Clinical trials
Intraoperative clinical trials
Below are recruiting intraoperative clinical trials, each written for real people, not researchers. We’re tracking 272 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03745560Recruiting
Test hearing testing during surgery to guide cochlear implant decisions
This study uses a special hearing test done during surgery for vestibular schwannoma to help decide what hearing treatment you need afterward. It may help guide whether a cochlear implant is a good option for hearing rehabilitation.
Vienna, AustriaAges 18–99 - NCT03873259Recruiting
Testing a new way to check kidney stones during surgery
This trial tests a method called burst wave lithotripsy (BWL) to help doctors assess and treat kidney stones during a planned ureteroscopy procedure. It may help surgeons confirm how well the stone is being broken while you are on the operating table.
Carmel, IndianaAges 18 years+ - NCT07702487Recruiting
Warming before kidney surgery study
This trial tests if warming the body before kidney surgery can lower lactate levels, which may help recovery. It is for adults scheduled for a planned (not emergency) kidney removal.
Istanbul, SisliAges 18–90 - NCT04182997RecruitingPhase 4
Epidural steroid shot during discectomy for back nerve pain
This trial studies whether giving a steroid medicine into the epidural space during discectomy (back surgery for a herniated disc) helps reduce nerve pain and symptoms. It is mainly for people whose MRI and exam show a single-level lumbar disc herniation after non-surgical treatments didn’t help.
Columbia, MissouriAges 18 years+ - NCT04209218Recruiting
Blood pressure and dexamethasone during lung cancer surgery
This study looks at how best to manage blood pressure during lung cancer surgery and whether giving dexamethasone (a steroid medicine) helps patients during the operation and recovery. You might benefit if you’re having longer lung cancer surgery and your heart and other organs are stable enough for the study.
Beijing, Beijing MunicipalityAges 50–90 - NCT04518761Recruiting
Predicting breathing relaxation using a nerve monitoring test
This trial is testing a prediction method during surgery to estimate how strongly a medicine is relaxing your breathing muscles, using a nerve monitoring signal. It may help anesthesiology teams adjust anesthesia more safely during general anesthesia for non-heart surgeries.
Jette, Brussels CapitalAges 18 years+ - NCT04603209Recruiting
Check-in registry for radiation during breast-conserving surgery
This registry study tracks people with early-stage, single-area breast cancer to understand outcomes when radiation is given during breast-conserving surgery. It may help doctors improve treatment planning for patients like you.
Santa Monica, CaliforniaAges 18 years+ - NCT04666103Recruiting
Study of neck anatomy in thyroid surgery
This study looks at how the structures in the neck affect thyroid surgery outcomes. You may be asked about your diagnosis and pre-surgery neck imaging to better understand surgical safety for people with certain thyroid conditions.
Wuhan, HubeiAges 18–75 - NCT04723810RecruitingPhase 1/Phase 2
Test a glowing scan to help surgeons find tumor tissue
This early-stage study tests an intraoperative imaging approach called “TumorGlow” to help surgeons better identify tumor tissue during surgery. It may help improve the completeness of tumor removal and reduce the chance of recurrence in certain patients.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04752137RecruitingPhase 2
ICG dye imaging during surgery to check tumor edges
This trial tests whether a special dye (ICG) seen during your surgery can help doctors better identify the edges of a tumor in bone or soft tissue. It may help ensure as much of the tumor is removed as safely as possible.
Boston, MassachusettsAges 18 years+ - NCT04780009Recruiting
Imaging tool during brain tumor surgery
This trial tests a special camera system used during surgery to help doctors see brain tumor tissue using fluorescent light. It may help the surgeon remove more tumor while protecting healthy brain areas.
Lexington, KentuckyAges 18–90 - NCT04811313Recruiting
Tranexamic acid for children having hip bone surgery
This study tests whether tranexamic acid (a medicine that helps reduce bleeding) can safely help children during certain hip bone operations. It may help lower blood loss around the surgery.
