Clinical trials
Humans clinical trials
Below are recruiting humans clinical trials, each written for real people, not researchers. We’re tracking 1,243 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05768139RecruitingPhase 1/Phase 2
Testing a new targeted drug for advanced solid tumors with PI3Kα mutation
This trial tests tersolisib, a new targeted medicine, in adults with advanced or hard-to-remove solid cancers. It focuses on tumors that have a specific genetic change (PI3Kα mutation) to see how well the treatment works and what side effects it causes.
Los Angeles, CaliforniaAges 18 years+ - NCT05774561Recruiting
Using blood tests to monitor HPV-related cancer treatment
This study checks whether “liquid biopsies” (blood tests that look for cancer-related signals) can help monitor how HPV-related cancers respond to treatment. It may help doctors spot changes earlier during care.
OlomoucAges 18–99 - NCT05786547RecruitingPhase 3
Varenicline plus support to help quit tobacco in HIV care
This Phase 3 trial tests a quit-smoking program using varenicline (a medicine) plus additional support, for people with HIV who currently use tobacco. It may help you stop smoking or using tobacco and stay quit with safer, guided care.
Aurora, ColoradoAges 18 years+ - NCT05791864RecruitingPhase 1/Phase 2
Gene therapy for vision loss in CLN2, tested for safety
This early-phase trial studies a gene therapy medicine called TTX-381 to see if it is safe and tolerable in people with CLN2 disease that affects the eyes. The study also looks at how well the treatment fits into existing eye enzyme therapy care.
HamburgAges 1–7 - NCT05795257Recruiting
Studying lung immune cells and gut microbes in ARDS
This trial studies how immune cells in the lungs and gut microbes (your microbiome) change during ARDS and how these changes relate to your outcomes. It may help researchers better predict and treat ARDS by learning what’s going on in the lungs and body systems.
HvidovreAges 18 years+ - NCT05802706Recruiting
Study of artery plaque tissue during surgery
This study looks at artery plaque tissue removed during a routine operation (endarterectomy) to better understand diseased vessel changes. You may be able to join if plaque tissue is part of your planned surgery and you can consent.
Limerick, LimerickAges 18 years+ - NCT05805033Recruiting
Dental implant trial testing gum healing with different materials
This study looks at how well the gum tissue “takes” around dental implants when different implant materials are used. It may help improve outcomes for people who need replacement teeth.
LiègeAges 18 years+ - NCT05817734Recruiting
Research study to collect health information from adults
This is a research study that collects information about your health and traits to better understand human health and variation. It is mainly for adults who can consent and do not have several specific medical situations listed below.
RehovotAges 18 years+ - NCT05818410Recruiting
Brain and tech training after below-knee leg loss
This study looks at how your brain works with assistive technology after losing a leg below the knee. It may help researchers improve how prosthetic devices feel and function by measuring brain and movement signals during training.
BrusselsAges 18–65 - NCT05828459RecruitingPhase 1
Testing a new anti-cancer drug in advanced cancers
This early Phase 1 study tests OT-A201 (a first-time-in-humans drug) in people with certain relapsed or advanced cancers. It helps doctors learn the safest dose and how the treatment may work for cancers that have already been treated.
MontpellierAges 18 years+ - NCT05829655RecruitingEarly Phase 1
Measuring drug cravings in people with opioid use disorder
This study tests whether the medication suvorexant can reduce drug cravings in people with opioid use disorder. You will take either suvorexant or a placebo and have your cravings measured in a safe setting.
Baltimore, MarylandAges 18–65 - NCT05838066RecruitingPhase 3
KN026 plus HB1801 for HER2-positive advanced breast cancer
This Phase 3 study tests whether taking KN026 with HB1801 as first treatment works better and is safe for people with HER2-positive breast cancer that has come back or spread. It may help by improving tumor response and delaying progression compared with the study’s treatment plan.
