Clinical trials
High blood pressure clinical trials
Persistently raised blood pressure, a major risk factor for heart disease and stroke. We’re tracking 990 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05184933Recruiting
Study sleep timing and blood pressure patterns in adults
This study looks at how your sleep schedule and body clock relate to blood pressure control. You may be asked to follow a study plan that helps researchers understand what sleep and daily timing changes do to hypertension.
Portland, OregonAges 25–64 - NCT05234788Recruiting
Radial-access kidney nerve procedure for hard-to-control high blood pressure
This trial tests a procedure that uses a catheter through the wrist or thigh to quiet overactive nerves in the kidney artery. It aims to lower blood pressure in people whose high blood pressure stays uncontrolled despite using multiple blood pressure medicines.
BordeauxAges 18–75 - NCT05309460RecruitingPhase 4
Labetalol or nifedipine to treat postpartum high blood pressure
This study compares two common blood pressure medicines—labetalol and nifedipine—to control high blood pressure after childbirth. It may help you and your care team find the safest way to bring your blood pressure back to normal after delivery.
Omaha, NebraskaAges 19 years+ - NCT05329714Recruiting
Deep testing registry for people with pulmonary hypertension
This trial is a global registry that collects detailed health information (“deep phenotyping”) from people diagnosed with pulmonary hypertension. It helps researchers better understand the condition and how people differ, which can guide better future treatments.
Giessen, HesseAges Any age - NCT05340023Recruiting
Test using lung scan patterns to diagnose a heart-lung condition
This study looks at patterns from specialized lung scan tests to help diagnose chronic thromboembolic pulmonary hypertension (a long-term problem with blood flow in the lungs after blood clots). If your results suggest this condition and you need a procedure to check heart pressure, you may be asked to join so the researchers can improve diagnosis.
Saint-EtienneAges 18 years+ - NCT05372263Recruiting
Tracking safety of pulmonary hypertension medicines by computer follow-up
This study checks how safe pulmonary hypertension–targeted medicines (and some calcium-blocking medicines) are over time. It uses a computer system to follow you after diagnosis, looking at outcomes and side effects.
Beijing, Beijing MunicipalityAges 3 months–85 years - NCT05401357RecruitingPhase 3
Test eye drops for glaucoma or high eye pressure in both eyes
This Phase 3 study compares two versions of the same glaucoma eye-drop medicine (bimatoprost 0.01%) to see how similarly they work and their effect on eye pressure. It may help people with chronic open-angle glaucoma or ocular hypertension who need treatment in both eyes.
Newport Beach, CaliforniaAges 18 years+ - NCT05421767RecruitingPhase 4
Renal nerve stimulation for hard-to-control high blood pressure
This trial tests whether stimulating nerves around the kidney can lower blood pressure in people whose high blood pressure stays uncontrolled despite treatment. It may help by improving how the kidneys and blood vessels regulate blood pressure.
TaipeiAges 20 years+ - NCT05434195Recruiting
Study folate in pregnancies with high blood pressure
This study looks at how a vitamin called tetrahydrofolate may affect pregnancies with preeclampsia or increased risk of high blood pressure. Participants may receive the supplement to help researchers understand key biology and potential benefits or harms.
Oxford, OxfordhsireAges 18–45 - NCT05442671Recruiting
Exercise coaching program for children with pulmonary hypertension
This trial tests whether a structured exercise program, done with remote support, is safe and helpful for children with pulmonary hypertension. It aims to improve how well kids function day-to-day while they stay on their usual PH medications.
Philadelphia, PennsylvaniaAges 8–18 - NCT05464095Recruiting
Mobile health support for pulmonary arterial hypertension
This study tests whether using a mobile health tool can help people with pulmonary arterial hypertension (PAH) manage their condition in daily life. It’s aimed at adults who are stable on their PAH medicines and can track activity using a wearable device.
