Clinical trials
Insulin clinical trials
Below are recruiting insulin clinical trials, each written for real people, not researchers. We’re tracking 344 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06781775RecruitingPhase 4
Metformin vs insulin for gestational diabetes
This trial compares two medicines—metformin pills and insulin shots—to see which works better for controlling blood sugar in gestational diabetes. You may be able to join if you have gestational diabetes that needs treatment and are willing to take either medicine.
Charlottesville, VirginiaAges 18–50 - NCT03932162RecruitingEarly Phase 1
Skin study that checks gene changes in young and older adults
This early-stage study looks at how your skin’s genes respond after a controlled skin procedure. It may help researchers understand differences in skin biology between younger and older adults.
Fairborn, OhioAges 21 years+ - NCT07403604RecruitingPhase 1
Lowering Insulin to Reduce Fat Buildup in the Liver
This study tests if lowering insulin levels can reduce fat buildup in the liver for people with a fatty liver condition called MASLD. It's looking for adults who are overweight and have early signs of insulin resistance but not diabetes.
New York, New YorkAges 18–65 - NCT07348432Recruiting
Insulin delivery and eating behaviors in type 1 diabetes
This study looks at how different insulin delivery methods (like injections or pumps) affect eating behaviors in people with type 1 diabetes. By joining, you may help researchers learn how to improve care and quality of life.
Montreal, QuebecAges 12 years+ - NCT07341373RecruitingPhase 1
Testing a new insulin delivery method for type 1 diabetes
This study tests a new way to give insulin directly into the abdomen (intraperitoneal) for people with type 1 diabetes. It will check how safe and effective a single dose is over 12 hours, using a special procedure to keep blood sugar stable (clamp).
Chula Vista, CaliforniaAges 18–60 - NCT07307235RecruitingPhase 4
Comparing a new diabetes combination to standard care for type 2 diabetes
This trial tests if a once-daily injectable combination (iGlarLixi) helps control blood sugar better than usual care for people with type 2 diabetes who are already taking diabetes pills. It aims to find a more effective treatment option.
Hefei, AnhuiAges 18 years+ - NCT06487832Recruiting
Effect of diabetes drug on brain response to insulin
This study tests whether a GLP-1 receptor agonist (a type of diabetes medicine) changes how the brain responds to insulin in people with different body sizes. It may help understand if this drug can improve brain function related to insulin.
TübingenAges 18–70 - NCT07240012Recruiting
Automated insulin delivery before and during pregnancy for type 1 diabetes
This trial tests whether an automated insulin delivery system can improve blood sugar control compared to usual insulin methods before and during pregnancy in women with type 1 diabetes.
Aalborg, AalborgAges 18–45 - NCT07224893RecruitingPhase 4
Once vs Twice Daily Insulin in Pregnant Diabetes
This trial compares taking insulin glargine once a day versus twice a day for pregnant women with type 2 diabetes. It aims to find which schedule helps manage blood sugar better during pregnancy.
Norfolk, VirginiaAges 18 years+ - NCT07220694Recruiting
Sabroxy supplement for memory and insulin resistance
This study tests whether a supplement called Sabroxy can improve insulin resistance and memory in adults with mild cognitive impairment and insulin resistance. It may help if you have early memory problems and your blood sugar is slightly higher than normal.
San Francisco, CaliforniaAges 40–80 - NCT07109245RecruitingPhase 4
Do antipsychotics block insulin action in the brain?
This study tests whether a single dose of a common antipsychotic medication affects how the brain responds to insulin, which could help explain weight gain and metabolic side effects. Healthy young adults will receive either the antipsychotic or a placebo, then have their brain activity measured with an MRI.
Toronto, OntarioAges 18–35 - NCT07011147Recruiting
Real-world test of automated insulin delivery in primary care
This study tests if an automated insulin delivery system (the iLet bionic pancreas) works well in real-world primary care settings for people with type 1 or type 2 diabetes. It aims to see if this technology can help manage blood sugar more easily.
