Clinical trials
High blood pressure clinical trials
Persistently raised blood pressure, a major risk factor for heart disease and stroke. We’re tracking 980 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07725250Recruiting
AI-guided blood pressure trial for stage I-II hypertension
This study tests whether combining artificial intelligence with personalized medicine can help lower blood pressure in people with stage I or II hypertension (140/90 or higher). If you have high blood pressure and can walk without help, this trial may be for you.
La Jolla, CaliforniaAges 18 years+ - NCT03781401Recruiting
Blood pressure monitoring at local pharmacies
This trial studies using a telemedicine system to check blood pressure in community pharmacies. It may help people with known high blood pressure (treated or untreated) get safer, more convenient monitoring.
Solbiate ArnoAges Any age - NCT07719660Recruiting
Wearable blood pressure monitor comparison study
This study compares a wearable blood pressure monitor to standard measurements. It needs people whose arm can be used for a cuff and who can give consent, and some participants are in the ICU.
Dresden, SaxonyAges 21–85 - NCT07713121Recruiting
Keeping blood pressure up during surgery to prevent confusion in older adults
This trial tests whether keeping blood pressure at 85 mmHg or higher during surgery can reduce confusion (delirium) after surgery. It is for older adults with high blood pressure who are having non-cardiac surgery.
HamburgAges 65 years+ - NCT05882370RecruitingPhase 2
Immunotherapy plus TIPS for liver cancer with blocked portal vein
This study tests whether adding the immunotherapy drug cadonilimab (and a related treatment plan) plus TIPS can help people with advanced liver cancer that has a tumor clot causing portal vein pressure problems. It aims to improve disease control while managing the circulation pressure in the liver.
Guangzhou, GuangdongAges 18–75 - NCT06646601Recruiting
Garden-based program for heart and stroke recovery
This trial tests a preventive program that uses a therapeutic garden to help people with heart or blood vessel conditions. It looks at whether patients find the program helpful and easy to take part in.
GapAges 18 years+ - NCT06646198RecruitingPhase 2
TIPS with half-dose Donafenib for liver cancer with portal hypertension
This trial tests a treatment that combines a procedure called TIPS with a targeted therapy drug (Donafenib) at half strength. It is for people with advanced liver cancer that has spread into the portal vein and caused high blood pressure in the liver (portal hypertension). The goal is to see if this combination can help control the cancer and reduce complications.
Guangzhou, GuangdongAges 18–75 - NCT07688928Recruiting
Finerenone vs spironolactone for high blood pressure from aldosteronism
This trial compares two medicines, finerenone and spironolactone, to see which works better and is safer for lowering blood pressure in people with primary aldosteronism. It may help you if you have high blood pressure caused by too much aldosterone.
DhakaAges 18 years+ - NCT07691541Recruiting
Blood pressure monitoring app for pregnancy and after birth
This trial is testing a program that uses a smartphone app to help monitor your blood pressure during pregnancy and after birth. If you're already receiving care at an Ochsner clinic, this study could provide extra support to keep you and your baby healthy.
New Orleans, LouisianaAges 18–80 - NCT07693699Recruiting
Helping with home blood pressure monitoring in primary care
This study provides support for getting and using a home blood pressure monitor if you have high blood pressure. It tests a training pathway to help you track your blood pressure at home.
Chicago, IllinoisAges 18 years+ - NCT07683585Recruiting
Comparing blood pressure drugs after heart stent placement
This trial compares two different combinations of blood pressure medicines to see which works better for people who have had a heart stent placed. It may help find the best treatment plan for controlling blood pressure after the procedure.
MoscowAges 50–70 - NCT07687745RecruitingEarly Phase 1
Breathing exercises for healthy blood pressure during pregnancy
This trial tests whether a simple breathing exercise device can help keep your blood pressure healthy during pregnancy. You will use a small device 5-7 days a week and sync measurements with your smartphone.
Tucson, ArizonaAges 18–55 - NCT07682948RecruitingPhase 1
Drug interaction study of UIC202601 and UIC202602 in healthy volunteers
This trial tests how two experimental drugs, UIC202601 and UIC202602, interact with each other in the body. Healthy volunteers take both drugs to check for side effects and how the body processes them.
