Clinical trials
High blood pressure clinical trials
Persistently raised blood pressure, a major risk factor for heart disease and stroke. We’re tracking 980 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07177989Recruiting
Breathing and exercise for better blood pressure
This study tests whether combining a special breathing technique with aerobic interval training (short bursts of exercise) can help lower blood pressure and heart strain in people with hypertension. It may offer a safe, drug-free way to manage your condition.
RawalpindiAges 25–50 - NCT07179380RecruitingPhase 3
Inhaled treprostinil for pulmonary hypertension related to interstitial lung disease
This study tests an inhaled powder medication called TPIP (treprostinil palmitil inhalation powder) to see if it can improve symptoms and exercise ability in people who have both interstitial lung disease and pulmonary hypertension. The study will compare TPIP against a placebo (a dummy treatment without the active drug) to understand how well it works and if it is safe.
Phoenix, ArizonaAges 18 years+ - NCT04484675RecruitingPhase 4
Milrinone during heart surgery for severe pulmonary hypertension
This trial tests whether giving milrinone through a vein and inhaled during mitral valve surgery helps people with severe pulmonary hypertension. The goal is to improve heart and lung blood-flow stability around the time of surgery.
Zagazig, Sharqia ProvinceAges 18 years+ - NCT07163689Recruiting
TIPS for liver disease with portal hypertension
This trial compares patients who have a rare liver condition (porto-sinusoidal vascular disease) with those who have cirrhosis, to see how a procedure called TIPS (a shunt placed in the liver to reduce blood pressure) works for complications like bleeding, fluid buildup, or blood clots.
Amiens, PicardieAges 18 years+ - NCT06950099Recruiting
Advanced Brain Scans for IIH Patients Planning Stenting
This study uses advanced brain scans (MRIs) to look at the veins in your brain to help plan a stenting procedure for patients with Idiopathic Intracranial Hypertension (IIH) that is not improving with standard care.
Philadelphia, PennsylvaniaAges 18–55 - NCT07147075Enrolling by invitation
Improving blood pressure care through better doctor-patient talks
This study tests a training program for doctors to help them communicate better with patients who have high blood pressure. If you have high blood pressure and see a doctor at certain Duke Primary Care clinics, you may be able to join.
Durham, North CarolinaAges 18 years+ - NCT07151768Recruiting
Validating a risk score for lung disease patients with pulmonary hypertension
This study is testing whether a new risk score can better predict outcomes for people who have both chronic lung disease and pulmonary hypertension (high blood pressure in the lungs). If you qualify, the researchers will follow your health over time to see how well the score works.
Philadelphia, PennsylvaniaAges 18–99 - NCT07149935Recruiting
Exercise training for pulmonary arterial hypertension
This study tests whether a special exercise training program can help people with pulmonary arterial hypertension (PAH) feel better and stay stable. If you have mild-to-moderate PAH and are on stable medication, you may be able to join.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07154927Recruiting
Using ultrasound to guide heart catheterization for pulmonary hypertension
This trial tests if using ultrasound to guide a catheter into the lung's blood vessels is a good way to diagnose pulmonary hypertension. It may help find a safer, more accurate method for diagnosis.
Asyut, Select A StateAges Any age - NCT07143448RecruitingPhase 1/Phase 2
Study of HS235 for pulmonary arterial hypertension in adults
This trial tests an experimental drug called HS235 for people with pulmonary arterial hypertension (PAH), a condition of high blood pressure in the lungs. It aims to see if the drug can help improve symptoms and exercise ability.
Tampa, FloridaAges 18 years+ - NCT07142356RecruitingPhase 2
New oral medication for high blood pressure not controlled by current pills
This study tests a new medication, RTN-001, for people whose blood pressure remains high even when taking multiple blood pressure medications. The goal is to see if this drug can lower blood pressure more effectively.
Alexander City, AlabamaAges 18–75 - NCT07136623Recruiting
Can a smart stethoscope detect pulmonary hypertension?
This study is testing if a special digital stethoscope (CORE 500) can help detect a heart condition called pulmonary hypertension. You may join if you are 18 or older, not currently hospitalized, and will have a heart ultrasound or right heart catheterization around the time of your visit.