Nashville, TennesseeAges 18 years+ - NCT05470205RecruitingPhase 3
Noninvasive blood-pressure measurement to estimate liver portal pressure
This Phase 3 study tests a noninvasive ultrasound-based method to estimate portal hypertension, which is high blood pressure in the liver’s blood vessels. It aims to help doctors measure how severe the liver circulation problem is without needing invasive pressure testing.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05475015Recruiting
3D MRI scan to assess liver scarring and pressure
This study tests whether a special 3D MRI scan (3D-MRE) can measure liver scarring and the high pressure in the liver called portal hypertension. It may help your team use imaging to understand how severe your liver disease is, especially when a pressure test (HVPG) is being considered.
Shenyang, LiaoningAges 18–75 - NCT05479461Recruiting
Phone-based blood pressure care vs usual care
This trial tests whether a technology-enabled program (using a smartphone) helps lower blood pressure better than standard care. It may help you manage high blood pressure with guided treatment changes.
Palo Alto, CaliforniaAges 30–90 - NCT05489575Recruiting
CPAP machine for high blood pressure when lying down at night
This study tests whether using a CPAP breathing machine at night can lower high blood pressure that happens while you sleep. It targets people with nervous-system problems that affect blood pressure changes when standing.
Nashville, TennesseeAges 40–80 - NCT05498675Recruiting
Sacubitril/valsartan study for high blood pressure by body size
This study tests how sacubitril/valsartan may affect heart function in people with high blood pressure, and whether results differ by body size (BMI). You may benefit by getting closer heart monitoring, though it depends on whether you fit the safety and medical criteria.
Beijing, Beijing MunicipalityAges 18–70 - NCT05530512Recruiting
Acupuncture for mild to moderate high blood pressure
This study tests whether acupuncture can help lower blood pressure in people with mild to moderate hypertension. You may be asked to join because you meet age and blood-pressure ranges and have a normal heart screening ECG.
Irvine, CaliforniaAges 45–75 - NCT05546931Recruiting
Mobile health program to help control high blood pressure
This study tests a phone-based (mobile) health program to help people in rural areas better control high blood pressure. It may help you track your readings and follow a plan that supports safer blood pressure over time.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05551104RecruitingPhase 3
Best blood pressure medicine after pregnancy
This study compares two common blood pressure medicines (nifedipine and labetalol) to see which is safest and works best for high blood pressure after childbirth. If you have postpartum hypertension, the trial may offer close monitoring and help doctors choose the safest option for you.
Loma Linda, CaliforniaAges 18 years+ - NCT05563337Recruiting
Renal denervation for young women with high blood pressure
This study tests a procedure called renal denervation to help lower blood pressure in young women with high blood pressure that’s not too severe. The goal is to see if the treatment can improve blood pressure control safely.
BordeauxAges 18–40 - NCT05587712RecruitingPhase 2
Sotatercept trial for children with pulmonary arterial hypertension
This Phase 2 trial tests sotatercept, a medicine that targets the blood-vessel changes in pulmonary arterial hypertension (PAH), in children. It may help improve how well the heart and lungs work by changing the underlying disease process.
Los Angeles, CaliforniaAges 1–17 - NCT05590871Recruiting
Kidney nerve ablation to treat hard-to-control blood pressure
This trial tests a procedure that targets nerves near the kidney (renal denervation) to help lower blood pressure in people whose hypertension is not controlled despite medication. It uses a special 3D mapping system to guide the procedure.
Chongqing, Chongqing MunicipalityAges 18–70 - NCT05593055RecruitingPhase 4
Test a heart and blood-pressure therapy in people with hypertension
This study looks at how mineralocorticoid-related hormone signaling affects small heart blood vessels and how efficiently the heart works in people with high blood pressure. It may help doctors understand which treatments could improve heart function in hypertension.
Boston, MassachusettsAges 18–75 - NCT05610631Recruiting
Switzerland heart-lung pressure registry for people with PH
This is a registry that collects information from people who have pulmonary hypertension (high blood pressure in the lungs). It helps researchers better understand the condition and may support future studies.
ZurichAges Any age
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Common questions
- Are there clinical trials for high blood pressure?
- Yes. Clin2 currently lists 990 recruiting high blood pressure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a high blood pressure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.