Clinical trials · Houston, TX
High blood pressure clinical trials in Houston
We’re tracking 34 recruiting high blood pressure studies with a site in or near Houston — including Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Houston
- NCT06129240Recruiting
Study of a new inhaled treprostinil powder for PH-ILD
This study tests a new dry powder inhaled medicine called LIQ861 for people with pulmonary hypertension related to lung scarring (PH-ILD). If you are already taking an inhaled treprostinil treatment but need better control, this trial may help you switch to a potentially easier-to-use version.
Houston, TexasAges 18–80 - NCT06274801RecruitingPhase 3
Long-term study of seralutinib for pulmonary arterial hypertension
This trial is for people with pulmonary arterial hypertension (PAH) who have already completed a previous study of the drug seralutinib. It offers continued access to the treatment so doctors can watch its safety and effects over a longer time.
Houston, TexasAges 18–75 - NCT07288398RecruitingPhase 3
Levosimendan for exercise limitation in PH-HFpEF
This trial tests if the drug levosimendan can help people with a specific type of pulmonary hypertension (PH-HFpEF) feel less tired and breathless during daily activities, and improve their exercise ability.
Houston, TexasAges 18–85 - NCT05401357RecruitingPhase 3
Test eye drops for glaucoma or high eye pressure in both eyes
This Phase 3 study compares two versions of the same glaucoma eye-drop medicine (bimatoprost 0.01%) to see how similarly they work and their effect on eye pressure. It may help people with chronic open-angle glaucoma or ocular hypertension who need treatment in both eyes.
Houston, TexasAges 18 years+ - NCT05889650Recruiting
External drainage for severe TBI brain swelling
This study tests whether placing an external drainage tube in the lower back can reduce dangerous pressure in the brain after a severe traumatic brain injury. If you meet safety and brain-scan criteria, it may help the research team understand whether this approach is safe early after injury.
Houston, TexasAges 18–65 - NCT07064473RecruitingPhase 3
Testing vicadrostat plus empagliflozin for diabetes, high blood pressure, and heart disease
This study tests a new pill called vicadrostat taken with another medicine (empagliflozin) to see if it helps people with type 2 diabetes, high blood pressure, and heart disease. It may reduce the risk of heart problems, but you must not have had heart failure or use certain other heart medications.
Houston, TexasAges 18 years+ - NCT07610278RecruitingPhase 2
Blood Pressure and Cholesterol Treatment Study
This study tests a combination of two new medications (QCZ484 and inclisiran) designed to lower both blood pressure and cholesterol levels. You may be a good fit if you have high blood pressure and high cholesterol that isn't fully controlled by current treatments.
Houston, TexasAges 18–75 - NCT06559891Recruiting
Ultrasound treatment for high blood pressure
This trial tests an ultrasound device that targets nerves around the kidney to lower blood pressure. It may help people whose blood pressure is not well controlled with medication.
Houston, TexasAges 22–75 - NCT06823115Enrolling by invitation
Worldwide study of kidney injury in newborns
This study looks at how common acute kidney injury is in newborns in the intensive care unit. It helps doctors understand which babies are at risk and how to prevent kidney problems.
Houston, TexasAges birth–2 weeks - NCT06267274RecruitingPhase 1
Comparing two forms of bimatoprost for glaucoma or high eye pressure
This trial tests whether a new formulation of bimatoprost works as well as an existing one to lower eye pressure in people with chronic open-angle glaucoma or ocular hypertension. It involves multiple eye drop doses and checks for safety and effectiveness.
Houston, TexasAges 18 years+ - NCT06911632Recruiting
AI-assisted check for pulmonary hypertension in interstitial lung disease
This study uses an AI tool to help doctors decide if you should be tested for pulmonary hypertension (high blood pressure in the lungs), which can be a complication of interstitial lung disease. If the tool suggests you might have it, you may get an echocardiogram (an ultrasound of the heart) and a right heart catheterization (a test to measure pressure in the heart) to find out for sure.
Houston, TexasAges 18 years+ - NCT07218029RecruitingPhase 3
Long-term study of sotatercept for PAH
This study is for people who have already taken part in a clinical trial of sotatercept for pulmonary arterial hypertension and done well enough to continue. It tests the long-term safety and effectiveness of staying on sotatercept, an investigational treatment that helps lower blood pressure in the lungs.
Houston, TexasAges 18 years+ - NCT07175038RecruitingPhase 2
Study of a new pill for pulmonary hypertension
This study tests a new pill, ROC-101, for people with pulmonary hypertension (high blood pressure in the lungs). It aims to see if the pill can improve symptoms and daily function.
