Clinical trials
HER2 + Breast Cancer clinical trials
Below are recruiting her2 + breast cancer clinical trials, each written for real people, not researchers. We’re tracking 955 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05913713Recruiting
High-intensity exercise after breast cancer chemotherapy
This study tests whether a structured high-intensity interval exercise program after chemotherapy is safe and helpful for people with early-stage breast cancer. It may improve physical fitness and recovery while they are on typical cancer treatments.
Gainesville, FloridaAges 18–85 - NCT05976815Recruiting
Exercise added to chemotherapy before breast cancer surgery
This study tests whether adding a supervised physical exercise program around the time of “before-surgery” chemotherapy helps people with newly diagnosed breast cancer. You may be assigned to an exercise group or a usual-care group, and the researchers will compare outcomes between them.
Vila Nova de Gaia, Porto DistrictAges 18 years+ - NCT06055881Recruiting
Using radiation to delay changing treatment for breast cancer
This trial tests whether giving radiation to a few growing spots (1-3) can let you stay on your current drug longer, instead of switching to a new one right away. It's for people with metastatic breast cancer whose disease has been stable for months but now shows limited progression.
Scottsdale, ArizonaAges 18 years+ - NCT06067503RecruitingPhase 2
PET scan to detect hormone therapy resistance in breast cancer
This trial tests a new PET scan (called FFNP) to see if it can find which breast cancers stop responding to hormone therapy early. It's for people with advanced hormone-receptor-positive breast cancer who are starting a new endocrine treatment.
Madison, WisconsinAges 18 years+ - NCT06073418Recruiting
Diet, nutrition, and physical activity in early breast cancer
This study looks at the eating habits, nutrition knowledge, and physical activity of women with early-stage breast cancer. It aims to understand how these factors relate to your health and recovery after surgery.
Aviano, PordononeAges 18 years+ - NCT06105684RecruitingPhase 2
Low-dose capecitabine for advanced breast cancer
This trial tests a lower dose of the chemotherapy drug capecitabine in people with advanced breast cancer that is HER2 negative. It aims to see if this gentler dose works well, especially for older or frailer patients who may have more difficulty with standard treatment.
Birmingham, AlabamaAges 60 years+ - NCT06107673RecruitingPhase 2
Pill vs chemo before breast cancer surgery
This study compares taking a daily pill (dalpiciclib with hormone therapy) versus standard chemotherapy before breast cancer surgery. It's for postmenopausal women with a common type of early breast cancer that is strongly hormone-receptor positive and HER2-negative.
Shijiazhuang, HebeiAges 18–75 - NCT06143553RecruitingPhase 3
Paclitaxel micelles for metastatic breast cancer
This trial tests a new form of paclitaxel (a chemotherapy drug) for metastatic breast cancer that is HER2-negative. It may be an option if your cancer has returned or not improved after 2 to 4 previous treatments.
Nanjing, JiangsuAges 18 years+ - NCT06260033RecruitingPhase 2
Radiation Therapy for Oligoprogressive ER+ Breast Cancer
This trial tests whether a precise radiation treatment (SBRT) can target a few growing spots of estrogen receptor-positive breast cancer that has spread to other parts of the body. It also uses a special PET scan (FES PET/CT) to see how well the cancer responds. The goal is to slow down the cancer and delay the need for stronger treatments.
Duarte, CaliforniaAges 18 years+ - NCT06274515RecruitingPhase 4
Study of resistance to breast cancer therapies
This study looks at why some breast cancers stop responding to treatment. It involves taking a small sample of your tumor (biopsy) and blood to understand resistance. If you have HER2-positive or triple-negative breast cancer that is growing despite treatment, you may be able to join.
AnderlechtAges 18 years+ - NCT06282796Recruiting
Early heart risk monitoring for breast cancer chemo
This study tests a method to predict and warn about heart damage from a common type of breast cancer chemotherapy. If you have HER2-positive breast cancer and will receive anthracycline drugs, this trial may help monitor your heart health.
Fuzhou, FujianAges 18–80 - NCT06374459RecruitingPhase 1/Phase 2
Zunsemetinib and capecitabine for breast cancer with bone spread
This trial tests a new drug called zunsemetinib combined with the chemotherapy capecitabine for people with hormone receptor-positive, HER2-negative breast cancer that has spread to the bones. The goal is to see if this combination can better control the cancer.
