Clinical trials
Insulin clinical trials
Below are recruiting insulin clinical trials, each written for real people, not researchers. We’re tracking 352 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05206877RecruitingPhase 1
Topical insulin eyedrops for glaucoma-related eye nerve damage
This Phase 1 study tests an insulin-based eye treatment to see if it’s safe and potentially helpful for people with glaucoma-related optic nerve damage. If you may be eligible, you’ll have a close eye exam and repeated vision testing, mainly focused on one study eye.
Palo Alto, CaliforniaAges 18 years+ - NCT07076199RecruitingPhase 3
Weekly vs daily insulin for type 1 diabetes
This study tests a new once-weekly insulin (icodec) against a standard daily insulin (glargine), both taken with mealtime insulin. It aims to see which works better to control blood sugar in adults with type 1 diabetes.
Cullman, AlabamaAges 18 years+ - NCT07112339RecruitingPhase 4
Weekly insulin vs daily insulins for type 2 diabetes
This study tests a new once-weekly insulin shot (icodec) compared to daily long-acting insulins for people with type 2 diabetes whose blood sugar is not well controlled on their current non-insulin medications.
Calgary, AlbertaAges 18 years+ - NCT03463564RecruitingPhase 4
Insulin pump versus insulin shots for type 1 diabetes control
This study compares an insulin pump to insulin shots to see which better improves blood sugar control and reduces swings in people with type 1 diabetes. You may be included if your diabetes is not well controlled despite education and you’ve had low blood sugar episodes.
NaplesAges 18–30 - NCT06216665Recruiting
Pulse hormone effects on insulin
This trial is only for people who completed a previous study called Motivate and had their final insulin test. It tests how giving hormones in pulses affects how your body uses insulin.
Baton Rouge, LouisianaAges 50–75 - NCT06280703RecruitingPhase 1
Study of LY3938577 for type 1 diabetes
This study tests an investigational drug called LY3938577 in healthy people and people with type 1 diabetes. It looks at how the drug affects the body and whether it might help control blood sugar.
NeussAges 18–64 - NCT06592261RecruitingPhase 1
Insulin suppression test for weight groups
This study tests a new way to measure how the body handles insulin in people with different body weights. It may help researchers understand insulin resistance better.
New York, New YorkAges 18–65 - NCT06966427Recruiting
Using a dosing app for insulin management
This trial studies a smartphone system that helps people with diabetes decide how much insulin to take. It is for people who use insulin injections or are starting basal insulin, and it uses a continuous glucose monitor to guide dosing.
Petah TikvaAges 6–75 - NCT07171684Recruiting
Insulin Dosing for Blood Sugar Control in Pregnancy
This study compares giving one daily dose of insulin versus multiple doses to see which works better for controlling blood sugar in pregnant women with diabetes. It might help you if you need insulin during pregnancy and want to find a simpler treatment plan.
New Brunswick, New JerseyAges 18–50 - NCT07265323Recruiting
Testing insulin effects on brain function
This study looks at how giving insulin in a way that mimics the body's natural release can affect thinking and memory. It may help understand how insulin relates to brain health.
Baton Rouge, LouisianaAges 18 years+ - NCT07516509Recruiting
How muscle cells respond to blood sugar in different body types
This research study examines how muscle cells handle blood sugar differently depending on whether someone is lean or has obesity, and whether their body resists insulin. Researchers will take small muscle samples to understand the genetic differences, which may help develop better treatments for insulin resistance and metabolic health.
Orlando, FloridaAges 30–65 - NCT03932162RecruitingEarly Phase 1
Skin study that checks gene changes in young and older adults
This early-stage study looks at how your skin’s genes respond after a controlled skin procedure. It may help researchers understand differences in skin biology between younger and older adults.
Fairborn, OhioAges 21 years+ - NCT07109245RecruitingPhase 4
Do antipsychotics block insulin action in the brain?