Houston, TexasAges 18–80 - NCT06843577Recruiting
Handgrip therapy for high blood pressure
This trial tests if a simple handgrip exercise device can help lower blood pressure in people with elevated blood pressure or hypertension. You will use the device at home and have regular check-ups to see how well it works.
Houston, TexasAges 22 years+ - NCT06388421Recruiting
PH-ILD patient registry: tracking real-world outcomes
This study tracks people with both lung scarring and high blood pressure in the lungs (Group 3 PH-ILD) to better understand the disease and how treatments like Tyvaso work in real life. It may help you and your doctor make more informed decisions about your care.
Houston, TexasAges 18 years+ - NCT06052072Enrolling by invitation
Heart failure trial testing nerve treatment for lung pressure
This trial tests a new treatment that uses a device to calm overactive nerves in the lung's blood vessels. It is for heart failure patients who also have high blood pressure in their lungs, to see if it can help them breathe easier and feel better.
Houston, TexasAges 22–85 - NCT07413159Recruiting
Check, monitor, control hypertension study
This 24-month trial tests whether combining pharmacist counseling with community health worker support helps African Americans aged 55+ better control their high blood pressure. You will receive extra guidance to manage your blood pressure at home.
Houston, TexasAges 55 years+ - NCT06468202RecruitingPhase 4
Aspirin dose study to prevent high blood pressure in pregnancy
This trial compares two doses of aspirin to see which is better at preventing conditions like preeclampsia (a serious form of high blood pressure during pregnancy). You may qualify if you are in early pregnancy and have certain risk factors.
Houston, TexasAges 14–35 - NCT06742723RecruitingPhase 3
Study of baxdrostat and dapagliflozin for kidney disease and high blood pressure
This trial tests if combining baxdrostat with dapagliflozin helps protect kidney function and reduce heart risks in people with chronic kidney disease and high blood pressure. It's for adults who are already taking standard blood pressure medications.
Houston, TexasAges 18 years+ - NCT07218783RecruitingPhase 3
Testing a new glaucoma implant with cataract surgery
This trial tests a new implant that releases medicine for glaucoma while you have cataract surgery. It may help lower eye pressure without using daily drops.
Houston, TexasAges 22 years+ - NCT07181109RecruitingPhase 3
Study of zilebesiran for high-risk hypertension patients
This trial tests a new medicine called zilebesiran for people with high blood pressure that isn't well controlled. It may be an option if you have heart or blood vessel disease, or are at high risk for it.
Houston, TexasAges 18 years+ - NCT03683186Enrolling by invitationPhase 3
Long-term study of ralinepag for pulmonary hypertension
This study follows people with pulmonary arterial hypertension (PAH) to see how safe and effective ralinepag is over the long term. It may help your care team understand what to expect from continued treatment and monitoring.
Houston, TexasAges 18 years+ - NCT06343298RecruitingPhase 2
Testing MANP for hard-to-control high blood pressure
This trial tests a new drug called MANP for people whose blood pressure stays high despite taking three or more different types of blood pressure medications. The goal is to see if MANP is safe and effective in lowering blood pressure.
Houston, TexasAges 18–80 - NCT07661329RecruitingPhase 3
Comparing a new eye drop to a standard one for glaucoma and high eye pressure
This study tests a new eye drop against an existing one to see which better lowers eye pressure in people with open-angle glaucoma or ocular hypertension. You may be able to join if you have high eye pressure in both eyes that needs treatment and you are at least 18 years old.
Houston, TexasAges 18 years+
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High blood pressure trials in other cities
Where these studies are running near Houston
Institutions with a site for the recruiting high blood pressure studies listed above.
- Houston Methodist Hospital · 7 studies
- Houston Eye Associates · 4 studies
- Baylor College of Medicine · 3 studies
- Aavon Clinical Trials · 2 studies
- CHI St. Luke's Health Baylor College of Medicine Medical Center
- Clinical Trial Site
- East Texas Cardiology PA
- Houston Medical Center
What taking part in a high blood pressure study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting high blood pressure studies in Texas.
Common questions
- Are there high blood pressure clinical trials near Houston?
- Yes. We're currently tracking 34 recruiting high blood pressure studies with a site near Houston, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a high blood pressure study near Houston?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Houston to take part?
- Not necessarily. These studies have a site near Houston, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New high blood pressure studies open near Houston regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.