Anyang, Manan-guAges 19–54 - NCT07679828Recruiting
Polypill for multiple heart and diabetes risk factors
This study tests a single daily pill combining several medicines to lower blood pressure and cholesterol in people with type 2 diabetes. Taking one pill may be easier than taking multiple medicines, which could help you stay healthy.
Zhengzhou, HenanAges 50–75 - NCT07666841Recruiting
Home-based pulmonary rehab for chronic lung disease
This study tests whether a home-based pulmonary rehabilitation program using a smartphone or computer works as well as in-person rehab for people with chronic lung diseases like COPD or lung scarring. It aims to help you breathe better and feel stronger from home.
AshkelonAges 18 years+ - NCT07665034Recruiting
Isometric exercise for high blood pressure and artery health
This study tests whether a specific type of exercise (isometric exercise) can help slow down the buildup of plaque in arteries (atherosclerosis) in people with high blood pressure. Participants will do the exercise while keeping their blood pressure medication the same, and will be checked with ultrasound and blood pressure monitoring over about 6 months to a year.
ShatinAges 18–80 - NCT03409263Recruiting
Registry for people with TIPS for high portal pressure
This study is a registry, meaning it collects health information to better understand people who have a TIPS procedure for high pressure in the liver’s blood vessels. It may help doctors improve how TIPS is used and monitored over time.
Vienna, State of ViennaAges 18–99 - NCT07648498Recruiting
Handgrip exercise for blood pressure and brain health in older adults
This study tests a simple handgrip exercise program (squeezing a device) done in the community to see if it can help lower blood pressure and improve thinking/memory in older adults. It is open only to people already at the Physical Activity Centre of Excellence at McMaster University.
Hamilton, OntarioAges 65 years+ - NCT06544148Recruiting
Measuring lung artery pressure with a chest belt in ICU patients
This study tests a new way to measure blood pressure in your lung artery using a special belt that sends small electrical signals through your chest. It may help doctors monitor your heart and lungs without extra invasive procedures.
BernAges 18 years+ - NCT06691555Recruiting
Long-term safety of a silicone tube eye implant
This study follows up with people who have previously received a special silicone tube implant in their eye to see how they are doing over time. It aims to check the long-term safety and how well the implant is working.
TbilisiAges 40–90 - NCT07633145Recruiting
Lifestyle Changes to Lower Blood Pressure in Kidney Disease
This study tests whether lifestyle changes—like diet and exercise—can help lower blood pressure in Black adults with moderate kidney disease. It's designed specifically for people at higher risk of kidney problems, and the goal is to see if these changes can slow kidney disease progression and reduce heart disease risk.
Durham, North CarolinaAges 18 years+ - NCT07623525RecruitingPhase 1/Phase 2
DIAG723 study for hereditary hemorrhagic telangiectasia
This study tests a new drug called DIAG723 in adults with hereditary hemorrhagic telangiectasia (HHT), a genetic condition that causes abnormal blood vessels and bleeding. Depending on which part of the study you qualify for, the drug may help reduce nosebleeds, improve anemia, or help with lung blood vessel problems caused by HHT.
Camperdown, New South WalesAges 18 years+ - NCT07628283Recruiting
Telemedicine stroke prevention program for rural elderly adults
This study tests whether using telemedicine (remote health technology) combined with care at a local village clinic can better prevent strokes and manage stroke risk in older adults living in rural areas. Participants will receive ongoing health monitoring and support tailored to their stroke risk factors.
Suqian, JiangsuAges 65 years+ - NCT07626879Recruiting
Ring Blood Pressure Device Compared to Standard 24-Hour Monitoring
This study tests whether a new ring-shaped blood pressure device works as well as the standard 24-hour ambulatory blood pressure monitor in people with heart failure. If the ring device is accurate, it could offer a simpler, more convenient way to track blood pressure at home.
DaeguAges 19 years+
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Common questions
- Are there clinical trials for high blood pressure?
- Yes. Clin2 currently lists 980 recruiting high blood pressure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a high blood pressure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.