Clinical trials
Insulin Sensitivity clinical trials
Below are recruiting insulin sensitivity clinical trials, each written for real people, not researchers. We’re tracking 50 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07186660RecruitingPhase 2
Studying a new insulin sensitizer for type 1 diabetes
This trial tests an oral medication that may help your body respond better to insulin. It's for people with type 1 diabetes who use an automated insulin pump and are willing to take a daily pill for 12 weeks.
Charlottesville, VirginiaAges 18–45 - NCT03883412RecruitingPhase 4
Exercise and liraglutide for type 2 diabetes
This study tests if combining exercise with a drug called liraglutide improves blood vessel health and insulin sensitivity in people with type 2 diabetes. It looks at whether these treatments work better together or alone.
Charlottesville, VirginiaAges 21–60 - NCT05831709Recruiting
Hormone therapy and supervised exercise in menopausal women
This study looks at how hormone replacement therapy and a supervised exercise program may change body composition, heart health risk, and insulin sensitivity in postmenopausal women. It may help participants understand which combination works best for metabolic and cardiovascular health after menopause.
GhentAges 45–65 - NCT07177781Recruiting
Blueberries and brain function in older adults
This study tests whether eating wild blueberries every day for several weeks can improve brain function in people ages 60 to 75 who are overweight or obese. You'll eat blueberry powder or a placebo and have memory and thinking tests before and after.
Maastricht, LimburgAges 60–75 - NCT07057245Recruiting
Protein supplement and brain function in older adults
This study tests whether taking a daily protein supplement can improve how your brain works. It is for healthy older adults (ages 60–75) who are overweight but do not have diabetes or take certain medications.
Maastricht, LimburgAges 60–75 - NCT05943626Recruiting
Sleep timing changes to improve heart and blood sugar health
This study tests whether changing your sleep habits can improve heart-related health and blood sugar control. You may be asked to follow a sleep schedule and other routines, and outcomes will be measured over time.
Salt Lake City, UtahAges 18–45 - NCT06180837Recruiting
Can longer sleep improve heart health in overweight adults?
This study tests if getting more sleep (7+ hours) can lower certain fats in the blood called ceramides, which are linked to heart disease risk. It's for overweight adults who currently sleep less than 6.5 hours a night.
Salt Lake City, UtahAges 18–45 - NCT07422220Recruiting
Walnuts and brain health: a long-term study
This study tests whether eating walnuts every day for a long time can help keep your brain healthy as you age. It is for middle-aged and older adults who carry extra weight around their belly but are otherwise generally healthy.
Maastricht, LimburgAges 45–75 - NCT07465224RecruitingPhase 2
Study of ALN-4324 on Insulin Sensitivity in Type 2 Diabetes
This study tests an experimental drug, ALN-4324, to see if it can improve how your body responds to insulin. It’s for adults with type 2 diabetes who are already on certain diabetes medications and have stable blood sugar control.
Chula Vista, CaliforniaAges 18–65 - NCT04596592Recruiting
Puberty blockers and estradiol effects on heart health
This study looks at how puberty blockers and then estradiol (estrogen) may affect heart and metabolism health in teens. It may help doctors understand risks and benefits for transgender youth starting gender-affirming hormone care.
Aurora, ColoradoAges 13–16 - NCT07699380RecruitingPhase 2
Metabolic study to improve insulin sensitivity in type 1 diabetes
This study tests a new medication to see if it can improve how your body responds to insulin and boost your cells' energy (mitochondrial function). It is for adults with type 1 diabetes who are already on insulin and have good overall health.
Seattle, WashingtonAges 18–69 - NCT04966351Recruiting
Study countermeasures for disrupted body clock timing
This study tests ways to help your body’s internal clock stay in sync when your sleep timing is off. It’s looking for healthy adults with fairly regular sleep and certain lifestyle and location history.
Fort Collins, ColoradoAges 18–35 - NCT05337098Recruiting
Sweetener study in older adults with prediabetes
This study tests whether eating non-nutritive sweeteners changes how your body handles sugar (glucose control). It may help researchers learn if sweeteners are helpful or harmful for people with prediabetes.
Blacksburg, VirginiaAges 40 years+ - NCT05383092Recruiting
Exercise program for kids with cancer and healthy insulin
This trial studies an adapted exercise (physical activity) program for children starting treatment for cancer to see if it can improve insulin sensitivity. It may help kids feel better and support healthy body metabolism during treatment.
ToulouseAges 5–18 - NCT05933499RecruitingPhase 2
Tirzepatide and bimagrumab for body fat and insulin sensitivity
This Phase 2 study tests two medicines to see how they change body fat, insulin sensitivity, and bone health in adults with obesity. It may help people who have tried lifestyle changes to lose weight but have not been able to, though diabetes and several health conditions must be ruled out first.
Boston, MassachusettsAges 18 years+ - NCT05987631Recruiting
Predicting weight loss and health after weight loss surgery
This study looks at why some people lose more weight and improve their health more than others after bariatric surgery. It also has a subgroup that specifically studies people who are insulin resistant (a sign of prediabetes) to see how surgery affects their metabolism.
Gouda, South HollandAges 18–75 - NCT05992688Recruiting
Sweet Kids Study: Stevia and Weight Over Time
This study tests whether replacing sugary drinks with stevia-sweetened drinks over time can help children manage their weight. Your child would drink the study beverages instead of their usual sugary drinks and have weight and health checks.
Little Rock, ArkansasAges 8–12 - NCT06042517Recruiting
Ultrasound Nerve Stimulation for Diabetes
This study tests whether focused ultrasound can help people with type 2 diabetes by gently stimulating nerves. It may offer a new way to improve glucose control without medication.
New Haven, ConnecticutAges 18–80 - NCT06282055Recruiting
Insulin sensitivity changes during menstrual cycles in type 1 diabetes
This study looks at how insulin sensitivity changes during the menstrual cycle in women with type 1 diabetes. It may help find patterns that could improve diabetes care.
BernAges 18–40 - NCT06359444Recruiting
Exercise therapy for fatty liver disease
This study tests whether a high-intensity exercise program can improve liver function and insulin sensitivity in people with MASLD (a type of fatty liver disease). It may help you if you are looking for a non-drug way to manage your condition.
GhentAges 18–75 - NCT06878781Recruiting
How your body processes food after a meal
This study looks at how young, healthy adults break down food after eating. It uses blood tests and a metabolic challenge to measure energy use and chemical changes.
Mexico CityAges 18–30 - NCT07198100Recruiting
Ear stimulation, motivation, and insulin sensitivity in depression
This study explores how a gentle electrical stimulation of the ear might affect mood, motivation, and insulin sensitivity in people with and without depression. It aims to see if this non-invasive technique could offer new ways to help with depression.
BonnAges 18–60 - NCT07271771RecruitingPhase 4
Denosumab for muscle and insulin in diabetes
This study tests whether denosumab, a medication that strengthens bones, can also improve muscle strength and insulin sensitivity in postmenopausal women with type 2 diabetes who take metformin.
AarhusAges 40 years+ - NCT01477957Recruiting
Bariatric surgery and changes in insulin and body energy use
This study tests whether weight-loss surgery improves how your body uses insulin and energy. It compares insulin sensitivity and related measurements before and after surgery to understand who benefits.
Düsseldorf, North Rhine-WestphaliaAges 20–70
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Common questions
- Are there clinical trials for insulin sensitivity?
- Yes. Clin2 currently lists 50 recruiting insulin sensitivity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a insulin sensitivity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a insulin sensitivity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.