Clinical trials
Kidney Failure, Chronic clinical trials
Below are recruiting kidney failure, chronic clinical trials, each written for real people, not researchers. We’re tracking 229 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04447911RecruitingPhase 4
Empagliflozin for chronic low blood sodium in certain fluid states
This trial studies whether empagliflozin, a blood-sugar–related medicine, can safely improve chronic low blood sodium when you are not too “dry” or have an imbalanced fluid state. It may help stabilize sodium levels and related health symptoms, but you must meet specific blood and organ-function criteria.
WürzburgAges 18 years+ - NCT07760363Recruiting
Foot exercise device for leg swelling
This study tests if using a foot pedal device while lying down can help reduce leg swelling in the hospital. It aims to see if this simple exercise can improve comfort and outcomes for people with fluid buildup.
Tulsa, OklahomaAges 18 years+ - NCT07428395Enrolling by invitation
Monitoring during continuous kidney replacement therapy in the ICU
This study tests a new way to monitor patients while they receive continuous kidney replacement therapy (a type of dialysis) in the ICU. It aims to see if this monitoring can be done safely and smoothly, helping doctors track your treatment better.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06972069RecruitingEarly Phase 1
Building tolerance to a new kidney with Sip-Tego
This study tests a new combination of medicines (Sip-Tego) to help your body accept a living donor kidney without needing lifelong anti-rejection drugs. It is for people with advanced kidney failure who are getting a first or second transplant.
Boston, MassachusettsAges 18–65 - NCT03524222Recruiting
Home hospital care for adults after sudden illness
This trial tests whether certain adults can safely receive hospital-level care at home instead of staying in the hospital, using a home care team. It may help you recover in your own home if your condition fits their plan and you have support at home.
Boston, MassachusettsAges 18 years+ - NCT05279742Enrolling by invitationPhase 1/Phase 2
Study drug to boost a hormone system in HFpEF
This early-phase trial tests a treatment that aims to improve the “natriuretic peptide” hormone system in people with HFpEF (heart failure with preserved pumping strength). It may help reduce symptoms and improve heart and fluid pressure behavior, especially in certain related conditions like kidney disease.
Rochester, MinnesotaAges 18 years+ - NCT07748858Recruiting
Heart care support for older African American patients
This study aims to improve care for older African American patients with heart conditions and other health problems. It tests ways to provide more patient-centered support.
Birmingham, AlabamaAges 50–99 - NCT05966415RecruitingPhase 2
Endocalyx for heart failure with fluid overload
This Phase 2 study tests Endocalyx to treat people with heart failure who currently show signs of fluid buildup (congestion). If you qualify, you may help researchers see whether this supplement can improve symptoms and heart-failure–related measurements.
Amsterdam, North HollandAges 18–110 - NCT06238310Recruiting
Comparing two markers to measure kidney function in intensive care
This trial compares two different substances, mannitol and iohexol, to see which one better measures how well your kidneys are filtering waste. It is for patients in intensive care with sudden or ongoing kidney problems, as well as stable chronic kidney disease patients seen in outpatient clinics.
GothenburgAges 18 years+ - NCT06463483Recruiting
Automated Insulin Delivery for People with Advanced Kidney Disease
This trial tests an automated insulin pump system for people with diabetes who also have advanced kidney disease. It may help manage blood sugar more easily.
LondonAges 18–70 - NCT06560801RecruitingPhase 4
Dapagliflozin for kidney health after transplant
This trial tests whether taking dapagliflozin (a drug often used for diabetes and heart health) can help improve kidney structure and blood flow in people who received a kidney transplant at least 9 months ago. It may benefit those whose kidney function is stable, regardless of whether they have diabetes.
Erlangen, BavariaAges 18–75 - NCT07086989Recruiting
Heart health study for kids with chronic conditions
This study looks at heart disease risk in children and young adults (ages 6-25) with long-term health conditions like certain heart, kidney, or diabetes disorders. The goal is to better understand and manage heart risks early.
