Clinical trials
High Grade Glioma (III or IV) clinical trials
Below are recruiting high grade glioma (iii or iv) clinical trials, each written for real people, not researchers. We’re tracking 1,259 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05974462RecruitingPhase 3
Steroids for mild heart inflammation with weaker pumping
This trial tests whether a course of steroid medicine can improve outcomes in people with recently started myocarditis (heart muscle inflammation) and mildly reduced heart pumping. It compares steroids versus placebo (inactive treatment) to see if steroids help the heart recover and prevent worsening.
Edegem, AntwerpAges 18–69 - NCT07202299Recruiting
Weaning preterm babies off high-frequency breathing machines
This trial tests two different ways to safely take preterm babies off a special breathing machine (HFOV). It aims to find which method works better for babies with breathing problems (respiratory distress syndrome).
Al MansurahAges Any age - NCT07198750Recruiting
Pulsed magnetic field therapy for knee osteoarthritis in older adults
This trial tests two types of high-intensity pulsed electromagnetic field therapy (one using two modes, another using one mode) to see if they can reduce pain and improve function in older adults with knee osteoarthritis. You would attend 9 treatment sessions and do exercises at home.
Guadalajara, JaliscoAges 60 years+ - NCT07187531RecruitingPhase 2
Testing a new drug to preserve insulin production in type 1 diabetes
This study tests a new drug called SAB-142, which aims to stop the immune system from attacking insulin-making cells in type 1 diabetes. It may help preserve your body's ability to make insulin. The trial will check if the drug is safe and effective.
San Francisco, CaliforniaAges 5–40 - NCT07185724RecruitingPhase 4
Ketorolac for fresh embryo transfer in IVF
This trial tests whether a medicine called ketorolac (a type of NSAID, similar to ibuprofen) can improve outcomes when you have a fresh embryo transfer during IVF. It may help reduce cramping or inflammation that could affect implantation.
Iowa City, IowaAges 18–37 - NCT07188766Recruiting
Different IV fluid amounts for sickle cell pain crisis
This study compares two ways of giving IV fluids (lighter vs. more fluids) to adults with sickle cell disease who are in the hospital for a painful crisis. The goal is to see which approach helps you feel better sooner.
Dammam, Eastern ProvinceAges 18–60 - NCT07191717RecruitingPhase 2
Imlunestrant and abemaciclib for early ER+ breast cancer
This trial tests whether adding two targeted drugs, imlunestrant and abemaciclib, to your usual hormone therapy can lower the chance of your breast cancer coming back. It is for people with early-stage ER+ breast cancer who have no signs of cancer on scans but have tiny amounts of tumor DNA in their blood (called ctDNA).
Los Angeles, CaliforniaAges 18 years+ - NCT07180511Enrolling by invitationPhase 3
A study of QY201 tablets for moderate to severe eczema
This trial tests a new pill called QY201 for people with moderate to severe atopic dermatitis (eczema) that hasn't responded well to creams. It aims to see if QY201 can help control itching and skin inflammation.
Hangzhou, ZhejiangAges 18–75 - NCT07174310RecruitingPhase 3
Prasinezumab for early Parkinson's disease
This study tests a new medication called prasinezumab, given through a vein (IV), to see if it can slow the progression of early-stage Parkinson's disease. It is for people who are on only one Parkinson's medication and have not yet developed motor complications.
Birmingham, AlabamaAges 50–85 - NCT07155317RecruitingPhase 2
Time-of-day immunotherapy for advanced melanoma
This trial tests whether giving immunotherapy at a specific time of day can improve its effectiveness for advanced melanoma that cannot be removed by surgery. It may help you if you have stage IV melanoma and have not had immunotherapy in the last year.
Atlanta, GeorgiaAges 18 years+ - NCT07164677Recruiting
Nerve block for pain after open-heart surgery
This study tests a nerve block (an injection near the back muscles) to see if it helps control pain after open-heart surgery. It might be a good option if you are having planned heart surgery through a cut in the middle of your chest.
SamsunAges 18–80 - NCT07161414RecruitingPhase 1
Study of rilvegostomig for advanced solid tumors
This study tests a new investigational drug, rilvegostomig, given as an injection under the skin. It is for people with advanced solid tumors that have not responded to or have progressed after standard treatments. The goal is to see how the drug behaves in the body and to assess its safety.