AsyutAges 1–18 - NCT04842162RecruitingPhase 2
Near-infrared dye imaging to help remove all mouth/throat cancer
This Phase 2 study tests a special camera and dye during surgery to help surgeons confirm they removed all cancer at the edge of the removed tissue. If it works, it may lower the chance of cancer being left behind after oral cavity or oropharynx squamous cell cancer surgery.
AnderlechtAges 18 years+ - NCT04900298Recruiting
Hand hygiene device study during adult surgeries
This study tests whether a personal hand-hygiene system helps reduce germs spreading during surgery. It involves adults having certain types of surgeries and the anesthesia team caring for them.
Portland, OregonAges 18–99 - NCT07568158Recruiting
How Anesthesia Nurses Handle Multiple Tasks During Surgery
This study looks at how anesthesia nurses manage their workload during different stages of surgery. Researchers will observe and measure how busy nurses feel while they care for patients under anesthesia, which could help improve training and safety in operating rooms.
Barcelona, CataloniaAges 18 years+ - NCT05023434Recruiting
Brain stimulation study for hand strength in brain tumor patients
This study uses brain stimulation during surgery to see how it affects hand strength and hand function. It may help doctors understand which brain areas are important for hand movement in people with certain brain tumors.
Milwaukee, WisconsinAges 18–75 - NCT05150795RecruitingEarly Phase 1
Testing pregabalin before surgery versus fentanyl during surgery
This trial compares two medicines used around the time of surgery—pregabalin given by mouth before surgery versus fentanyl given during surgery—to see which better controls pain after the operation. You might join if you’re a generally healthy surgical patient and aren’t using certain related medicines.
CairoAges 21–45 - NCT05168280Recruiting
Dexmedetomidine during brain surgery to prevent confusion in seniors
This trial tests whether giving a medication called dexmedetomidine during selective brain surgery can help prevent postoperative delirium, a sudden episode of confusion, in older adults. If you qualify, the study team would give the medication during the operation and compare outcomes after surgery.
Beijing, Beijing MunicipalityAges 65 years+ - NCT05196503RecruitingPhase 3
PRF gel in spine surgery to reduce nerve pain after herniation
This Phase 3 study tests whether applying a healing material called platelet-rich fibrin (PRF) around the nerve during disc herniation surgery can reduce leftover nerve pain afterward. If you qualify, your team will compare pain intensity between standard care and PRF during the operation.
Strasbourg, Bas-RhinAges 18 years+ - NCT05356286Recruiting
Recording spinal cord stimulation and monitoring during surgery
This study records what happens when doctors use spinal cord monitoring and stimulation during brain or spinal cord surgery. It may help improve how safely these procedures are performed in the future.
Los Angeles, CaliforniaAges 18 years+ - NCT05445960Recruiting
Tourniquet use during ankle surgery and recovery outcomes
This study looks at whether using a tourniquet during ankle fracture surgery affects healing, leg movement, and patient-reported recovery. It may help doctors choose the safest, most comfortable approach for surgery.
Portland, OregonAges 18–89 - NCT05477680Recruiting
Measuring brain shift during surgery using navigation
This study tests whether a special brain-navigation method can better measure how the brain moves during surgery for certain brain conditions. If it works, it may help surgeons avoid mistakes caused by brain shifting while you are under anesthesia.
MoscowAges 18–100 - NCT05482126Recruiting
Studying brain sensing in advanced Parkinson’s during deep brain stimulation
This study looks at how the brain “filters” sensory information in people with advanced Parkinson’s disease, using brain imaging and deep brain stimulation (DBS) that you may already be getting as routine care. The goal is to better understand what drives Parkinson’s symptoms and how DBS might affect the brain.
Birmingham, AlabamaAges 18–89 - NCT05565118RecruitingPhase 1
Brain activity study during surgery for high-grade glioma
This early-stage study measures electrical brain activity during brain tumor surgery to see if it can predict tumor return or progression. You may be offered the additional measurements while your surgeon removes a suspected or known high-grade glioma.
Cleveland, OhioAges 18 years+
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Common questions
- Are there clinical trials for intraoperative?
- Yes. Clin2 currently lists 272 recruiting intraoperative studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a intraoperative trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a intraoperative trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.