BudapestAges 6–25 - NCT05397392Recruiting
Diagnosis and treatment plan for heart–kidney problems
This study looks at the best way to diagnose and treat different types of heart-and-kidney problems that happen together. It may help you (or your caregiver) get the right classification and treatment approach based on how your heart and kidneys are affected.
NanjingAges 18 years+ - NCT06225544RecruitingPhase 2
Lumasiran for high oxalate patients on hemodialysis
This trial tests a drug called Lumasiran to lower oxalate levels in patients on hemodialysis (a type of kidney dialysis). It may help reduce complications from high oxalate, which can damage organs.
BerlinAges 18–80 - NCT06274710Recruiting
Kidney health support trial for those at dialysis risk
This study tests a new care program to help people with chronic kidney disease (CKD) who have a higher risk of needing dialysis soon. It uses online tools to support you and your care team in managing your health.
Toronto, OntarioAges 18 years+ - NCT07358572Recruiting
Eye-brain-kidney study in chronic kidney disease
This study is looking at how chronic kidney disease (CKD) affects the eyes, brain, and kidneys. It uses MRI scans to examine these organs, and aims to find connections that could help improve care for people with CKD.
Beijing, Beijing MunicipalityAges 18–70 - NCT07662889Enrolling by invitation
Comparing two types of dialysis for kidney failure
This trial compares a newer type of dialysis called hemodiafiltration with standard hemodialysis to see if it improves certain health measures in people with end-stage kidney disease. It may help determine which method works better for long-term treatment.
Lahore, Punjab ProvinceAges 18–70 - NCT06542016Recruiting
Heart risk prediction in dialysis patients using a questionnaire
This study looks at how a simple questionnaire (called KCCQ) about your heart health and quality of life can help predict future heart risks for people on dialysis. Researchers want to see if your answers to this questionnaire can help doctors take better care of you.
Guangdong, GuangdongAges 18 years+ - NCT05014178Recruiting
Kidney salt imaging scan with MRI
This study uses an MRI scan to look at how your kidneys handle salt (sodium). It may help researchers better understand kidney function in healthy people and in people with chronic kidney disease.
London, OntarioAges 18 years+ - NCT06082063RecruitingPhase 3
Reducing heart disease risk in type 1 diabetes
This trial tests a combination of treatments to lower the risk of heart disease and kidney problems in people with type 1 diabetes who already have some complications or higher risk. If you qualify, you will receive extra care aimed at preventing heart attacks, strokes, and kidney failure.
CopenhagenAges 40–90 - NCT06858280RecruitingPhase 3
Patiromer and diet for potassium in dialysis patients
This trial tests if a medication called patiromer, combined with a low-potassium diet, can help manage potassium levels in people on chronic dialysis. The goal is to improve quality of life by allowing a more flexible diet.
Bergamo, BGAges 18 years+ - NCT07290842Recruiting
Dietary nitrate for high blood pressure kidney injury
This study tests whether a natural substance found in leafy greens (dietary nitrate) can help protect the kidneys of people with high blood pressure and early kidney damage. It may offer a simple dietary way to slow kidney disease.
HerningAges 18–70 - NCT02947750RecruitingPhase 2
Exercise study in people with kidney disease
This Phase 2 study tests how engaging in supervised exercise affects the body’s blood-vessel responses in people with chronic kidney disease (CKD) who don’t exercise regularly. It may help researchers understand whether exercise could be beneficial for CKD-related health changes.
Atlanta, GeorgiaAges 18–75 - NCT06801886Enrolling by invitationPhase 3
Silymarin for better kidney transplant success
This trial tests if adding silymarin (a milk thistle extract) to standard anti-rejection medicines helps protect the new kidney from damage. It may improve how well the transplanted kidney works over time.
MartinAges Any age
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Common questions
- Are there clinical trials for kidney failure, chronic?
- Yes. Clin2 currently lists 229 recruiting kidney failure, chronic studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a kidney failure, chronic trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a kidney failure, chronic trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.