Clinical trials
Heart Surgery clinical trials
Below are recruiting heart surgery clinical trials, each written for real people, not researchers. We’re tracking 103 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06233318Recruiting
Pain block for open heart surgery recovery
This study tests a nerve block given during open heart surgery to improve pain control. It might help patients recover with less discomfort.
Columbus, OhioAges 18 years+ - NCT06828432Enrolling by invitation
Device study for heart surgery patients in the heart intensive care unit
This trial tests a new device that measures heart function closely after heart surgery. It may help doctors give better care if you are in the heart intensive care unit after your operation.
Pittsburgh, PennsylvaniaAges 18–105 - NCT05806346Recruiting
TXA dosing for heart surgery patients on bypass
This trial studies whether giving tranexamic acid (TXA) based on patient needs during heart surgery works better than a one-size-fits-all approach. It may help reduce bleeding during surgery, while monitoring for clotting-related side effects.
SeoulAges 19 years+ - NCT02488876Recruiting
Banking heart tissue samples after cardiac surgery
This study collects tissue samples from people who are having heart surgery and stores them in a database to better understand the body’s inflammatory (immune) response after surgery. Your participation may help researchers learn why inflammation happens and how to improve care after surgery.
Aachen, North Rhine-WestphaliaAges Any age - NCT07588230Recruiting
Nerve Block for Minimally Invasive Heart Valve Surgery Pain
This study tests a targeted nerve block (pain-numbing injection) to help manage pain after minimally invasive heart valve surgery. Researchers want to see if this technique reduces pain and the need for opioid medications during recovery.
Diyarbakır, Outside of the USAges 18–75 - NCT07591987Recruiting
Breathing Techniques to Reduce Shortness of Breath After Heart Surgery
This study tests whether special breathing exercises can help reduce shortness of breath and improve heart and lung function in patients recovering from open-heart surgery. You would learn and practice these breathing techniques before and after your surgery.
Baghdad, Baghdad GovernorateAges 18–75 - NCT07665593Recruiting
AI breathing training after open heart surgery
This trial tests if an AI-assisted breathing exercise device can reduce pain, fatigue, and improve breathing in patients recovering from open heart surgery.
Kocaeli, İzmitAges 18 years+ - NCT07019857Recruiting
Thymus removal and immunity in infant heart surgery
This study looks at how removing the thymus gland during infant heart surgery affects the immune system. It compares babies who have their thymus removed with those who have heart surgery without removing it, and with babies having other types of surgery.
NantesAges Up to 6 months - NCT07405333Recruiting
Coughing exercises vs breathing device after heart surgery in children
This study compares simple coughing exercises with a breathing device (incentive spirometry) to help children recover lung function faster after heart surgery. It may help reduce complications and shorten hospital stays.
Baghdad, Baghdad GovernorateAges 6–18 - NCT04014140Recruiting
iFR-guided bypass surgery planning during elective heart surgery
This trial studies whether using a pressure-measurement test called iFR during a pre-surgery heart scan can help guide coronary artery bypass surgery (CABG). It may improve how doctors choose which artery blockages to treat during planned surgery.
London, Greater LondonAges 25–80 - NCT03536312Recruiting
Surgery versus monitoring for enlarged ascending aorta
This trial compares two ways to treat an enlarged (bigger) ascending aorta: having surgery now versus careful imaging follow-up (surveillance). It may help you and your care team decide which approach lowers the risk of serious problems for aneurysms in a specific size range.
San Francisco, CaliforniaAges 18–79 - NCT07657650Recruiting
Imaging test for heart failure patients before revascularization
This trial uses a special imaging scan to see if heart muscle has damage from blocked arteries. It helps doctors decide if a procedure to open blocked arteries might improve your heart function.
BeijingAges 18 years+ - NCT04216927RecruitingPhase 3
Neonates on heart-lung bypass get NO to prevent kidney injury
This Phase 3 study tests whether not giving nitric oxide during heart-lung bypass in newborns helps reduce the risk of acute kidney injury. It focuses on newborns having heart surgery for congenital heart disease.
Cincinnati, OhioAges 1 day–1 month - NCT04040452RecruitingPhase 4
Continuous versus intermittent ketorolac for kids’ heart surgery pain
This study compares two ways of giving ketorolac (a pain medicine) to young children after heart surgery—continuous drip versus doses at set times. It aims to find which approach controls pain better with fewer side effects.
Phoenix, ArizonaAges 3 months–4.9 years - NCT04299828Recruiting
Study of inflammation activity during complex heart surgery
This study measures how active white blood cells and inflammation are during complex heart surgery using a heart-lung machine. It may help doctors better understand what triggers inflammation during surgery and how to improve care.
Boston, MassachusettsAges Any age - NCT05650307Recruiting
Heart and metabolic scan study of weight and rehabilitation
This study uses detailed heart scans and information about metabolism (how your body uses energy) to understand how metabolic treatments and heart rehabilitation may affect your health. You may qualify either as someone undergoing bariatric (weight-loss) care or as part of a heart rehabilitation group—or as a healthy comparison group.
Cleveland, OhioAges 18 years+ - NCT05658965Recruiting
EEG monitoring after early heart surgery in infants
This study looks at whether early brain-wave testing (EEG) around the time of heart surgery in very young babies can predict later learning and development issues. It may help doctors identify children who need extra support sooner.
Lille, Hauts-de-FranceAges 1 day–1 year - NCT06747546Enrolling by invitation
Oxygen-based blood flow management after heart surgery
This study is testing a new way to manage blood flow after heart surgery in children with congenital heart disease. The goal is to make sure the body gets the right amount of oxygen to help recovery.
Minhang, Shanghai MunicipalityAges 1 week–18 years - NCT06469073Recruiting
Nerve block for pain after heart valve surgery
This study tests a special nerve block (ultrasound-guided) to see if it can better control pain after heart valve replacement surgery. It may help you recover more comfortably if you are having your first mitral or aortic valve replacement.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05996120Recruiting
Finding the best temperature during heart-lung machine surgery
This study looks at the best body temperature to use during heart surgery when a heart-lung machine is needed. You may be able to join if you are having bypass surgery or valve repair, your risk score is moderate or higher, and your surgery is not an emergency.
Leicester, LeicestershireAges 18 years+ - NCT04556188Recruiting
Study to improve cardiac surgery services for rheumatic heart disease
This study looks at whether building a better, sustainable cardiac surgery service can reduce the burden of rheumatic heart disease. It focuses on patients who need cardiac surgery at a specific hospital during a training and research program.
Addis AbabaAges 14 years+ - NCT05687292Recruiting
Decision tool to shorten breathing machine time in children
This study tests whether a computer “decision support” tool can help doctors safely reduce how long a child stays on a breathing machine after heart surgery. It may help children get off mechanical ventilation sooner and recover faster.
Boston, MassachusettsAges 1 day–12 years - NCT05972356Recruiting
How heart relaxation affects outcomes in heart surgery
This study looks at whether a measurement of how well the heart relaxes helps predict outcomes after heart surgery. It focuses on patients treated in Amsterdam UMC and uses care data to understand who may be at higher or lower risk.
Amsterdam, North HollandAges 18 years+ - NCT07414251Recruiting
Preparing children for heart procedures
This study looks at how children prepare for heart surgery or a heart catheterization. It will ask families to fill out questionnaires to help improve preoperative care.
Berlin, State of BerlinAges Up to 18 years
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Common questions
- Are there clinical trials for heart surgery?
- Yes. Clin2 currently lists 103 recruiting heart surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.