Clinical trials
Left Main Coronary Artery Stenosis clinical trials
Below are recruiting left main coronary artery stenosis clinical trials, each written for real people, not researchers. We’re tracking 87 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04795193Enrolling by invitation
Minithoracotomy vs open surgery for multiple blocked heart arteries
This trial compares two types of bypass surgery for people with multiple blocked heart arteries, to see which one better improves quality of life and how well the bypasses stay open. You may be assigned based on your preferences, and the study also tracks heart scan and follow-up results.
Beijing, Beijing MunicipalityAges 25–85 - NCT06218485Recruiting
Comparing two methods to guide heart stenting
This study compares two ways to guide stenting for blocked heart arteries: one uses a pressure wire (FFR) to measure blood flow, and the other uses ultrasound (IVUS) plus a computer estimate of blood flow. The goal is to see which approach leads to better outcomes after stent placement.
BeijingAges 19 years+ - NCT07444957Recruiting
Safety of a drug-coated balloon for heart artery blockages
This study tests a special balloon coated with a drug called sirolimus to open blocked heart arteries. It may be an option for people with coronary artery disease who need a less invasive treatment.
Vigo, PontevedraAges 18 years+ - NCT07091682Recruiting
A trial of a dissolvable heart stent for long blockages
This trial tests a new type of stent made from magnesium that slowly dissolves over time. It is for people who have a long blockage in a heart artery that has not been treated before and may be a good option for those who are stable and have not had a recent heart attack.
ErfurtAges 18–80 - NCT07303439Recruiting
Comparing heart artery treatments in people with diabetes
This study compares using a special medicated balloon plus a medicated stent versus using just one of them to open blocked heart arteries in people with diabetes. It aims to find which treatment works better to keep arteries open longer.
Dublin, County DublinAges 18 years+ - NCT06400290Recruiting
Balloon test to find which artery causes chest pain
This study tests a new way to find which blocked heart arteries are causing your chest pain. During a stent procedure, doctors will briefly block each artery to see which one triggers your symptoms. This might help them decide which blockages to treat.
BasildonAges 18 years+ - NCT06899399Recruiting
Stent study for asymptomatic carotid artery blockage
This trial tests a stent procedure to open a severely blocked carotid artery in people who have not had a stroke or mini-stroke from that blockage recently. It aims to see if the procedure is safe and effective for preventing future strokes.
BeijingAges 40–80 - NCT07324720Recruiting
Comparing ischemia vs plaque risk for high-risk artery disease
This trial compares two ways to decide which heart artery blockages need treatment: one looks at blood flow, the other at plaque buildup and risk. It's for people with high-risk blockages to see which approach leads to better outcomes.
Seoul, Main BuildingAges 19 years+ - NCT07613996Recruiting
Blood Flow Measurement During Heart Imaging
This study examines how a special measurement technique works when blood vessels are dilated during a heart imaging procedure. It may help doctors better assess whether narrowing in your heart arteries needs treatment.
Shanghai, Please SelectAges 18 years+ - NCT06959524Recruiting
AGENT balloon for new heart artery blockages
This trial tests a drug-coated balloon (AGENT DCB) versus standard angioplasty/stenting for new blockages in heart arteries. It aims to see if the coated balloon works better and is safe for people who haven't had prior stents in that spot.
La Jolla, CaliforniaAges 18 years+ - NCT05491668Recruiting
Testing heart artery narrowing before planned stent procedure
This study checks how severely blocked a coronary artery is using measurements taken during a planned heart catheterization, to help guide whether and how to do a stent (PCI). It may help doctors choose the best treatment plan for people with about 70% or more narrowing.
Boston, MassachusettsAges 18 years+ - NCT07195149RecruitingPhase 3
Aspirin dose comparison after bypass surgery
This trial tests whether a lower dose of aspirin combined with another blood thinner (prasugrel) after bypass surgery is as safe and effective as a higher dose. It is for people with stable heart disease who are scheduled for bypass surgery and have not had a recent heart attack.