Huntersville, North CarolinaAges 18 years+ - NCT07155187RecruitingPhase 2/Phase 3
Study of telisotuzumab adizutecan for EGFR-mutated lung cancer
This trial tests a new drug, telisotuzumab adizutecan (given through a vein), alone or with another targeted therapy, versus standard treatments for people with a specific type of advanced lung cancer that has an EGFR mutation and has gotten worse after previous treatment.
Springdale, ArkansasAges 18 years+ - NCT05245227RecruitingPhase 3
Prevent heavy bleeding after birth with two medicines versus one
This study tests whether using two medicines at the same time after delivery works better than using one medicine to prevent early heavy bleeding. It may help reduce the chance of postpartum hemorrhage soon after birth.
Stony Brook, New YorkAges 18 years+ - NCT07154706RecruitingPhase 3
Taletrectinib vs placebo after surgery for ROS1-positive lung cancer
This trial tests whether taletrectinib (a targeted pill) can help prevent lung cancer from coming back after surgery in people whose tumors have a ROS1 gene change. You would take either taletrectinib or a placebo (inactive pill) for about a year after surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT06401824RecruitingPhase 2
Combination drug therapy for lung cancer with brain spread
This trial tests a combination of two drugs, sacituzumab govitecan and bevacizumab, for people with a specific type of lung cancer (non-squamous) that has spread to the brain. It aims to see if this treatment can shrink brain tumors and improve outcomes.
AmsterdamAges 18 years+ - NCT07131592RecruitingPhase 4
Tranexamic acid and drain fluid after breast reduction
This study tests whether giving tranexamic acid (a drug that helps blood clot) intravenously or directly into the surgical wound reduces drainage after breast reduction surgery. It may help you heal faster and avoid complications.
Boston, MassachusettsAges 18 years+ - NCT07128589Recruiting
Testing a dental filling material for front teeth repair
This study tests a new flowable composite material that can be used to repair front teeth with class IV cavities or as veneers. The study looks at how well the material works and how satisfied patients are over time.
New York, New YorkAges 18–75 - NCT07116525Recruiting
Study of heart mapping for abnormal rhythms
This trial tests a special catheter to map abnormal heart rhythms like ventricular tachycardia or atrial fibrillation. It may help patients who need a procedure to find and treat the source of these fast or irregular heartbeats.
BrugesAges 18 years+ - NCT07125872RecruitingPhase 2
New drug for relapsed B-cell lymphoma
This trial tests a new treatment for people with B-cell non-Hodgkin lymphoma that has come back after at least two prior treatments. It may help if you've already had rituximab or a similar antibody therapy.
JohannesburgAges 18 years+ - NCT07115992Recruiting
Surgery with or without radiation for prostate cancer
This trial compares radical prostatectomy (surgery to remove the prostate) alone versus surgery plus pelvic lymph node removal, with or without additional radiation, for men with intermediate- or high-risk prostate cancer that has not spread. It aims to see which approach is more effective and safe.
ShanghaiAges 18–80 - NCT07118488Recruiting
New ablation approach for persistent atrial fibrillation with heart issues
This study tests a new way to treat long-lasting atrial fibrillation using focused energy (pulse field ablation) guided by special heart mapping. It may help people who have not improved with medications or have other heart problems like heart failure.
Madrid, MadridAges 18–80 - NCT07116161Recruiting
Exercise and counseling for fatigue in female breast cancer patients
This trial tests if combining exercise with cognitive behavioral therapy (counseling) can help reduce fatigue in women with breast cancer. You may be able to join if you have completed your initial treatments and still feel tired.
SingaporeAges 21 years+ - NCT07119021RecruitingPhase 4
Ultra-early stroke treatment with neuroprotection and clot removal
This trial tests a new approach for treating acute ischemic stroke within 4.5 hours of symptoms starting. It combines a special mobile stroke unit that delivers early brain-protecting medicine with standard clot-busting or clot-removal procedures, to see if this can improve recovery.
BeijingAges 18–80
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Common questions
- Are there clinical trials for high grade glioma (iii or iv)?
- Yes. Clin2 currently lists 1,259 recruiting high grade glioma (iii or iv) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a high grade glioma (iii or iv) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a high grade glioma (iii or iv) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.