This study tests whether a single dose of a common antipsychotic medication affects how the brain responds to insulin, which could help explain weight gain and metabolic side effects. Healthy young adults will receive either the antipsychotic or a placebo, then have their brain activity measured with an MRI.
Toronto, OntarioAges 18–35 - NCT07224893RecruitingPhase 4
Once vs Twice Daily Insulin in Pregnant Diabetes
This trial compares taking insulin glargine once a day versus twice a day for pregnant women with type 2 diabetes. It aims to find which schedule helps manage blood sugar better during pregnancy.
Norfolk, VirginiaAges 18 years+ - NCT07746206RecruitingEarly Phase 1
Insulin vs hyaluronic acid gel for advanced gum disease
This study compares two treatments applied directly to the gums to see which one better helps severe gum disease (periodontitis) heal. If you have advanced gum disease and haven't had treatment recently, you may be able to join.
CairoAges Any age - NCT06925334Enrolling by invitationPhase 4
Comparing a new insulin combo with premixed insulin for type 2 diabetes
This study tests whether a new injection that combines insulin with liraglutide works better than standard premixed insulin for people with type 2 diabetes. It aims to improve blood sugar control and simplify treatment.
Beijing, Beijing MunicipalityAges 18–75 - NCT07732777Recruiting
AI-assisted insulin pump study for type 1 diabetes
This study tests whether an artificial intelligence (AI) system can help manage insulin pump therapy remotely for people with type 1 diabetes. The goal is to improve blood sugar control and make diabetes management easier.
Nanjing, JiangsuAges 14–65 - NCT06880835Recruiting
Inhaled insulin vs injected insulin for exercise blood sugar drops in type 1 diabetes
This trial tests whether a new inhaled insulin (Technosphere) causes fewer low blood sugar episodes during exercise compared to standard injected insulin in people with type 1 diabetes who use an automated insulin pump. It may help you avoid hypoglycemia while staying active.
Louisville, KentuckyAges 18–65 - NCT04883515Recruiting
Glutamine drink for insulin resistance and bowel symptoms
This trial studies whether taking an oral glutamine supplement can improve insulin resistance and reduce bowel-related problems in people with obesity and irritable bowel syndrome. It may help your blood sugar regulation and digestive comfort if you meet the criteria.
RouenAges 18–65 - NCT06883344Recruiting
Automated insulin for managing blood sugar during labor
This study tests if an automated insulin delivery system can help manage blood sugar levels during labor and delivery in pregnant women with type 1 diabetes. If successful, it could make the process safer and easier.
Los Angeles, CaliforniaAges 18–55 - NCT05010356Recruiting
Testing insulin sensitivity after breast cancer treatment
This study looks at how well your body uses insulin (a hormone that helps move sugar from the blood into cells) after breast cancer treatment. It may help researchers understand whether insulin sensitivity changes after chemotherapy and could guide future health monitoring.
Copenhagen, DKAges 20–45 - NCT05065372RecruitingPhase 1
Metformin test with automated insulin in teens with type 1
This Phase 1 study tests how adding metformin affects blood flow in the kidneys, insulin sensitivity, and overall heart/metabolic health in young people with type 1 diabetes. It may help researchers understand whether this combo is safe and beneficial alongside automated or pump/shot insulin care.
Aurora, ColoradoAges 12–25 - NCT05233722Recruiting
Study of how mTOR affects insulin sensitivity in healthy men
This study looks at whether a body pathway called mTOR helps control how your body handles insulin and blood sugar. It’s done in healthy men to understand insulin sensitivity before testing approaches in people with health problems later.
CopenhagenAges 22–35 - NCT05833217Recruiting
Study for persistent COVID symptoms with insulin resistance
This trial studies people who have ongoing effects after COVID (often called PASC) and may be related to weight and insulin resistance. It may help researchers find better ways to understand the condition and improve treatment.
Palo Alto, CaliforniaAges 18–80
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Common questions
- Are there clinical trials for insulin?
- Yes. Clin2 currently lists 352 recruiting insulin studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a insulin trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a insulin trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.