Clinical trials
Immunity clinical trials
Below are recruiting immunity clinical trials, each written for real people, not researchers. We’re tracking 973 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06828458Recruiting
Immune response to fungus in burn patients
This study looks at how the immune system fights fungus after a burn. It may help doctors understand which patients are at higher risk for infection and how to better protect them.
ParisAges 18 years+ - NCT06833957Recruiting
Preparing for a maternal GBS vaccine in Africa
This study is preparing for future trials of a vaccine for Group B Strep (GBS) in pregnant women. It includes different parts: watching pregnant women and their babies, surveying GBS infections, and understanding how communities feel about vaccines.
Mariakani, CoastAges Any age - NCT05455034RecruitingPhase 1/Phase 2
Blood and lung-sample test to guide treatment for lung inflammation
This Phase 1/2 study uses detailed “single-cell” testing (from lung samples) to better understand why lung inflammation happens after cancer radiation or immunotherapy. It aims to help choose the right treatment approach for people with radiation pneumonitis or immune checkpoint inhibitor pneumonitis.
Chongqing, Chongqing MunicipalityAges 18–80 - NCT05754203Recruiting
Radiation plus immunotherapy for advanced lung cancer
This trial studies whether a more intensive form of targeted radiation, combined with immunotherapy (immune checkpoint inhibitors), can work better and be safe for people with advanced non-small cell lung cancer. You may be considered if your tumor is limited in size and you’re able to receive both treatments.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT06821100RecruitingPhase 1
Thymalfasin to Boost COVID-19 Vaccine Response in Older Adults
This trial tests whether a drug called thymalfasin (thymosin alpha 1) can help older adults (65+) get a stronger immune response from their COVID-19 booster shot. It may be especially helpful for those whose immune systems have weakened with age.
Houston, TexasAges 65–100 - NCT05152238Recruiting
ITP registry and optional blood sample collection study
This study helps doctors better understand immune thrombocytopenia (ITP) by collecting basic patient information and, if you agree, storing blood samples. It may help future care decisions and research for people with ITP.
AachenAges 18 years+ - NCT06209736RecruitingPhase 2
Study of OMS906 for C3G and ICGN kidney diseases
This study tests an experimental drug called OMS906 for people with C3G or ICGN (immune-related kidney diseases). It aims to see if the drug is safe and can reduce kidney damage. You may qualify if you have a confirmed diagnosis, high protein in your urine, and stable kidney function.
KaunasAges 18–99 - NCT06804135Recruiting
Immune response study during pelvic radiation for cervical cancer
This trial studies how the immune system responds to pelvic radiation therapy (with or without chemotherapy) in patients with cervical or other gynecologic cancers. It may help explain why some treatments work better and could lead to better treatments in the future.
Mumbai, MaharashtraAges 18 years+ - NCT06806137RecruitingPhase 3
Chickenpox vaccine study for healthy toddlers
This study tests how well a second dose of an investigational chickenpox vaccine works and how safe it is in healthy children. Your child would get the first dose between 12-15 months old, then a booster 3 months later.
Salvaleón de Higüey, La Altagracia ProvinceAges 1 year–1.3 years - NCT06809868Recruiting
Study of genetic elements in sepsis and aging
This trial looks at how certain genetic elements may affect the immune system in older adults with sepsis. It aims to understand why older patients may respond differently to severe infections.
San Francisco, CaliforniaAges 18 years+ - NCT06815029RecruitingPhase 1
Modified immune cells for recurrent brain cancer
This trial tests a new treatment using your own immune cells that are genetically modified to find and attack brain tumor cells. It is for people with a type of brain cancer that has come back after standard therapy.
Duarte, CaliforniaAges 18 years+ - NCT06810934RecruitingPhase 1/Phase 2
New COVID-19 vaccine study for those with prior mRNA vaccines
This study tests a new type of COVID-19 vaccine that is designed to train your immune system to make stronger, longer-lasting protection. You may be able to join if you are 40–64, have already had at least two doses of a mRNA COVID-19 vaccine (Pfizer or Moderna) more than 4 months ago, and are generally healthy.
Los Angeles, CaliforniaAges 40–64 - NCT06807593RecruitingPhase 2
Treating ICI-related diarrhea or colitis with ustekinumab
This trial tests if ustekinumab can help cancer patients who have diarrhea or colitis caused by immune checkpoint inhibitors. It may be an option if standard treatments haven't worked or aren't suitable.