Los Angeles, CaliforniaAges 18 years+ - NCT07140484RecruitingPhase 4
Sotatercept for pulmonary arterial hypertension
This study tests a new medication called sotatercept for people with pulmonary arterial hypertension (PAH) who are already on at least two other PAH treatments. The goal is to see if adding sotatercept can improve symptoms and exercise ability.
Edmonton, AlbertaAges 18 years+ - NCT07130955Enrolling by invitation
Ablation for hard-to-control high blood pressure with kidney disease
This study tests a new device that uses energy to calm kidney nerves, which may help lower blood pressure in people with chronic kidney disease whose blood pressure stays high despite taking multiple medications.
Beijing, Beijing MunicipalityAges 18–65 - NCT07131241Recruiting
A study to predict risk in pulmonary hypertension
This study aims to better predict the future risk for people with pulmonary hypertension (high blood pressure in the lungs) by combining different types of health information collected over time. If you join, researchers will track your health data to build a tool that personalizes care and improves outcomes.
Fuzhou, FujianAges 18 years+ - NCT07131748Recruiting
Water vs. land exercise for older adults with high blood pressure
This study compares the effects of exercising in heated water versus exercising on land for older adults with high blood pressure. It looks at how each type of exercise affects blood pressure, physical fitness, and quality of life.
Bauru, São PauloAges 60 years+ - NCT07135505Recruiting
Time-restricted eating for older adults with high blood pressure
This trial studies whether eating only during a shorter time window each day (time-restricted eating) can help older adults with high blood pressure. It explores a simple daily eating pattern to see if it lowers blood pressure and improves health.
Birmingham, AlabamaAges 60 years+ - NCT07123779RecruitingPhase 1/Phase 2
Study of a new drug for heart failure with pulmonary hypertension
This study tests an investigational drug (HS235) for people who have both heart failure with preserved ejection fraction and a type of pulmonary hypertension that can happen with it. The goal is to see if the drug can improve symptoms and quality of life.
Kansas City, MissouriAges 18 years+ - NCT07125313Recruiting
Yoga for heart and mind health in hypertension
This trial tests whether yoga can improve heart and mental health in people with high blood pressure. It is for adults who have their blood pressure under control with up to three medications and have not exercised in the last six months.
Florianópolis, Santa CatarinaAges 18 years+ - NCT07122622Recruiting
Spleen stiffness test to check for dangerous veins in the liver
This trial uses a non-invasive ultrasound test to measure spleen stiffness, which may help find problems with blood pressure in the liver and identify enlarged veins that can bleed. It could help avoid more invasive tests.
Roma, ItaliaAges 18 years+ - NCT04755764Recruiting
Compare blood-pressure medicines in early pregnancy
This trial tests how three common blood-pressure medicines (labetalol, atenolol, and nifedipine) affect blood flow in early pregnancy. It may help doctors choose the safest, most effective option for pregnant people with high blood pressure.
Huntington, West VirginiaAges 18–45 - NCT07099144Recruiting
Inhaled nitric oxide for newborns with breathing failure and high blood pressure in the lungs
This trial tests whether inhaled nitric oxide gas can help full-term newborns who have severe breathing problems and high blood pressure in their lungs. It aims to improve oxygen levels and reduce the need for more intensive support.
Guangzhou, GuangdongAges Up to 1 week - NCT06970509Recruiting
Improving treatment for stomach bleeding from liver disease
This trial studies better ways to use endoscopy and other treatments to stop bleeding in the stomach or esophagus caused by high blood pressure in the liver (portal hypertension). It may help if you have been diagnosed with portal hypertension and have varices (enlarged veins) in your esophagus or stomach.
Guangzhou, GuangdongAges 18 years+ - NCT07087613Recruiting
Detecting heart and lung pressure problems with a smart stethoscope
This study tests if a digital stethoscope and a simple 3-lead ECG (heart rhythm test) can detect two heart conditions: high blood pressure in the lungs (pulmonary hypertension) and low pumping strength of the heart (low ejection fraction). It's intended for adults who recently had a heart ultrasound or a heart catheterization.
O'Fallon, IllinoisAges 18 years+
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Common questions
- Are there clinical trials for high blood pressure?
- Yes. Clin2 currently lists 980 recruiting high blood pressure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a high blood pressure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.