhejiangAges Any age - NCT07099859RecruitingPhase 4
Losartan after aortic valve surgery for severe leakage
This trial tests if the drug losartan can help the heart recover better after surgery to replace a leaky aortic valve. It may reduce strain on the heart and improve long-term outcomes.
São Paulo, São PauloAges 18–85 - NCT07730034Recruiting
Early physical therapy after heart surgery to prevent breathing problems
This trial tests whether starting physical therapy soon after planned heart surgery can help prevent breathing complications. It is for adults who are having a first-time coronary artery bypass grafting (CABG) and meet specific health criteria.
ZagrebAges 18–80 - NCT07477977Recruiting
Finding the right dose of protamine to reverse heparin after heart bypass
This study is testing different doses of a medication called protamine, which is given after heart surgery to reverse the effects of heparin (a blood thinner). The goal is to find the safest and most effective dose for patients who have had a heart-lung bypass machine during surgery.
SohagAges 18 years+
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Common questions
- Are there clinical trials for heart surgery?
- Yes. Clin2 currently lists 103 recruiting heart surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.