Houston, TexasAges 18 years+ - NCT06772623RecruitingPhase 1/Phase 2
Study of telisotuzumab adizutecan plus immunotherapy for advanced lung cancer
This trial tests a new combination treatment for people with advanced non-squamous non-small cell lung cancer who haven't received prior therapy for advanced disease and don't have specific gene changes. The treatment includes an antibody-drug conjugate (telisotuzumab adizutecan) plus an immunotherapy drug (PD-1 checkpoint inhibitor) to see if it helps shrink tumors and improve outcomes.
Phoenix, ArizonaAges 18 years+ - NCT06774235RecruitingPhase 3
Interferon gamma to prevent infections in ICU patients
This trial tests if a drug called interferon gamma can help prevent new infections in ICU patients with a weakened immune system. It may help people who have been in the ICU for at least a week and have had multiple organ failure.
AngersAges 18 years+ - NCT06249438RecruitingPhase 1
CAR-T cell therapy for hard-to-treat autoimmune diseases
This trial tests a new CAR-T cell therapy (C-CAR168) for people with several autoimmune diseases that have not responded to standard treatments. It aims to see if this therapy can control the disease when other medicines have failed.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06762002Recruiting
Immune system study for people with certain immune weaknesses
This study is for adults whose immune system has trouble fighting viruses due to specific antibodies or a genetic condition. Researchers want to follow these people over time to better understand the condition and improve care.
LilleAges 18 years+ - NCT06759064RecruitingPhase 1/Phase 2
Intraperitoneal Immunotherapy and Bone Drug for Stomach Cancer Belly Fluid
This trial tests a combination of two drugs—one that helps your immune system fight cancer (immune checkpoint inhibitor) and one that strengthens bones (zoledronic acid)—given directly into the belly (intraperitoneal) to control fluid buildup caused by stomach cancer. It may help people with moderate to severe malignant ascites who have not had local belly treatments or immunotherapy recently.
Jinan, ShandongAges 18–75 - NCT06760208Recruiting
Learning about Prevenar 20 in the real world in Korea
This study is for people who are already getting the Prevenar 20 vaccine (a shot that protects against pneumonia and other infections) as part of their regular care. The researchers want to see how well it works in the real world, so it's a simple way to help improve vaccines for everyone.
SeoulAges 1 month+ - NCT06740630RecruitingPhase 3
A chickenpox vaccine study for healthy toddlers 12 to 15 months old
This study tests an experimental chickenpox vaccine to see how well it works and if it's safe. Your child may be able to join if they are healthy and between 12 and 15 months old.
Mobile, AlabamaAges 1 year–1.3 years - NCT05859490RecruitingPhase 1/Phase 2
Yellow fever vaccine study for adults with past vaccination
This trial studies how well the yellow fever vaccine “17D” stimulates the immune system (the body’s germ-fighting response) in adults who were vaccinated with 17D years ago. It may help researchers understand whether a prior vaccination still provides protection and how strong the immune response is.
Portland, OregonAges 20–49 - NCT06746077Enrolling by invitation
Lung disease study in children: new ways to understand infections
This study explores how the immune system and lung microbes affect children with lung disease. It uses extra fluid collected during a standard lung exam to look for new treatment targets.
Aarhus NAges birth–17 years - NCT04208828Recruiting
IVIG for difficult gastrointestinal auto-immune nerve symptoms
This trial tests intravenous immunoglobulin (IVIG), a donated antibody treatment, for people whose gastrointestinal (GI) “motor” symptoms are not improving with standard care and may be auto-immune related. If you’re eligible, IVIG could help calm the immune system and improve gut movement symptoms.
Louisville, KentuckyAges 12–90 - NCT06733935RecruitingPhase 1/Phase 2
Study of NKX019 for immune diseases
This trial tests an investigational cell therapy called NKX019 for people with certain autoimmune diseases like scleroderma, myositis, vasculitis, or rheumatoid arthritis. It aims to see if NKX019 can help control the disease when standard treatments have not worked well enough.
Orange, CaliforniaAges 18–75
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Common questions
- Are there clinical trials for immunity?
- Yes. Clin2 currently lists 973 recruiting immunity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a immunity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a immunity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.