Westwood, KansasAges 18 years+ - NCT06401421Recruiting
Blood test for tumor DNA after breast cancer chemo
This study tests a new blood test to see if it can find tiny bits of tumor DNA after chemotherapy. If you have a larger or higher-risk breast cancer and are getting chemotherapy before surgery, you may join. The test could help doctors know if your cancer is gone or if more treatment is needed.
Anchorage, AlaskaAges 18 years+ - NCT06404697RecruitingPhase 2
Extra radiation to lymph nodes above collarbone for high-risk breast cancer
This trial tests giving a focused, higher dose of radiation to the lymph nodes above the collarbone after breast cancer treatment. It is for patients whose cancer did not fully disappear from those nodes after pre-surgery chemotherapy, to see if extra radiation can help prevent recurrence.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06409390RecruitingPhase 2
Sequential therapy based on tumor evolution for breast cancer
This trial tests a sequence of different treatments for breast cancer that has spread, based on how the cancer evolves. The goal is to find a personalized treatment plan that may work better over time.
Tampa, FloridaAges 18 years+ - NCT06536881Recruiting
Diet and gut health during breast cancer chemo
This study looks at how changing your diet during chemotherapy affects side effects and your body's energy use. It involves providing stool samples to study gut bacteria.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06811870RecruitingPhase 1/Phase 2
Hyperbaric oxygen before surgery for breast cancer
This trial tests adding hyperbaric oxygen (breathing pure oxygen in a pressurized chamber) before standard chemotherapy for breast cancer. The goal is to see if it helps shrink the tumor more effectively before surgery.
Guangzhou, GuangdongAges 18–60 - NCT06856343Recruiting
Olaparib for early breast cancer treatment study
This study looks at how well the drug Olaparib works in real-world settings for patients with early breast cancer that is HER2-negative. It aims to better understand treatment outcomes.
Clermont-Ferrand, Auvergne-Rh ne-AlpesAges 18 years+ - NCT07007169RecruitingPhase 2
Mediterranean diet study for early breast cancer
This trial tests whether eating a Mediterranean-style diet (rich in vegetables, fruits, whole grains, and healthy fats) can help improve outcomes for women with early breast cancer who are receiving chemotherapy. You will be asked to follow this diet and keep a food diary using an online tool.
EsbjergAges 18 years+ - NCT07020780Recruiting
Short-course radiation for high-risk breast cancer
This trial tests a short, more intense radiation schedule for women with certain breast cancer types or who are under 40. It aims to reduce treatment time while still targeting the whole breast and any high-risk areas.
MilanAges 18–70 - NCT07037199RecruitingPhase 2
A new drug combo for HR+ advanced breast cancer
This trial tests a sequence of three drugs: first trastuzumab rezetecan (a targeted therapy), then a CDK4/6 inhibitor plus hormone therapy. It's for people with a type of breast cancer called HR-positive, HER2-low or ultra-low that has spread or come back and has already progressed on a CDK4/6 inhibitor and hormone therapy.
Guangzhou, GuangdongAges 18 years+ - NCT07049133Recruiting
Tracking side effects of T-DXd for advanced breast cancer
This study looks at people with advanced breast cancer who will receive a drug called T-DXd. Researchers want to understand the side effects of this treatment by analyzing blood samples.
MilanAges 18 years+ - NCT07066917Recruiting
Breast cancer treatment response study
This study looks at how well newer treatments work for advanced or metastatic breast cancer and why some people respond better than others. It is for anyone with HR-positive, HER2-positive/low, or triple-negative breast cancer who has started at least one treatment cycle.
AthensAges 18 years+ - NCT07151911Recruiting
Study of drugs for high-risk early breast cancer
This study looks at the effectiveness of the drugs abemaciclib and olaparib plus hormone therapy for people with high-risk, hormone receptor-positive, HER2-negative early breast cancer. It aims to understand how well these treatments work in real-world settings.
Modena, ModenaAges 18 years+
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Common questions
- Are there clinical trials for her2 + breast cancer?
- Yes. Clin2 currently lists 955 recruiting her2 + breast cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a her2 + breast cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a her2 + breast cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.