Beijing, chaoyangAges 18 years+ - NCT05843084Recruiting
7-Tesla brain scans to map networks for Parkinson’s DBS
This study uses a very strong MRI (7-tesla) to analyze how parts of the brain connect in people with Parkinson’s who already have deep brain stimulation (DBS). It may help researchers better understand DBS and how it works in the brain.
Amsterdam, North HollandAges 18 years+ - NCT05843786RecruitingPhase 3
Interferon gamma for ventilator pneumonia in ICU
This trial tests whether a medicine called interferon gamma can improve outcomes in adults with a first episode of pneumonia that develops after being on a ventilator in the ICU. It is designed for specific ICU timing, infection severity, and immune marker levels, and it compares treatment on top of standard care.
LimogesAges 18 years+ - NCT05847634Recruiting
Testing how deep sedation affects blood flow in ARDS
This study looks at whether giving deep sedation (and sometimes muscle-paralyzing medicines) changes blood flow and oxygen delivery in the brain during acute respiratory distress syndrome (ARDS). It is a pilot study, meaning it mainly aims to understand safety and gather early information.
Winnipeg, ManitobaAges 18 years+ - NCT05847387Recruiting
Checking endothelial cell health before corneal transplant
This study tests how well a patient’s corneal lining cells are preserved before corneal transplantation, and uses that to guide the transplant approach. It may help improve transplant planning and outcomes for people who need treatment for conditions like keratoconus or Fuchs endothelial dystrophy.
EdegemAges 18 years+ - NCT05847322Recruiting
Pertussis challenge study with delayed antibiotic treatment
This study tests how well a “delayed antibiotic” plan works after being intentionally exposed to pertussis (whooping cough). It aims to learn whether delaying antibiotics for a short time is safe and useful, and you may be treated with an antibiotic if you become symptomatic.
Southampton, HampshireAges 18–55 - NCT05848752Recruiting
Online thinking test study for fluent English speakers
This study uses online tests to study how people make decisions and learn from information. It’s open to adults in the US who perform well on a short pre-test and reliably complete tasks.
Boulder, ColoradoAges 18 years+ - NCT05854615RecruitingPhase 4
Stem cell treatment for painful poor blood flow in limbs
This trial tests whether a stem cell product (Stempeucel®) is safe and effective for people with Buerger’s disease causing critical limb ischemia and foot ulcers. It may help improve healing and blood flow when other options may be limited.
Kuala LumpurAges 18–65 - NCT05855759Recruiting
New graft to help repair large rotator cuff tears
This trial studies a special “acellular” (cell-free) skin-derived graft combined with healing-stimulating materials to improve healing and function after surgery for large rotator cuff tears. It may help people with serious tendon damage in the shoulder, but only if their tear type and health situation fit the study rules.
Bologna, BOAges 18–65 - NCT05857150Recruiting
Study tests exercise effects in adults with obesity
This study looks at how your body responds to exercise if you have obesity. It may help researchers understand which changes happen with exercise and how safe it is for people in your age group.
Rochester, MinnesotaAges 20–45 - NCT05857891Recruiting
Erythropoietin to help clear lung fluid in ARDS
This trial tests whether erythropoietin (EPO), a medicine that affects red blood cell production, can help clear extra fluid from the lungs in people with acute respiratory distress syndrome (ARDS). If it works, it could improve breathing and reduce lung fluid buildup during critical illness.
Wenzhou, ZhejiangAges 18 years+ - NCT05858034Recruiting
Study of aging and frailty in people with HIV over 50
This study looks at what makes some people with HIV become “pre-frail” or frail as they get older. It uses questionnaires and other checks to understand challenges to healthy aging and may help improve future support and care.
Winston-Salem, North CarolinaAges 50 years+ - NCT05871372Recruiting
Study brain circuits behind mood using brain monitoring
This study looks at how brain networks relate to mood and depression by recording brain activity during specific procedures. You may be able to join if you’re already having brain monitoring for epilepsy or are part of a depression deep brain stimulation program.
Houston, TexasAges 21–70
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Common questions
- Are there clinical trials for humans?
- Yes. Clin2 currently lists 1,243 recruiting humans studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a humans trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a humans trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.