Aurora, ColoradoAges 18–89 - NCT05065372RecruitingPhase 1
Metformin test with automated insulin in teens with type 1
This Phase 1 study tests how adding metformin affects blood flow in the kidneys, insulin sensitivity, and overall heart/metabolic health in young people with type 1 diabetes. It may help researchers understand whether this combo is safe and beneficial alongside automated or pump/shot insulin care.
Aurora, ColoradoAges 12–25 - NCT06925334Enrolling by invitationPhase 4
Comparing a new insulin combo with premixed insulin for type 2 diabetes
This study tests whether a new injection that combines insulin with liraglutide works better than standard premixed insulin for people with type 2 diabetes. It aims to improve blood sugar control and simplify treatment.
Beijing, Beijing MunicipalityAges 18–75 - NCT06918977Recruiting
Telemedicine and smart insulin pens for diabetes
This trial is testing whether a telemedicine program combined with smart insulin pens can help improve blood sugar control. It is for people with diabetes who use multiple daily insulin injections and have a smartphone.
Baltimore, MarylandAges 18 years+ - NCT06883344Recruiting
Automated insulin for managing blood sugar during labor
This study tests if an automated insulin delivery system can help manage blood sugar levels during labor and delivery in pregnant women with type 1 diabetes. If successful, it could make the process safer and easier.
Los Angeles, CaliforniaAges 18–55 - NCT06880835Recruiting
Inhaled insulin vs injected insulin for exercise blood sugar drops in type 1 diabetes
This trial tests whether a new inhaled insulin (Technosphere) causes fewer low blood sugar episodes during exercise compared to standard injected insulin in people with type 1 diabetes who use an automated insulin pump. It may help you avoid hypoglycemia while staying active.
Louisville, KentuckyAges 18–65 - NCT06776094Recruiting
Exercise and insulin sensitivity study in healthy men
This trial looks at how physical activity affects how your body responds to insulin in healthy men aged 22-35. If you are a non-smoking man with a BMI between 28 and 35 and a certain fitness level, you may be eligible.
CopenhagenAges 22–35 - NCT06138821Recruiting
Endoscopic sleeve gastroplasty for obesity and MASH
This study tests if a procedure called endoscopic sleeve gastroplasty helps people with obesity and a liver condition called MASH lose weight and improve their liver health. It might be an option if you have both obesity and MASH and haven't had weight-loss surgery before.
Boston, MassachusettsAges 18 years+ - NCT05988632RecruitingPhase 1/Phase 2
Insulin nasal spray for alcohol use disorder
This trial tests whether a nasal spray with insulin can help people with alcohol use disorder. It may affect how the brain responds to alcohol and reduce drinking.
Providence, Rhode IslandAges 21 years+ - NCT04883515Recruiting
Glutamine drink for insulin resistance and bowel symptoms
This trial studies whether taking an oral glutamine supplement can improve insulin resistance and reduce bowel-related problems in people with obesity and irritable bowel syndrome. It may help your blood sugar regulation and digestive comfort if you meet the criteria.
RouenAges 18–65 - NCT04708535Enrolling by invitation
Study how fat changes affect insulin resistance after bariatric surgery
This study looks at how your body’s fat under the skin and inside the abdomen may affect “insulin resistance,” a common problem linked with blood sugar control. It’s for people who are scheduled for bariatric (weight-loss) surgery, to learn more before and after surgery.
Stanford, CaliforniaAges 30–65 - NCT05553093RecruitingPhase 4
Tirzepatide vs insulin for diabetes and brain effects
This study tests how tirzepatide and insulin glargine affect blood sugar, fat metabolism, and brain function in adults with type 2 diabetes. It may help researchers learn which treatment changes diabetes-related body and brain processes.
Nanjing, JiangsuAges 18–75 - NCT05124457RecruitingPhase 2
Detemir vs NPH insulin for diabetes in pregnancy
This Phase 2 study compares two types of insulin—insulin detemir vs NPH—to see which works better and is safe for controlling blood sugar during pregnancy. You may be invited if you are pregnant and need insulin for either pre-existing type 2 diabetes or gestational diabetes.
Los Angeles, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for insulin?
- Yes. Clin2 currently lists 344 recruiting insulin studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a insulin trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a insulin trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.