Clinical trials
High blood pressure clinical trials
Persistently raised blood pressure, a major risk factor for heart disease and stroke. We’re tracking 980 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07453550Recruiting
Exercise and Blood Pressure Study
This study tests whether short periods of exercise can lower blood pressure. It is for adults with slightly elevated blood pressure who are not on medication and do not smoke or have certain health conditions.
West Hartford, ConnecticutAges 18–55 - NCT07450222Enrolling by invitation
Improving high blood pressure care
This trial studies a new way to help people with high blood pressure get better control of their numbers. It uses a team approach to support you in managing your blood pressure and lowering your risk for heart problems.
Peoria, IllinoisAges 18 years+ - NCT07439380Recruiting
Group care for high blood pressure and diabetes in Nepal
This trial tests whether group-based care can help people manage high blood pressure or diabetes better than standard care. If you live in one of the study areas in Nepal and have high blood pressure or diabetes, you may be able to join.
DhulikhelAges 18 years+ - NCT06362382Recruiting
Home rehab via smartphone for pulmonary hypertension
This study tests whether a home-based exercise program, guided by a smartphone app, can improve your daily life and heart function if you have pulmonary hypertension. You will use a wearable device to track your activity and receive remote support from a medical team.
Beijing, Beijing MunicipalityAges 18–60 - NCT07420907Recruiting
Tracking heart health over time
This study uses a wearable patch to monitor heart-related signs in people with heart conditions. It aims to learn more about how these conditions progress, which could help improve future care.
Chicago, IllinoisAges 18 years+ - NCT07419724Recruiting
Portal hypertension biobank study
This study collects medical data and images from people with portal hypertension who have enlarged veins in the esophagus or stomach. It aims to build a database for future research.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07420465Recruiting
Heart and metabolic risks in pregnancy and after birth
This study looks at heart and metabolic health during late pregnancy and after delivery, tracking both healthy women and those with complications like high blood pressure or diabetes in pregnancy. The goal is to understand how these risks change and what can be done to improve long-term health.
AccraAges 18–45 - NCT07424963Recruiting
Comparing two ways to measure liver pressure
This study compares a newer, less invasive method using an endoscope (EUS-PPG) with a standard catheter method (HVPG) to measure liver pressure in people with advanced liver disease. The goal is to see if the newer method is equally accurate and safer.
Prague, BohemiaAges 18–75 - NCT05166954Recruiting
Bariatric surgery and heart function in people with high blood pressure
This study looks at whether bariatric (weight-loss) surgery improves heart function in people who have high blood pressure. You may be able to join if you’re already a bariatric surgery patient at the study hospital and meet the health and medication criteria.
Beijing, Beijing MunicipalityAges 17–70 - NCT05498675Recruiting
Sacubitril/valsartan study for high blood pressure by body size
This study tests how sacubitril/valsartan may affect heart function in people with high blood pressure, and whether results differ by body size (BMI). You may benefit by getting closer heart monitoring, though it depends on whether you fit the safety and medical criteria.
Beijing, Beijing MunicipalityAges 18–70 - NCT07400549Recruiting
Exercise plan study for people with high blood pressure, blood sugar, cholesterol, or uric acid
This study tests a tool that helps doctors create personalized exercise plans for people with conditions like high blood pressure, diabetes, high cholesterol, or high uric acid (the "Four Highs"). It could help you stay active and manage your health better.
BeijingAges 18 years+ - NCT06826872RecruitingPhase 2
Testing SPC1001 for essential hypertension
This trial tests an oral medication called SPC1001 to see if it can safely lower blood pressure in people with essential hypertension (high blood pressure not caused by another condition). It may help if you have mild to moderate high blood pressure.
SeoulAges 19–75 - NCT06829134Recruiting
Kidney nerve block for high blood pressure during surgery
This trial tests if numbing the nerves around the kidney artery during laparoscopic surgery can better control high blood pressure. It is for people already needing surgery for certain kidney or adrenal conditions who also have hypertension.
ShanghaiAges 18–75 - NCT07397260Enrolling by invitation
Home blood pressure monitoring and feedback for hypertension
This trial tests whether sending your home blood pressure readings to your doctor and getting automatic feedback helps manage high blood pressure. You'll use a blood pressure monitor at home and share results through a patient portal.
Chicago, IllinoisAges 18–84 - NCT02057783Recruiting
Exercise program to lower blood pressure in sleep apnea
This trial tests whether a supervised physical activity program can help lower blood pressure in people with obstructive sleep apnea and resistant high blood pressure. It may help you control blood pressure when it has not improved despite multiple medications.
QuébecAges 18–80 - NCT07366879Recruiting
Exercise program for newly diagnosed pulmonary hypertension
This study tests whether a home-based exercise program, added to your regular medications, can help people who are newly diagnosed with pulmonary arterial hypertension feel better and improve their daily function.
GlasgowAges 18 years+ - NCT07363343Recruiting
Blood pressure medication study for new mothers after birth
This study tests two different drug combinations to see which works better for new mothers with postpartum high blood pressure that needs more than one medication.
Cleveland, OhioAges 18 years+ - NCT07365332RecruitingPhase 3
IKT-001 for pulmonary arterial hypertension
This study tests a new medicine called IKT-001 for people with pulmonary arterial hypertension (PAH). It aims to see if IKT-001 helps improve exercise ability and other symptoms when added to current PAH therapies.
Scottsdale, ArizonaAges 18–75 - NCT07368608RecruitingPhase 1/Phase 2
Testing a new drug for high blood pressure and cholesterol
This study tests a new medicine called BEBT-701 for people with mild to moderate high blood pressure and high cholesterol. The goal is to see if it can lower both blood pressure and LDL ('bad') cholesterol safely.
Changsha, HunanAges 18–60 - NCT04974151RecruitingPhase 4
Prevention trial for stroke risk in people with high blood pressure
This trial tests an approach to prevent first-time stroke and heart problems in people with high blood pressure who also have a specific genetic test result (MTHFR 677 TT). It may help by lowering risk before a first stroke happens.
Bengbu, AnhuiAges 45–74 - NCT04974138RecruitingPhase 4
Preventing first stroke in people with high-risk blood pressure
This trial tests whether a study medicine regimen can help prevent a first stroke in people with hard-to-control “high homocysteine” risk factors linked to a specific gene type. You may qualify if you have certain blood pressure levels, a specific MTHFR gene result, and related blood test findings.
Bengbu, AnhuiAges 45–74 - NCT07361276Recruiting
Observational study on high blood pressure treatment in public clinics
This study looks at how doctors treat high blood pressure in public health clinics. By reviewing medical records, researchers hope to understand what treatments are used and how well they work.
FlorianópolisAges 18 years+ - NCT07361679RecruitingPhase 4
Aspirin plus heparin vs aspirin alone for preeclampsia prevention
This trial tests whether adding a daily blood-thinning injection (heparin) to low-dose aspirin helps prevent preeclampsia better than aspirin alone for pregnant women at high risk.
Athens, AtticaAges 18 years+ - NCT07359599RecruitingPhase 4
IV iron for exercise and quality of life in pulmonary hypertension
This study tests whether intravenous (IV) iron can help people with pulmonary hypertension feel better, have more energy, and enjoy a better quality of life. You may qualify if you have a type of pulmonary hypertension and low iron levels.
AalstAges 18 years+
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Common questions
- Are there clinical trials for high blood pressure?
- Yes. Clin2 currently lists 980 recruiting high blood pressure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a high blood pressure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.