BialystokAges 18 years+ - NCT04973579Recruiting
Stent plus heart surgery for high risk carotid patients
This trial looks at whether doing carotid artery stenting at the same time as heart surgery is safe and effective for people at high risk of stroke around the time of surgery. It targets people with significant carotid narrowing who also need heart surgery for specific heart problems.
KrakowAges 18 years+ - NCT06939374Recruiting
Freezing heart arteries to stabilize high-risk plaques
This study tests a special cooling balloon to freeze and stabilize dangerous plaques in heart arteries that are not the main cause of your current symptoms. It aims to prevent future heart attacks.
AalstAges 18 years+ - NCT07463664Recruiting
Drug-coated balloons for blocked heart arteries
This trial tests whether a drug-coated balloon, used without a permanent stent, can safely open completely blocked heart arteries that have been blocked for at least 3 months. It may offer an option that avoids leaving a metal stent behind.
Beijing, Beijing MunicipalityAges 18–80 - NCT07232069RecruitingPhase 3
Early heart disease trial for women and men with mild plaque buildup
This trial tests whether two medicines, a statin and colchicine, can slow or stop early heart artery plaque from growing in people who have mild plaque but no heart disease symptoms yet. It uses special CT scans to measure plaque over 2 years.
Birmingham, AlabamaAges 30–60 - NCT06489119Recruiting
Studying plaque types in coronary artery disease with advanced imaging
This trial uses advanced imaging (OCT) and single-cell analysis to study different types of plaque in people with coronary artery disease. It aims to understand how these plaque types differ at a cellular level, which could lead to better treatments.
Harbin, HeilongjiangAges 18–85 - NCT07368933Recruiting
A drug-coated balloon for heart artery blockages
This trial tests a balloon coated with two drugs to treat narrowed or re-narrowed arteries in the heart. It may help people with chest pain or recent mild heart attacks who need a procedure to open a blockage.
BarcelonaAges 18 years+ - NCT07669987Recruiting
Heart bypass surgery and artery imaging study
This study looks at whether a special imaging test called QFR, done before heart bypass surgery, can help predict how well the radial artery graft will work shortly after surgery. If you have severe blockages in your heart arteries and are scheduled for bypass surgery, this trial may be relevant.
Beijing, Beijing MunicipalityAges 18–80 - NCT05775445Recruiting
People with very blocked or very normal coronary arteries
This study compares people with very severe coronary artery disease to those without significant disease, using heart imaging data. It aims to understand what differs between extreme cases and how that information could guide future care.
SingaporeAges 21–99 - NCT07341932Recruiting
Heart mapping test for stable coronary artery disease treatment
This trial tests whether a non-invasive heart mapping technique can guide treatment for stable coronary artery disease, potentially avoiding more expensive or invasive tests. You may join if you have stable angina and a blockage of 50-90% in a major heart artery.
Beijing, Beijing MunicipalityAges 18–80 - NCT06603363Recruiting
Statin effects on heart artery plaques seen on CT scans
This trial studies how short-term statin therapy changes plaque buildup in heart arteries. It uses CT scans to see if statins can make plaques more stable and reduce heart risks.
Budapest, BudapestAges 45–75 - NCT05908331Recruiting
Balloon treatment test for narrowed stents in heart arteries
This trial tests whether a special drug-coated balloon (“MagicTouch”) can treat re-narrowing inside a previously placed stent. It may help patients whose stent has become blocked again, by improving blood flow and reducing repeat narrowing.
Birmingham, AlabamaAges 18–110 - NCT06261866Recruiting
Heart imaging for moderate blockages in stable heart disease
This trial tests whether combining two advanced imaging tests (FFR and OCT) can help doctors better decide treatment for moderate blockages in heart arteries. If you have stable chest pain or a positive stress test and a moderate narrowing, this study may help guide your care.
WarsawAges 18 years+
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Common questions
- Are there clinical trials for left main coronary artery stenosis?
- Yes. Clin2 currently lists 87 recruiting left main coronary artery stenosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a left main coronary artery stenosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a left main coronary artery stenosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.